PL1781631T3 - Pochodne diarylometylopiperaziny, ich wytwarzanie i ich zastosowania - Google Patents

Pochodne diarylometylopiperaziny, ich wytwarzanie i ich zastosowania

Info

Publication number
PL1781631T3
PL1781631T3 PL05762524T PL05762524T PL1781631T3 PL 1781631 T3 PL1781631 T3 PL 1781631T3 PL 05762524 T PL05762524 T PL 05762524T PL 05762524 T PL05762524 T PL 05762524T PL 1781631 T3 PL1781631 T3 PL 1781631T3
Authority
PL
Poland
Prior art keywords
preparations
piperazine derivatives
diarylmethyl piperazine
diarylmethyl
derivatives
Prior art date
Application number
PL05762524T
Other languages
English (en)
Inventor
William Brown
Andrew Griffin
Thomas Hudzik
Carla Maciag
Gennady Smagin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32906880&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1781631(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PL1781631T3 publication Critical patent/PL1781631T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL05762524T 2004-08-02 2005-07-27 Pochodne diarylometylopiperaziny, ich wytwarzanie i ich zastosowania PL1781631T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0401968A SE0401968D0 (sv) 2004-08-02 2004-08-02 Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
US60236304P 2004-08-18 2004-08-18
PCT/SE2005/001186 WO2006014133A1 (en) 2004-08-02 2005-07-27 Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
EP05762524A EP1781631B1 (en) 2004-08-02 2005-07-27 Diarylmethyl piperazine derivatives, preparations thereof and uses thereof

Publications (1)

Publication Number Publication Date
PL1781631T3 true PL1781631T3 (pl) 2012-07-31

Family

ID=32906880

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05762524T PL1781631T3 (pl) 2004-08-02 2005-07-27 Pochodne diarylometylopiperaziny, ich wytwarzanie i ich zastosowania

Country Status (22)

Country Link
US (2) US20070249619A1 (pl)
EP (1) EP1781631B1 (pl)
JP (1) JP5006785B2 (pl)
CN (1) CN1993338B (pl)
AR (1) AR050260A1 (pl)
AT (1) ATE542806T1 (pl)
AU (1) AU2005267929B2 (pl)
BR (1) BRPI0514014A (pl)
CA (1) CA2576067C (pl)
ES (1) ES2379364T3 (pl)
NZ (1) NZ553539A (pl)
PL (1) PL1781631T3 (pl)
PT (1) PT1781631E (pl)
RS (1) RS52315B (pl)
RU (1) RU2404172C2 (pl)
SE (1) SE0401968D0 (pl)
SG (1) SG155181A1 (pl)
SI (1) SI1781631T1 (pl)
TW (1) TWI370124B (pl)
UA (1) UA87146C2 (pl)
WO (1) WO2006014133A1 (pl)
ZA (1) ZA200700680B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140070A (en) 2001-05-18 2009-11-30 Astrazeneca Ab 4-(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0401968D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
DK1781631T3 (da) 2004-08-02 2012-05-14 Astrazeneca Ab Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf
ES2528471T3 (es) 2007-12-11 2015-02-10 F. Hoffmann-La Roche Ag Inhibidores de la estearoil-CoA-desaturasa
CN102065860A (zh) * 2008-05-20 2011-05-18 阿斯利康(瑞典)有限公司 治疗焦虑性重度抑郁障碍的方法
US8314250B2 (en) 2009-11-24 2012-11-20 Hoffmann-La Roche Inc. Sultam derivatives
US20110207745A1 (en) * 2009-11-25 2011-08-25 Astrazeneca Ab Solid forms of 4--n,n-diethylbenzamide, compositions thereof, and uses therewith
US9073881B2 (en) 2011-09-23 2015-07-07 Hoffmann-La Roche Inc. Benzoic acid derivatives

