PT1465663E - Soluções injectáveis prontas a usar de paracetamol contendo propilenoglicol como o único co-solvente - Google Patents

Soluções injectáveis prontas a usar de paracetamol contendo propilenoglicol como o único co-solvente Download PDF

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Publication number
PT1465663E
PT1465663E PT02779486T PT02779486T PT1465663E PT 1465663 E PT1465663 E PT 1465663E PT 02779486 T PT02779486 T PT 02779486T PT 02779486 T PT02779486 T PT 02779486T PT 1465663 E PT1465663 E PT 1465663E
Authority
PT
Portugal
Prior art keywords
ready
propylene glycol
cosolvent
solutions containing
injection solutions
Prior art date
Application number
PT02779486T
Other languages
English (en)
Inventor
Thao Nguyen-Xuan
Original Assignee
Bigmar Bioren Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bigmar Bioren Pharmaceuticals filed Critical Bigmar Bioren Pharmaceuticals
Publication of PT1465663E publication Critical patent/PT1465663E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT02779486T 2001-10-16 2002-10-15 Soluções injectáveis prontas a usar de paracetamol contendo propilenoglicol como o único co-solvente PT1465663E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI002135A ITMI20012135A1 (it) 2001-10-16 2001-10-16 Soluzioni iniettabili pronte all'uso di paracetamolo

Publications (1)

Publication Number Publication Date
PT1465663E true PT1465663E (pt) 2008-04-10

Family

ID=11448506

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02779486T PT1465663E (pt) 2001-10-16 2002-10-15 Soluções injectáveis prontas a usar de paracetamol contendo propilenoglicol como o único co-solvente

Country Status (15)

Country Link
US (1) US8178121B2 (pt)
EP (1) EP1465663B1 (pt)
JP (1) JP4543679B2 (pt)
CN (1) CN1274293C (pt)
AT (1) ATE382369T1 (pt)
AU (1) AU2002342826B2 (pt)
CA (1) CA2463681C (pt)
DE (1) DE60224449T2 (pt)
DK (1) DK1465663T3 (pt)
ES (1) ES2301685T3 (pt)
IL (2) IL161390A0 (pt)
IT (1) ITMI20012135A1 (pt)
NZ (1) NZ532936A (pt)
PT (1) PT1465663E (pt)
WO (1) WO2003033026A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2851164B1 (fr) 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
FR2862872A1 (fr) * 2003-12-02 2005-06-03 Palbian Snc Composition a l'etat aqueux pour l'application perfusable d'un principe actif, notamment pharmacologique tel que le paracetamol.
US9585849B2 (en) * 2006-04-17 2017-03-07 The Burlington Hc Research Group, Inc. Broad spectrum antiviral and methods of use
EP2010166B1 (en) * 2006-04-17 2013-11-06 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Organic disulfide antiretroviral agents
AU2006346318B2 (en) 2006-07-18 2011-02-10 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
EP1992334A1 (en) * 2007-05-08 2008-11-19 Docpharma NV/SA Storage-stable formulation of oxidation-sensitive phenolic drug, especially paracetamol, comprises aqueous drug solution deoxygenated by a temperature-controlled manufacturing process of the formulation
BRPI0816478B1 (pt) * 2007-08-30 2018-02-14 Iogen Energy Corporation Processos de fermentação para a produção de uma mistura de celulases e de hidrólise de um substrato de celulose e uso de mistura de celulases em processo de fermentação
ES2321906B1 (es) * 2008-11-28 2010-02-09 Laboratorios Normon, S.A. Composicion farmaceutica que comprende una solucion acuosa de paracetamol.
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
EP2377516B1 (en) 2010-04-14 2012-06-20 B. Braun Melsungen AG Acetaminophen composition
ES2414557B1 (es) * 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
US20140303254A1 (en) * 2013-04-08 2014-10-09 InnoPharma Licensing LLC Process Of Manufacturing A Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation
BR102014005885B1 (pt) 2014-03-13 2021-04-13 Biotec Biológica Indústria Farmacêutica Ltda E.P.P Formulação farmacêutica líquida injetável estável de paracetamol em bolsa plástica pronta para uso
EA028075B1 (ru) * 2014-04-29 2017-10-31 Мыкола Ивановыч ГУМЕНЮК Фармацевтическая композиция
KR20170099911A (ko) 2014-12-20 2017-09-01 트로이카 파마슈티칼스 리미티드 파라세타몰 주사 제제

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3580140D1 (de) 1984-03-14 1990-11-22 Jerome Corbiere Verfahren zum loesen von wirksubstanzen und auf diese weise erhaltene arzneimittel.
KR930011994B1 (ko) * 1991-08-16 1993-12-23 대광제약 주식회사 파라세타몰의 생체이용율을 높이는 방법 및 이 생체이용율이 높아진 파라세타몰을 함유한 제제
JP3430320B2 (ja) 1994-03-14 2003-07-28 あづま姿株式会社 衣紋掛
JP3913795B2 (ja) * 1995-09-28 2007-05-09 エスエス製薬株式会社 安定な解熱鎮痛剤配合液剤
JPH09286724A (ja) * 1996-04-19 1997-11-04 Takeda Chem Ind Ltd 経口用安定液剤
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
US5766622A (en) * 1996-08-14 1998-06-16 The Procter & Gamble Company Inhibiting undesirable taste in oral compositions
IT1301976B1 (it) 1998-07-31 2000-07-20 Angelini Ricerche Spa Composizione farmaceutica iniettabile a base di paracetamolo
US6006659A (en) * 1998-10-13 1999-12-28 Rosenthal; Richard A. Personal pasteurization system
FR2809619B1 (fr) 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
DE10112325A1 (de) 2001-03-13 2002-10-02 Fresenius Kabi De Gmbh Lagerstabile Fertiginfusionslösungen des Paracetamols

Also Published As

Publication number Publication date
ES2301685T3 (es) 2008-07-01
ATE382369T1 (de) 2008-01-15
CN1274293C (zh) 2006-09-13
JP2005505609A (ja) 2005-02-24
IL161390A0 (en) 2004-09-27
EP1465663A1 (en) 2004-10-13
CA2463681C (en) 2011-03-15
DE60224449T2 (de) 2009-04-02
EP1465663B1 (en) 2008-01-02
IL161390A (en) 2009-06-15
DE60224449D1 (de) 2008-02-14
JP4543679B2 (ja) 2010-09-15
ITMI20012135A1 (it) 2003-04-16
US20040247627A1 (en) 2004-12-09
CA2463681A1 (en) 2003-04-24
US8178121B2 (en) 2012-05-15
WO2003033026A1 (en) 2003-04-24
DK1465663T3 (da) 2008-05-13
AU2002342826B2 (en) 2006-09-07
NZ532936A (en) 2007-04-27
CN1571678A (zh) 2005-01-26

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