PT1332137E - Tratamento de tumores estromais gastrintestinais - Google Patents
Tratamento de tumores estromais gastrintestinaisInfo
- Publication number
- PT1332137E PT1332137E PT01988712T PT01988712T PT1332137E PT 1332137 E PT1332137 E PT 1332137E PT 01988712 T PT01988712 T PT 01988712T PT 01988712 T PT01988712 T PT 01988712T PT 1332137 E PT1332137 E PT 1332137E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- gastrintestinal
- stromal tumors
- methylpiperazin
- ylamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Farming Of Fish And Shellfish (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24381000P | 2000-10-27 | 2000-10-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1332137E true PT1332137E (pt) | 2006-07-31 |
Family
ID=22920224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT01988712T PT1332137E (pt) | 2000-10-27 | 2001-10-26 | Tratamento de tumores estromais gastrintestinais |
Country Status (26)
Country | Link |
---|---|
US (1) | US6958335B2 (pt) |
EP (1) | EP1332137B1 (pt) |
JP (1) | JP4386635B2 (pt) |
KR (1) | KR100885129B1 (pt) |
CN (1) | CN1276754C (pt) |
AT (1) | ATE321556T1 (pt) |
AU (2) | AU1826202A (pt) |
BR (1) | BRPI0114870B8 (pt) |
CA (1) | CA2424470C (pt) |
CY (1) | CY1105055T1 (pt) |
CZ (1) | CZ303944B6 (pt) |
DE (1) | DE60118430T2 (pt) |
DK (1) | DK1332137T3 (pt) |
ES (1) | ES2260317T3 (pt) |
HK (1) | HK1058193A1 (pt) |
HU (1) | HU229106B1 (pt) |
IL (2) | IL155029A0 (pt) |
MX (1) | MXPA03003703A (pt) |
NO (1) | NO324948B1 (pt) |
NZ (1) | NZ525254A (pt) |
PL (1) | PL209733B1 (pt) |
PT (1) | PT1332137E (pt) |
RU (1) | RU2301066C2 (pt) |
SK (1) | SK287335B6 (pt) |
WO (1) | WO2002034727A2 (pt) |
ZA (1) | ZA200302155B (pt) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL392652A1 (pl) * | 2001-05-16 | 2010-12-06 | Novartis Ag | Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację |
ATE343415T1 (de) * | 2001-06-29 | 2006-11-15 | Ab Science | Die verwendung von c-kit hemmer zur behandlung von entzündlichen darmerkrankungen |
EP1401413B1 (en) * | 2001-06-29 | 2006-11-22 | AB Science | Use of tyrosine kinase inhibitions for treating allergic diseases |
ATE330608T1 (de) * | 2001-06-29 | 2006-07-15 | Ab Science | Die verwendung von n-phenyl-2-pyrimidine-amine derivaten zur behandlung von entzündlichen erkrankungen |
CA2452368A1 (en) * | 2001-06-29 | 2003-01-09 | Ab Science | New potent, selective and non toxic c-kit inhibitors |
EP1401412A2 (en) * | 2001-06-29 | 2004-03-31 | AB Science | Use of potent, selective and non toxic c-kit inhibitors for treating tumor angiogenesis |
DE60228278D1 (de) * | 2001-09-20 | 2008-09-25 | Ab Science | Die verwendung von potenten, selektiven und nontoxischen c-kithemmern zur behandlung von interstitieller blasenentzündung |
EP1461032B1 (en) * | 2001-09-20 | 2008-07-16 | AB Science | Use of c-kit inhibitors for promoting hair growth |
ATE334693T1 (de) * | 2002-02-27 | 2006-08-15 | Ab Science | Verwendung von tyrosine-kinase inhibitoren zur behandlung von cns krankheiten |
FR2844452A1 (fr) * | 2002-09-18 | 2004-03-19 | Inst Gustave Roussy Igr | Utilisation d'inhibiteurs specifiques de tyrosine kinases pour l'immunomodulation |
US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
CN100467064C (zh) * | 2003-09-19 | 2009-03-11 | 诺瓦提斯公司 | 伊马替尼和米哚妥林在制备治疗胃肠道基质肿瘤药物中的应用 |
US20100210596A1 (en) * | 2006-02-01 | 2010-08-19 | Bluestone Jeffrey A | Use of aminopyrimidine compounds in the treatment of immune disorders |
JP2010502743A (ja) * | 2006-09-11 | 2010-01-28 | キュリス,インコーポレイテッド | 抗増殖薬剤としての多機能性低分子 |
AU2007296743B2 (en) * | 2006-09-11 | 2012-02-16 | Curis, Inc. | Tyrosine kinase inhibitors containing a zinc binding moiety |
US8642067B2 (en) | 2007-04-02 | 2014-02-04 | Allergen, Inc. | Methods and compositions for intraocular administration to treat ocular conditions |
US20090082361A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched imatinib |
CN101584696A (zh) | 2008-05-21 | 2009-11-25 | 上海艾力斯医药科技有限公司 | 包含喹唑啉衍生物的组合物及制备方法、用途 |
US8530492B2 (en) | 2009-04-17 | 2013-09-10 | Nektar Therapeutics | Oligomer-protein tyrosine kinase inhibitor conjugates |
