PT1596862E - Uso de palonosetron para tratamento de náuseas e vómitos no pósoperatório - Google Patents

Uso de palonosetron para tratamento de náuseas e vómitos no pósoperatório Download PDF

Info

Publication number
PT1596862E
PT1596862E PT04712041T PT04712041T PT1596862E PT 1596862 E PT1596862 E PT 1596862E PT 04712041 T PT04712041 T PT 04712041T PT 04712041 T PT04712041 T PT 04712041T PT 1596862 E PT1596862 E PT 1596862E
Authority
PT
Portugal
Prior art keywords
vomiting
palonosetron
operative nausea
treating post
post
Prior art date
Application number
PT04712041T
Other languages
English (en)
Portuguese (pt)
Inventor
Enrico Braglia
Riccardo Braglia
Luigi Baroni
Alberto Macciocchi
Original Assignee
Helsinn Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32908576&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1596862(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Helsinn Healthcare Sa filed Critical Helsinn Healthcare Sa
Publication of PT1596862E publication Critical patent/PT1596862E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
PT04712041T 2003-02-18 2004-02-18 Uso de palonosetron para tratamento de náuseas e vómitos no pósoperatório PT1596862E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44834203P 2003-02-18 2003-02-18

Publications (1)

Publication Number Publication Date
PT1596862E true PT1596862E (pt) 2011-03-15

Family

ID=32908576

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04712041T PT1596862E (pt) 2003-02-18 2004-02-18 Uso de palonosetron para tratamento de náuseas e vómitos no pósoperatório

Country Status (31)

