PT2994479T - Expressão modificada de prolil-4-hidroxilase em physcoitrella patens - Google Patents
Expressão modificada de prolil-4-hidroxilase em physcoitrella patensInfo
- Publication number
- PT2994479T PT2994479T PT14720988T PT14720988T PT2994479T PT 2994479 T PT2994479 T PT 2994479T PT 14720988 T PT14720988 T PT 14720988T PT 14720988 T PT14720988 T PT 14720988T PT 2994479 T PT2994479 T PT 2994479T
- Authority
- PT
- Portugal
- Prior art keywords
- physcoitrella
- patens
- prolyl
- hydroxylase
- modified expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
- C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1308120.3A GB201308120D0 (en) | 2013-05-06 | 2013-05-06 | Recombinant protein and method for its production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2994479T true PT2994479T (pt) | 2019-09-30 |
Family
ID=48627341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT14720988T PT2994479T (pt) | 2013-05-06 | 2014-05-05 | Expressão modificada de prolil-4-hidroxilase em physcoitrella patens |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10174334B2 (pt) |
| EP (1) | EP2994479B1 (pt) |
| JP (1) | JP6588892B2 (pt) |
| KR (1) | KR101906442B1 (pt) |
| AU (1) | AU2014264732B2 (pt) |
| BR (1) | BR112015027982A2 (pt) |
| CA (1) | CA2911083C (pt) |
| DK (1) | DK2994479T3 (pt) |
| ES (1) | ES2744993T3 (pt) |
| GB (1) | GB201308120D0 (pt) |
| HR (1) | HRP20191556T1 (pt) |
| LT (1) | LT2994479T (pt) |
| PL (1) | PL2994479T3 (pt) |
| PT (1) | PT2994479T (pt) |
| SI (1) | SI2994479T1 (pt) |
| WO (1) | WO2014180793A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023513307A (ja) * | 2020-02-14 | 2023-03-30 | モダン メドウ，インコーポレイテッド | アミノ酸をヒドロキシル化するための単量体タンパク質及び生成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001029242A2 (en) | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| KR100389141B1 (ko) | 2000-05-18 | 2003-06-25 | 동아제약 주식회사 | 인간 에리스로포이에틴을 고효율로 발현하는 재조합세포주 및 이의 제조방법 |
| WO2006035442A2 (en) | 2004-09-29 | 2006-04-06 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
| ATE472605T1 (de) * | 2005-07-12 | 2010-07-15 | Greenovation Biotech Gmbh | Verbesserungen der proteinproduktion oder in zusammenhang damit |
-
2013
- 2013-05-06 GB GBGB1308120.3A patent/GB201308120D0/en not_active Ceased
-
2014
- 2014-05-05 KR KR1020157031911A patent/KR101906442B1/ko active IP Right Grant
- 2014-05-05 WO PCT/EP2014/059132 patent/WO2014180793A1/en active Application Filing
- 2014-05-05 EP EP14720988.6A patent/EP2994479B1/en active Active
- 2014-05-05 US US14/889,254 patent/US10174334B2/en not_active Expired - Fee Related
- 2014-05-05 PT PT14720988T patent/PT2994479T/pt unknown
- 2014-05-05 DK DK14720988.6T patent/DK2994479T3/da active
- 2014-05-05 AU AU2014264732A patent/AU2014264732B2/en not_active Ceased
- 2014-05-05 SI SI201431350T patent/SI2994479T1/sl unknown
- 2014-05-05 JP JP2016512323A patent/JP6588892B2/ja not_active Expired - Fee Related
- 2014-05-05 CA CA2911083A patent/CA2911083C/en not_active Expired - Fee Related
- 2014-05-05 ES ES14720988T patent/ES2744993T3/es active Active
- 2014-05-05 PL PL14720988T patent/PL2994479T3/pl unknown
- 2014-05-05 BR BR112015027982A patent/BR112015027982A2/pt not_active IP Right Cessation
- 2014-05-05 LT LT14720988T patent/LT2994479T/lt unknown
-
2019
- 2019-08-29 HR HRP20191556 patent/HRP20191556T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014180793A1 (en) | 2014-11-13 |
| ES2744993T3 (es) | 2020-02-27 |
| JP2016519136A (ja) | 2016-06-30 |
| GB201308120D0 (en) | 2013-06-12 |
| DK2994479T3 (da) | 2019-09-23 |
| KR20150143593A (ko) | 2015-12-23 |
| JP6588892B2 (ja) | 2019-10-09 |
| US10174334B2 (en) | 2019-01-08 |
| AU2014264732A1 (en) | 2015-12-03 |
| EP2994479A1 (en) | 2016-03-16 |
| KR101906442B1 (ko) | 2018-12-07 |
| HRP20191556T1 (hr) | 2019-11-29 |
| AU2014264732B2 (en) | 2017-04-13 |
| CA2911083C (en) | 2020-09-15 |
| PL2994479T3 (pl) | 2020-02-28 |
| US20160208275A1 (en) | 2016-07-21 |
| SI2994479T1 (sl) | 2019-12-31 |
| EP2994479B1 (en) | 2019-06-19 |
| LT2994479T (lt) | 2019-10-25 |
| BR112015027982A2 (pt) | 2017-10-17 |
| CA2911083A1 (en) | 2014-11-13 |
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