PT2153260T - Composição que compreende uma alta concentração de moléculas biologicamente ativas e processos de preparação da mesma - Google Patents

Composição que compreende uma alta concentração de moléculas biologicamente ativas e processos de preparação da mesma

Info

Publication number
PT2153260T
PT2153260T PT87562112T PT08756211T PT2153260T PT 2153260 T PT2153260 T PT 2153260T PT 87562112 T PT87562112 T PT 87562112T PT 08756211 T PT08756211 T PT 08756211T PT 2153260 T PT2153260 T PT 2153260T
Authority
PT
Portugal
Prior art keywords
preparing
processes
composition
same
biologically active
Prior art date
Application number
PT87562112T
Other languages
English (en)
Inventor
Draghia-Akli Ruxandra
Hebel Henry
Cai Ying
Original Assignee
Vgxi Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vgxi Inc filed Critical Vgxi Inc
Publication of PT2153260T publication Critical patent/PT2153260T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/12Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Sustainable Development (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT87562112T 2007-05-23 2008-05-23 Composição que compreende uma alta concentração de moléculas biologicamente ativas e processos de preparação da mesma PT2153260T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93979207P 2007-05-23 2007-05-23

Publications (1)

Publication Number Publication Date
PT2153260T true PT2153260T (pt) 2017-04-24

Family

ID=39669869

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87562112T PT2153260T (pt) 2007-05-23 2008-05-23 Composição que compreende uma alta concentração de moléculas biologicamente ativas e processos de preparação da mesma

Country Status (11)

Country Link
US (3) US20090004716A1 (pt)
EP (1) EP2153260B1 (pt)
JP (1) JP5793726B2 (pt)
KR (1) KR101497728B1 (pt)
CN (2) CN105567672A (pt)
AU (1) AU2008256681B2 (pt)
CA (1) CA2685069C (pt)
ES (1) ES2622418T3 (pt)
HR (1) HRP20170233T1 (pt)
PT (1) PT2153260T (pt)
WO (1) WO2008148010A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835620B2 (en) 2008-01-11 2014-09-16 Vgx Pharmaceuticals, Llc Vaccines against multiple subtypes of dengue virus
US7932356B1 (en) * 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
MX2013004655A (es) 2010-10-26 2013-08-27 Presidio Pharmaceuticals Inc Inhibidores del virus de la hepatitis c.
CA2827080C (en) 2011-02-11 2022-09-20 The Trustees Of The University Of Pennsylvania Nucleic acid molecule encoding hepatitis b virus core protein and vaccine comprising the same
US9238679B2 (en) 2011-02-11 2016-01-19 The Trustees Of The University Of Pennslyvania Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same
US10883100B2 (en) * 2011-03-29 2021-01-05 Phynexus, Inc Devices and methods for plasmid purification
US11274292B2 (en) 2011-03-29 2022-03-15 Phynexus, Inc. Devices and methods for plasmid purification
CN102212466B (zh) * 2011-04-11 2013-08-28 中国人民解放军军事医学科学院放射与辐射医学研究所 制备质粒dna的碱裂解系统及组合系统
EP2731628B1 (en) 2011-07-11 2019-09-04 Inovio Pharmaceuticals, Inc. Dna vaccine against lassa virus
US9556427B2 (en) * 2013-02-27 2017-01-31 Syngenta Participations Ag Methods and compositions for preparation of nucleic acids
EP2968607B1 (en) 2013-03-15 2019-07-24 The Trustees Of The University Of Pennsylvania Cancer vaccines and methods of treatment using the same
KR101718045B1 (ko) * 2015-09-07 2017-03-20 엘지전자 주식회사 스크롤 압축기
CN108883312B (zh) 2016-02-05 2024-04-09 因诺维奥制药公司 癌症疫苗和使用其的治疗方法
HUE061198T2 (hu) 2017-12-13 2023-05-28 Inovio Pharmaceuticals Inc A PRAME-t célzó rákvakcinák és alkalmazásaik
AU2018383662C1 (en) 2017-12-13 2023-02-09 Inovio Pharmaceuticals, Inc. Cancer vaccines targeting MUC16 and uses thereof
JP7352547B2 (ja) 2017-12-13 2023-09-28 イノビオ ファーマシューティカルズ,インコーポレイティド メソセリンを標的とするがんワクチンおよびその使用
TWI814812B (zh) * 2018-05-02 2023-09-11 美商里珍納龍藥品有限公司 用於評估生化過濾器的適合性的方法
AU2019278943A1 (en) * 2018-05-31 2021-01-21 Vgxi Inc. Lysis coil apparatus and uses thereof for isolation and purification of polynucleotides
EP3594338A1 (en) * 2018-07-12 2020-01-15 Kaneka Eurogentec SA Method and apparatus for the purification of extra-chromosomal nucleic acid sequences
CN116855359A (zh) * 2023-07-11 2023-10-10 江苏谱新生物医药有限公司 一种质粒碱裂解的系统和方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197553B1 (en) * 1994-07-15 2001-03-06 Merck & Co., Inc. Method for large scale plasmid purification
AR003122A1 (es) * 1995-05-19 1998-07-08 Merck & Co Inc Un proceso para aislacion y purificacion de plasmidos en fermentadores de gran escala y el adn aislado y purificado obtenido mediante dicho proceso.
PT1242442E (pt) * 1999-12-22 2007-11-08 Merck & Co Inc Processo para a purificação de adn de lasmídeo adaptável a outra escala
PT102491B (pt) * 2000-07-10 2003-02-28 Inst Superior Tecnico Processo para producao e purificacao de dna plasmidico
US20030197936A1 (en) * 2002-04-18 2003-10-23 The Board Of Trustees Of The Leland Stanford Junior University Tunable polarization mode dispersion compensation using multi-layered reflector
GB0210899D0 (en) * 2002-05-13 2002-06-19 Aston Photonic Tech Ltd Dispersion compensator
CA2498518A1 (en) * 2002-09-13 2004-03-25 Valentis, Inc. Apparatus and method for preparative scale purification of nucleic acids
EP1462519A1 (en) * 2003-03-24 2004-09-29 Boehringer Ingelheim Austria GmbH Method and devices for producing biomolecules
ES2748130T3 (es) * 2003-05-30 2020-03-13 Vgxi Inc Dispositivos y métodos para la producción de un biomaterial
US7221827B2 (en) * 2003-09-08 2007-05-22 Aegis Semiconductor, Inc. Tunable dispersion compensator
BRPI0413907A (pt) * 2003-09-17 2006-10-24 Centelion método de preparação de plasmìdeo dna de grau farmacêutico
WO2005100542A1 (en) * 2004-04-19 2005-10-27 Centelion Method for purifying plasmid dna
SE0400490D0 (sv) * 2004-02-26 2004-02-26 Amersham Biosciences Ab Plasmid purification
CN100439497C (zh) * 2006-05-26 2008-12-03 吉林大学 一种适用于大规模生产质粒dna的纯化方法

