HRP20030220B1 - Bicyclic heteroaromatic compounds - Google Patents

Bicyclic heteroaromatic compounds

Info

Publication number
HRP20030220B1
HRP20030220B1 HR20030220A HRP20030220A HRP20030220B1 HR P20030220 B1 HRP20030220 B1 HR P20030220B1 HR 20030220 A HR20030220 A HR 20030220A HR P20030220 A HRP20030220 A HR P20030220A HR P20030220 B1 HRP20030220 B1 HR P20030220B1
Authority
HR
Croatia
Prior art keywords
bicyclic heteroaromatic
heteroaromatic compounds
thieno
methylthio
carboxamide
Prior art date
Application number
HR20030220A
Other languages
English (en)
Croatian (hr)
Inventor
Marius Timmers Cornelis
Frederik Johan Karstens Willem
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of HRP20030220A2 publication Critical patent/HRP20030220A2/hr
Publication of HRP20030220B1 publication Critical patent/HRP20030220B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20030220A 2000-09-22 2003-03-21 Bicyclic heteroaromatic compounds HRP20030220B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00203287 2000-09-22
PCT/EP2001/010743 WO2002024703A1 (en) 2000-09-22 2001-09-17 Bicyclic heteroaromatic compounds

Publications (2)

Publication Number Publication Date
HRP20030220A2 HRP20030220A2 (en) 2003-06-30
HRP20030220B1 true HRP20030220B1 (en) 2011-10-31

Family

ID=8172046

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030220A HRP20030220B1 (en) 2000-09-22 2003-03-21 Bicyclic heteroaromatic compounds

Country Status (32)

Country Link
US (2) US7229990B2 (xx)
EP (2) EP1886999A3 (xx)
JP (1) JP4977940B2 (xx)
KR (1) KR100860040B1 (xx)
CN (1) CN1247594C (xx)
AR (1) AR030784A1 (xx)
AT (1) ATE384726T1 (xx)
AU (2) AU2002213929B2 (xx)
BR (1) BR0113987A (xx)
CA (1) CA2422054C (xx)
CY (1) CY1107308T1 (xx)
CZ (1) CZ297136B6 (xx)
DE (1) DE60132607T2 (xx)
DK (1) DK1322651T3 (xx)
EC (1) ECSP034523A (xx)
ES (1) ES2299524T3 (xx)
HK (1) HK1054942A1 (xx)
HR (1) HRP20030220B1 (xx)
HU (1) HU229422B1 (xx)
IL (2) IL154624A0 (xx)
IS (1) IS2531B (xx)
MX (1) MXPA03002478A (xx)
NO (1) NO328683B1 (xx)
NZ (1) NZ524444A (xx)
PE (1) PE20020537A1 (xx)
PL (1) PL207755B1 (xx)
PT (1) PT1322651E (xx)
RU (1) RU2271360C2 (xx)
SK (1) SK287554B6 (xx)
TW (1) TWI290143B (xx)
WO (1) WO2002024703A1 (xx)
ZA (1) ZA200301588B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60132607T2 (de) * 2000-09-22 2009-01-29 N.V. Organon Bicyclische heteroaromatische verbindungen
TW200407127A (en) 2002-08-21 2004-05-16 Astrazeneca Ab Chemical compounds
US7674822B2 (en) 2004-11-24 2010-03-09 Wyeth PTP1b inhibitors
US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
US7723342B2 (en) * 2005-05-17 2010-05-25 Schering Corporation Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
WO2007136776A2 (en) * 2006-05-17 2007-11-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pyrimidine low molecular weight ligands for modulating hormone receptors
JP5302389B2 (ja) 2008-04-29 2013-10-02 エフ．ホフマン−ラ ロシュ アーゲー Ｊｎｋのピリミジニルピリドンインヒビター
WO2010047674A1 (en) 2008-10-20 2010-04-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Low molecular weight thyroid stimulating hormone receptor (tshr) agonists
CA2789818A1 (en) 2010-04-08 2011-10-13 The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services Inverse agonists and neutral antagonists for the tsh receptor
FI3392252T3 (fi) * 2011-08-23 2024-01-08 Libertas Bio Inc Pyrimidopyridazinoniyhdisteet ja niiden käyttö
CN113680386B (zh) * 2021-08-23 2023-08-11 深圳湾实验室坪山生物医药研发转化中心 氮杂环卡宾-方酰胺双功能催化剂及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034563A1 (en) * 1994-06-16 1995-12-21 Pfizer Inc. Pyrazolo and pyrrolopyridines
WO2000061586A1 (en) * 1999-04-08 2000-10-19 Akzo Nobel N.V. Bicyclic heteroaromatic compounds useful as lh agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2254974A1 (en) * 1996-05-20 1997-11-27 Mark Goulet Antagonists of gonadotropin releasing hormone
DE60132607T2 (de) * 2000-09-22 2009-01-29 N.V. Organon Bicyclische heteroaromatische verbindungen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034563A1 (en) * 1994-06-16 1995-12-21 Pfizer Inc. Pyrazolo and pyrrolopyridines
WO2000061586A1 (en) * 1999-04-08 2000-10-19 Akzo Nobel N.V. Bicyclic heteroaromatic compounds useful as lh agonists

