PT2958903T - Processo para manufatura de vortioxetina - Google Patents
Processo para manufatura de vortioxetinaInfo
- Publication number
- PT2958903T PT2958903T PT147055248T PT14705524T PT2958903T PT 2958903 T PT2958903 T PT 2958903T PT 147055248 T PT147055248 T PT 147055248T PT 14705524 T PT14705524 T PT 14705524T PT 2958903 T PT2958903 T PT 2958903T
- Authority
- PT
- Portugal
- Prior art keywords
- vortioxetine
- manufacturing process
- manufacturing
- vortioxetine manufacturing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 title 1
- 229960002263 vortioxetine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361767883P | 2013-02-22 | 2013-02-22 | |
| DKPA201300104 | 2013-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2958903T true PT2958903T (pt) | 2017-05-26 |
Family
ID=59215387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT147055248T PT2958903T (pt) | 2013-02-22 | 2014-02-20 | Processo para manufatura de vortioxetina |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US9353073B2 (pt) |
| EP (1) | EP2958903B1 (pt) |
| JP (1) | JP6464098B2 (pt) |
| KR (1) | KR102230628B1 (pt) |
| CN (1) | CN104995181B (pt) |
| AP (1) | AP2015008640A0 (pt) |
| AU (1) | AU2014220735B2 (pt) |
| BR (1) | BR112015019268B1 (pt) |
| CA (1) | CA2901821A1 (pt) |
| CL (1) | CL2015002309A1 (pt) |
| CR (1) | CR20150423A (pt) |
| CY (1) | CY1118883T1 (pt) |
| DK (1) | DK2958903T3 (pt) |
| DO (1) | DOP2015000187A (pt) |
| EA (1) | EA027756B1 (pt) |
| ES (1) | ES2625380T3 (pt) |
| GE (1) | GEP201706749B (pt) |
| HK (1) | HK1216098A1 (pt) |
| HR (1) | HRP20170607T1 (pt) |
| IL (1) | IL240501B (pt) |
| LT (1) | LT2958903T (pt) |
| MA (1) | MA38338B1 (pt) |
| ME (1) | ME02671B (pt) |
| MX (1) | MX362355B (pt) |
| MY (1) | MY172337A (pt) |
| PE (1) | PE20151589A1 (pt) |
| PH (1) | PH12015501807B1 (pt) |
| PL (1) | PL2958903T3 (pt) |
| PT (1) | PT2958903T (pt) |
| RS (1) | RS55932B1 (pt) |
| RU (1) | RU2652265C2 (pt) |
| SG (1) | SG11201506651SA (pt) |
| SI (1) | SI2958903T1 (pt) |
| TN (1) | TN2015000335A1 (pt) |
| UA (1) | UA116236C2 (pt) |
| WO (1) | WO2014128207A1 (pt) |
| ZA (1) | ZA201506050B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3311666T3 (da) | 2010-08-18 | 2021-06-28 | Biosplice Therapeutics Inc | Diketoner og hydroxyketoner som aktivatorer af catenin-signalvejen |
| EP2968249B1 (en) | 2013-02-22 | 2018-11-14 | Samumed, LLC | Gamma-diketones as wnt/beta -catenin signaling pathway activators |
| KR102165385B1 (ko) | 2014-08-20 | 2020-10-15 | 사뮤메드, 엘엘씨 | 피부 노화 및 주름의 치료 및 예방을 위한 감마-디케톤 |
| WO2016125191A2 (en) | 2015-02-04 | 2016-08-11 | Mylan Laboratories Limited | Processes for the preparation of vortioxetine hydrobromide |
| US20180072690A1 (en) | 2015-03-26 | 2018-03-15 | Cipla Limited | Methods for Making Serotonin Reuptake Inhibitors |
| CN106279065A (zh) * | 2015-05-12 | 2017-01-04 | 北京深蓝海生物医药科技有限公司 | 一种氢溴酸沃替西汀的精制转晶方法 |
| JO3456B1 (ar) | 2015-05-13 | 2020-07-05 | H Lundbeck As | فيروتيوكسيتين بيروجلوتامات |
| DK3414216T3 (da) * | 2016-02-08 | 2021-01-25 | Aaa Chemistry Aps | Arylering af alifatiske aminer |
| KR20190025556A (ko) | 2016-07-01 | 2019-03-11 | 하. 룬드벡 아크티에셀스카브 | 항우울 효과의 신속한 개시를 위한 보티옥세틴 투여 요법 |
| US10519121B2 (en) | 2016-12-30 | 2019-12-31 | Apicore Us Llc | Process and novel polymorphic form of vortioxetine and its pharmaceutically acceptable salts |
| CN109912538B (zh) * | 2019-01-22 | 2021-03-12 | 安徽赛乐普制药有限公司 | 一种抗抑郁药沃替西汀的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| CN100457738C (zh) * | 2001-12-20 | 2009-02-04 | H·隆德贝克有限公司 | 芳氧基苯基和芳硫基苯基衍生物 |
