PT1979375E - Aglomerados de genes biossintéticos lantibióticos de a. garbadinensis e a. liguriae - Google Patents
Aglomerados de genes biossintéticos lantibióticos de a. garbadinensis e a. liguriae Download PDFInfo
- Publication number
- PT1979375E PT1979375E PT07704921T PT07704921T PT1979375E PT 1979375 E PT1979375 E PT 1979375E PT 07704921 T PT07704921 T PT 07704921T PT 07704921 T PT07704921 T PT 07704921T PT 1979375 E PT1979375 E PT 1979375E
- Authority
- PT
- Portugal
- Prior art keywords
- seq
- actagardine
- compound
- polypeptide
- deoxyactagardine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/045—Actinoplanes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0600928.6A GB0600928D0 (en) | 2006-01-17 | 2006-01-17 | Improvements relating to lantibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1979375E true PT1979375E (pt) | 2012-03-06 |
Family
ID=35998187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT07704921T PT1979375E (pt) | 2006-01-17 | 2007-01-17 | Aglomerados de genes biossintéticos lantibióticos de a. garbadinensis e a. liguriae |
Country Status (20)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0600928D0 (en) | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
| GB0714029D0 (en) * | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
| GB0714030D0 (en) * | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
| GB0900599D0 (en) | 2009-01-14 | 2009-02-18 | Novacta Biosystems Ltd | Treatment |
| TWI453029B (zh) * | 2009-01-14 | 2014-09-21 | Novacta Biosystems Ltd | 去氧艾克特卡丁b(deoxyactagardine b), 包含其之醫藥組合物及其製造方法 |
| BRPI1007884A2 (pt) * | 2009-02-04 | 2016-09-06 | Novacta Biosystems Ltd | derivados de actagardina |
| GB201001688D0 (en) | 2010-02-02 | 2010-03-17 | Novacta Biosystems Ltd | Compounds |
| WO2011095768A1 (en) | 2010-02-02 | 2011-08-11 | Novacta Biosystems Limited | Lantibiotic salts |
| EA201291461A1 (ru) * | 2010-07-14 | 2013-08-30 | Новакта Биосистемс Лимитед | Состав, содержащий лантибиотик типа b |
| GB201013507D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Compounds |
| GB201013509D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Compounds |
| GB201013508D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Compounds |
| GB201013513D0 (en) * | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Formulations |
| US9975930B2 (en) | 2012-11-30 | 2018-05-22 | Naicons S.R.L. | Lantibiotic derivatives and process for their preparation |
| CN103483433B (zh) * | 2013-09-10 | 2015-05-27 | 中国科学院微生物研究所 | 一种新型高效的羊毛硫细菌素cerecidin及其应用 |
| CN106188253B (zh) * | 2016-08-26 | 2020-08-18 | 上海交通大学 | 抗菌肽Lexapeptide及其制备方法和用途 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3710795A (en) | 1970-09-29 | 1973-01-16 | Alza Corp | Drug-delivery device with stretched, rate-controlling membrane |
| GB8507528D0 (en) | 1985-03-22 | 1985-05-01 | Lepetit Spa | Basis monocarboxyamide derivatives |
| US5304540A (en) | 1988-06-22 | 1994-04-19 | Applied Microbiology, Inc. | Pharmaceutical bacteriocin compositions and methods for using the same |
| IN167138B (US07794700-20100914-C00152.png) | 1988-08-17 | 1990-09-01 | Hoechst India | |
