PT2354218T - Estirpes de levedura que produzem colesterol e suas utilizações - Google Patents

Estirpes de levedura que produzem colesterol e suas utilizações

Info

Publication number
PT2354218T
PT2354218T PT101860245T PT10186024T PT2354218T PT 2354218 T PT2354218 T PT 2354218T PT 101860245 T PT101860245 T PT 101860245T PT 10186024 T PT10186024 T PT 10186024T PT 2354218 T PT2354218 T PT 2354218T
Authority
PT
Portugal
Prior art keywords
cholesterol
yeast strains
producing yeast
producing
strains
Prior art date
Application number
PT101860245T
Other languages
English (en)
Inventor
Pompon Denis
Dumas Bruno
Spagnoli Roberto
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PT2354218T publication Critical patent/PT2354218T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0493Steroids, e.g. cholesterol, testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT101860245T 2004-05-06 2005-05-02 Estirpes de levedura que produzem colesterol e suas utilizações PT2354218T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0404890A FR2869914B1 (fr) 2004-05-06 2004-05-06 Souches de levure produisant du cholesterol et leurs applications

Publications (1)

Publication Number Publication Date
PT2354218T true PT2354218T (pt) 2018-03-15

Family

ID=34946597

Family Applications (2)

Application Number Title Priority Date Filing Date
PT05763706T PT1745123E (pt) 2004-05-06 2005-05-02 Estirpes de levedura que produzem colesterol e suas utilizações
PT101860245T PT2354218T (pt) 2004-05-06 2005-05-02 Estirpes de levedura que produzem colesterol e suas utilizações

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT05763706T PT1745123E (pt) 2004-05-06 2005-05-02 Estirpes de levedura que produzem colesterol e suas utilizações

Country Status (31)

Country Link
US (2) US8211676B2 (pt)
EP (2) EP2354218B1 (pt)
JP (2) JP5053838B2 (pt)
KR (1) KR101252304B1 (pt)
CN (1) CN1981029B (pt)
AR (1) AR048938A1 (pt)
AU (1) AU2005252401B2 (pt)
BR (1) BRPI0509598B8 (pt)
CA (1) CA2562773C (pt)
CY (2) CY1113174T1 (pt)
DK (2) DK1745123T3 (pt)
ES (2) ES2390588T3 (pt)
FR (1) FR2869914B1 (pt)
HK (1) HK1107117A1 (pt)
HR (2) HRP20120806T1 (pt)
HU (1) HUE036218T2 (pt)
IL (2) IL178741A (pt)
LT (1) LT2354218T (pt)
MA (1) MA28570B1 (pt)
ME (1) ME01455B (pt)
MX (1) MXPA06012840A (pt)
NO (2) NO341207B1 (pt)
NZ (1) NZ551057A (pt)
PL (2) PL1745123T3 (pt)
PT (2) PT1745123E (pt)
RS (2) RS56952B1 (pt)
RU (1) RU2397245C2 (pt)
SG (3) SG10201501156WA (pt)
SI (1) SI2354218T1 (pt)
WO (1) WO2005121315A1 (pt)
ZA (1) ZA200609162B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60140141D1 (de) * 2000-11-14 2009-11-19 Vital Health Sciences Pty Ltd Zusammensetzungen umfassend Komplexe von Tocopherolphosphatderivaten
FR2869914B1 (fr) * 2004-05-06 2012-11-09 Aventis Pharma Sa Souches de levure produisant du cholesterol et leurs applications
DE102009022772A1 (de) 2009-05-21 2010-11-25 Organobalance Gmbh Mikroorganismus zur Expression eines humanen Membranproteins
KR101861387B1 (ko) 2009-12-03 2018-05-25 디에스엠 아이피 어셋츠 비.브이. 효모에 의한 비효모 스테롤의 제조
FR2961218A1 (fr) 2010-06-10 2011-12-16 Sanofi Aventis Methode de detection de composes modulateurs du metabolisme du cholesterol
WO2012095816A1 (en) 2011-01-14 2012-07-19 Sanofi Method for detecting the biological activity of alpha-synuclein
FR2976949B1 (fr) * 2011-06-21 2015-08-28 Sanofi Sa Procede de preparation de levures genetiquement transformees capables de produire une molecule d'interet a haut titre
US20130316462A1 (en) * 2012-05-25 2013-11-28 Health Diagnostic Laboratory, Inc. Rapid and high-throughput analysis of sterols/stanols or derivatives thereof
JP6533747B2 (ja) 2014-01-17 2019-06-19 協和発酵バイオ株式会社 7デヒドロコレステロール及びビタミンd3の製造法
EP3205728B1 (en) * 2014-10-08 2019-11-27 Kyowa Hakko Bio Co., Ltd. Process for producing 7-dehydrocholesterol and vitamin d3
CN104805027B (zh) * 2015-05-27 2018-04-27 天津大学 一种重组耶氏解脂酵母菌株及其构建方法和应用
US11466303B2 (en) * 2015-12-23 2022-10-11 Dsm Ip Assets B.V. Production of sterols in modified yeast
CN106754993B (zh) * 2017-02-17 2020-06-30 天津大学 一种基因、重组酿酒酵母菌株及其构建方法与应用
JP6909466B2 (ja) * 2017-07-25 2021-07-28 大陽日酸株式会社 標識代謝物の製造方法、代謝物の定量方法、及び標識代謝物製造キット
CN112626159B (zh) * 2021-01-07 2022-08-05 华东理工大学 利用工程酿酒酵母高效生产胆固醇的发酵培养基及其制备方法
CN114577925B (zh) * 2021-12-29 2024-02-02 西南大学 一种水样中粪甾醇类物质快速检测方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB613778A (en) 1946-07-02 1948-12-02 United Domestic Ind Ltd Improvements in or relating to the production of cholesterol
GB646227A (en) 1948-02-27 1950-11-15 Organon Labor Ltd Process for isolation of cholesterol from wool wax alcohols
US2650929A (en) 1948-02-27 1953-09-01 Hewett Colin Leslie Process for isolation of cholesterol from wool wax alcohols
GB690879A (en) 1950-07-21 1953-04-29 Organon Labor Ltd Process for the isolation of cholesterol from wool-wax alcohols
US2688623A (en) 1950-07-21 1954-09-07 Organon Labor Ltd Process for the isolation of cholesterol from wool-wax alcohols
CN1017820B (zh) * 1988-12-01 1992-08-12 韦斯普里米森本亚克 地下空间特别是矿区的排水方法
US5460949A (en) * 1990-11-15 1995-10-24 Amoco Corporation Method and composition for increasing the accumulation of squalene and specific sterols in yeast
IL116872A (en) 1995-02-15 2004-12-15 Aventis Pharma Sa Delta 5,7-Strol Reductase from Arbidopsis Thaliana
FR2774393B1 (fr) 1998-02-05 2000-03-24 Hoechst Marion Roussel Inc Souches de levure ayant le gene atf2 interrompu et leurs applications
FR2820145B1 (fr) 2001-01-31 2004-01-23 Aventis Pharma Sa Souche de levure produisant des steroides de facon autonome
JP2004141125A (ja) * 2002-08-28 2004-05-20 Mitsubishi Chemicals Corp 代謝工学的に改変されている真菌類およびそれを用いるステロール類の製造法
FR2869914B1 (fr) * 2004-05-06 2012-11-09 Aventis Pharma Sa Souches de levure produisant du cholesterol et leurs applications