| PL2044043T5 (pl) * | 2006-06-16 | 2022-05-02 | H. Lundbeck A/S | Bromowodorek 1-[2-(2,4-dimetylofenylosulfanylo)fenylo]piperazyny jako związek o połączonym działaniu wychwytu zwrotnego serotoniny i działaniu na 5-ht3 i 5-ht1a do leczenia upośledzenia funckji poznawczych |
| TW201033181A (en) * | 2009-02-17 | 2010-09-16 | Lundbeck & Co As H | Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine |
-
2014
- 2014-02-20 MX MX2015010656A patent/MX362355B/es active IP Right Grant
- 2014-02-20 PT PT147055248T patent/PT2958903T/pt unknown
- 2014-02-20 BR BR112015019268-8A patent/BR112015019268B1/pt active IP Right Grant
- 2014-02-20 AU AU2014220735A patent/AU2014220735B2/en active Active
- 2014-02-20 LT LTEP14705524.8T patent/LT2958903T/lt unknown
- 2014-02-20 EA EA201591349A patent/EA027756B1/ru not_active IP Right Cessation
- 2014-02-20 AP AP2015008640A patent/AP2015008640A0/xx unknown
- 2014-02-20 ME MEP-2017-91A patent/ME02671B/me unknown
- 2014-02-20 PE PE2015001720A patent/PE20151589A1/es active IP Right Grant
- 2014-02-20 SG SG11201506651SA patent/SG11201506651SA/en unknown
- 2014-02-20 UA UAA201509642A patent/UA116236C2/uk unknown
- 2014-02-20 PL PL14705524T patent/PL2958903T3/pl unknown
- 2014-02-20 EP EP14705524.8A patent/EP2958903B1/en active Active
- 2014-02-20 GE GEAP201413919A patent/GEP201706749B/en unknown
- 2014-02-20 RU RU2015134407A patent/RU2652265C2/ru active
- 2014-02-20 RS RS20170399A patent/RS55932B1/sr unknown
- 2014-02-20 CA CA2901821A patent/CA2901821A1/en not_active Abandoned
- 2014-02-20 US US14/767,350 patent/US9353073B2/en active Active
- 2014-02-20 ES ES14705524.8T patent/ES2625380T3/es active Active
- 2014-02-20 SI SI201430214T patent/SI2958903T1/sl unknown
- 2014-02-20 WO PCT/EP2014/053313 patent/WO2014128207A1/en active Application Filing
- 2014-02-20 DK DK14705524.8T patent/DK2958903T3/en active
- 2014-02-20 CN CN201480009227.0A patent/CN104995181B/zh active Active
- 2014-02-20 MA MA38338A patent/MA38338B1/fr unknown
- 2014-02-20 MY MYPI2015002072A patent/MY172337A/en unknown
- 2014-02-20 JP JP2015558446A patent/JP6464098B2/ja active Active
- 2014-02-20 KR KR1020157021985A patent/KR102230628B1/ko active IP Right Grant
-
2015
- 2015-08-06 TN TN2015000335A patent/TN2015000335A1/en unknown
- 2015-08-10 DO DO2015000187A patent/DOP2015000187A/es unknown
- 2015-08-11 IL IL240501A patent/IL240501B/en active IP Right Grant
- 2015-08-17 PH PH12015501807A patent/PH12015501807B1/en unknown
- 2015-08-18 CL CL2015002309A patent/CL2015002309A1/es unknown
- 2015-08-18 CR CR20150423A patent/CR20150423A/es unknown
- 2015-08-20 ZA ZA2015/06050A patent/ZA201506050B/en unknown
-
2016
- 2016-04-08 HK HK16104011.9A patent/HK1216098A1/zh unknown
-
2017
- 2017-04-18 HR HRP20170607TT patent/HRP20170607T1/hr unknown
- 2017-05-03 CY CY20171100483T patent/CY1118883T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2520596B (en) | Manufacturing method | |
| IL243207B (en) | Process for manufacturing 4 -propargylated amino-benzoxazinones | |
| HK1216098A1 (zh) | 沃替西汀生產方法 | |
| GB201312991D0 (en) | Process | |
| GB201307334D0 (en) | Process | |
| GB201321440D0 (en) | Process | |
| GB201416005D0 (en) | Process | |
| GB201322454D0 (en) | Process | |
| GB201421428D0 (en) | Process | |
| GB201401963D0 (en) | Process | |
| GB201318888D0 (en) | Process | |
| GB201421426D0 (en) | Process | |
| GB201401922D0 (en) | Process | |
| GB201322273D0 (en) | Process | |
| GB201314334D0 (en) | Process | |
| GB201302441D0 (en) | Process | |
| GB201320869D0 (en) | Process | |
| GB201307327D0 (en) | Process | |
| GB201300073D0 (en) | Process | |
| GB201413623D0 (en) | Process | |
| GB201323151D0 (en) | Process | |
| GB201307951D0 (en) | Process | |
| GB201316253D0 (en) | Process | |
| GB201303604D0 (en) | Manufacturing process | |
| GB201418099D0 (en) | Process |