| GB8926639D0 (en) | 1989-11-24 | 1990-01-17 | Agricultural & Food Res | Delayed release formulations |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| IT1260505B (it) | 1992-06-01 | 1996-04-09 | Poli Ind Chimica Spa | Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon |
| IL107887A (en) | 1992-12-08 | 2003-07-06 | Ambi Inc | Stabilized lanthionine containing bacteriocin compositions |
| US5512269A (en) | 1993-06-09 | 1996-04-30 | Burroughs Wellcome, Co. | Method of treating retained pulmonary secretions |
| PT700998E (pt) | 1994-09-12 | 2004-03-31 | Aventis Pharma Gmbh | Mersacidina recombinante e metodo para a sua producao |
| SK285563B6 (sk) | 1995-06-23 | 2007-03-01 | Ambi, Inc. | Použitie lanthocinu na výrobu liečiva na liečenieinfekcie |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| US5985823A (en) | 1997-06-09 | 1999-11-16 | Ambi Inc. | Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon |
| US5958873A (en) | 1997-06-09 | 1999-09-28 | University Of Cincinnati | Oral formulation for treatment of bacteria-induced diseases of the colon |
| DE19745583A1 (de) * | 1997-10-15 | 1999-04-22 | Hoechst Marion Roussel De Gmbh | Neues Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung derselben |
| US6569830B1 (en) | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
| CA2413330A1 (en) | 2000-06-28 | 2002-01-03 | Smithkline Beecham P.L.C. | Wet milling process |
| GB0110432D0 (en) * | 2001-04-27 | 2001-06-20 | Plant Bioscience Ltd | Lantibiotic production |
| WO2002103010A1 (en) | 2001-06-14 | 2002-12-27 | Plant Bioscience Limited | Methods and materials for targeted gene disruption in actinomycete bacteria |
| US6861236B2 (en) | 2002-05-24 | 2005-03-01 | Applied Nanosystems B.V. | Export and modification of (poly)peptides in the lantibiotic way |
| EP1558746A4 (en) | 2002-10-10 | 2006-11-22 | Molichem Medicines Inc | DURAMYCIN-CODING NUCLEIC ACIDS |
| US7351687B2 (en) | 2003-07-18 | 2008-04-01 | Vicuron Pharmaceuticals, Inc. | Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof |
| ATE356143T1 (de) | 2003-07-18 | 2007-03-15 | Vicuron Pharm Inc | Antibiotikum 107891, dessen faktoren a1 und a2, pharmazeutisch unbedenkliche salze und zusammensetzungen, und anwendung davon |
| EP1720910A4 (en) * | 2004-02-17 | 2007-11-21 | Cancervax Corp | METHOD AND COMPOSITION FOR INHIBITING ANGIOGENESIS |
| GB0406870D0 (en) | 2004-03-26 | 2004-04-28 | Novacta Biosystems Ltd | Improvements relating to the production of lantibiotics |
| EP1928900A1 (en) | 2005-09-27 | 2008-06-11 | Novacta Biosystems Limited | Variants of the lantibiotic mersacidin and their use |
| GB0600928D0 (en) | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
| KR20120038021A (ko) | 2006-10-27 | 2012-04-20 | 화이자 프로덕츠 인코포레이티드 | 하이드록시프로필 메틸 셀룰로스 경질 캡슐 및 이의 제조 방법 |
| WO2008151434A1 (en) | 2007-06-12 | 2008-12-18 | The University Of British Columbia | Small cationic antimicrobial peptides |
| GB0714029D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
| GB0714030D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
| EP2367845A1 (en) | 2008-11-24 | 2011-09-28 | Sentinella Pharmaceuticals, Inc. ("Sentinella") | Lantibiotic carboxyamide derivatives with enhanced antibacterial activity |
| GB0900599D0 (en) | 2009-01-14 | 2009-02-18 | Novacta Biosystems Ltd | Treatment |
