SI2958903T1 - Proizvodni proces za vortioksetin - Google Patents
Proizvodni proces za vortioksetinInfo
- Publication number
- SI2958903T1 SI2958903T1 SI201430214T SI201430214T SI2958903T1 SI 2958903 T1 SI2958903 T1 SI 2958903T1 SI 201430214 T SI201430214 T SI 201430214T SI 201430214 T SI201430214 T SI 201430214T SI 2958903 T1 SI2958903 T1 SI 2958903T1
- Authority
- SI
- Slovenia
- Prior art keywords
- vortioxetine
- manufacturing process
- manufacturing
- vortioxetine manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
- C07F15/02—Iron compounds
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361767883P | 2013-02-22 | 2013-02-22 | |
| DKPA201300104 | 2013-02-22 | ||
| PCT/EP2014/053313 WO2014128207A1 (en) | 2013-02-22 | 2014-02-20 | Vortioxetine manufacturing process |
| EP14705524.8A EP2958903B1 (en) | 2013-02-22 | 2014-02-20 | Vortioxetine manufacturing process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2958903T1 true SI2958903T1 (sl) | 2017-09-29 |
Family
ID=59215387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201430214T SI2958903T1 (sl) | 2013-02-22 | 2014-02-20 | Proizvodni proces za vortioksetin |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US9353073B2 (sl) |
| EP (1) | EP2958903B1 (sl) |
| JP (1) | JP6464098B2 (sl) |
| KR (1) | KR102230628B1 (sl) |
| CN (1) | CN104995181B (sl) |
| AP (1) | AP2015008640A0 (sl) |
| AU (1) | AU2014220735B2 (sl) |
| BR (1) | BR112015019268B1 (sl) |
| CA (1) | CA2901821A1 (sl) |
| CL (1) | CL2015002309A1 (sl) |
| CR (1) | CR20150423A (sl) |
| CY (1) | CY1118883T1 (sl) |
| DK (1) | DK2958903T3 (sl) |
| DO (1) | DOP2015000187A (sl) |
| EA (1) | EA027756B1 (sl) |
| ES (1) | ES2625380T3 (sl) |
| GE (1) | GEP201706749B (sl) |
| HK (1) | HK1216098A1 (sl) |
| HR (1) | HRP20170607T1 (sl) |
| IL (1) | IL240501B (sl) |
| LT (1) | LT2958903T (sl) |
| MA (1) | MA38338B1 (sl) |
| ME (1) | ME02671B (sl) |
| MX (1) | MX362355B (sl) |
| MY (1) | MY172337A (sl) |
| PE (1) | PE20151589A1 (sl) |
| PH (1) | PH12015501807A1 (sl) |
| PL (1) | PL2958903T3 (sl) |
| PT (1) | PT2958903T (sl) |
| RS (1) | RS55932B1 (sl) |
| RU (1) | RU2652265C2 (sl) |
| SG (1) | SG11201506651SA (sl) |
| SI (1) | SI2958903T1 (sl) |
| TN (1) | TN2015000335A1 (sl) |
| UA (1) | UA116236C2 (sl) |
| WO (1) | WO2014128207A1 (sl) |
| ZA (1) | ZA201506050B (sl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2652363T3 (es) | 2010-08-18 | 2018-02-01 | Samumed, Llc | Dicetonas e hidroxicetonas como activadores de la vía de señalización de catenina |
| RU2680716C2 (ru) | 2013-02-22 | 2019-02-26 | СЭМЬЮМЕД, ЭлЭлСи | γ-ДИКЕТОНЫ В КАЧЕСТВЕ АКТИВАТОРОВ WNT/β-КАТЕНИНОВОГО СИГНАЛЬНОГО ПУТИ |
| EP3206686B1 (en) | 2014-08-20 | 2019-10-09 | Samumed, LLC | Gamma-diketones for treatment and prevention of aging skin and wrinkles |
| WO2016125191A2 (en) | 2015-02-04 | 2016-08-11 | Mylan Laboratories Limited | Processes for the preparation of vortioxetine hydrobromide |
| WO2016151328A1 (en) | 2015-03-26 | 2016-09-29 | Cipla Limited | Method for making serotonin reuptake inhibitors |
| CN106279065A (zh) * | 2015-05-12 | 2017-01-04 | 北京深蓝海生物医药科技有限公司 | 一种氢溴酸沃替西汀的精制转晶方法 |
| JO3456B1 (ar) | 2015-05-13 | 2020-07-05 | H Lundbeck As | فيروتيوكسيتين بيروجلوتامات |
| CN108473451B (zh) * | 2016-02-08 | 2022-07-15 | H.隆德贝克有限公司 | 1-[2-(2,4-二甲基-苯基硫烷基)-苯基]哌嗪的合成 |
| US9820984B1 (en) | 2016-07-01 | 2017-11-21 | H. Lundbeck A/S | Dosing regimens for fast onset of antidepressant effect |
| US10519121B2 (en) | 2016-12-30 | 2019-12-31 | Apicore Us Llc | Process and novel polymorphic form of vortioxetine and its pharmaceutically acceptable salts |
| CN109912538B (zh) * | 2019-01-22 | 2021-03-12 | 安徽赛乐普制药有限公司 | 一种抗抑郁药沃替西汀的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| ES2280595T3 (es) * | 2001-12-20 | 2007-09-16 | H. Lundbeck A/S | Derivados de ariloxifenilo y arilsulfanilfenilo. |
