PT1214097E - Ácidos nucleicos que codificam polipéptidos de poliepitopos - Google Patents

Ácidos nucleicos que codificam polipéptidos de poliepitopos Download PDF

Info

Publication number
PT1214097E
PT1214097E PT00965119T PT00965119T PT1214097E PT 1214097 E PT1214097 E PT 1214097E PT 00965119 T PT00965119 T PT 00965119T PT 00965119 T PT00965119 T PT 00965119T PT 1214097 E PT1214097 E PT 1214097E
Authority
PT
Portugal
Prior art keywords
nucleic acids
acids encoding
polyepitope polypeptides
encoding polyepitope
polypeptides
Prior art date
Application number
PT00965119T
Other languages
English (en)
Inventor
Mary Lynne Hedley
Robert C Urban
Roman M Chicz
Original Assignee
Eisai Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Inc filed Critical Eisai Inc
Publication of PT1214097E publication Critical patent/PT1214097E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT00965119T 1999-09-16 2000-09-18 Ácidos nucleicos que codificam polipéptidos de poliepitopos PT1214097E (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15466599P 1999-09-16 1999-09-16
US39853499A 1999-09-16 1999-09-16
US16984699P 1999-12-09 1999-12-09
US45817399A 1999-12-09 1999-12-09

Publications (1)

Publication Number Publication Date
PT1214097E true PT1214097E (pt) 2009-10-19

Family

ID=27496146

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00965119T PT1214097E (pt) 1999-09-16 2000-09-18 Ácidos nucleicos que codificam polipéptidos de poliepitopos

Country Status (10)

Country Link
EP (2) EP1214097B3 (pt)
JP (1) JP2003509035A (pt)
AU (1) AU785319B2 (pt)
CA (1) CA2384987A1 (pt)
CY (1) CY1109699T1 (pt)
DE (1) DE60042556D1 (pt)
DK (1) DK1214097T3 (pt)
ES (1) ES2330078T3 (pt)
PT (1) PT1214097E (pt)
WO (1) WO2001019408A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057069A2 (en) * 2000-02-02 2001-08-09 Transgene S.A. Targeting peptides
FR2824326B1 (fr) * 2001-05-04 2004-03-19 Commissariat Energie Atomique Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications
GB0118532D0 (en) 2001-07-30 2001-09-19 Isis Innovation Materials and methods relating to improved vaccination strategies
WO2003063770A2 (en) 2001-11-07 2003-08-07 Mannkind Corporation Expression vectors encoding epitopes of target-associated antigens and methods for their design
AU2003229429A1 (en) * 2002-05-07 2003-11-11 Aventis Pasteur, Ltd. Polyepitopes and mini-genes for cancer treatment
AU2002950183A0 (en) * 2002-07-12 2002-09-12 The Council Of The Queensland Institute Of Medical Research Expression of hydrophobic proteins
JP2006503914A (ja) * 2002-10-21 2006-02-02 エムジーアイ ファーマ バイオロジックス インコーポレイテッド ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法
ATE520708T1 (de) 2003-03-28 2011-09-15 Us Gov Health & Human Serv Immunogenetische hiv-1 multi-klade, multivalente konstrukte und deren verwendung
BRPI0411127A (pt) * 2003-06-10 2006-05-23 Univ Melbourne composição de matéria para modulação de resposta imuno num sujeito a um antìgeno alvo e respectivos método de modulação, processo de produção de células de apresentação de antìgeno e método de tratamento e/ou profilaxia de doença ou condição associada à presença de antìgeno alvo de interesse
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
WO2009129227A1 (en) 2008-04-17 2009-10-22 Pds Biotechnology Corporation Stimulation of an immune response by enantiomers of cationic lipids
EA025280B1 (ru) * 2010-03-09 2016-12-30 Амир Максютов Полиэпитопные конструкции и способы их получения и применения
CN105463001A (zh) * 2010-08-13 2016-04-06 株式会社吉耐森 用于预防或治疗宫颈癌的、包含人乳头瘤病毒变形体及免疫增强剂的组合物
US9000139B2 (en) 2010-08-13 2015-04-07 Genexine, Inc. Composition for preventing or treating cervical cancer having human papillomavirus plasmodium and immunity enhancer
CN105463000B (zh) * 2010-08-13 2021-06-01 株式会社吉耐森 用于预防或治疗宫颈癌的、包含人乳头瘤病毒变形体及免疫增强剂的组合物
AU2012261237B2 (en) 2011-05-24 2017-06-01 BioNTech SE Individualized vaccines for cancer
SI2714071T1 (sl) 2011-05-24 2019-11-29 Biontech Rna Pharmaceuticals Gmbh Individualizirana cepiva proti raku
EP4091630A1 (en) 2012-09-21 2022-11-23 PDS Biotechnology Corporation Vaccines comprising r-dotap
EP3193905B1 (en) 2014-08-15 2024-04-03 Genexine, Inc. Compositions for use in treating cervical cancer
EA035461B1 (ru) * 2014-11-04 2020-06-19 Янссен Вэксинс Энд Превеншн Б.В. Терапевтические вакцины против hpv16
EP4092112A1 (en) 2015-11-13 2022-11-23 PDS Biotechnology Corporation Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy
AU2016367712B2 (en) 2015-12-09 2021-10-07 Jingang Medicine (Australia) Pty Ltd Immunomodulating composition for treatment
JP7165652B2 (ja) * 2016-10-05 2022-11-04 ピーディーエス バイオテクノロジー コーポレイション 新規ｈｐｖ１６非ｈｌａ拘束性ｔ細胞ワクチン、その組成物及び使用方法
MX2019007924A (es) * 2016-12-28 2020-01-27 Invvax Inc Vacunas contra la influenza.
US20210393757A1 (en) * 2018-10-01 2021-12-23 The Wistar Institute Melanoma Canine Vaccine Compositions and Methods of Use Thereof
JP7460094B2 (ja) 2020-04-24 2024-04-02 ジェネクシン・インコーポレイテッド 子宮頸がんの治療方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502760A (ja) * 1988-10-03 1992-05-21 レプリゲン・コーポレーション エイズの診断，予防および治療に有効な新規ｈｉｖ蛋白質およびペプチド
PT97073A (pt) * 1990-03-20 1991-10-31 Behringwerke Ag Processo para a preparacao de epitopos soro-reactivos de proteinas de papillomavirus 16 humano (hpv)
US5753233A (en) * 1990-05-10 1998-05-19 Behring Diagnostics Gmbh Seroreactive epitopes on proteins of human papilloma-virus (HPV) 18
DE4015044A1 (de) * 1990-05-10 1991-11-14 Behringwerke Ag Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
AU8762991A (en) * 1990-09-26 1992-04-15 Bristol-Myers Squibb Company Human papilloma viral protein expression for use in vaccine compositions
GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
ES2193133T3 (es) * 1991-07-13 2003-11-01 Dade Behring Marburg Gmbh Uso de peptidos derivados de los genes e6 y e7 de hpv-16 para fines.
IL105554A (en) * 1992-05-05 1999-08-17 Univ Leiden Peptides of human papillomavirus for use in preparations elicit a human T cell response
DE69332485T2 (de) 1992-08-11 2003-11-13 Harvard College Immunmodulierende peptide
US5679509A (en) * 1993-09-28 1997-10-21 University Of New Mexico Methods and a diagnostic aid for distinguishing a subset of HPV that is associated with an increased risk of developing cervical dysplasia and cervical cancer
AU710504B2 (en) 1994-03-15 1999-09-23 Brown University Research Foundation Polymeric gene delivery system
AUPN015794A0 (en) * 1994-12-20 1995-01-19 Csl Limited Variants of human papilloma virus antigens
US5783567A (en) 1997-01-22 1998-07-21 Pangaea Pharmaceuticals, Inc. Microparticles for delivery of nucleic acid
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein

