PT1173413E - Utilizacao de derivados do acido 2,4-diamino-3-hidroxicarboxilicos como inibidores de proteassoma - Google Patents
Utilizacao de derivados do acido 2,4-diamino-3-hidroxicarboxilicos como inibidores de proteassomaInfo
- Publication number
- PT1173413E PT1173413E PT00927038T PT00927038T PT1173413E PT 1173413 E PT1173413 E PT 1173413E PT 00927038 T PT00927038 T PT 00927038T PT 00927038 T PT00927038 T PT 00927038T PT 1173413 E PT1173413 E PT 1173413E
- Authority
- PT
- Portugal
- Prior art keywords
- substituted
- alkyl
- unsubstituted
- arylalkyl
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30077999A | 1999-04-27 | 1999-04-27 | |
| US38870099A | 1999-09-02 | 1999-09-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1173413E true PT1173413E (pt) | 2004-10-29 |
Family
ID=26971977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00927038T PT1173413E (pt) | 1999-04-27 | 2000-04-25 | Utilizacao de derivados do acido 2,4-diamino-3-hidroxicarboxilicos como inibidores de proteassoma |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20050026994A1 (pt) |
| EP (1) | EP1173413B1 (pt) |
| JP (1) | JP2002543058A (pt) |
| CN (1) | CN100357267C (pt) |
| AT (1) | ATE270268T1 (pt) |
| AU (1) | AU4555800A (pt) |
| BR (1) | BR0010134A (pt) |
| CA (1) | CA2370830C (pt) |
| DE (1) | DE60011889T2 (pt) |
| ES (1) | ES2223512T3 (pt) |
| HK (1) | HK1044931A1 (pt) |
| PT (1) | PT1173413E (pt) |
| WO (1) | WO2000064863A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU49055B (sh) | 1996-04-25 | 2003-08-29 | Milenko dipl.ing. Pupović | Sto za nameštanje kičme |
| GB0012795D0 (en) * | 2000-05-25 | 2000-07-19 | Novartis Ag | Organic compounds |
| BR0209965A (pt) | 2001-05-21 | 2004-04-06 | Alcon Inc | Uso de inibidores de nf-kappab para tratar distúrbios do olho seco |
| US7112588B2 (en) | 2001-05-21 | 2006-09-26 | Alcon, Inc. | Use of proteasome inhibitors to treat dry eye disorders |
| BR0209883A (pt) | 2001-05-21 | 2004-06-08 | Alcon Inc | Uso de inibidores da proteasoma para o tratamento de distúrbios do olho seco |
| US6872382B1 (en) | 2001-05-21 | 2005-03-29 | Alcon, Inc. | Use of selective PDE IV inhibitors to treat dry eye disorders |
| US6645994B1 (en) | 2001-06-01 | 2003-11-11 | Alcon, Inc. | Method of treating dry eye disorders |
| US7223745B2 (en) | 2003-08-14 | 2007-05-29 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| US7576206B2 (en) | 2003-08-14 | 2009-08-18 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| EP1637529A1 (en) * | 2004-09-20 | 2006-03-22 | 4Sc Ag | Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof |
| US7468383B2 (en) | 2005-02-11 | 2008-12-23 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| US8459852B2 (en) | 2007-10-05 | 2013-06-11 | Dental Equipment, Llc | LED-based dental exam lamp |
| CN102725300B (zh) | 2009-12-22 | 2015-03-11 | 赛福伦公司 | 蛋白酶体抑制剂及其制备、纯化、和应用的方法 |
| EP3591048A4 (en) * | 2017-01-31 | 2020-12-23 | Chugai Seiyaku Kabushiki Kaisha | PROCESS FOR SYNTHESIS OF PEPTIDES IN A CELL-FREE TRANSLATION SYSTEM |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5344634A (en) * | 1976-10-01 | 1978-04-21 | Kyowa Hakko Kogyo Co Ltd | Carcinostatic agent |
| MX9203836A (es) * | 1991-07-02 | 1993-01-01 | Sandoz Ag | Derivados de acido-4-amino-3-hidroxicarboxilico y proceso para su preparacion. |
| US5538997A (en) * | 1993-03-12 | 1996-07-23 | Sandoz Ltd. | 2,4-diamino-3-hydroxycarboxylic acid derivatives |
| DE4331135A1 (de) * | 1993-09-14 | 1995-03-16 | Bayer Ag | Neue antiviral wirksame valinhaltige Pseudopeptide |
-
2000
- 2000-04-25 CN CNB00807741XA patent/CN100357267C/zh not_active Expired - Fee Related
- 2000-04-25 AT AT00927038T patent/ATE270268T1/de not_active IP Right Cessation
- 2000-04-25 JP JP2000613816A patent/JP2002543058A/ja active Pending
- 2000-04-25 ES ES00927038T patent/ES2223512T3/es not_active Expired - Lifetime
- 2000-04-25 CA CA002370830A patent/CA2370830C/en not_active Expired - Fee Related
- 2000-04-25 AU AU45558/00A patent/AU4555800A/en not_active Abandoned
- 2000-04-25 PT PT00927038T patent/PT1173413E/pt unknown
- 2000-04-25 DE DE60011889T patent/DE60011889T2/de not_active Expired - Fee Related
- 2000-04-25 BR BR0010134-6A patent/BR0010134A/pt not_active Application Discontinuation
- 2000-04-25 EP EP00927038A patent/EP1173413B1/en not_active Expired - Lifetime
- 2000-04-25 WO PCT/EP2000/003688 patent/WO2000064863A1/en active IP Right Grant
-
2001
- 2001-10-25 US US10/035,301 patent/US20050026994A1/en not_active Abandoned
-
2002
- 2002-06-19 HK HK02104585A patent/HK1044931A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0010134A (pt) | 2002-01-15 |
| DE60011889D1 (en) | 2004-08-05 |
| CA2370830C (en) | 2009-10-13 |
| CN100357267C (zh) | 2007-12-26 |
| DE60011889T2 (de) | 2005-07-14 |
| EP1173413A1 (en) | 2002-01-23 |
| ATE270268T1 (de) | 2004-07-15 |
| WO2000064863A1 (en) | 2000-11-02 |
| US20050026994A1 (en) | 2005-02-03 |
| JP2002543058A (ja) | 2002-12-17 |
| AU4555800A (en) | 2000-11-10 |
| EP1173413B1 (en) | 2004-06-30 |
| HK1044931A1 (en) | 2002-11-08 |
| ES2223512T3 (es) | 2005-03-01 |
| CN1351587A (zh) | 2002-05-29 |
| CA2370830A1 (en) | 2000-11-02 |
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