ATE542806T1 - Diarylmethylpiperazinderivate, deren herstellung und deren verwendung - Google Patents
Diarylmethylpiperazinderivate, deren herstellung und deren verwendungInfo
- Publication number
- ATE542806T1 ATE542806T1 AT05762524T AT05762524T ATE542806T1 AT E542806 T1 ATE542806 T1 AT E542806T1 AT 05762524 T AT05762524 T AT 05762524T AT 05762524 T AT05762524 T AT 05762524T AT E542806 T1 ATE542806 T1 AT E542806T1
- Authority
- AT
- Austria
- Prior art keywords
- diarylmethylpiperazine
- derivatives
- production
- diarylmethylpiperazine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0401968A SE0401968D0 (sv) | 2004-08-02 | 2004-08-02 | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
US60236304P | 2004-08-18 | 2004-08-18 | |
PCT/SE2005/001186 WO2006014133A1 (en) | 2004-08-02 | 2005-07-27 | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE542806T1 true ATE542806T1 (de) | 2012-02-15 |
Family
ID=32906880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05762524T ATE542806T1 (de) | 2004-08-02 | 2005-07-27 | Diarylmethylpiperazinderivate, deren herstellung und deren verwendung |
Country Status (22)
Country | Link |
---|---|
US (2) | US20070249619A1 (de) |
EP (1) | EP1781631B1 (de) |
JP (1) | JP5006785B2 (de) |
CN (1) | CN1993338B (de) |
AR (1) | AR050260A1 (de) |
AT (1) | ATE542806T1 (de) |
AU (1) | AU2005267929B2 (de) |
BR (1) | BRPI0514014A (de) |
CA (1) | CA2576067C (de) |
ES (1) | ES2379364T3 (de) |
NZ (1) | NZ553539A (de) |
PL (1) | PL1781631T3 (de) |
PT (1) | PT1781631E (de) |
RS (1) | RS52315B (de) |
RU (1) | RU2404172C2 (de) |
SE (1) | SE0401968D0 (de) |
SG (1) | SG155181A1 (de) |
SI (1) | SI1781631T1 (de) |
TW (1) | TWI370124B (de) |
UA (1) | UA87146C2 (de) |
WO (1) | WO2006014133A1 (de) |
ZA (1) | ZA200700680B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4549024B2 (ja) | 2001-05-18 | 2010-09-22 | アストラゼネカ・アクチエボラーグ | 4(フェニル−ピペラジニル−メチル)ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用 |
SE0203302D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203300D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
DK1781631T3 (da) | 2004-08-02 | 2012-05-14 | Astrazeneca Ab | Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf |
SE0401968D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
EP2231619B1 (de) | 2007-12-11 | 2014-11-26 | F. Hoffmann-La Roche AG | Stearoyl-coa-desaturase-hemmer |
EA201001644A1 (ru) * | 2008-05-20 | 2011-06-30 | Астразенека Аб | Способ лечения тревожного большого депрессивного расстройства |
US8314250B2 (en) | 2009-11-24 | 2012-11-20 | Hoffmann-La Roche Inc. | Sultam derivatives |
US20110207745A1 (en) * | 2009-11-25 | 2011-08-25 | Astrazeneca Ab | Solid forms of 4--n,n-diethylbenzamide, compositions thereof, and uses therewith |
US9073881B2 (en) | 2011-09-23 | 2015-07-07 | Hoffmann-La Roche Inc. | Benzoic acid derivatives |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH585209A5 (de) * | 1973-06-29 | 1977-02-28 | Cermol Sa | |
US4568649A (en) * | 1983-02-22 | 1986-02-04 | Immunex Corporation | Immediate ligand detection assay |
SE8500573D0 (sv) * | 1985-02-08 | 1985-02-08 | Ferrosan Ab | Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain |
US5840896A (en) * | 1989-11-22 | 1998-11-24 | Janssen Pharmaceutica, N.V. | Method of preventing or limiting reperfusion damage |
US5574159A (en) * | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
US5681830A (en) * | 1992-02-03 | 1997-10-28 | Delta Pharmaceuticals, Inc. | Opioid compounds |
GB9202238D0 (en) * | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
US5807858A (en) * | 1996-06-05 | 1998-09-15 | Delta Pharmaceutical, Inc. | Compositions and methods for reducing respiratory depression |
SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
SE9904673D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE9904674D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE0001209D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
JP4549024B2 (ja) | 2001-05-18 | 2010-09-22 | アストラゼネカ・アクチエボラーグ | 4(フェニル−ピペラジニル−メチル)ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用 |
SE0101766D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
PL371297A1 (en) * | 2001-10-29 | 2005-06-13 | Ardent Pharmaceuticals, Inc. | Method of treating depression with delta receptor agonist compounds |
US8476280B2 (en) * | 2002-05-09 | 2013-07-02 | Versi Group, Llc | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists |
SE0203300D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203302D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203303D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0400027D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
SE0401968D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
-
2004
- 2004-08-02 SE SE0401968A patent/SE0401968D0/xx unknown
-
2005
- 2005-07-20 AR ARP050102998A patent/AR050260A1/es not_active Application Discontinuation
- 2005-07-21 TW TW094124625A patent/TWI370124B/zh not_active IP Right Cessation
- 2005-07-27 WO PCT/SE2005/001186 patent/WO2006014133A1/en active Application Filing
- 2005-07-27 ES ES05762524T patent/ES2379364T3/es active Active
- 2005-07-27 US US11/572,948 patent/US20070249619A1/en not_active Abandoned
- 2005-07-27 JP JP2007524765A patent/JP5006785B2/ja not_active Expired - Fee Related
- 2005-07-27 CA CA2576067A patent/CA2576067C/en not_active Expired - Fee Related
- 2005-07-27 RU RU2007101522/04A patent/RU2404172C2/ru not_active IP Right Cessation
- 2005-07-27 PL PL05762524T patent/PL1781631T3/pl unknown
- 2005-07-27 NZ NZ553539A patent/NZ553539A/en not_active IP Right Cessation
- 2005-07-27 CN CN2005800262747A patent/CN1993338B/zh not_active Expired - Fee Related
- 2005-07-27 SI SI200531515T patent/SI1781631T1/sl unknown
- 2005-07-27 BR BRPI0514014-5A patent/BRPI0514014A/pt not_active IP Right Cessation
- 2005-07-27 AU AU2005267929A patent/AU2005267929B2/en not_active Ceased
- 2005-07-27 SG SG200905179-8A patent/SG155181A1/en unknown
- 2005-07-27 PT PT05762524T patent/PT1781631E/pt unknown
- 2005-07-27 AT AT05762524T patent/ATE542806T1/de active
- 2005-07-27 EP EP05762524A patent/EP1781631B1/de active Active
- 2005-07-27 UA UAA200700154A patent/UA87146C2/ru unknown
- 2005-07-27 RS RS20120167A patent/RS52315B/en unknown
- 2005-10-05 US US11/243,623 patent/US20060030569A1/en not_active Abandoned
-
2007
- 2007-01-24 ZA ZA200700680A patent/ZA200700680B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SG155181A1 (en) | 2009-09-30 |
SE0401968D0 (sv) | 2004-08-02 |
CN1993338A (zh) | 2007-07-04 |
JP5006785B2 (ja) | 2012-08-22 |
RU2404172C2 (ru) | 2010-11-20 |
EP1781631B1 (de) | 2012-01-25 |
RU2007101522A (ru) | 2008-09-10 |
UA87146C2 (ru) | 2009-06-25 |
AU2005267929A1 (en) | 2006-02-09 |
SI1781631T1 (sl) | 2012-05-31 |
JP2008508350A (ja) | 2008-03-21 |
TW200612930A (en) | 2006-05-01 |
RS52315B (en) | 2012-12-31 |
US20060030569A1 (en) | 2006-02-09 |
CA2576067C (en) | 2011-05-03 |
AR050260A1 (es) | 2006-10-11 |
CA2576067A1 (en) | 2006-02-09 |
US20070249619A1 (en) | 2007-10-25 |
AU2005267929B2 (en) | 2010-04-08 |
CN1993338B (zh) | 2011-07-06 |
TWI370124B (en) | 2012-08-11 |
WO2006014133A1 (en) | 2006-02-09 |
NZ553539A (en) | 2010-09-30 |
PL1781631T3 (pl) | 2012-07-31 |
ES2379364T3 (es) | 2012-04-25 |
ZA200700680B (en) | 2008-09-25 |
BRPI0514014A (pt) | 2008-05-27 |
PT1781631E (pt) | 2012-05-07 |
EP1781631A1 (de) | 2007-05-09 |
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