Also Published As

Publication number Publication date
KR20030040483A (ko) 2003-05-22
HU229422B1 (hu) 2013-12-30
DE60132607T2 (de) 2009-01-29
US7618963B2 (en) 2009-11-17
DE60132607D1 (de) 2008-03-13
HUP0302648A2 (hu) 2003-11-28
IL154624A (en) 2009-09-01
EP1322651B1 (en) 2008-01-23
ECSP034523A (es) 2003-04-25
PL360675A1 (en) 2004-09-20
AU2002213929B2 (en) 2006-04-13
CA2422054C (en) 2011-01-11
ES2299524T3 (es) 2008-06-01
WO2002024703A1 (en) 2002-03-28
PE20020537A1 (es) 2002-06-20
CY1107308T1 (el) 2012-11-21
EP1886999A2 (en) 2008-02-13
SK3312003A3 (en) 2003-08-05
CN1247594C (zh) 2006-03-29
US20030225113A1 (en) 2003-12-04
EP1886999A3 (en) 2008-03-12
JP4977940B2 (ja) 2012-07-18
DK1322651T3 (da) 2008-06-02
NO20031314D0 (no) 2003-03-21
KR100860040B1 (ko) 2008-09-25
TWI290143B (en) 2007-11-21
PL207755B1 (pl) 2011-01-31
HUP0302648A3 (en) 2004-11-29
IL154624A0 (en) 2003-09-17
EP1886999A8 (en) 2010-08-04
HRP20030220A2 (en) 2003-06-30
MXPA03002478A (es) 2004-05-05
CZ297136B6 (cs) 2006-09-13
CN1462273A (zh) 2003-12-17
HK1054942A1 (en) 2003-12-19
NZ524444A (en) 2004-03-26
US20070197527A1 (en) 2007-08-23
RU2271360C2 (ru) 2006-03-10
ATE384726T1 (de) 2008-02-15
ZA200301588B (en) 2004-06-22
IS6732A (is) 2003-02-28
SK287554B6 (sk) 2011-01-04
AR030784A1 (es) 2003-09-03
CZ2003828A3 (cs) 2003-08-13
PT1322651E (pt) 2008-02-28
EP1322651A1 (en) 2003-07-02
IS2531B (is) 2009-07-15
JP2004509896A (ja) 2004-04-02
BR0113987A (pt) 2003-08-12
NO20031314L (no) 2003-03-21
US7229990B2 (en) 2007-06-12
CA2422054A1 (en) 2002-03-28
NO328683B1 (no) 2010-04-26
AU1392902A (en) 2002-04-02

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: N.V. ORGANON, NL

B1PR Patent granted
PPPP Transfer of rights

Owner name: MSD OSS B.V., NL

PPPP Transfer of rights

Owner name: ORGANON BIOSCIENCES NEDERLAND B.V., NL

ODRP Renewal fee for the maintenance of a patent

Payment date: 20140826

Year of fee payment: 14

PBON Lapse due to non-payment of renewal fee

Effective date: 20150917