Also Published As

Publication number Publication date
SG150408A1 (en) 2009-03-30
PT1745123E (pt) 2012-10-03
PL1745123T3 (pl) 2012-12-31
JP2007535960A (ja) 2007-12-13
CY1120394T1 (el) 2019-07-10
JP5053838B2 (ja) 2012-10-24
AU2005252401B2 (en) 2012-04-05
ME01455B (me) 2014-04-20
HUE036218T2 (hu) 2018-06-28
IL238365B (en) 2018-12-31
BRPI0509598A (pt) 2007-10-16
WO2005121315A1 (fr) 2005-12-22
KR20070007902A (ko) 2007-01-16
FR2869914B1 (fr) 2012-11-09
CN1981029A (zh) 2007-06-13
ZA200609162B (en) 2009-03-25
SG185179A1 (en) 2012-11-29
NO20065402L (no) 2007-01-18
CY1113174T1 (el) 2016-04-13
EP2354218A2 (fr) 2011-08-10
AR048938A1 (es) 2006-06-14
MA28570B1 (fr) 2007-05-02
IL238365A0 (en) 2015-06-30
AU2005252401A1 (en) 2005-12-22
ES2662971T3 (es) 2018-04-10
CN1981029B (zh) 2010-06-16
EP1745123A1 (fr) 2007-01-24
DK2354218T3 (en) 2018-03-26
IL178741A (en) 2015-07-30
NO341207B1 (no) 2017-09-11
US20120276586A1 (en) 2012-11-01
IL178741A0 (en) 2007-02-11
HK1107117A1 (en) 2008-03-28
US20090239837A1 (en) 2009-09-24
PL2354218T3 (pl) 2018-05-30
NO20171396A1 (no) 2007-01-18
US8211676B2 (en) 2012-07-03
EP1745123B1 (fr) 2012-07-11
RU2006143060A (ru) 2008-06-20
CA2562773A1 (fr) 2005-12-22
EP2354218B1 (fr) 2017-12-13
HRP20180433T1 (hr) 2018-04-20
RS52444B (en) 2013-02-28
NZ551057A (en) 2009-09-25
BRPI0509598B1 (pt) 2016-12-06
DK1745123T3 (da) 2012-10-22
NO343427B1 (no) 2019-03-04
LT2354218T (lt) 2018-03-26
HRP20120806T1 (hr) 2012-11-30
BRPI0509598B8 (pt) 2021-05-25
SG10201501156WA (en) 2015-04-29
JP5670310B2 (ja) 2015-02-18
US8685705B2 (en) 2014-04-01
RU2397245C2 (ru) 2010-08-20
ES2390588T3 (es) 2012-11-14
JP2012105651A (ja) 2012-06-07
RS56952B1 (sr) 2018-05-31
MXPA06012840A (es) 2007-02-15
KR101252304B1 (ko) 2013-04-08
FR2869914A1 (fr) 2005-11-11
CA2562773C (fr) 2016-12-20
EP2354218A3 (fr) 2012-01-18
SI2354218T1 (en) 2018-04-30

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