Country Link
US (1) US20060074101A1 (enExample)
EP (2) EP1596862B1 (enExample)
JP (1) JP2006517944A (enExample)
KR (1) KR101113087B1 (enExample)
CN (1) CN1750822A (enExample)
AT (1) ATE490774T1 (enExample)
AU (1) AU2004212704B2 (enExample)
BR (1) BRPI0407549A (enExample)
CA (1) CA2515946C (enExample)
CU (1) CU23587B7 (enExample)
CY (1) CY1111312T1 (enExample)
DE (1) DE602004030424D1 (enExample)
DK (1) DK1596862T3 (enExample)
EA (1) EA013836B1 (enExample)
EC (1) ECSP055970A (enExample)
ES (1) ES2357769T3 (enExample)
GE (1) GEP20104908B (enExample)
HR (1) HRP20050709A2 (enExample)
IS (1) IS7983A (enExample)
MX (1) MXPA05008757A (enExample)
MY (1) MY143789A (enExample)
NO (1) NO20054296L (enExample)
NZ (1) NZ541862A (enExample)
PL (1) PL378122A1 (enExample)
PT (1) PT1596862E (enExample)
SI (1) SI1596862T1 (enExample)
TW (1) TWI355936B (enExample)
UA (1) UA96254C2 (enExample)
UY (1) UY28193A1 (enExample)
WO (1) WO2004073714A1 (enExample)
ZA (1) ZA200506580B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5690461B2 (ja) * 2002-11-15 2015-03-25 ヘルシン ヘルスケア ソシエテ アノニム 化学療法誘導嘔吐を治療するためのパロノセトロン
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formulations of palonosetron
US8598219B2 (en) 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
US20070196491A1 (en) * 2006-01-27 2007-08-23 Eurand, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
JP5433236B2 (ja) * 2006-01-27 2014-03-05 アプタリス ファーマテック，インコーポレイテッド 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系
EA016455B1 (ru) * 2006-10-24 2012-05-30 Хелсинн Хелткэр С.А. Мягкие капсулы, содержащие палоносетрона гидрохлорид, имеющие улучшенную стабильность и биологическую доступность
TWI429436B (zh) * 2007-04-10 2014-03-11 Helsinn Therapeutics Us Inc 使用生長激素促泌素治療或預防嘔吐之方法
US20090155363A1 (en) * 2007-12-14 2009-06-18 Todd Maibach Methods for oral administration of active drugs
JP5547065B2 (ja) 2008-05-15 2014-07-09 久光製薬株式会社 パロノセトロンを含有する経皮吸収製剤
EP2364138A2 (en) * 2008-12-08 2011-09-14 Teva Pharmaceutical Industries Ltd. Palonosetron formulation
ES2432618T3 (es) * 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular
EP2432467B1 (en) 2009-05-20 2018-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Serotonin 5-ht3 receptor antagonists for use in the treatment of lesional vestibular disorders
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
EP2499137A1 (en) 2009-11-13 2012-09-19 Helsinn Healthcare S.A. Palonosetron metabolites
EP2722045B1 (en) 2009-11-18 2016-07-06 Helsinn Healthcare SA Compositions for treating centrally mediated nausea and vomiting
PE20121483A1 (es) 2009-11-18 2012-12-02 Helsinn Healthcare Sa Composiciones para tratar nausea y vomito centralmente mediados
KR101368587B1 (ko) * 2010-12-27 2014-03-05 주식회사 삼양바이오팜 오심 또는 구토 방지용 조성물
US10071088B2 (en) 2012-06-26 2018-09-11 Precondit, Llc Anti-nausea drug combinations
EP3087987A4 (en) 2013-12-23 2017-08-02 Samyang Biopharmaceuticals Corporation Pharmaceutical composition containing palonosetron
HRP20240453T1 (hr) 2016-04-14 2024-06-21 Sensorion (+)-azasetron za uporabu u liječenju poremećaja uha
JP6768404B2 (ja) * 2016-08-12 2020-10-14 武田テバファーマ株式会社 パロノセトロン又はその薬学的に許容される塩を含む医薬組成物
JP6705348B2 (ja) * 2016-09-23 2020-06-03 ニプロ株式会社 液体製剤、及び、パロノセトロンの安定性を向上する方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
KR101802183B1 (ko) * 2016-11-16 2017-11-28 주식회사 유영제약 팔로노세트론을 활성성분으로 함유하는 약제학적 조성물
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
US11433021B2 (en) 2018-01-12 2022-09-06 Orion Corporation Palonosetron for the treatment or prevention of nausea and vomiting
CN108703960A (zh) * 2018-07-25 2018-10-26 无锡鑫连鑫生物医药科技有限公司 一种帕洛诺司琼缓释微球及其制备方法和使用方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695578A (en) 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
US4937247A (en) 1985-04-27 1990-06-26 Beecham Group P.L.C. 1-acyl indazoles
DE3687080T2 (de) 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.
US5240954A (en) 1985-06-25 1993-08-31 Glaxo Group Limited Medicaments
US5578628A (en) 1985-06-25 1996-11-26 Glaxo Group Limited Medicaments for the treatment of nausea and vomiting
GB8516083D0 (en) 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
US4906755A (en) 1986-11-03 1990-03-06 Merrell Dow Pharmaceuticals Inc. Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds
US4707484A (en) 1986-11-25 1987-11-17 Hoffmann-La Roche Inc. Substituted piperidinomethylindolone and cyclopent(b)indolone derivatives
US5011846A (en) 1988-02-23 1991-04-30 Merrell Dow Pharmaceuticals Inc. Medicament compositions derived from quinolizine and quinolizinone and methods of use thereof
GB8914804D0 (en) * 1989-06-28 1989-08-16 Glaxo Group Ltd Process
US5344658A (en) * 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
AU642178B2 (en) * 1989-11-28 1993-10-14 Roche Palo Alto Llc New tricyclic compounds
US5189041A (en) 1990-11-16 1993-02-23 Syntex (U.S.A.) Inc. Tricyclic 5-ht3 receptor antagonists
US5137893A (en) 1991-03-07 1992-08-11 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5491148A (en) 1991-04-26 1996-02-13 Syntex (U.S.A.) Inc. Isoquinolinone and dihydroisoquinolinone 5-HT3 receptor antagonists
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
GB9305593D0 (en) 1993-03-18 1993-05-05 Smithkline Beecham Plc Pharmaceuticals
US5492914A (en) 1994-07-28 1996-02-20 Syntex (U.S.A.) Inc. 2-(1-azabicyclo[2.2.2]oct-3 s-yl)-6-hydroxy-2,4,5,6-tetrahydro-1H-benz[DE]is[2.2.2]oct-3's-yl)-6-hydroxy-2,3,3a,4,5,6-hexahydro-1h-benz [DE]isoquinolin-1-one and individual stereoisomers thereof
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423511D0 (en) 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9625589D0 (en) * 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
US20030095926A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US6294548B1 (en) 1998-05-04 2001-09-25 Hoffmann-La Roche Inc. Multidose vial formulations for administering endo-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
EP1085888A1 (en) * 1998-06-08 2001-03-28 Advanced Medicine, Inc. Multivalent agonists, partial agonists, inverse agonists and antagonists of the 5-ht 3? receptors
BR9914799A (pt) * 1998-10-27 2001-07-10 Alcon Lab Inc Sistema conservante para composições farmacêuticas administráveis topicamente contendo um sabão de ácido graxo/aminoácido
US6196963B1 (en) * 1999-03-02 2001-03-06 Medtronic Ave, Inc. Brachytherapy device assembly and method of use
AU2003237657A1 (en) * 2002-05-24 2003-12-12 Epidauros Biotechnologie Ag Means and methods for improved treatment using "setrones"
JP5690461B2 (ja) * 2002-11-15 2015-03-25 ヘルシン ヘルスケア ソシエテ アノニム 化学療法誘導嘔吐を治療するためのパロノセトロン
US8598219B2 (en) * 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formulations of palonosetron

