PT1781631E - Derivados de diarilmetilpiperazina, suas preparações e suas utilizações - Google Patents
Derivados de diarilmetilpiperazina, suas preparações e suas utilizações Download PDFInfo
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- PT1781631E PT1781631E PT05762524T PT05762524T PT1781631E PT 1781631 E PT1781631 E PT 1781631E PT 05762524 T PT05762524 T PT 05762524T PT 05762524 T PT05762524 T PT 05762524T PT 1781631 E PT1781631 E PT 1781631E
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- DKJCUVXSBOMWAV-PCWWUVHHSA-N naltrindole Chemical compound N1([C@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CC2=C3[CH]C=CC=C3N=C25)O)CC1)O)CC1CC1 DKJCUVXSBOMWAV-PCWWUVHHSA-N 0.000 description 1
- 229960004927 neomycin Drugs 0.000 description 1
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- 239000012299 nitrogen atmosphere Substances 0.000 description 1
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- RGCLLPNLLBQHPF-HJWRWDBZSA-N phosphamidon Chemical compound CCN(CC)C(=O)C(\Cl)=C(/C)OP(=O)(OC)OC RGCLLPNLLBQHPF-HJWRWDBZSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
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- 229920001223 polyethylene glycol Polymers 0.000 description 1
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- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
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- 238000002791 soaking Methods 0.000 description 1
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- 239000007909 solid dosage form Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401968A SE0401968D0 (sv) | 2004-08-02 | 2004-08-02 | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
| US60236304P | 2004-08-18 | 2004-08-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1781631E true PT1781631E (pt) | 2012-05-07 |
Family
ID=32906880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05762524T PT1781631E (pt) | 2004-08-02 | 2005-07-27 | Derivados de diarilmetilpiperazina, suas preparações e suas utilizações |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20070249619A1 (enExample) |
| EP (1) | EP1781631B1 (enExample) |
| JP (1) | JP5006785B2 (enExample) |
| CN (1) | CN1993338B (enExample) |
| AR (1) | AR050260A1 (enExample) |
| AT (1) | ATE542806T1 (enExample) |
| AU (1) | AU2005267929B2 (enExample) |
| BR (1) | BRPI0514014A (enExample) |
| CA (1) | CA2576067C (enExample) |
| ES (1) | ES2379364T3 (enExample) |
| NZ (1) | NZ553539A (enExample) |
| PL (1) | PL1781631T3 (enExample) |
| PT (1) | PT1781631E (enExample) |
| RS (1) | RS52315B (enExample) |
| RU (1) | RU2404172C2 (enExample) |
| SE (1) | SE0401968D0 (enExample) |
| SG (1) | SG155181A1 (enExample) |
| SI (1) | SI1781631T1 (enExample) |
| TW (1) | TWI370124B (enExample) |
| UA (1) | UA87146C2 (enExample) |
| WO (1) | WO2006014133A1 (enExample) |
| ZA (1) | ZA200700680B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ539828A (en) | 2001-05-18 | 2007-01-26 | Astrazeneca Ab | 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
| SE0203303D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203302D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203300D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0401968D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
| KR101234421B1 (ko) * | 2004-08-02 | 2013-02-18 | 아스트라제네카 아베 | 디아릴메틸 피페라진 유도체, 이의 제조 방법 및 용도 |
| WO2009074487A1 (en) | 2007-12-11 | 2009-06-18 | F. Hoffmann-La Roche Ag | Inhibitors of stearoyl-coa desaturase |
| EA201001644A1 (ru) * | 2008-05-20 | 2011-06-30 | Астразенека Аб | Способ лечения тревожного большого депрессивного расстройства |
| US8314250B2 (en) | 2009-11-24 | 2012-11-20 | Hoffmann-La Roche Inc. | Sultam derivatives |
| US20110207745A1 (en) * | 2009-11-25 | 2011-08-25 | Astrazeneca Ab | Solid forms of 4--n,n-diethylbenzamide, compositions thereof, and uses therewith |
| US9073881B2 (en) | 2011-09-23 | 2015-07-07 | Hoffmann-La Roche Inc. | Benzoic acid derivatives |
| CN121914037B (zh) * | 2026-03-25 | 2026-07-24 | 福安药业集团宁波天衡制药有限公司 | 盐酸左西替利嗪中间体的制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH585209A5 (enExample) * | 1973-06-29 | 1977-02-28 | Cermol Sa | |
| US4568649A (en) * | 1983-02-22 | 1986-02-04 | Immunex Corporation | Immediate ligand detection assay |
| SE8500573D0 (sv) * | 1985-02-08 | 1985-02-08 | Ferrosan Ab | Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain |
