PT2582366E - Combinação terapêutica para o tratamento da dor - Google Patents

Combinação terapêutica para o tratamento da dor Download PDF

Info

Publication number
PT2582366E
PT2582366E PT117301994T PT11730199T PT2582366E PT 2582366 E PT2582366 E PT 2582366E PT 117301994 T PT117301994 T PT 117301994T PT 11730199 T PT11730199 T PT 11730199T PT 2582366 E PT2582366 E PT 2582366E
Authority
PT
Portugal
Prior art keywords
pain
treatment
therapeutic combination
therapeutic
combination
Prior art date
Application number
PT117301994T
Other languages
English (en)
Portuguese (pt)
Inventor
Klaus Schiene
Petra Bloms-Funke
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42395008&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2582366(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PT2582366E publication Critical patent/PT2582366E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT117301994T 2010-06-15 2011-06-14 Combinação terapêutica para o tratamento da dor PT2582366E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10006202 2010-06-15

Publications (1)

Publication Number Publication Date
PT2582366E true PT2582366E (pt) 2016-01-26

Family

ID=42395008

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117301994T PT2582366E (pt) 2010-06-15 2011-06-14 Combinação terapêutica para o tratamento da dor

Country Status (29)

Country Link
US (3) US8846765B2 (enExample)
EP (2) EP2582366B1 (enExample)
JP (3) JP6133772B2 (enExample)
KR (1) KR101831616B1 (enExample)
CN (1) CN103108631B (enExample)
AR (1) AR081931A1 (enExample)
AU (2) AU2011267474B2 (enExample)
BR (1) BR112012031836A2 (enExample)
CA (1) CA2796774C (enExample)
CL (1) CL2012002551A1 (enExample)
CO (1) CO6602157A2 (enExample)
CY (1) CY1117118T1 (enExample)
DK (1) DK2582366T3 (enExample)
EC (2) ECSP12012217A (enExample)
ES (1) ES2560676T3 (enExample)
HK (1) HK1215787A1 (enExample)
HR (1) HRP20151327T1 (enExample)
HU (1) HUE026619T2 (enExample)
IL (1) IL221926A (enExample)
MX (1) MX2012014482A (enExample)
NZ (1) NZ602625A (enExample)
PE (2) PE20130243A1 (enExample)
PL (1) PL2582366T3 (enExample)
PT (1) PT2582366E (enExample)
RS (1) RS54439B1 (enExample)
RU (2) RU2589692C2 (enExample)
SI (1) SI2582366T1 (enExample)
WO (1) WO2011157391A1 (enExample)
ZA (1) ZA201208646B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011267474B2 (en) * 2010-06-15 2016-05-26 Grünenthal GmbH Pharmaceutical combination for the treatment of pain
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
PE20141906A1 (es) * 2012-03-12 2014-12-05 Janssen Pharmaceutica Nv Esketamina para el tratamiento de la depresion refractaria al tratamiento o resistente al tratamiento
CA3128321C (en) 2013-01-22 2023-12-05 Vistagen Therapeutics, Inc. Dosage forms and therapeutic uses of l-4-chlorokynurenine
EP3636251B1 (en) 2013-03-15 2022-01-19 Janssen Pharmaceutica NV Pharmaceutical composition of s-ketamine hydrochloride
CN103655523A (zh) * 2013-12-24 2014-03-26 南京艾德凯腾生物医药有限责任公司 他喷他多组合物
US20170072005A1 (en) * 2014-05-06 2017-03-16 Northwestern University Combinations of nmdar modulating compounds
MX2017001908A (es) 2014-08-13 2017-08-08 Janssen Pharmaceutica Nv Metodo para el tratamiento de la depresion.
WO2016044150A1 (en) 2014-09-15 2016-03-24 Janssen Pharmaceutica Nv VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
AU2016288188B2 (en) 2015-06-27 2021-08-05 Shenox Pharmaceuticals, Llc Ketamine transdermal delivery system
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
WO2019126108A1 (en) 2017-12-22 2019-06-27 Janssen Pharmaceutica Nv Esketamine for the treatment of depression
CA3096671C (en) 2018-04-12 2025-09-16 Anavex Life Sciences Corp. CRYSTALLINE POLYMORPHIC COMPOSITIONS A2-73 OF MATERIAL AND THEIR METHODS OF USE
JP2022524008A (ja) 2019-03-05 2022-04-27 ヤンセン ファーマシューティカルズ,インコーポレーテッド うつ病の治療のためのエスケタミン