| SI2044043T2 (sl) * | 2006-06-16 | 2021-04-30 | H. Lundbeck A/S | 1-2(-2,4-dimetilfenilsulfanil)-fenil)piperazin hidrobromid kot spojina s kombinirano aktivnostjo ponovnega privzema serotonina, 5-ht3 in 5-ht1a za zdravljenje kognitivne motnje |
| TW201033181A (en) * | 2009-02-17 | 2010-09-16 | Lundbeck & Co As H | Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine |
-
2014
- 2014-02-20 KR KR1020157021985A patent/KR102230628B1/ko active IP Right Grant
- 2014-02-20 RU RU2015134407A patent/RU2652265C2/ru active
- 2014-02-20 CN CN201480009227.0A patent/CN104995181B/zh active Active
- 2014-02-20 DK DK14705524.8T patent/DK2958903T3/en active
- 2014-02-20 WO PCT/EP2014/053313 patent/WO2014128207A1/en active Application Filing
- 2014-02-20 MY MYPI2015002072A patent/MY172337A/en unknown
- 2014-02-20 UA UAA201509642A patent/UA116236C2/uk unknown
- 2014-02-20 US US14/767,350 patent/US9353073B2/en active Active
- 2014-02-20 MX MX2015010656A patent/MX362355B/es active IP Right Grant
- 2014-02-20 ES ES14705524.8T patent/ES2625380T3/es active Active
- 2014-02-20 RS RS20170399A patent/RS55932B1/sr unknown
- 2014-02-20 MA MA38338A patent/MA38338B1/fr unknown
- 2014-02-20 LT LTEP14705524.8T patent/LT2958903T/lt unknown
- 2014-02-20 EP EP14705524.8A patent/EP2958903B1/en active Active
- 2014-02-20 AP AP2015008640A patent/AP2015008640A0/xx unknown
- 2014-02-20 ME MEP-2017-91A patent/ME02671B/me unknown
- 2014-02-20 BR BR112015019268-8A patent/BR112015019268B1/pt active IP Right Grant
- 2014-02-20 PE PE2015001720A patent/PE20151589A1/es active IP Right Grant
- 2014-02-20 SG SG11201506651SA patent/SG11201506651SA/en unknown
- 2014-02-20 PL PL14705524T patent/PL2958903T3/pl unknown
- 2014-02-20 GE GEAP201413919A patent/GEP201706749B/en unknown
- 2014-02-20 CA CA2901821A patent/CA2901821A1/en not_active Abandoned
- 2014-02-20 JP JP2015558446A patent/JP6464098B2/ja active Active
- 2014-02-20 PT PT147055248T patent/PT2958903T/pt unknown
- 2014-02-20 SI SI201430214T patent/SI2958903T1/sl unknown
- 2014-02-20 AU AU2014220735A patent/AU2014220735B2/en active Active
- 2014-02-20 EA EA201591349A patent/EA027756B1/ru not_active IP Right Cessation
-
2015
- 2015-08-06 TN TN2015000335A patent/TN2015000335A1/en unknown
- 2015-08-10 DO DO2015000187A patent/DOP2015000187A/es unknown
- 2015-08-11 IL IL240501A patent/IL240501B/en active IP Right Grant
- 2015-08-17 PH PH12015501807A patent/PH12015501807A1/en unknown
- 2015-08-18 CL CL2015002309A patent/CL2015002309A1/es unknown
- 2015-08-18 CR CR20150423A patent/CR20150423A/es unknown
- 2015-08-20 ZA ZA2015/06050A patent/ZA201506050B/en unknown
-
2016
- 2016-04-08 HK HK16104011.9A patent/HK1216098A1/zh unknown
-
2017
- 2017-04-18 HR HRP20170607TT patent/HRP20170607T1/hr unknown
- 2017-05-03 CY CY20171100483T patent/CY1118883T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2520596B (en) | Manufacturing method | |
| IL243207B (en) | Process for manufacturing 4 -propargylated amino-benzoxazinones | |
| HK1216098A1 (zh) | 沃替西汀生產方法 | |
| GB201312991D0 (en) | Process | |
| GB201307334D0 (en) | Process | |
| GB201321440D0 (en) | Process | |
| GB201416005D0 (en) | Process | |
| GB201322454D0 (en) | Process | |
| GB201421428D0 (en) | Process | |
| GB201401963D0 (en) | Process | |
| GB201318888D0 (en) | Process | |
| GB201421426D0 (en) | Process | |
| GB201401922D0 (en) | Process | |
| GB201322273D0 (en) | Process | |
| GB201314334D0 (en) | Process | |
| GB201302441D0 (en) | Process | |
| GB201320869D0 (en) | Process | |
| GB201307327D0 (en) | Process | |
| GB201300073D0 (en) | Process | |
| GB201413623D0 (en) | Process | |
| GB201323151D0 (en) | Process | |
| GB201307951D0 (en) | Process | |
| GB201316253D0 (en) | Process | |
| GB201303604D0 (en) | Manufacturing process | |
| GB201418099D0 (en) | Process |