PT1651248E - Composições farmacêuticas para dose oral compreendendo um agente de administração na forma micronizada - Google Patents

Composições farmacêuticas para dose oral compreendendo um agente de administração na forma micronizada Download PDF

Info

Publication number
PT1651248E
PT1651248E PT04740863T PT04740863T PT1651248E PT 1651248 E PT1651248 E PT 1651248E PT 04740863 T PT04740863 T PT 04740863T PT 04740863 T PT04740863 T PT 04740863T PT 1651248 E PT1651248 E PT 1651248E
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
delivery agent
pharmacologically active
micronized form
orally dosed
Prior art date
Application number
PT04740863T
Other languages
English (en)
Inventor
Simon David Bateman
Alan Edward Royce
Shoufeng Li
Anasuya Ashok Ghosh
Moise Azria
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1651248E publication Critical patent/PT1651248E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Permanent Magnet Type Synchronous Machine (AREA)
PT04740863T 2003-07-11 2004-07-09 Composições farmacêuticas para dose oral compreendendo um agente de administração na forma micronizada PT1651248E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48649503P 2003-07-11 2003-07-11

Publications (1)

Publication Number Publication Date
PT1651248E true PT1651248E (pt) 2009-11-10

Family

ID=34062133

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04740863T PT1651248E (pt) 2003-07-11 2004-07-09 Composições farmacêuticas para dose oral compreendendo um agente de administração na forma micronizada

Country Status (15)

Country Link
US (3) US20070065505A1 (pt)
EP (1) EP1651248B1 (pt)
JP (1) JP5032844B2 (pt)
CN (1) CN1809377B (pt)
AT (1) ATE442158T1 (pt)
AU (1) AU2004255458B2 (pt)
BR (1) BRPI0412458A (pt)
CA (1) CA2529604C (pt)
DE (1) DE602004023093D1 (pt)
ES (1) ES2330638T3 (pt)
HK (1) HK1089950A1 (pt)
MX (1) MXPA06000446A (pt)
PL (1) PL1651248T3 (pt)
PT (1) PT1651248E (pt)
WO (1) WO2005004900A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4959917B2 (ja) * 2001-08-17 2012-06-27 ノバルティス アーゲー 副甲状腺ホルモンフラグメント用経口送達剤としての５−ｃｎａｃ
US20060078622A1 (en) * 2004-08-13 2006-04-13 Emisphere Technologies, Inc. Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
KR20080049128A (ko) 2005-09-19 2008-06-03 에미스페어 테크놀로지스, 인코포레이티드 Ｎ-(5-클로로살리실로일)-8-아미노카프릴산 이나트륨염의결정형
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
ES2426485T3 (es) * 2006-08-31 2013-10-23 Novartis Ag Composiciones farmacéuticas que comprenden hGH para administración oral
AR062925A1 (es) * 2006-09-22 2008-12-17 Novartis Ag Metodo para fabricar tabletas que contienen agentes farmacologicamente activos
PL2215047T3 (pl) * 2007-11-02 2014-05-30 Emisphere Tech Inc Sposób leczenia niedoborów witaminy b12
RU2576511C2 (ru) * 2010-02-24 2016-03-10 Эмисфире Текнолоджис, Инк. Пероральная терапия недостаточности витамина в12
DK2651398T3 (en) 2010-12-16 2018-03-12 Novo Nordisk As Solid compositions comprising a GLP-1 agonist and a salt of N- (8- (2-hydroxybenzyl) amino) caprylic acid
KR101972836B1 (ko) 2011-04-12 2019-04-29 노보 노르디스크 에이/에스 이중 아실화된 ｇｌｐ-1 유도체
CN111494324B (zh) 2012-03-22 2023-05-16 诺和诺德股份有限公司 包含递送剂的组合物及其制备
DK2827845T3 (en) 2012-03-22 2019-04-01 Novo Nordisk As COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF
RS57727B1 (sr) 2012-03-22 2018-12-31 Novo Nordisk As Kompozicije glp-1 peptida i njihovo dobijanje
CN104487056A (zh) 2012-06-20 2015-04-01 诺和诺德A/S（股份有限公司） 包含肽和递送剂的片剂制剂
CN104095828A (zh) * 2014-07-29 2014-10-15 中国药科大学 一种降钙素口服肠溶组合物及其制备方法
WO2019149880A1 (en) 2018-02-02 2019-08-08 Novo Nordisk A/S Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant
EP4326329A1 (en) 2021-04-22 2024-02-28 Civi Biopharma, Inc. Oral delivery of oligonucleotides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US6413546B1 (en) * 1999-03-18 2002-07-02 Indena, S.P.A. Tablets incorporating isoflavone plant extracts and methods of manufacturing them
EP1175390B1 (en) 1999-04-05 2005-02-02 Emisphere Technologies, Inc. Disodium salts, monohydrates, and ethanol solvates
SK285128B6 (sk) * 1999-12-28 2006-07-07 Zentiva, A. S. Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy
US6544553B1 (en) * 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents

Also Published As

Publication number Publication date
CN1809377A (zh) 2006-07-26
US20070065505A1 (en) 2007-03-22
US20080234179A1 (en) 2008-09-25
JP2009513528A (ja) 2009-04-02
WO2005004900A1 (en) 2005-01-20
EP1651248A1 (en) 2006-05-03
AU2004255458B2 (en) 2007-09-13
AU2004255458A1 (en) 2005-01-20
ES2330638T3 (es) 2009-12-14
JP5032844B2 (ja) 2012-09-26
US8748383B2 (en) 2014-06-10
CA2529604A1 (en) 2005-01-20
US20130230593A1 (en) 2013-09-05
ATE442158T1 (de) 2009-09-15
CA2529604C (en) 2012-05-08
BRPI0412458A (pt) 2006-10-17
MXPA06000446A (es) 2006-04-07
DE602004023093D1 (de) 2009-10-22
HK1089950A1 (en) 2006-12-15
PL1651248T3 (pl) 2010-02-26
EP1651248B1 (en) 2009-09-09
CN1809377B (zh) 2010-08-04
US8435946B2 (en) 2013-05-07

Similar Documents

Publication Publication Date Title
HK1089950A1 (en) Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form
AU3454702A (en) Pharmaceutical compositions for the oral delivery of pharmacologically active agents
WO2008021088A3 (en) Salicylanilides enhance oral delivery of therapeutic peptides
GEP20074231B (en) Calcitonin gene related peptide receptor antagonists
MX2007015480A (es) Formulaciones de dosificacion solida de medicamentos narcoticos que tienen adsorcion bucal mejorada.
TWI366460B (en) Cannabinoid active pharmaceutical ingredient for improved dosage forms
WO2007008752A3 (en) Sustained release pharmaceutical compositions for highly water soluble drugs
GEP20074047B (en) Pramipexole once-daily dosage form
MXPA05007609A (es) Antagonista de un receptor sensible al calcio.
ZA200709788B (en) Cannabinold active pharmaceutical ingredient for Improved dosage forms
MXPA03010054A (es) Composiciones que comprenden lopinavir y metodos para aumentar la biodisponibilidad de agentes farmaceuticos.
TW200638927A (en) Bambuterol and integrin inhibitor combination
WO2007011958A3 (en) Intraoral dosage forms of glucagon
EA200600953A1 (ru) Дозированные формы торсемида пролонгированного высвобождения
ATE460934T1 (de) Pharmazeutische zubereitungen von ciprofloxacin
WO2007035816A3 (en) Paroxetine compositions
WO2006030303A8 (en) Oral extended release dosage form comprising a high dose biguanide and a low dose sulfonylurea
WO2005062722A3 (en) Fexofenadine containing pharmaceutical formulation
SI1653963T1 (sl) Farmacevtski sestavek piribedila za nazalno aplikacijo
HUP0500270A2 (en) Pharmacologically active peptide derivatives, process for their preparation and pharmaceutical compositions containing the same
TNSN06299A1 (en) Oral matrix formulations comprising licarbazepine
UY27122A1 (es) Una composición farmacéutica que comprende de 2 a 4 mg de 5-(a-(2-(n-metil-n-(2-piridil)amino)etoxi)bencil)tiazolidin-2,4-diona
SI1471890T1 (sl) Farmacevtska dozirna oblika za dajanje v sluznico
ECSP024344A (es) Composiciones farmaceuticas
TW200608982A (en) Oral formulations of paricalcitol