PT2310034E - Péptidos para o tratamento de beta-amiloidoses - Google Patents

Péptidos para o tratamento de beta-amiloidoses Download PDF

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Publication number
PT2310034E
PT2310034E PT97611537T PT09761153T PT2310034E PT 2310034 E PT2310034 E PT 2310034E PT 97611537 T PT97611537 T PT 97611537T PT 09761153 T PT09761153 T PT 09761153T PT 2310034 E PT2310034 E PT 2310034E
Authority
PT
Portugal
Prior art keywords
amyloidoses
peptides
treating beta
beta
treating
Prior art date
Application number
PT97611537T
Other languages
English (en)
Inventor
Frank Mattner
Markus Mandler
Christian Gieffers
Andrea Dolischka
Oleksandr Otava
Original Assignee
Affiris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiris Ag filed Critical Affiris Ag
Publication of PT2310034E publication Critical patent/PT2310034E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT97611537T 2008-06-12 2009-06-12 Péptidos para o tratamento de beta-amiloidoses PT2310034E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0095108A AT506819B1 (de) 2008-06-12 2008-06-12 Vakzin zur behandlung von alzheimer-krankheit

Publications (1)

Publication Number Publication Date
PT2310034E true PT2310034E (pt) 2014-06-05

Family

ID=41401982

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97611537T PT2310034E (pt) 2008-06-12 2009-06-12 Péptidos para o tratamento de beta-amiloidoses

Country Status (22)

Country Link
US (2) US8613931B2 (pt)
EP (1) EP2310034B9 (pt)
JP (2) JP2011522841A (pt)
KR (1) KR20110036808A (pt)
CN (1) CN102123727B (pt)
AT (3) AT506819B1 (pt)
AU (1) AU2009257169B2 (pt)
BR (1) BRPI0915137A2 (pt)
CA (1) CA2723991A1 (pt)
CY (1) CY1115316T1 (pt)
DK (1) DK2310034T3 (pt)
ES (1) ES2461492T3 (pt)
HK (1) HK1152470A1 (pt)
HR (1) HRP20140586T1 (pt)
IL (1) IL209895A (pt)
MX (1) MX2010013648A (pt)
PL (1) PL2310034T3 (pt)
PT (1) PT2310034E (pt)
RS (1) RS53236B (pt)
RU (1) RU2553345C2 (pt)
SI (1) SI2310034T1 (pt)
WO (1) WO2009149486A2 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011151076A2 (en) * 2010-06-04 2011-12-08 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin MONOCLONAL ANTIBODIES TARGETING Αβ OLIGOMERS
US20120328605A1 (en) * 2010-10-27 2012-12-27 Daniel Larocque Compositions and uses
US9617302B2 (en) * 2011-06-14 2017-04-11 National Taiwan University Peptide compounds for inhibition of platelet aggregation
GB201113570D0 (en) 2011-08-05 2011-09-21 Glaxosmithkline Biolog Sa Vaccine
PL2579042T3 (pl) 2011-10-04 2014-12-31 Affiris Ag Sposób wykrywania przeciwciał swoistych wobec Aß w próbce biologicznej
EP2659908A1 (en) * 2012-05-01 2013-11-06 Affiris AG Compositions
EP2787347A1 (en) 2013-04-03 2014-10-08 Affiris AG Method for detecting Aß-specific antibodies in a biological sample
WO2015165961A1 (en) 2014-04-29 2015-11-05 Affiris Ag Treatment and prevention of alzheimer's disease (ad)
CA2946929A1 (en) * 2014-04-29 2015-11-05 Affiris Ag Treatment and prevention of alzheimer's disease (ad)
CA2946931A1 (en) 2014-04-29 2015-11-05 Affiris Ag Treatment and prevention of alzheimer's disease (ad)
WO2015175769A1 (en) 2014-05-15 2015-11-19 Biogen Ma Inc. Methods for the detection of amyloid beta oligomers in biological samples
CN108350051A (zh) * 2015-11-09 2018-07-31 英属哥伦比亚大学 淀粉样蛋白β中的N-末端表位及其构象选择性抗体
KR20180085736A (ko) * 2015-11-09 2018-07-27 더 유니버시티 오브 브리티쉬 콜롬비아 아밀로이드 베타 중간-영역 내 에피토프 및 이에 대해 구조적으로 선택성인 항체
WO2017079835A1 (en) * 2015-11-09 2017-05-18 The University Of British Columbia Amyloid beta epitopes and antibodies thereto
ES2571055B1 (es) * 2016-02-15 2016-12-28 Araclon Biotech, S.L. Conjugado amiloide y usos y procedimientos del mismo
EP3478311A4 (en) * 2016-06-29 2021-01-06 The Regents of the University of California STRUCTURE-BASED PEPTIDE INHIBITORS OF THE ALPHA-SYNUCLEIN AGGREGATION
US20180125920A1 (en) 2016-11-09 2018-05-10 The University Of British Columbia Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
CA3064785A1 (en) * 2017-05-30 2018-12-06 The University Of British Columbia Epitopes in the rna recognition motif 1 (rrm1) of tdp-43 and misfolding-selective antibodies thereto
CN109985231A (zh) * 2018-01-02 2019-07-09 上海清流生物医药科技有限公司 一种蛋白在制备预防和治疗痴呆症的药物中的应用
MX2023003009A (es) * 2020-09-17 2023-04-10 Othair Prothena Ltd Vacuna de beta-amiloide para el tratamiento de la enfermedad de alzheimer.
CN112608926A (zh) * 2020-12-08 2021-04-06 安徽大千生物工程有限公司 一种用于检测β淀粉样蛋白的基因序列组、杂交瘤细胞组及胶乳增强免疫比浊法试剂盒
CN113061161B (zh) * 2021-04-02 2023-09-12 河南省农业科学院动物免疫学重点实验室 靶向amyloid-beta结构的抑制性肽配基及应用
WO2023077091A1 (en) * 2021-10-28 2023-05-04 Abbvie Inc. Anti-amyloid beta antibodies and methods of using the same
WO2023161526A1 (en) 2022-02-28 2023-08-31 Tridem Bioscience Gmbh & Co Kg A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US20110131679A2 (en) * 2000-04-19 2011-06-02 Thomas La Rosa Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
RU2294211C2 (ru) * 2001-01-19 2007-02-27 Цитос Байотекнолоджи Аг Композиция и способ для иммунизации, способ продуцирования неприродного, упорядоченного и повторяющегося массива антигенов
US20040265849A1 (en) 2002-11-22 2004-12-30 Applera Corporation Genetic polymorphisms associated with Alzheimer's disease, methods of detection and uses thereof
AT413945B (de) * 2003-01-14 2006-07-15 Mattner Frank Dr Impfstoff für die alzheimer-krankheit
US7358331B2 (en) * 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
US20050112555A1 (en) * 2003-09-03 2005-05-26 Smith Harold C. Cytidine deaminase activators, deoxycytidine deaminase activators, Vif antagonists, and methods of screening for molecules thereof
US20050176030A1 (en) 2003-10-28 2005-08-11 Li Gan Regulated nucleic acids in pathogenesis of Alzheimer's Disease
AT500483B1 (de) * 2004-07-13 2006-01-15 Mattner Frank Dr Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
AT413946B (de) 2004-07-13 2006-07-15 Mattner Frank Dr Impfstoff gegen die alzheimer-krankheit
GB0421639D0 (en) 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease
AU2005306997B2 (en) 2004-10-25 2012-07-05 Merck Sharp & Dohme Corp. Anti-ADDL antibodies and uses thereof
EP2397856B1 (en) * 2006-03-14 2013-11-13 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
EP2043687A4 (en) 2006-06-29 2010-03-17 Centocor Ortho Biotech Inc ANTI-AMYLOID ANTIBODIES, COMPOSITIONS, METHODS AND USES
WO2009091518A2 (en) * 2008-01-15 2009-07-23 Monsanto Technology, Llc Isolated novel nucleic acid and protein molecules from corn and methods of using those molecules to generate transgenic plant with enhanced agronomic traits

