DK1558620T3 - Rutheniumkomplekser med anticancervirkning - Google Patents

Rutheniumkomplekser med anticancervirkning

Info

Publication number
DK1558620T3
DK1558620T3 DK03762788T DK03762788T DK1558620T3 DK 1558620 T3 DK1558620 T3 DK 1558620T3 DK 03762788 T DK03762788 T DK 03762788T DK 03762788 T DK03762788 T DK 03762788T DK 1558620 T3 DK1558620 T3 DK 1558620T3
Authority
DK
Denmark
Prior art keywords
anticancer effect
ruthenium complexes
ruthenium
formula
complexes
Prior art date
Application number
DK03762788T
Other languages
English (en)
Inventor
Peter John Sadler
Lainez Rafael Fernandez
Abraba Habtemariam
Michael Melchart
Duncan Ian Jodrell
Original Assignee
Univ Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Edinburgh filed Critical Univ Edinburgh
Application granted granted Critical
Publication of DK1558620T3 publication Critical patent/DK1558620T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00Metallocenes
    • C07F17/02Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK03762788T 2002-07-05 2003-07-04 Rutheniumkomplekser med anticancervirkning DK1558620T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0215526.5A GB0215526D0 (en) 2002-07-05 2002-07-05 Anticancer compounds
PCT/GB2003/002879 WO2004005304A1 (en) 2002-07-05 2003-07-04 Ruthenium anticancer complexes

Publications (1)

Publication Number Publication Date
DK1558620T3 true DK1558620T3 (da) 2009-01-05

Family

ID=9939861

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03762788T DK1558620T3 (da) 2002-07-05 2003-07-04 Rutheniumkomplekser med anticancervirkning

Country Status (20)

Country Link
US (1) US20060058270A1 (da)
EP (1) EP1558620B1 (da)
JP (1) JP2005536487A (da)
KR (1) KR20050053589A (da)
CN (1) CN100362005C (da)
AT (1) ATE407937T1 (da)
AU (1) AU2003251159B2 (da)
BR (1) BR0312470A (da)
CA (1) CA2491640A1 (da)
DE (1) DE60323529D1 (da)
DK (1) DK1558620T3 (da)
ES (1) ES2314245T3 (da)
GB (1) GB0215526D0 (da)
MX (1) MXPA05000314A (da)
NO (1) NO20050640L (da)
NZ (1) NZ538005A (da)
PL (1) PL373049A1 (da)
PT (1) PT1558620E (da)
WO (1) WO2004005304A1 (da)
ZA (1) ZA200500908B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2248136T3 (es) * 1999-10-27 2006-03-16 The University Court, The University Of Edinburgh Compuesto de rutenio (ii) semi-sandwich que comprenden ligandos que contienen nitrogeno para el tratamiento del cancer.
DE602004014125D1 (de) 2003-04-30 2008-07-10 Univ Edinburgh Ruthenium(ii)-komplexe zur behandlung von tumoren
GB0418643D0 (en) * 2004-08-20 2004-09-22 Univ Edinburgh Ruthenium (II) compounds
GB0604602D0 (en) * 2006-03-07 2006-04-19 Univ Edinburgh Ruthenium (II) compounds
US9018199B2 (en) * 2006-05-09 2015-04-28 Ecole Polytechnique Federale De Lausanne (Epfl) Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis
GB0610062D0 (en) * 2006-05-19 2006-06-28 Univ Edinburgh Ruthenium (ll) compounds
DE102009053392A1 (de) * 2009-11-14 2011-06-22 Umicore AG & Co. KG, 63457 Verfahren zur Herstellung von Ru(0) Olefin-Komplexen
WO2013038395A1 (en) 2011-09-16 2013-03-21 Universidade De Lisboa Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en) 2012-03-14 2013-09-19 Universidade De Lisboa Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
CN103360428A (zh) * 2012-04-09 2013-10-23 中国科学院化学研究所 抑制蛋白酪氨酸磷酸酶1b活性的含钌配合物及其制备方法和蛋白酪氨酸磷酸酶1b抑制剂
CN102964385B (zh) * 2012-11-30 2015-02-18 广西师范学院 一种有机金属钌化合物及其制备方法和用途
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980473A (en) * 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
EP1300381B1 (en) * 1995-12-06 2006-03-08 Japan Science and Technology Agency Process for preparing optically active alcohols
ES2248136T3 (es) * 1999-10-27 2006-03-16 The University Court, The University Of Edinburgh Compuesto de rutenio (ii) semi-sandwich que comprenden ligandos que contienen nitrogeno para el tratamiento del cancer.
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds

Also Published As

Publication number Publication date
DE60323529D1 (de) 2008-10-23
US20060058270A1 (en) 2006-03-16
EP1558620A1 (en) 2005-08-03
AU2003251159B2 (en) 2008-11-06
EP1558620B1 (en) 2008-09-10
ES2314245T3 (es) 2009-03-16
NO20050640L (no) 2005-03-22
CN100362005C (zh) 2008-01-16
BR0312470A (pt) 2005-04-26
MXPA05000314A (es) 2005-09-20
JP2005536487A (ja) 2005-12-02
AU2003251159A1 (en) 2004-01-23
GB0215526D0 (en) 2002-08-14
PL373049A1 (en) 2005-08-08
CA2491640A1 (en) 2004-01-15
CN1665826A (zh) 2005-09-07
WO2004005304A1 (en) 2004-01-15
ZA200500908B (en) 2006-03-29
PT1558620E (pt) 2008-12-03
NZ538005A (en) 2007-08-31
ATE407937T1 (de) 2008-09-15
KR20050053589A (ko) 2005-06-08

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