Also Published As

Publication number Publication date
EP1214097B3 (en) 2011-07-20
EP2100620A1 (en) 2009-09-16
WO2001019408A9 (en) 2002-12-05
DE60042556D1 (de) 2011-02-10
EP1214097A4 (en) 2005-02-02
CA2384987A1 (en) 2001-03-22
AU7589100A (en) 2001-04-17
JP2003509035A (ja) 2003-03-11
CY1109699T1 (el) 2014-08-13
DK1214097T3 (da) 2009-11-16
EP1214097B1 (en) 2009-07-15
WO2001019408A1 (en) 2001-03-22
ES2330078T3 (es) 2009-12-04
EP1214097B9 (en) 2010-05-19
EP1214097A1 (en) 2002-06-19
AU785319B2 (en) 2007-01-11

Similar Documents

Publication Publication Date Title
EP1214097A4 (en) NUCLEIC ACIDS ENCODING POLYEPITOPES POLYPEPTIDES
EP1242443A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
AU2001234944A8 (en) Novel nucleic acids and polypeptides
EP1325120A4 (en) NUCLEIC ACIDS AND POLYPEPTIDES
EP1490386A4 (en) NEW POLYPEPTIDES AND THESE ENCODING NUCLEIC ACIDS
EP1504099A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
EP1381621A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
EP1432800A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
EP1470238A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
EP1341804A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
AU2001291649A1 (en) Nucleic acids encoding polypeptides having proteolytic activity
AU2001248284A1 (en) Nucleic acids encoding polypeptides having haloperoxidase activity
AU2001246407A1 (en) Nucleic acids encoding polypeptides having haloperoxidase activity
AU2001246405A1 (en) Nucleic acids encoding polypeptides having haloperoxidase activity
AU2001246406A1 (en) Nucleic acids encoding polypeptides having haloperoxidase activity
EP1430112A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
EP1276751A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
EP1368475A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
AU1181802A (en) Novel proteins and nucleic acids encoding same
EP1341803A4 (en) NEW NUCLEIC ACIDS AND POLYPEPTIDES
AU2001239889A1 (en) Polypeptides and nucleic acids encoding same
IL145785A0 (en) Novel chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same
HK1049352A1 (zh) 一種新穎的脫氧核糖核酸編碼多肽prost-ets
AU1453601A (en) Novel polypeptides and nucleic acids encoding same
AU2001263005A8 (en) Novel nucleic acids and polypeptides