PT2082226E - Análise sequencial de amostras biológicas - Google Patents
Análise sequencial de amostras biológicas Download PDFInfo
- Publication number
- PT2082226E PT2082226E PT07871481T PT07871481T PT2082226E PT 2082226 E PT2082226 E PT 2082226E PT 07871481 T PT07871481 T PT 07871481T PT 07871481 T PT07871481 T PT 07871481T PT 2082226 E PT2082226 E PT 2082226E
- Authority
- PT
- Portugal
- Prior art keywords
- sample
- fluorescent probe
- binding
- detecting
- probe
- Prior art date
Links
- 239000012472 biological sample Substances 0.000 title abstract 3
- 238000012882 sequential analysis Methods 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 7
- 239000007850 fluorescent dye Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 239000007800 oxidant agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/560,599 US7629125B2 (en) | 2006-11-16 | 2006-11-16 | Sequential analysis of biological samples |
| US11/864,085 US7741045B2 (en) | 2006-11-16 | 2007-09-28 | Sequential analysis of biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2082226E true PT2082226E (pt) | 2011-10-31 |
Family
ID=39313177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT07871481T PT2082226E (pt) | 2006-11-16 | 2007-11-15 | Análise sequencial de amostras biológicas |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7741045B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2381257B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5149303B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE520026T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007323794B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2669092C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2082226T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2459725T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2082226T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2082226E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008064067A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (77)
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| US8131476B2 (en) * | 2006-08-07 | 2012-03-06 | General Electric Company | System and method for co-registering multi-channel images of a tissue micro array |
| US20080032321A1 (en) * | 2006-08-07 | 2008-02-07 | General Electric Company | System and methods for analyzing images of tissue samples |
| US8060348B2 (en) * | 2006-08-07 | 2011-11-15 | General Electric Company | Systems for analyzing tissue samples |
| US7629125B2 (en) * | 2006-11-16 | 2009-12-08 | General Electric Company | Sequential analysis of biological samples |
| US20100279272A1 (en) * | 2008-02-13 | 2010-11-04 | Michael Craig Burrell | Multiplexed analysis methods using sers-active nanoparticles |
| EP2110076A1 (en) * | 2008-02-19 | 2009-10-21 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Method and device for near-field dual-wave modality imaging |
| US9572497B2 (en) | 2008-07-25 | 2017-02-21 | Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Quantitative multi-spectral opto-acoustic tomography (MSOT) of tissue biomarkers |
| WO2011000389A1 (en) | 2009-06-29 | 2011-01-06 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Thermoacoustic imaging with quantitative extraction of absorption map |
| US10292593B2 (en) | 2009-07-27 | 2019-05-21 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Imaging device and method for optoacoustic imaging of small animals |
| US8269827B2 (en) * | 2009-09-29 | 2012-09-18 | General Electric Company | System and methods for mapping fluorescent images into a bright field color space |
| US9677125B2 (en) | 2009-10-21 | 2017-06-13 | General Electric Company | Detection of plurality of targets in biological samples |
| WO2012058638A2 (en) | 2010-10-29 | 2012-05-03 | President And Fellows Of Harvard College | Nucleic acid nanostructure barcode probes |
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| US8639013B2 (en) | 2011-08-17 | 2014-01-28 | General Electric Company | System and methods for generating a brightfield image using fluorescent images |
| US8568991B2 (en) | 2011-12-23 | 2013-10-29 | General Electric Company | Photoactivated chemical bleaching of dyes |
| US9176032B2 (en) | 2011-12-23 | 2015-11-03 | General Electric Company | Methods of analyzing an H and E stained biological sample |
| EP2825882A1 (en) * | 2012-03-16 | 2015-01-21 | UMC Utrecht Holding B.V. | Biomarkers for adverse cardiac remodeling |
| CA2867144C (en) | 2012-03-27 | 2019-07-02 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