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH583713A5 (pl) * 1973-06-29 1977-01-14 Cermol Sa
US4568649A (en) * 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
SE8500573D0 (sv) * 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
US5840896A (en) * 1989-11-22 1998-11-24 Janssen Pharmaceutica, N.V. Method of preventing or limiting reperfusion damage
US5681830A (en) * 1992-02-03 1997-10-28 Delta Pharmaceuticals, Inc. Opioid compounds
US5574159A (en) * 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
US5807858A (en) * 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9904674D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0101766D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
MY140070A (en) * 2001-05-18 2009-11-30 Astrazeneca Ab 4-(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
PL371297A1 (pl) * 2001-10-29 2005-06-13 Ardent Pharmaceuticals, Inc. Metoda leczenia depresji związkami będacymi agonistami receptora delta
US8476280B2 (en) * 2002-05-09 2013-07-02 Versi Group, Llc Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
SE0203303D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0400027D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
SE0401968D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof

Also Published As

Publication number Publication date
CA2576067A1 (en) 2006-02-09
NZ553539A (en) 2010-09-30
ZA200700680B (en) 2008-09-25
AU2005267929B2 (en) 2010-04-08
AU2005267929A1 (en) 2006-02-09
JP5006785B2 (ja) 2012-08-22
EP1781631A1 (en) 2007-05-09
EP1781631B1 (en) 2012-01-25
BRPI0514014A (pt) 2008-05-27
CA2576067C (en) 2011-05-03
SG155181A1 (en) 2009-09-30
SE0401968D0 (sv) 2004-08-02
US20070249619A1 (en) 2007-10-25
RU2404172C2 (ru) 2010-11-20
PT1781631E (pt) 2012-05-07
RS52315B (en) 2012-12-31
RU2007101522A (ru) 2008-09-10
US20060030569A1 (en) 2006-02-09
SI1781631T1 (sl) 2012-05-31
CN1993338A (zh) 2007-07-04
ATE542806T1 (de) 2012-02-15
WO2006014133A1 (en) 2006-02-09
ES2379364T3 (es) 2012-04-25
CN1993338B (zh) 2011-07-06
UA87146C2 (ru) 2009-06-25
JP2008508350A (ja) 2008-03-21
AR050260A1 (es) 2006-10-11
TWI370124B (en) 2012-08-11
TW200612930A (en) 2006-05-01

Similar Documents

Publication Publication Date Title
ZA200700680B (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
EP1831240B8 (de) 18-methyl-19-nor-17-pregn-4-en-21,17-carbolactone, sowie diese enthaltende pharmazeutische präparate
IL209494A (en) Formulations of insulin oligomeric monoconogues and their use
EP1828223A4 (en) Novel betulin derivatives, their preparation and their use
IL169366A0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
IL176513A0 (en) Diarylmethyl piperazine derivatives, preparations thereof and used thereof
IL180682A0 (en) N-hydroxamide derivatives, their preparation and use
IL174479A (en) The derivatives of myastrin, pharmaceutical preparations containing them and their uses
IL188928A0 (en) Indol-3-yl-carbonyl-piperidin and piperazin derivatives
IL175817A0 (en) Benzoxazine derivatives and uses thereof
GB2405100B (en) Resuscitators, parts and assemblies
EP1737458A4 (en) R (-) - 11-HYDROXYAPORPHINE DERIVATIVES AND USES THEREOF
PL394604A1 (pl) Pochodna winyloazacykloalkanowa, jej zastosowanie oraz kompozycja farmaceutyczna
IL169360A0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1102815A1 (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
IL180894A0 (en) 1-??-halo-2,2-difluoro-2-deoxy-d-ribofuranose derivatives and processes for the preparation thereof
ZA200704806B (en) Novel betulin derivatives, preparation thereof and use thereof
AU2003300262A1 (en) Phthalimidylazo dyes, processes for the preparation thereof and the use thereof
ZA200605533B (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
ZA200605483B (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
EP1660088A4 (en) PYRIDOMORPHINANES, PYRIDAZINOMORPHINANES AND USE THEREOF
IL176074A0 (en) 1,2,3,4-tetrahydroisoquinoline derivatives, preparations thereof and uses thereof
AU2003299336A1 (en) Diphosphines, preparation and uses thereof
ZA200800523B (en) Indol-3-yl-carbonyl-piperidin and piperazin derivatives
AU2004900719A0 (en) Sperm-Active Preparations and Uses Thereof