| US5840896A (en) * | 1989-11-22 | 1998-11-24 | Janssen Pharmaceutica, N.V. | Method of preventing or limiting reperfusion damage |
| US5681830A (en) * | 1992-02-03 | 1997-10-28 | Delta Pharmaceuticals, Inc. | Opioid compounds |
| US5807858A (en) * | 1996-06-05 | 1998-09-15 | Delta Pharmaceutical, Inc. | Compositions and methods for reducing respiratory depression |
| US5574159A (en) * | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| GB9202238D0 (en) * | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| WO1995004051A1 (en) * | 1993-07-30 | 1995-02-09 | The Wellcome Foundation Limited | Piperazine compounds used in therapy |
| SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| SE9904674D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE9904673D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE0001209D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0101766D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| NZ539828A (en) * | 2001-05-18 | 2007-01-26 | Astrazeneca Ab | 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
| JP4892654B2 (ja) * | 2001-10-29 | 2012-03-07 | マウント クック ファーマ，インコーポレーテッド | デルタレセプターアゴニスト化合物によるうつ病の治療方法 |
| US8476280B2 (en) * | 2002-05-09 | 2013-07-02 | Versi Group, Llc | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists |
| SE0203303D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203302D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203300D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0400027D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
| SE0401968D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
-
2004
- 2004-08-02 SE SE0401968A patent/SE0401968D0/xx unknown
-
2005
- 2005-07-20 AR ARP050102998A patent/AR050260A1/es not_active Application Discontinuation
- 2005-07-21 TW TW094124625A patent/TWI370124B/zh not_active IP Right Cessation
- 2005-07-27 SI SI200531515T patent/SI1781631T1/sl unknown
- 2005-07-27 WO PCT/SE2005/001186 patent/WO2006014133A1/en not_active Ceased
- 2005-07-27 RS RS20120167A patent/RS52315B/sr unknown
- 2005-07-27 ES ES05762524T patent/ES2379364T3/es not_active Expired - Lifetime
- 2005-07-27 UA UAA200700154A patent/UA87146C2/ru unknown
- 2005-07-27 CN CN2005800262747A patent/CN1993338B/zh not_active Expired - Fee Related
- 2005-07-27 SG SG200905179-8A patent/SG155181A1/en unknown
- 2005-07-27 US US11/572,948 patent/US20070249619A1/en not_active Abandoned
- 2005-07-27 RU RU2007101522/04A patent/RU2404172C2/ru not_active IP Right Cessation
- 2005-07-27 JP JP2007524765A patent/JP5006785B2/ja not_active Expired - Fee Related
- 2005-07-27 CA CA2576067A patent/CA2576067C/en not_active Expired - Fee Related
- 2005-07-27 PT PT05762524T patent/PT1781631E/pt unknown
- 2005-07-27 AU AU2005267929A patent/AU2005267929B2/en not_active Ceased
- 2005-07-27 BR BRPI0514014-5A patent/BRPI0514014A/pt not_active IP Right Cessation
- 2005-07-27 PL PL05762524T patent/PL1781631T3/pl unknown
- 2005-07-27 EP EP05762524A patent/EP1781631B1/en not_active Expired - Lifetime
- 2005-07-27 NZ NZ553539A patent/NZ553539A/en not_active IP Right Cessation
- 2005-07-27 AT AT05762524T patent/ATE542806T1/de active
- 2005-10-05 US US11/243,623 patent/US20060030569A1/en not_active Abandoned
-
2007
- 2007-01-24 ZA ZA200700680A patent/ZA200700680B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL1781631T3 (pl) | 2012-07-31 |
| CN1993338B (zh) | 2011-07-06 |
| CN1993338A (zh) | 2007-07-04 |
| CA2576067A1 (en) | 2006-02-09 |
| RU2007101522A (ru) | 2008-09-10 |
| RS52315B (sr) | 2012-12-31 |
| TWI370124B (en) | 2012-08-11 |
| NZ553539A (en) | 2010-09-30 |
| SE0401968D0 (sv) | 2004-08-02 |
| BRPI0514014A (pt) | 2008-05-27 |
| SG155181A1 (en) | 2009-09-30 |
| EP1781631B1 (en) | 2012-01-25 |
| AU2005267929A1 (en) | 2006-02-09 |
| ES2379364T3 (es) | 2012-04-25 |
| AU2005267929B2 (en) | 2010-04-08 |
| US20070249619A1 (en) | 2007-10-25 |
| ATE542806T1 (de) | 2012-02-15 |
| ZA200700680B (en) | 2008-09-25 |
| EP1781631A1 (en) | 2007-05-09 |
| AR050260A1 (es) | 2006-10-11 |
| SI1781631T1 (sl) | 2012-05-31 |
| JP5006785B2 (ja) | 2012-08-22 |
| JP2008508350A (ja) | 2008-03-21 |
| UA87146C2 (ru) | 2009-06-25 |
| WO2006014133A1 (en) | 2006-02-09 |
| US20060030569A1 (en) | 2006-02-09 |
| TW200612930A (en) | 2006-05-01 |
| CA2576067C (en) | 2011-05-03 |
| RU2404172C2 (ru) | 2010-11-20 |
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