Also Published As

Publication number Publication date
EA013836B1 (ru) 2010-08-30
PL378122A1 (pl) 2006-03-06
ES2357769T3 (es) 2011-04-29
CY1111312T1 (el) 2015-08-05
KR101113087B1 (ko) 2012-02-15
AU2004212704A1 (en) 2004-09-02
NO20054296L (no) 2005-11-17
CN1750822A (zh) 2006-03-22
CU23587B7 (es) 2010-10-30
CA2515946C (en) 2008-12-02
TW200418474A (en) 2004-10-01
HRP20050709A2 (en) 2005-12-31
DK1596862T3 (da) 2011-03-28
MXPA05008757A (es) 2006-05-31
UA96254C2 (uk) 2011-10-25
EP2258367A3 (en) 2011-07-13
UY28193A1 (es) 2004-09-30
IS7983A (is) 2005-08-15
AU2004212704B2 (en) 2009-10-01
WO2004073714A1 (en) 2004-09-02
GEP20104908B (en) 2010-03-10
EA200501318A1 (ru) 2006-02-24
JP2006517944A (ja) 2006-08-03
EP1596862A1 (en) 2005-11-23
CA2515946A1 (en) 2004-09-02
NO20054296D0 (no) 2005-09-16
ECSP055970A (es) 2006-01-16
EP1596862B1 (en) 2010-12-08
KR20050121671A (ko) 2005-12-27
NZ541862A (en) 2008-04-30
SI1596862T1 (sl) 2011-03-31
US20060074101A1 (en) 2006-04-06
EP2258367A2 (en) 2010-12-08
ZA200506580B (en) 2006-06-28
BRPI0407549A (pt) 2006-02-14
MY143789A (en) 2011-07-15
HK1076402A1 (en) 2006-01-20
TWI355936B (en) 2012-01-11
DE602004030424D1 (de) 2011-01-20
ATE490774T1 (de) 2010-12-15

Similar Documents

Publication Publication Date Title
HRP20050709A2 (en) Use of palonosetron treating post-operative nausea and vomiting
AU2003272285A8 (en) Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands
UA89734C2 (en) ANTAGONISTS of muscarinic acetylcholine receptors
MY144753A (en) Muscarinic acetylcholine receptor antagonists
TW200745112A (en) Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators
SG170033A1 (en) Octahydro-pyrrolo[3,4-b] pyrrole derivatives and their use as histamine-3 receptor ligands
WO2009155054A3 (en) 5-ht3 receptor modulators, methods of making, and use thereof
PL369889A1 (en) Anticholinergic agents, method for producing the same and use thereof as medicaments
CA2505990A1 (en) Palonosetron for the treatment of chemotherapy-induced emesis
BRPI0412629A (pt) método de tratamento de disfunção ocular em mamìferos
MXPA06000662A (es) Antagonistas del receptor muscarinico de acetilcolina.
TW200519109A (en) Muscarinic acetylcholine receptor antagonists
MXPA06000663A (es) Antagonistas del receptor muscarinico de acetilcolina.
WO2006011811A3 (en) Radicals and their use as paramagnetic agents in a dynamic nuclear polarisation process
IL164606A0 (en) Novel compounds
TW200700065A (en) Phenanthroindolizidine alkaloids
MXPA02012244A (es) 1-aminoalquilciclohexanos como 5-ht3 y antagonistas de receptor nicotinico neuronal.
TW200606161A (en) Muscarinic acetylcholine receptor antagonists
UA83203C2 (uk) Тіазол-(бі)циклоалкілкарбоксаніліди, засіб на їх основі та застосування для боротьби з небажаними мікроорганізмами
MX2007016373A (es) Compuestos de piridil y piridonil estereoisomericos y metodos para el tratamiento de trastornos gastrointestinales y del sistema nervioso central.
WO2006016192A3 (en) Combination therapy with nk3 receptor antagonists for the treatment of schizophrenia
WO2005079464A3 (en) Vitamin d receptor antagonists and their use in treating asthma
NZ511997A (en) Isonipecotamides for the treatment of integrin-mediated disorders
CR7949A (es) Metodo para el tratamiento post operatorio de nausea y vomito
MXPA05008862A (es) Heterociclos de nitrogeno n-arilo sustituidos.