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391142A (en) 1966-02-09 1968-07-02 Lilly Co Eli Adamantyl secondary amines
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US5472711A (en) 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
US5330761A (en) 1993-01-29 1994-07-19 Edward Mendell Co. Inc. Bioadhesive tablet for non-systemic use products
US5455046A (en) 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5399362A (en) 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
US6248789B1 (en) * 1996-08-29 2001-06-19 Stuart L. Weg Administration of ketamine to manage pain and to reduce drug dependency
US6007841A (en) * 1998-03-13 1999-12-28 Algos Pharmaceutical Corporation Analgesic composition and method for treating pain
KR100762018B1 (ko) * 1998-07-16 2007-10-04 메모리얼 슬로안-케터링 캔서 센터 오피오이드 진통제 및 엔엠디에이 길항제를 함유하는 국소조성물
DE10005302A1 (de) * 2000-02-07 2002-01-17 Gruenenthal Gmbh Substituierte 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate
US20010036943A1 (en) 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
PE20030527A1 (es) * 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
DE10163421A1 (de) 2001-12-21 2003-07-31 Gruenenthal Gmbh Verwendung von (+)-(1S,2S)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)phenol als Antiemetikum
JP2003201254A (ja) * 2001-12-28 2003-07-18 Hisamitsu Pharmaceut Co Inc 鎮痛剤活性増強剤の治療上有効な血中濃度を維持するための製剤
JP2003210254A (ja) * 2002-01-18 2003-07-29 Nihon Form Service Co Ltd 車椅子専用ラック
JP2006500395A (ja) * 2002-09-09 2006-01-05 エンド ファーマシューティカルズ インコーポレーテッド 組み合わされた即時放出及び徐放の鎮痛組成物
US7273889B2 (en) * 2002-09-25 2007-09-25 Innovative Drug Delivery Systems, Inc. NMDA receptor antagonist formulation with reduced neurotoxicity
WO2007087452A2 (en) * 2006-01-27 2007-08-02 Theraquest Biosciences, Llc Abuse resistant and extended release formulations and method of use thereof
MX2008013828A (es) 2006-04-28 2008-11-10 Gruenenthal Gmbh Combinacion farmaceutica que comprende 3-(3-dimetilanimo-1-etil-2- metil-propil)-fenol y un nsaid.
EP2012764B1 (en) 2006-04-28 2011-01-12 Grünenthal GmbH Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol
US20070254960A1 (en) 2006-04-28 2007-11-01 Gruenenthal Gmbh Pharmaceutical combination
EP1857463A1 (en) 2006-05-03 2007-11-21 Ebewe Pharma Ges.m.b.H. Nfg. KG Peptide having neuroprotective effects
CA2652667A1 (en) * 2006-06-08 2007-12-13 Schwarz Pharma Ag Therapeutic combination for painful medical conditions
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
DE102007012165A1 (de) * 2007-03-12 2008-09-18 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
WO2009067703A2 (en) * 2007-11-23 2009-05-28 Nectid, Inc. Tapentadol compositions
KR101616246B1 (ko) 2008-01-25 2016-05-02 그뤼넨탈 게엠베하 약제학적 투여형
US7872046B2 (en) * 2008-01-25 2011-01-18 Xenoport, Inc. Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
LT2735338T (lt) * 2008-09-05 2019-04-10 Grünenthal GmbH 3-(3-dimetilamino-1-etil-2-metil-propil)-fenolio ir pregabalino arba gabapentino farmacinis derinys
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
AU2011267474B2 (en) * 2010-06-15 2016-05-26 Grünenthal GmbH Pharmaceutical combination for the treatment of pain
SG188300A1 (en) 2010-09-21 2013-04-30 Purdue Pharma Lp Buprenorphine analogs
SG191288A1 (en) 2010-12-22 2013-07-31 Purdue Pharma Lp Encased tamper resistant controlled release dosage forms
EA028149B1 (ru) 2011-03-04 2017-10-31 Грюненталь Гмбх Парентеральное введение тапентадола
CA2868413C (en) 2012-04-17 2021-07-20 Purdue Pharma L.P. Systems and methods for treating an opioid-induced adverse pharmacodynamic response

