PT1558620E - Complexos anticancerígenos de ruténio - Google Patents

Complexos anticancerígenos de ruténio Download PDF

Info

Publication number
PT1558620E
PT1558620E PT03762788T PT03762788T PT1558620E PT 1558620 E PT1558620 E PT 1558620E PT 03762788 T PT03762788 T PT 03762788T PT 03762788 T PT03762788 T PT 03762788T PT 1558620 E PT1558620 E PT 1558620E
Authority
PT
Portugal
Prior art keywords
ruthenium
anticancer complexes
ruthenium anticancer
complexes
formula
Prior art date
Application number
PT03762788T
Other languages
English (en)
Inventor
Peter John Sadler
Rafael Fernandez Lainez
Abraba Habtemariam
Michael Melchart
Duncan Ian Jodrell
Original Assignee
Univ Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Edinburgh filed Critical Univ Edinburgh
Publication of PT1558620E publication Critical patent/PT1558620E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00Metallocenes
    • C07F17/02Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT03762788T 2002-07-05 2003-07-04 Complexos anticancerígenos de ruténio PT1558620E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0215526.5A GB0215526D0 (en) 2002-07-05 2002-07-05 Anticancer compounds

Publications (1)

Publication Number Publication Date
PT1558620E true PT1558620E (pt) 2008-12-03

Family

ID=9939861

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03762788T PT1558620E (pt) 2002-07-05 2003-07-04 Complexos anticancerígenos de ruténio

Country Status (20)

Country Link
US (1) US20060058270A1 (pt)
EP (1) EP1558620B1 (pt)
JP (1) JP2005536487A (pt)
KR (1) KR20050053589A (pt)
CN (1) CN100362005C (pt)
AT (1) ATE407937T1 (pt)
AU (1) AU2003251159B2 (pt)
BR (1) BR0312470A (pt)
CA (1) CA2491640A1 (pt)
DE (1) DE60323529D1 (pt)
DK (1) DK1558620T3 (pt)
ES (1) ES2314245T3 (pt)
GB (1) GB0215526D0 (pt)
MX (1) MXPA05000314A (pt)
NO (1) NO20050640L (pt)
NZ (1) NZ538005A (pt)
PL (1) PL373049A1 (pt)
PT (1) PT1558620E (pt)
WO (1) WO2004005304A1 (pt)
ZA (1) ZA200500908B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1224192T3 (da) * 1999-10-27 2006-01-02 Univ Court The University Of E Halvsandwich-ruthenium (II)-forbindelser omfattende nitrogenholdige ligander til behandling af cancer
CN100368418C (zh) 2003-04-30 2008-02-13 爱丁堡大学董事会 用于治疗肿瘤的钌(ⅱ)络合物
GB0418643D0 (en) * 2004-08-20 2004-09-22 Univ Edinburgh Ruthenium (II) compounds
GB0604602D0 (en) * 2006-03-07 2006-04-19 Univ Edinburgh Ruthenium (II) compounds
WO2007128158A1 (en) 2006-05-09 2007-11-15 Ecole Polytechnique Federale De Lausanne (Epfl) Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis
GB0610062D0 (en) * 2006-05-19 2006-06-28 Univ Edinburgh Ruthenium (ll) compounds
DE102009053392A1 (de) * 2009-11-14 2011-06-22 Umicore AG & Co. KG, 63457 Verfahren zur Herstellung von Ru(0) Olefin-Komplexen
WO2013038395A1 (en) 2011-09-16 2013-03-21 Universidade De Lisboa Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en) 2012-03-14 2013-09-19 Universidade De Lisboa Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
CN103360428A (zh) * 2012-04-09 2013-10-23 中国科学院化学研究所 抑制蛋白酪氨酸磷酸酶1b活性的含钌配合物及其制备方法和蛋白酪氨酸磷酸酶1b抑制剂
CN102964385B (zh) * 2012-11-30 2015-02-18 广西师范学院 一种有机金属钌化合物及其制备方法和用途
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980473A (en) * 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
EP1300381B1 (en) * 1995-12-06 2006-03-08 Japan Science and Technology Agency Process for preparing optically active alcohols
DK1224192T3 (da) * 1999-10-27 2006-01-02 Univ Court The University Of E Halvsandwich-ruthenium (II)-forbindelser omfattende nitrogenholdige ligander til behandling af cancer
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds

Also Published As

Publication number Publication date
EP1558620A1 (en) 2005-08-03
DE60323529D1 (de) 2008-10-23
NO20050640L (no) 2005-03-22
NZ538005A (en) 2007-08-31
MXPA05000314A (es) 2005-09-20
ATE407937T1 (de) 2008-09-15
WO2004005304A1 (en) 2004-01-15
ES2314245T3 (es) 2009-03-16
CA2491640A1 (en) 2004-01-15
BR0312470A (pt) 2005-04-26
KR20050053589A (ko) 2005-06-08
ZA200500908B (en) 2006-03-29
AU2003251159B2 (en) 2008-11-06
AU2003251159A1 (en) 2004-01-23
US20060058270A1 (en) 2006-03-16
DK1558620T3 (da) 2009-01-05
JP2005536487A (ja) 2005-12-02
CN100362005C (zh) 2008-01-16
CN1665826A (zh) 2005-09-07
EP1558620B1 (en) 2008-09-10
GB0215526D0 (en) 2002-08-14
PL373049A1 (en) 2005-08-08

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