PT1322651E - Compostos heteroaromáticos bicíclicos - Google Patents

Compostos heteroaromáticos bicíclicos Download PDF

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Publication number
PT1322651E
PT1322651E PT01982306T PT01982306T PT1322651E PT 1322651 E PT1322651 E PT 1322651E PT 01982306 T PT01982306 T PT 01982306T PT 01982306 T PT01982306 T PT 01982306T PT 1322651 E PT1322651 E PT 1322651E
Authority
PT
Portugal
Prior art keywords
heteroaromatic compounds
bicyclic heteroaromatic
bicyclic
compounds
heteroaromatic
Prior art date
Application number
PT01982306T
Other languages
English (en)
Inventor
Cornelis Marius Timmers
Willem Frederik Johan Karstens
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of PT1322651E publication Critical patent/PT1322651E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT01982306T 2000-09-22 2001-09-17 Compostos heteroaromáticos bicíclicos PT1322651E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00203287 2000-09-22

Publications (1)

Publication Number Publication Date
PT1322651E true PT1322651E (pt) 2008-02-28

Family

ID=8172046

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01982306T PT1322651E (pt) 2000-09-22 2001-09-17 Compostos heteroaromáticos bicíclicos

Country Status (32)

Country Link
US (2) US7229990B2 (pt)
EP (2) EP1886999A3 (pt)
JP (1) JP4977940B2 (pt)
KR (1) KR100860040B1 (pt)
CN (1) CN1247594C (pt)
AR (1) AR030784A1 (pt)
AT (1) ATE384726T1 (pt)
AU (2) AU1392902A (pt)
BR (1) BR0113987A (pt)
CA (1) CA2422054C (pt)
CY (1) CY1107308T1 (pt)
CZ (1) CZ297136B6 (pt)
DE (1) DE60132607T2 (pt)
DK (1) DK1322651T3 (pt)
EC (1) ECSP034523A (pt)
ES (1) ES2299524T3 (pt)
HK (1) HK1054942A1 (pt)
HR (1) HRP20030220B1 (pt)
HU (1) HU229422B1 (pt)
IL (2) IL154624A0 (pt)
IS (1) IS2531B (pt)
MX (1) MXPA03002478A (pt)
NO (1) NO328683B1 (pt)
NZ (1) NZ524444A (pt)
PE (1) PE20020537A1 (pt)
PL (1) PL207755B1 (pt)
PT (1) PT1322651E (pt)
RU (1) RU2271360C2 (pt)
SK (1) SK287554B6 (pt)
TW (1) TWI290143B (pt)
WO (1) WO2002024703A1 (pt)
ZA (1) ZA200301588B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1886999A3 (en) * 2000-09-22 2008-03-12 N.V. Organon Bicyclic heteroaromatic compounds
TW200407127A (en) 2002-08-21 2004-05-16 Astrazeneca Ab Chemical compounds
US7674822B2 (en) 2004-11-24 2010-03-09 Wyeth PTP1b inhibitors
WO2006124490A2 (en) * 2005-05-17 2006-11-23 Schering Corporation Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
AU2007254165A1 (en) * 2006-05-17 2007-11-29 Forschungsverbund Berlin E.V. Pyrimidine low molecular weight ligands for modulating hormone receptors
EP2280969A1 (en) 2008-04-29 2011-02-09 F. Hoffmann-La Roche AG Pyrimidinyl pyridone inhibitors of jnk.
JP5718233B2 (ja) 2008-10-20 2015-05-13 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 甲状腺刺激ホルモン受容体(tshr)の低分子量アゴニスト
JP5965387B2 (ja) 2010-04-08 2016-08-03 アメリカ合衆国 Tsh受容体用のインバースアゴニストおよびニュートラルアンタゴニスト
WO2013028818A1 (en) * 2011-08-23 2013-02-28 Endo Pharmaceuticals Inc. Pyrimido- pyridazinone compounds and use thereof
CN113680386B (zh) * 2021-08-23 2023-08-11 深圳湾实验室坪山生物医药研发转化中心 氮杂环卡宾-方酰胺双功能催化剂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL181895B1 (pl) * 1994-06-16 2001-10-31 Pfizer Nowe pirazolo-i pirolopirydyny _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ PL PL PL PL
EP0920319A4 (en) * 1996-05-20 2002-05-02 Merck & Co Inc GONADOLIBERIN ANTAGONISTS
TW564247B (en) * 1999-04-08 2003-12-01 Akzo Nobel Nv Bicyclic heteraromatic compound
EP1886999A3 (en) * 2000-09-22 2008-03-12 N.V. Organon Bicyclic heteroaromatic compounds

Also Published As

Publication number Publication date
IL154624A0 (en) 2003-09-17
EP1886999A2 (en) 2008-02-13
SK3312003A3 (en) 2003-08-05
NO328683B1 (no) 2010-04-26
CZ2003828A3 (cs) 2003-08-13
CN1462273A (zh) 2003-12-17
DE60132607D1 (de) 2008-03-13
EP1322651B1 (en) 2008-01-23
AU1392902A (en) 2002-04-02
KR20030040483A (ko) 2003-05-22
IS2531B (is) 2009-07-15
HK1054942A1 (en) 2003-12-19
EP1886999A3 (en) 2008-03-12
MXPA03002478A (es) 2004-05-05
ES2299524T3 (es) 2008-06-01
HUP0302648A2 (hu) 2003-11-28
US7229990B2 (en) 2007-06-12
ATE384726T1 (de) 2008-02-15
SK287554B6 (sk) 2011-01-04
DE60132607T2 (de) 2009-01-29
PL360675A1 (en) 2004-09-20
HRP20030220B1 (en) 2011-10-31
US20070197527A1 (en) 2007-08-23
JP4977940B2 (ja) 2012-07-18
CY1107308T1 (el) 2012-11-21
AR030784A1 (es) 2003-09-03
BR0113987A (pt) 2003-08-12
DK1322651T3 (da) 2008-06-02
NZ524444A (en) 2004-03-26
PE20020537A1 (es) 2002-06-20
US20030225113A1 (en) 2003-12-04
PL207755B1 (pl) 2011-01-31
CA2422054A1 (en) 2002-03-28
NO20031314L (no) 2003-03-21
KR100860040B1 (ko) 2008-09-25
CN1247594C (zh) 2006-03-29
WO2002024703A1 (en) 2002-03-28
ECSP034523A (es) 2003-04-25
IS6732A (is) 2003-02-28
AU2002213929B2 (en) 2006-04-13
NO20031314D0 (no) 2003-03-21
RU2271360C2 (ru) 2006-03-10
EP1322651A1 (en) 2003-07-02
HRP20030220A2 (en) 2003-06-30
US7618963B2 (en) 2009-11-17
HU229422B1 (hu) 2013-12-30
IL154624A (en) 2009-09-01
CA2422054C (en) 2011-01-11
JP2004509896A (ja) 2004-04-02
CZ297136B6 (cs) 2006-09-13
EP1886999A8 (en) 2010-08-04
HUP0302648A3 (en) 2004-11-29
TWI290143B (en) 2007-11-21
ZA200301588B (en) 2004-06-22

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