HK1089950A1 - Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form - Google Patents
Orally dosed pharmaceutical compositions comprising a delivery agent in micronized formInfo
- Publication number
- HK1089950A1 HK1089950A1 HK06110477.5A HK06110477A HK1089950A1 HK 1089950 A1 HK1089950 A1 HK 1089950A1 HK 06110477 A HK06110477 A HK 06110477A HK 1089950 A1 HK1089950 A1 HK 1089950A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pharmaceutical compositions
- delivery agent
- pharmacologically active
- micronized form
- orally dosed
- Prior art date
Links
- 229940124447 delivery agent Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 2
- 102000055006 Calcitonin Human genes 0.000 abstract 1
- 108060001064 Calcitonin Proteins 0.000 abstract 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 1
- 229960004015 calcitonin Drugs 0.000 abstract 1
- 229960000913 crospovidone Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 abstract 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 229940069328 povidone Drugs 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Permanent Magnet Type Synchronous Machine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48649503P | 2003-07-11 | 2003-07-11 | |
| PCT/EP2004/007584 WO2005004900A1 (en) | 2003-07-11 | 2004-07-09 | Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1089950A1 true HK1089950A1 (en) | 2006-12-15 |
Family
ID=34062133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06110477.5A HK1089950A1 (en) | 2003-07-11 | 2006-09-20 | Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20070065505A1 (pt) |
| EP (1) | EP1651248B1 (pt) |
| JP (1) | JP5032844B2 (pt) |
| CN (1) | CN1809377B (pt) |
| AT (1) | ATE442158T1 (pt) |
| AU (1) | AU2004255458B2 (pt) |
| BR (1) | BRPI0412458A (pt) |
| CA (1) | CA2529604C (pt) |
| DE (1) | DE602004023093D1 (pt) |
| ES (1) | ES2330638T3 (pt) |
| HK (1) | HK1089950A1 (pt) |
| MX (1) | MXPA06000446A (pt) |
| PL (1) | PL1651248T3 (pt) |
| PT (1) | PT1651248E (pt) |
| WO (1) | WO2005004900A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4959917B2 (ja) * | 2001-08-17 | 2012-06-27 | ノバルティス アーゲー | 副甲状腺ホルモンフラグメント用経口送達剤としての５−ｃｎａｃ |
| US20060078622A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
| KR20080049128A (ko) | 2005-09-19 | 2008-06-03 | 에미스페어 테크놀로지스, 인코포레이티드 | Ｎ-(5-클로로살리실로일)-8-아미노카프릴산 이나트륨염의결정형 |
| GB0522566D0 (en) * | 2005-11-04 | 2005-12-14 | Novartis Ag | Organic compounds |
| ES2426485T3 (es) * | 2006-08-31 | 2013-10-23 | Novartis Ag | Composiciones farmacéuticas que comprenden hGH para administración oral |
| AR062925A1 (es) * | 2006-09-22 | 2008-12-17 | Novartis Ag | Metodo para fabricar tabletas que contienen agentes farmacologicamente activos |
| PL2215047T3 (pl) * | 2007-11-02 | 2014-05-30 | Emisphere Tech Inc | Sposób leczenia niedoborów witaminy b12 |
| RU2576511C2 (ru) * | 2010-02-24 | 2016-03-10 | Эмисфире Текнолоджис, Инк. | Пероральная терапия недостаточности витамина в12 |
| DK2651398T3 (en) | 2010-12-16 | 2018-03-12 | Novo Nordisk As | Solid compositions comprising a GLP-1 agonist and a salt of N- (8- (2-hydroxybenzyl) amino) caprylic acid |
| KR101972836B1 (ko) | 2011-04-12 | 2019-04-29 | 노보 노르디스크 에이/에스 | 이중 아실화된 ｇｌｐ-1 유도체 |
| CN111494324B (zh) | 2012-03-22 | 2023-05-16 | 诺和诺德股份有限公司 | 包含递送剂的组合物及其制备 |
| DK2827845T3 (en) | 2012-03-22 | 2019-04-01 | Novo Nordisk As | COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF |
| RS57727B1 (sr) | 2012-03-22 | 2018-12-31 | Novo Nordisk As | Kompozicije glp-1 peptida i njihovo dobijanje |
| CN104487056A (zh) | 2012-06-20 | 2015-04-01 | 诺和诺德A/S（股份有限公司） | 包含肽和递送剂的片剂制剂 |
| CN104095828A (zh) * | 2014-07-29 | 2014-10-15 | 中国药科大学 | 一种降钙素口服肠溶组合物及其制备方法 |
| WO2019149880A1 (en) | 2018-02-02 | 2019-08-08 | Novo Nordisk A/S | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
| EP4326329A1 (en) | 2021-04-22 | 2024-02-28 | Civi Biopharma, Inc. | Oral delivery of oligonucleotides |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| US5866536A (en) * | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
| US6413546B1 (en) * | 1999-03-18 | 2002-07-02 | Indena, S.P.A. | Tablets incorporating isoflavone plant extracts and methods of manufacturing them |
| EP1175390B1 (en) | 1999-04-05 | 2005-02-02 | Emisphere Technologies, Inc. | Disodium salts, monohydrates, and ethanol solvates |
| SK285128B6 (sk) * | 1999-12-28 | 2006-07-07 | Zentiva, A. S. | Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy |
| US6544553B1 (en) * | 1999-12-28 | 2003-04-08 | Watson Pharmaceuticals, Inc. | Dosage forms and methods for oral delivery of progesterone |
| US7049283B2 (en) * | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
-
2004
- 2004-07-09 PL PL04740863T patent/PL1651248T3/pl unknown
- 2004-07-09 JP JP2006518162A patent/JP5032844B2/ja not_active Expired - Fee Related
- 2004-07-09 US US10/564,259 patent/US20070065505A1/en not_active Abandoned
- 2004-07-09 ES ES04740863T patent/ES2330638T3/es not_active Expired - Lifetime
- 2004-07-09 CA CA2529604A patent/CA2529604C/en not_active Expired - Fee Related
- 2004-07-09 PT PT04740863T patent/PT1651248E/pt unknown
- 2004-07-09 CN CN2004800174065A patent/CN1809377B/zh not_active Expired - Fee Related
- 2004-07-09 EP EP04740863A patent/EP1651248B1/en not_active Expired - Lifetime
- 2004-07-09 AU AU2004255458A patent/AU2004255458B2/en not_active Ceased
- 2004-07-09 DE DE602004023093T patent/DE602004023093D1/de not_active Expired - Lifetime
- 2004-07-09 BR BRPI0412458-8A patent/BRPI0412458A/pt not_active Application Discontinuation
- 2004-07-09 MX MXPA06000446A patent/MXPA06000446A/es active IP Right Grant
- 2004-07-09 WO PCT/EP2004/007584 patent/WO2005004900A1/en active Application Filing
- 2004-07-09 AT AT04740863T patent/ATE442158T1/de active
-
2006
- 2006-09-20 HK HK06110477.5A patent/HK1089950A1/xx not_active IP Right Cessation
-
2008
- 2008-06-04 US US12/132,642 patent/US8435946B2/en active Active
-
2013
- 2013-04-15 US US13/862,811 patent/US8748383B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1809377A (zh) | 2006-07-26 |
| US20070065505A1 (en) | 2007-03-22 |
| PT1651248E (pt) | 2009-11-10 |
| US20080234179A1 (en) | 2008-09-25 |
| JP2009513528A (ja) | 2009-04-02 |
| WO2005004900A1 (en) | 2005-01-20 |
| EP1651248A1 (en) | 2006-05-03 |
| AU2004255458B2 (en) | 2007-09-13 |
| AU2004255458A1 (en) | 2005-01-20 |
| ES2330638T3 (es) | 2009-12-14 |
| JP5032844B2 (ja) | 2012-09-26 |
| US8748383B2 (en) | 2014-06-10 |
| CA2529604A1 (en) | 2005-01-20 |
| US20130230593A1 (en) | 2013-09-05 |
| ATE442158T1 (de) | 2009-09-15 |
| CA2529604C (en) | 2012-05-08 |
| BRPI0412458A (pt) | 2006-10-17 |
| MXPA06000446A (es) | 2006-04-07 |
| DE602004023093D1 (de) | 2009-10-22 |
| PL1651248T3 (pl) | 2010-02-26 |
| EP1651248B1 (en) | 2009-09-09 |
| CN1809377B (zh) | 2010-08-04 |
| US8435946B2 (en) | 2013-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230709 |