Also Published As

Publication number Publication date
US20230002720A1 (en) 2023-01-05
US20090004716A1 (en) 2009-01-01
CN105567672A (zh) 2016-05-11
EP2153260A1 (en) 2010-02-17
CA2685069A1 (en) 2008-12-04
CA2685069C (en) 2019-01-15
ES2622418T3 (es) 2017-07-06
KR101497728B1 (ko) 2015-03-03
HRP20170233T1 (hr) 2017-06-02
US20200017819A1 (en) 2020-01-16
JP5793726B2 (ja) 2015-10-14
WO2008148010A8 (en) 2010-02-18
JP2010527617A (ja) 2010-08-19
US11453855B2 (en) 2022-09-27
WO2008148010A1 (en) 2008-12-04
AU2008256681B2 (en) 2014-07-31
CN101702938A (zh) 2010-05-05
WO2008148010A9 (en) 2013-10-24
KR20100017884A (ko) 2010-02-16
EP2153260B1 (en) 2017-01-25
AU2008256681A1 (en) 2008-12-04

Similar Documents

Publication Publication Date Title
PT2153260T (pt) Composição que compreende uma alta concentração de moléculas biologicamente ativas e processos de preparação da mesma
IL243534B (en) Methods for the preparation of biologically active compounds in the form of nanoparticles
EP2185701A4 (en) COMPOSITIONS AND METHODS FOR ENHANCING THE PRODUCTION OF RECOMBINANT POLYPEPTIDES
IL225198A (en) Aminotetrahydropyrenic Compounds, Pharmaceutical Preparations Containing Them and Their Use in the Treatment of Diabetes
DE102005001078A8 (de) Glaspulver, insbesondere biologisch aktives Glaspulver und Verfahren zur Herstellung von Glaspulver, insbesondere biologisch aktivem Glaspulver
GB2434604B (en) Porous composites containing hydrocarbon-soluble well treatment agents and methods for using the same
EP1971288A4 (en) MICRONIZED DEVICE FOR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES AND METHOD OF USE
HK1200033A1 (en) Oxygen scavenging molecules, articles containing same, and methods of their use
PT1902706T (pt) Composições farmacêuticas estáveis de tetraciclinas em solução, seu método de obtenção e suas utilizações
EP2406379A4 (en) COMPOSITIONS AND METHODS FOR RELEASING BIOLOGICALLY ACTIVE RNA
EP2271657A4 (en) GEL MICROTOKE COMPOSITION AND METHOD FOR THE APPLICATION
PL2012765T5 (pl) Płynne kompozycje zawierające fenylefrynę i acetaminofen oraz ich zastosowanie do leczenia chorób układu oddechowego
EP2286250A4 (en) POROUS AND NON-POROUS NANOSTRUCTURES AND THEIR APPLICATION
EP1947176A4 (en) METHOD FOR STABILIZING BIOLOGICAL MOLECULE AND COMPOSITION THEREOF
ZA200810741B (en) Methodes for the preparation of biologically active compounds in nanoparticulate form
HRP20141139T1 (en) Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
BRPI0720323A2 (pt) composto, método de tratamento, composição farmacêutica e uso do composto
FI20070395A (fi) Fotokatalyyttisesti aktiivinen koostumus ja menetelmä sen valmistamiseksi
ZA201001825B (en) Increasing the in vivo biological activity of biologically active compounds
EP2361907A4 (en) THE FIVE CRYSTALLINE FORMS OF NICOUSAMIDE, PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
GB0617875D0 (en) Controlled delivery creatine formulations and method of using the same
EP2066171A4 (en) ADMINISTERING A TREATMENT SUBSTANCE TO POROUS ELEMENTS
IL206337A0 (en) Composition of aqueous buffer solution for the treatment of cellular environment and ion channels and methods for using same
EP1962882A4 (en) COMPOSITIONS AND METHOD FOR TREATING DIABETES
EP2275437A4 (en) POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING THE POLYPEPTIDE