PT1173176E - Utilizacao de sistemas policiclicos de 2-amino-tiazole para a preparacao de medicamentos para a profilaxia ou tratamento da obesidade - Google Patents
Utilizacao de sistemas policiclicos de 2-amino-tiazole para a preparacao de medicamentos para a profilaxia ou tratamento da obesidadeInfo
- Publication number
- PT1173176E PT1173176E PT00905028T PT00905028T PT1173176E PT 1173176 E PT1173176 E PT 1173176E PT 00905028 T PT00905028 T PT 00905028T PT 00905028 T PT00905028 T PT 00905028T PT 1173176 E PT1173176 E PT 1173176E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- obesity
- tiazole
- prophylaxis
- medicines
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical compound NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19908537A DE19908537A1 (de) | 1999-02-26 | 1999-02-26 | Verwendung von polycyclischen 2-Amino-Thiazol Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1173176E true PT1173176E (pt) | 2004-09-30 |
Family
ID=7899081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00905028T PT1173176E (pt) | 1999-02-26 | 2000-02-05 | Utilizacao de sistemas policiclicos de 2-amino-tiazole para a preparacao de medicamentos para a profilaxia ou tratamento da obesidade |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6476059B1 (https=) |
| EP (1) | EP1173176B1 (https=) |
| JP (1) | JP4728483B2 (https=) |
| KR (1) | KR20020002394A (https=) |
| CN (1) | CN1161120C (https=) |
| AT (1) | ATE267597T1 (https=) |
| AU (1) | AU766295B2 (https=) |
| BR (1) | BR0008557A (https=) |
| CA (1) | CA2362554A1 (https=) |
| DE (2) | DE19908537A1 (https=) |
| DK (1) | DK1173176T3 (https=) |
| ES (1) | ES2218122T3 (https=) |
| HK (1) | HK1045809B (https=) |
| PT (1) | PT1173176E (https=) |
| WO (1) | WO2000051602A1 (https=) |
| ZA (1) | ZA200106199B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19908538A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen |
| EP1816127A1 (en) * | 1999-04-22 | 2007-08-08 | H. Lundbeck A/S | Triazine derivatives for use as selective npy (y5) antagonists |
| AU2001246494A1 (en) * | 2000-03-03 | 2001-09-12 | Novartis Ag | Condensed thiazolamines and their use as neuropeptide y5 antagonists |
| US7732484B2 (en) * | 2000-08-01 | 2010-06-08 | University Of Virginia Patent Foundation | Use of selective adenosine A1 receptor allosteric enhancers to manipulate angiogenesis |
| JP2005529846A (ja) * | 2002-01-16 | 2005-10-06 | ユニバーシティ オブ バージニア パテント ファウンデーション | Ａ１アデノシン受容体の２−アミノチアゾールアロステリックエンハンサ |
| CA2530634A1 (en) * | 2003-06-12 | 2004-12-23 | Menachem Rubinstein | Methods of treating obesity and related disorders using tellurium and selenium compounds |
| CA2575339A1 (en) * | 2004-08-05 | 2006-02-09 | F. Hoffmann-La Roche Ag | Substituted n-acyl-2-aminothiazoles |
| WO2006080406A1 (ja) * | 2005-01-28 | 2006-08-03 | Taisho Pharmaceutical Co., Ltd. | 三環性化合物 |
| ES2480994T3 (es) | 2008-03-31 | 2014-07-29 | Genentech, Inc. | Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso |
| ES2558742T3 (es) | 2009-09-28 | 2016-02-08 | F. Hoffmann-La Roche Ag | Compuestos inhibidores de PI3K de benzoxepina y métodos de uso |
| ES2570569T3 (es) | 2009-09-28 | 2016-05-19 | Hoffmann La Roche | Compuestos de benzoxazepina como inhibidores de la PI3K y métodos de uso |
| WO2012126901A1 (en) | 2011-03-21 | 2012-09-27 | F. Hoffmann-La Roche Ag | Benzoxazepin compounds selective for pi3k p110 delta and methods of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3507868A (en) * | 1968-10-21 | 1970-04-21 | Sandoz Ag | Imidazo(2,1-b)thiazoles and thiazolo(3,2-a)pyrimidines |
| DE2640358A1 (de) * | 1976-09-08 | 1978-03-16 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
| JPS5334471A (en) * | 1976-09-10 | 1978-03-31 | Toshiba Corp | Manufacture for semiconductor device |
| CA1292226C (en) * | 1986-01-16 | 1991-11-19 | Terumi Hachiya | Indenothiazole derivative and process for preparing the same |
| IE68593B1 (en) * | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
| DE19831878C2 (de) * | 1998-07-17 | 2001-05-17 | Aventis Pharma Gmbh | Polycyclische Thiazolidin-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE19908538A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen |
-
1999
- 1999-02-26 DE DE19908537A patent/DE19908537A1/de not_active Withdrawn
-
2000
- 2000-02-05 BR BR0008557-0A patent/BR0008557A/pt not_active IP Right Cessation
- 2000-02-05 AT AT00905028T patent/ATE267597T1/de not_active IP Right Cessation
- 2000-02-05 HK HK02107056.4A patent/HK1045809B/zh not_active IP Right Cessation
- 2000-02-05 DK DK00905028T patent/DK1173176T3/da active
- 2000-02-05 WO PCT/EP2000/000925 patent/WO2000051602A1/de not_active Ceased
- 2000-02-05 EP EP00905028A patent/EP1173176B1/de not_active Expired - Lifetime
- 2000-02-05 AU AU26703/00A patent/AU766295B2/en not_active Ceased
- 2000-02-05 JP JP2000602070A patent/JP4728483B2/ja not_active Expired - Fee Related
- 2000-02-05 DE DE50006603T patent/DE50006603D1/de not_active Expired - Lifetime
- 2000-02-05 PT PT00905028T patent/PT1173176E/pt unknown
- 2000-02-05 CA CA002362554A patent/CA2362554A1/en not_active Abandoned
- 2000-02-05 KR KR1020017010840A patent/KR20020002394A/ko not_active Ceased
- 2000-02-05 CN CNB008042209A patent/CN1161120C/zh not_active Expired - Fee Related
- 2000-02-05 ES ES00905028T patent/ES2218122T3/es not_active Expired - Lifetime
- 2000-02-10 US US09/501,209 patent/US6476059B1/en not_active Expired - Lifetime
-
2001
- 2001-07-27 ZA ZA200106199A patent/ZA200106199B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0008557A (pt) | 2001-12-18 |
| CN1161120C (zh) | 2004-08-11 |
| JP2002538117A (ja) | 2002-11-12 |
| AU766295B2 (en) | 2003-10-16 |
| DK1173176T3 (da) | 2004-09-27 |
| JP4728483B2 (ja) | 2011-07-20 |
| DE19908537A1 (de) | 2000-08-31 |
| CA2362554A1 (en) | 2000-09-08 |
| EP1173176A1 (de) | 2002-01-23 |
| EP1173176B1 (de) | 2004-05-26 |
| ES2218122T3 (es) | 2004-11-16 |
| DE50006603D1 (de) | 2004-07-01 |
| ZA200106199B (en) | 2002-03-06 |
| KR20020002394A (ko) | 2002-01-09 |
| ATE267597T1 (de) | 2004-06-15 |
| HK1045809A1 (en) | 2002-12-13 |
| HK1045809B (zh) | 2005-04-22 |
| US6476059B1 (en) | 2002-11-05 |
| WO2000051602A1 (de) | 2000-09-08 |
| CN1349404A (zh) | 2002-05-15 |
| AU2670300A (en) | 2000-09-21 |
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