PT2958903T - Processo para manufatura de vortioxetina - Google Patents
Processo para manufatura de vortioxetinaInfo
- Publication number
- PT2958903T PT2958903T PT147055248T PT14705524T PT2958903T PT 2958903 T PT2958903 T PT 2958903T PT 147055248 T PT147055248 T PT 147055248T PT 14705524 T PT14705524 T PT 14705524T PT 2958903 T PT2958903 T PT 2958903T
- Authority
- PT
- Portugal
- Prior art keywords
- vortioxetine
- manufacturing process
- manufacturing
- vortioxetine manufacturing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 title 1
- 229960002263 vortioxetine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361767883P | 2013-02-22 | 2013-02-22 | |
| DKPA201300104 | 2013-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2958903T true PT2958903T (pt) | 2017-05-26 |
Family
ID=59215387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT147055248T PT2958903T (pt) | 2013-02-22 | 2014-02-20 | Processo para manufatura de vortioxetina |
Country Status (37)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2605652T3 (pl) | 2010-08-18 | 2018-04-30 | Samumed, Llc | Diketony i hydroksyketony jako aktywatory szlaku sygnalizacji kateninowej |
| PE20151721A1 (es) | 2013-02-22 | 2015-12-07 | Samumed Llc | Y-dicetonas como activadores de la ruta de senalizacion de wnt/b-catenina |
| KR102165385B1 (ko) | 2014-08-20 | 2020-10-15 | 사뮤메드, 엘엘씨 | 피부 노화 및 주름의 치료 및 예방을 위한 감마-디케톤 |
| WO2016125191A2 (en) | 2015-02-04 | 2016-08-11 | Mylan Laboratories Limited | Processes for the preparation of vortioxetine hydrobromide |
| EP3274330A1 (en) | 2015-03-26 | 2018-01-31 | Cipla Limited | Method for making serotonin reuptake inhibitors |
| CN106279065A (zh) * | 2015-05-12 | 2017-01-04 | 北京深蓝海生物医药科技有限公司 | 一种氢溴酸沃替西汀的精制转晶方法 |
| JO3456B1 (ar) | 2015-05-13 | 2020-07-05 | H Lundbeck As | فيروتيوكسيتين بيروجلوتامات |
| CN109071374A (zh) * | 2016-02-08 | 2018-12-21 | Aaa化学公司 | 脂肪胺的芳基化 |
| BR112018003930A2 (pt) | 2016-07-01 | 2018-09-25 | H Lundbeck As | regimes de dosagem de vortioxetina para início rápido de efeito antidepressivo |
| US10519121B2 (en) | 2016-12-30 | 2019-12-31 | Apicore Us Llc | Process and novel polymorphic form of vortioxetine and its pharmaceutically acceptable salts |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| CN109912538B (zh) * | 2019-01-22 | 2021-03-12 | 安徽赛乐普制药有限公司 | 一种抗抑郁药沃替西汀的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| CN100457738C (zh) * | 2001-12-20 | 2009-02-04 | H·隆德贝克有限公司 | 芳氧基苯基和芳硫基苯基衍生物 |
| EP2439201B1 (en) * | 2006-06-16 | 2013-08-07 | H. Lundbeck A/S | Compounds with combined sert, 5-ht3 and 5-ht1a activity |
| TW201033181A (en) * | 2009-02-17 | 2010-09-16 | Lundbeck & Co As H | Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine |
-
2014
- 2014-02-20 RS RS20170399A patent/RS55932B1/sr unknown
- 2014-02-20 DK DK14705524.8T patent/DK2958903T3/en active
- 2014-02-20 PE PE2015001720A patent/PE20151589A1/es active IP Right Grant
- 2014-02-20 SM SM20170238T patent/SMT201700238T1/it unknown
- 2014-02-20 PT PT147055248T patent/PT2958903T/pt unknown
- 2014-02-20 KR KR1020157021985A patent/KR102230628B1/ko active Active
- 2014-02-20 EA EA201591349A patent/EA027756B1/ru not_active IP Right Cessation
- 2014-02-20 ME MEP-2017-91A patent/ME02671B/me unknown
- 2014-02-20 ES ES14705524.8T patent/ES2625380T3/es active Active
- 2014-02-20 CA CA2901821A patent/CA2901821A1/en not_active Abandoned
- 2014-02-20 SG SG11201506651SA patent/SG11201506651SA/en unknown
- 2014-02-20 AP AP2015008640A patent/AP2015008640A0/xx unknown
- 2014-02-20 SI SI201430214T patent/SI2958903T1/sl unknown
- 2014-02-20 BR BR112015019268-8A patent/BR112015019268B1/pt active IP Right Grant
- 2014-02-20 AU AU2014220735A patent/AU2014220735B2/en active Active
- 2014-02-20 UA UAA201509642A patent/UA116236C2/uk unknown
- 2014-02-20 US US14/767,350 patent/US9353073B2/en active Active
- 2014-02-20 MY MYPI2015002072A patent/MY172337A/en unknown
- 2014-02-20 MA MA38338A patent/MA38338B1/fr unknown
- 2014-02-20 MX MX2015010656A patent/MX362355B/es active IP Right Grant
- 2014-02-20 GE GEAP201413919A patent/GEP201706749B/en unknown
- 2014-02-20 PL PL14705524T patent/PL2958903T3/pl unknown
- 2014-02-20 JP JP2015558446A patent/JP6464098B2/ja active Active
- 2014-02-20 HR HRP20170607TT patent/HRP20170607T1/hr unknown
- 2014-02-20 EP EP14705524.8A patent/EP2958903B1/en active Active
- 2014-02-20 RU RU2015134407A patent/RU2652265C2/ru active
- 2014-02-20 WO PCT/EP2014/053313 patent/WO2014128207A1/en not_active Ceased
- 2014-02-20 CN CN201480009227.0A patent/CN104995181B/zh active Active
- 2014-02-20 LT LTEP14705524.8T patent/LT2958903T/lt unknown
-
2015
- 2015-08-06 TN TN2015000335A patent/TN2015000335A1/en unknown
- 2015-08-10 DO DO2015000187A patent/DOP2015000187A/es unknown
- 2015-08-11 IL IL240501A patent/IL240501B/en active IP Right Grant
- 2015-08-17 PH PH12015501807A patent/PH12015501807B1/en unknown
- 2015-08-18 CR CR20150423A patent/CR20150423A/es unknown
- 2015-08-18 CL CL2015002309A patent/CL2015002309A1/es unknown
- 2015-08-20 ZA ZA2015/06050A patent/ZA201506050B/en unknown
-
2017
- 2017-05-03 CY CY20171100483T patent/CY1118883T1/el unknown
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