KR20200003933A (ko) | 2011-03-04 | 2020-01-10 | 뉴젠 세러퓨틱스 인코포레이티드 | 알킨 치환된 퀴나졸린 화합물 및 그것의 사용 방법 |
WO2012155339A1 (zh) | 2011-05-17 | 2012-11-22 | 江苏康缘药业股份有限公司 | 4-苯胺-6-丁烯酰胺-7-烷醚喹唑啉衍生物及其制备方法和用途 |
IN2014DN07898A (pt) | 2012-02-21 | 2015-04-24 | Ranbaxy Lab Ltd | |
US8461179B1 (en) | 2012-06-07 | 2013-06-11 | Deciphera Pharmaceuticals, Llc | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
AU2013295549B2 (en) | 2012-07-27 | 2018-04-19 | Izumi Technology, Llc | Efflux inhibitor compositions and methods of treatment using the same |
WO2015017728A1 (en) | 2013-07-31 | 2015-02-05 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
US11285152B2 (en) | 2017-07-20 | 2022-03-29 | Kashiv Biosciences, Llc | Stable oral pharmaceutical composition of imatinib |
CA3089630A1 (en) | 2018-01-31 | 2019-08-08 | Deciphera Pharmaceuticals, Llc | Combination therapy for the treatment of mastocytosis |
SG11202007198WA (en) | 2018-01-31 | 2020-08-28 | Deciphera Pharmaceuticals Llc | Combination therapy for the treatment of gastrointestinal stromal tumors |
US20220354951A1 (en) | 2019-08-02 | 2022-11-10 | Onehealthcompany, Inc. | Treatment of Canine Cancers |
MX2022001863A (es) | 2019-08-12 | 2022-05-30 | Deciphera Pharmaceuticals Llc | Metodos para tratar los tumores del estroma gastrointestinal. |
TW202122082A (zh) | 2019-08-12 | 2021-06-16 | 美商迪賽孚爾製藥有限公司 | 治療胃腸道基質瘤方法 |
KR20220123058A (ko) | 2019-12-30 | 2022-09-05 | 데시페라 파마슈티칼스, 엘엘씨. | 1-(4-브로모-5-(1-에틸-7-(메틸아미노)-2-옥소-1,2-디히드로-1,6-나프티리딘-3-일)-2-플루오로페닐)-3-페닐우레아의 조성물 |
DK4084778T3 (da) | 2019-12-30 | 2023-12-11 | Deciphera Pharmaceuticals Llc | Amorfe kinaseinhibitorformuleringer og fremgangsmåder til anvendelse deraf |
KR102535840B1 (ko) | 2020-07-31 | 2023-05-23 | (주)파로스아이바이오 | 2,3,5-치환된 싸이오펜 화합물의 위장관기질종양 예방, 개선 또는 치료 용도 |
US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW225528B (pt) * | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
EP1117397A1 (en) * | 1998-08-31 | 2001-07-25 | Sugen, Inc. | Geometrically restricted 2-indolinone derivatives as modulators of protein kinase activity |
-
2001
- 2001-10-26 KR KR1020037003903A patent/KR100885129B1/ko active IP Right Review Request
- 2001-10-26 EP EP01988712A patent/EP1332137B1/en not_active Expired - Lifetime
- 2001-10-26 CZ CZ20031152A patent/CZ303944B6/cs not_active IP Right Cessation
- 2001-10-26 BR BR0114870-2 patent/BRPI0114870B8/pt active IP Right Grant
- 2001-10-26 DE DE60118430T patent/DE60118430T2/de not_active Expired - Lifetime
- 2001-10-26 WO PCT/EP2001/012442 patent/WO2002034727A2/en active IP Right Grant
- 2001-10-26 MX MXPA03003703A patent/MXPA03003703A/es active IP Right Grant
- 2001-10-26 PT PT01988712T patent/PT1332137E/pt unknown
- 2001-10-26 IL IL15502901A patent/IL155029A0/xx unknown
- 2001-10-26 RU RU2003114752/15A patent/RU2301066C2/ru not_active IP Right Cessation
- 2001-10-26 JP JP2002537718A patent/JP4386635B2/ja not_active Expired - Lifetime
- 2001-10-26 SK SK518-2003A patent/SK287335B6/sk not_active IP Right Cessation
- 2001-10-26 CN CNB018178952A patent/CN1276754C/zh not_active Ceased
- 2001-10-26 AU AU1826202A patent/AU1826202A/xx active Pending
- 2001-10-26 US US10/415,015 patent/US6958335B2/en not_active Expired - Lifetime
- 2001-10-26 AT AT01988712T patent/ATE321556T1/de active
- 2001-10-26 PL PL362148A patent/PL209733B1/pl unknown
- 2001-10-26 HU HU0301512A patent/HU229106B1/hu unknown
- 2001-10-26 ES ES01988712T patent/ES2260317T3/es not_active Expired - Lifetime
- 2001-10-26 AU AU2002218262A patent/AU2002218262B2/en not_active Expired
- 2001-10-26 CA CA002424470A patent/CA2424470C/en not_active Expired - Lifetime
- 2001-10-26 DK DK01988712T patent/DK1332137T3/da active
- 2001-10-26 NZ NZ525254A patent/NZ525254A/en not_active IP Right Cessation
-
2003
- 2003-03-18 ZA ZA200302155A patent/ZA200302155B/en unknown
- 2003-03-20 IL IL155029A patent/IL155029A/en active IP Right Grant
- 2003-04-24 NO NO20031833A patent/NO324948B1/no not_active IP Right Cessation
- 2003-12-29 HK HK03109439A patent/HK1058193A1/xx not_active IP Right Cessation
-
2006
- 2006-06-21 CY CY20061100839T patent/CY1105055T1/el unknown
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