| TWI453029B (zh) | 2009-01-14 | 2014-09-21 | Novacta Biosystems Ltd | 去氧艾克特卡丁b(deoxyactagardine b), 包含其之醫藥組合物及其製造方法 |
| BRPI1007884A2 (pt) | 2009-02-04 | 2016-09-06 | Novacta Biosystems Ltd | derivados de actagardina |
| EP2216937A1 (en) | 2009-02-10 | 2010-08-11 | Alcatel Lucent | Alarm notification between customer premises equipment and a remote management server |
-
2006
- 2006-01-17 GB GBGB0600928.6A patent/GB0600928D0/en not_active Ceased
-
2007
- 2007-01-17 BR BRPI0706525-6A patent/BRPI0706525A2/pt active Search and Examination
- 2007-01-17 AU AU2007206769A patent/AU2007206769B2/en not_active Ceased
- 2007-01-17 ES ES07704921T patent/ES2378090T3/es active Active
- 2007-01-17 PT PT07704921T patent/PT1979375E/pt unknown
- 2007-01-17 US US12/161,221 patent/US7989416B2/en not_active Ceased
- 2007-01-17 NZ NZ569486A patent/NZ569486A/en not_active IP Right Cessation
- 2007-01-17 US US13/705,010 patent/USRE45003E1/en not_active Expired - Fee Related
- 2007-01-17 CA CA002637315A patent/CA2637315A1/en not_active Abandoned
- 2007-01-17 AT AT07704921T patent/ATE534659T1/de active
- 2007-01-17 WO PCT/GB2007/000138 patent/WO2007083112A2/en active Application Filing
- 2007-01-17 KR KR1020087018136A patent/KR101573536B1/ko not_active IP Right Cessation
- 2007-01-17 PL PL07704921T patent/PL1979375T3/pl unknown
- 2007-01-17 DK DK07704921.1T patent/DK1979375T3/da active
- 2007-01-17 MX MX2008009047A patent/MX2008009047A/es active IP Right Grant
- 2007-01-17 EP EP07704921A patent/EP1979375B9/en not_active Not-in-force
- 2007-01-17 EP EP20100000424 patent/EP2189472A1/en not_active Withdrawn
- 2007-01-17 CN CN2007800067480A patent/CN101389641B/zh not_active Expired - Fee Related
- 2007-01-17 SI SI200730846T patent/SI1979375T1/sl unknown
- 2007-01-17 JP JP2008550839A patent/JP5219837B2/ja not_active Expired - Fee Related
-
2008
- 2008-06-25 IL IL192446A patent/IL192446A0/en unknown
-
2011
- 2011-06-10 US US13/157,454 patent/US8465947B2/en not_active Expired - Fee Related
-
2012
- 2012-02-17 CY CY20121100166T patent/CY1112559T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1979375B9 (en) | 2012-05-09 |
| US8465947B2 (en) | 2013-06-18 |
| US7989416B2 (en) | 2011-08-02 |
| DK1979375T3 (da) | 2012-03-19 |
| USRE45003E1 (en) | 2014-07-08 |
| CN101389641A (zh) | 2009-03-18 |
| CY1112559T1 (el) | 2016-02-10 |
| ATE534659T1 (de) | 2011-12-15 |
| GB0600928D0 (en) | 2006-02-22 |
| US20110306091A1 (en) | 2011-12-15 |
| AU2007206769A1 (en) | 2007-07-26 |
| NZ569486A (en) | 2011-07-29 |
| WO2007083112A3 (en) | 2008-05-08 |
| KR20080086517A (ko) | 2008-09-25 |
| EP1979375A2 (en) | 2008-10-15 |
| US20100048459A1 (en) | 2010-02-25 |
| EP2189472A1 (en) | 2010-05-26 |
| WO2007083112A2 (en) | 2007-07-26 |
| AU2007206769B2 (en) | 2013-06-20 |
| JP2009523777A (ja) | 2009-06-25 |
| CA2637315A1 (en) | 2007-07-26 |
| MX2008009047A (es) | 2008-12-18 |
| CN101389641B (zh) | 2013-06-05 |
| BRPI0706525A2 (pt) | 2011-03-29 |
| PL1979375T3 (pl) | 2012-04-30 |
| KR101573536B1 (ko) | 2015-12-11 |
| SI1979375T1 (sl) | 2012-03-30 |
| ES2378090T3 (es) | 2012-04-04 |
| EP1979375B1 (en) | 2011-11-23 |
| IL192446A0 (en) | 2008-12-29 |
| JP5219837B2 (ja) | 2013-06-26 |
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