Also Published As

Publication number Publication date
JP6133772B2 (ja) 2017-05-24
NZ602625A (en) 2014-03-28
US10813890B2 (en) 2020-10-27
AU2011267474A1 (en) 2013-01-10
ES2560676T3 (es) 2016-02-22
JP6197007B2 (ja) 2017-09-13
JP2017141277A (ja) 2017-08-17
CN103108631A (zh) 2013-05-15
US20140309311A1 (en) 2014-10-16
CO6602157A2 (es) 2013-01-18
BR112012031836A2 (pt) 2016-11-08
ECSP12012217A (es) 2012-11-30
CA2796774C (en) 2020-06-02
RU2013101515A (ru) 2014-07-20
HK1184370A1 (zh) 2014-01-24
AR081931A1 (es) 2012-10-31
SI2582366T1 (sl) 2016-02-29
CN103108631B (zh) 2015-08-26
EP2582366B1 (en) 2015-10-28
PE20130243A1 (es) 2013-03-22
RU2016119041A (ru) 2017-11-20
RU2589692C2 (ru) 2016-07-10
KR101831616B1 (ko) 2018-04-04
JP2013528629A (ja) 2013-07-11
ZA201208646B (en) 2013-09-25
AU2016219643A1 (en) 2016-09-15
HRP20151327T1 (hr) 2016-01-01
WO2011157391A1 (en) 2011-12-22
HK1215787A1 (en) 2016-09-15
CY1117118T1 (el) 2017-04-05
US20170333369A1 (en) 2017-11-23
IL221926A (en) 2015-08-31
EP2992877A1 (en) 2016-03-09
MX2012014482A (es) 2013-02-21
PL2582366T3 (pl) 2016-04-29
AU2016219643B2 (en) 2018-04-12
HUE026619T2 (en) 2016-06-28
PE20160531A1 (es) 2016-06-05
JP6423036B2 (ja) 2018-11-14
US20110306674A1 (en) 2011-12-15
US8846765B2 (en) 2014-09-30
JP2015232015A (ja) 2015-12-24
EP2582366A1 (en) 2013-04-24
CL2012002551A1 (es) 2012-11-09
KR20130111945A (ko) 2013-10-11
RU2675261C2 (ru) 2018-12-18
AU2011267474B2 (en) 2016-05-26
ECSP19047259A (es) 2019-07-31
RS54439B1 (sr) 2016-06-30
DK2582366T3 (en) 2015-12-07
CA2796774A1 (en) 2011-12-22

Similar Documents

Publication Publication Date Title
PT2582366E (pt) Combinação terapêutica para o tratamento da dor
PT2709604T (pt) Canabidivarina para utilização no tratamento de dor neuropática
BR112013011874A2 (pt) compostos e métodos para tratar dor
PT2632300T (pt) Almofada cervical para o tratamento de doenças da coluna cervical
IL222132B (en) Use of cannabidivarin for the preparation of medicaments for treating epilepsy or epileptic seizures
BRPI1012116A2 (pt) composição farmacêutica para o tratamento de doenças cardíacas
BR112013014583A2 (pt) composição farmacêutica, e, métodos para o tratamento de inflamação, para o tratamento da dor, e para preparar 3-metanossulfonilpropionitrila
BR112013018469A2 (pt) dispositivos e métodos para tratamento de tecidos
BR112012027707A2 (pt) dispositivo médico para tratar tecido rígido
BR112012018947A2 (pt) composição farmacêutica para tratamento e\ou prevenção do cancêr
FI20105569L (fi) Kehonsisäinen hoitolaite
HUE045367T2 (hu) Kombinált terápia diabétesz kezelésére
PT2627345E (pt) Formulações para o tratamento de distúrbios das vias respiratórias superiores
IL222890A0 (en) Medicaments for the treatment of il-1beta related conditions
CO6801718A2 (es) Composición terapéutica para el tratamiento de glioblastoma
BRPI1014528A2 (pt) compostos para tratamento de inflamação e dor
BR112012004836A2 (pt) pirazinilpiridinas úteis para o tratamento de doenças proliferativas
PT2525796T (pt) Solução aquosa incluindo 3-quinuclidinonas para o tratamento de doenças hiperproliferativas, auto-imunes e cardíacas
IL232434B (en) Medicine for medical treatment and/or improvement of sepsis
EP2614824A4 (en) THERAPEUTIC AGENT AGAINST PAIN
BR112013004683A2 (pt) "conjunto de cateter para tratamento de nervo"
BR112013015048A2 (pt) composição para o tratamento de distúrbios metabólicos
IL275636A (en) Medical combination for cancer treatment
BRPI1007399A2 (pt) Formulações de emulsão narcótica para o tratamento de dor de câncer
LT2531124T (lt) Prietaisai odos pažeidimams gydyti