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| US20140024024A1 (en) * | 2012-07-17 | 2014-01-23 | General Electric Company | Methods of detecting dna, rna and protein in biological samples |
| EP2742854B1 (en) | 2012-12-11 | 2021-03-10 | iThera Medical GmbH | Handheld device and method for tomographic optoacoustic imaging of an object |
| EP2754388B1 (en) | 2013-01-15 | 2020-09-09 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH | System and method for quality-enhanced high-rate optoacoustic imaging of an object |
| EP2965087B1 (en) | 2013-03-06 | 2018-10-17 | General Electric Company | Methods of analyzing an h&e stained biological sample |
| CN105247069A (zh) * | 2013-06-04 | 2016-01-13 | 豪夫迈·罗氏有限公司 | 用于fret的新化合物及与其相关的方法 |
| KR20160039229A (ko) | 2013-07-30 | 2016-04-08 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 정량적 dna-기반 영상화 및 초해상도 영상화 |
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| BR112016018314A2 (pt) * | 2014-03-11 | 2017-10-17 | Harvard College | formação de imagem de alto desempenho e altamente multiplexada com sondas programáveis de ácido nucleico |
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| US9933431B2 (en) | 2014-08-22 | 2018-04-03 | Arizona Board Of Regents On Behalf Of Arizona State University | System and method for iterative detection of biological molecules |
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| AU2016295158B2 (en) | 2015-07-17 | 2021-02-25 | Bruker Spatial Biology, Inc. | Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue |
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| EP3894583A4 (en) | 2018-12-13 | 2022-11-09 | President and Fellows of Harvard College | AMPLIFICATION METHODS AND SYSTEMS FOR MERFISH AND OTHER APPLICATIONS |
| CN113574386A (zh) | 2019-01-03 | 2021-10-29 | 国家医疗保健研究所 | 用于增强癌症患者的cd8+t细胞依赖性免疫应答的方法和药物组合物 |
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| CA3157889A1 (en) | 2019-10-17 | 2021-04-22 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for diagnosing nasal intestinal type adenocarcinomas |
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| EP4172621A1 (en) | 2020-06-30 | 2023-05-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies |
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| WO2023143179A1 (zh) * | 2022-01-28 | 2023-08-03 | 南京大学 | 一种对抗原样本的处理方法和应用 |
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| CA3245129A1 (en) | 2022-03-17 | 2023-09-21 | Universite Paris Cite | METHODS FOR PREDICTING RESPONSE TO IMMUNOTHERAPEUTIC TREATMENT IN A CANCER PATIENT |
| US20250231193A1 (en) | 2022-04-11 | 2025-07-17 | Institut National de la Santé et de la Recherche Médicale | Methods for the diagnosis and treatment of t-cell malignancies |
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| JP2025526336A (ja) | 2022-07-22 | 2025-08-13 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | T細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのgarp |
| WO2024023283A1 (en) | 2022-07-29 | 2024-02-01 | Institut National de la Santé et de la Recherche Médicale | Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas |
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-
2007
- 2007-09-28 US US11/864,085 patent/US7741045B2/en active Active
- 2007-11-15 WO PCT/US2007/084800 patent/WO2008064067A2/en not_active Ceased
- 2007-11-15 DK DK07871481.3T patent/DK2082226T3/da active
- 2007-11-15 PT PT07871481T patent/PT2082226E/pt unknown
- 2007-11-15 ES ES11175116.0T patent/ES2459725T3/es active Active
- 2007-11-15 AT AT07871481T patent/ATE520026T1/de active
- 2007-11-15 CA CA2669092A patent/CA2669092C/en active Active
- 2007-11-15 AU AU2007323794A patent/AU2007323794B2/en not_active Ceased
- 2007-11-15 EP EP11175116.0A patent/EP2381257B1/en active Active
- 2007-11-15 PL PL07871481T patent/PL2082226T3/pl unknown
- 2007-11-15 EP EP07871481A patent/EP2082226B1/en active Active
- 2007-11-15 JP JP2009537360A patent/JP5149303B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2381257B1 (en) | 2014-03-26 |
| ATE520026T1 (de) | 2011-08-15 |
| DK2082226T3 (da) | 2011-11-14 |
| WO2008064067A2 (en) | 2008-05-29 |
| US7741045B2 (en) | 2010-06-22 |
| AU2007323794B2 (en) | 2013-08-22 |
| US20080118934A1 (en) | 2008-05-22 |
| EP2381257A1 (en) | 2011-10-26 |
| EP2082226B1 (en) | 2011-08-10 |
| PL2082226T3 (pl) | 2012-01-31 |
| JP2010510493A (ja) | 2010-04-02 |
| WO2008064067A3 (en) | 2008-07-10 |
| EP2082226A2 (en) | 2009-07-29 |
| JP5149303B2 (ja) | 2013-02-20 |
| CA2669092C (en) | 2016-07-26 |
| AU2007323794A1 (en) | 2008-05-29 |
| ES2459725T3 (es) | 2014-05-12 |
| CA2669092A1 (en) | 2008-05-29 |
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