Also Published As

Publication number Publication date
SI2310034T1 (sl) 2014-05-30
IL209895A0 (en) 2011-02-28
JP2011522841A (ja) 2011-08-04
RS53236B (en) 2014-08-29
AU2009257169A1 (en) 2009-12-17
AT506819A1 (de) 2009-12-15
CN102123727B (zh) 2015-06-10
PL2310034T3 (pl) 2014-08-29
MX2010013648A (es) 2011-04-05
HK1152470A1 (en) 2012-03-02
IL209895A (en) 2015-09-24
EP2310034B1 (en) 2014-03-26
BRPI0915137A2 (pt) 2016-02-16
AU2009257169B2 (en) 2015-06-25
HRP20140586T1 (hr) 2014-09-12
WO2009149486A2 (en) 2009-12-17
CA2723991A1 (en) 2009-12-17
EP2310034B9 (en) 2014-12-17
AT509106A1 (de) 2011-06-15
US8613931B2 (en) 2013-12-24
AT506819B1 (de) 2011-06-15
ES2461492T3 (es) 2014-05-20
RU2011100126A (ru) 2012-07-20
US20130230545A1 (en) 2013-09-05
JP2015147771A (ja) 2015-08-20
CN102123727A (zh) 2011-07-13
DK2310034T3 (da) 2014-04-28
AT509105A1 (de) 2011-06-15
US20110097351A1 (en) 2011-04-28
KR20110036808A (ko) 2011-04-11
EP2310034A2 (en) 2011-04-20
WO2009149486A3 (en) 2010-06-10
JP6041917B2 (ja) 2016-12-14
AT509105B1 (de) 2011-12-15
CY1115316T1 (el) 2017-01-04
RU2553345C2 (ru) 2015-06-10
AT509106B1 (de) 2011-12-15

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