PT1137792E - Vector recombinado que exprime moléculas costimulantes múltiplas e as suas utilizações - Google Patents
Vector recombinado que exprime moléculas costimulantes múltiplas e as suas utilizações Download PDFInfo
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- PT1137792E PT1137792E PT99958951T PT99958951T PT1137792E PT 1137792 E PT1137792 E PT 1137792E PT 99958951 T PT99958951 T PT 99958951T PT 99958951 T PT99958951 T PT 99958951T PT 1137792 E PT1137792 E PT 1137792E
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- C07K14/70528—CD58
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K2239/58—Prostate
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
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- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US6756038B1 (en) * | 1997-10-10 | 2004-06-29 | The United States Of America As Represented By The Department Of Health And Human Services | Agonist and antagonist peptides of carcinoembryonic antigen (CEA) |
| DE10048710A1 (de) * | 1999-09-27 | 2001-10-04 | Gabriele Pecher | Pharmazeutische Zusammensetzung zur Behandlung und Prophylaxe von humanen Tumoren, die das Tumorantigen Muzin und/oder das Carcinoembryonale Antigen (CEA) exprimieren und ihre Verwendung |
| CA2388337C (en) * | 1999-10-22 | 2013-01-08 | Aventis Pasteur Limited | Method of inducing and/or enhancing an immune response to tumor antigens |
| US7186515B1 (en) | 2000-06-02 | 2007-03-06 | University Of Connecticut Health Center | Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
| US7179462B2 (en) | 2000-06-02 | 2007-02-20 | University Of Connecticut Health Center | α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
| EP1286693A4 (en) | 2000-06-02 | 2005-07-13 | Univ Connecticut Health Ct | COMPLEXES OF ALPHA (2) MACROGLOBULIN AND ANTIGENIC MOLECULES FOR USE IN IMMUNOTHERAPY |
| AU2001278330A1 (en) * | 2000-07-31 | 2002-02-13 | Aventis Pasteur Limited | Modified CEA and uses thereof |
| US7025968B2 (en) | 2000-08-30 | 2006-04-11 | Chemocentryx, Inc. | CMV vaccines |
| EP1320620B1 (en) | 2000-09-25 | 2015-01-21 | The Regents Of The University Of Michigan | Production of viral vectors |
| CA2437201C (en) | 2001-02-02 | 2008-11-18 | Chemocentryx, Inc. | Methods and compositions useful for stimulating an immune response |
| WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| US7414032B2 (en) | 2001-06-25 | 2008-08-19 | Immunofrontier, Inc. | Vaccine comprising a polynucleotide encoding an antigen recognized by a CD4+ helper T-cell and a polynucleotide encoding a tumor specific or associated antigen recognized by a CD8+ CTL |
| AU2003301021C1 (en) | 2002-12-16 | 2010-02-18 | Globelmmune, Inc. | Yeast-based vaccines as immunotherapy |
| WO2005026370A2 (en) * | 2003-09-05 | 2005-03-24 | Sanofi Pasteur Limted. | Multi-antigen vectors for melanoma |
| KR101162970B1 (ko) * | 2003-10-08 | 2012-07-12 | 테리온 바이오로직스, 인크. | 변형된 ｃｅａ/ｂ7 벡터 |
| WO2005046622A2 (en) | 2003-11-12 | 2005-05-26 | Therion Biologics Corporation | Custom vectors for treating and preventing pancreatic cancer |
| US8933041B2 (en) * | 2003-11-12 | 2015-01-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | System for treating and preventing breast cancer |
| WO2005068640A2 (en) * | 2003-12-23 | 2005-07-28 | Aventis Pasteur, Inc. | Modified ksa and uses thereof |
| CN1976946A (zh) * | 2004-07-03 | 2007-06-06 | 财团法人牧岩生命工学研究所 | 诱导抗hcv有效ctl应答的超型表位、其编码寡核苷酸及其应用 |
| US7785875B2 (en) | 2004-07-03 | 2010-08-31 | Mogam Biotechnology Research Institute | Polynucleotide encoding HCV epitopes which can bind to various HLA supertypes, immunogenic composition comprising same and method of inducing an HCV-specific immune response using same |
| ES2313807B1 (es) * | 2005-07-30 | 2009-12-23 | Consejo Superior De Investigaciones Cientificas | Vectores recombinantes basados en el virus vaccinia modificado de ankara (mva) como vacunas contra la leishmaniasis. |
| EP1792996A1 (en) * | 2005-12-01 | 2007-06-06 | Consejo Superior de Investigaciones Cientificas | Nucleic acid sequences encoding vaccines against Porcine reproductive and respiratory syndrome virus (PRRSV) |
| SI2856876T1 (en) | 2007-03-30 | 2018-04-30 | Memorial Sloan-Kettering Cancer Center | Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes |
| WO2009006479A2 (en) | 2007-07-02 | 2009-01-08 | Etubics Corporation | Methods and compositions for producing an adenovirus vector for use with multiple vaccinations |
| NZ584042A (en) * | 2007-10-18 | 2012-09-28 | Bn Immunotherapeutics Inc | Use of mva to treat prostate cancer |
| US8475790B2 (en) | 2008-10-06 | 2013-07-02 | Bristol-Myers Squibb Company | Combination of CD137 antibody and CTLA-4 antibody for the treatment of proliferative diseases |
| US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
| ES2547654T3 (es) * | 2008-10-31 | 2015-10-07 | Tremrx, Inc. | Vacunación con vectores poxvirales mediante alteración mecánica epidérmica |
| CA2759013C (en) | 2009-04-17 | 2021-10-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combination immunotherapy compositions against cancer and methods |
| RU2642300C2 (ru) | 2011-08-17 | 2018-01-24 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения |
| US9605276B2 (en) | 2012-08-24 | 2017-03-28 | Etubics Corporation | Replication defective adenovirus vector in vaccination |
| CN105431157A (zh) | 2013-06-14 | 2016-03-23 | 普赛奥克苏斯治疗公司 | 用于b型腺病毒的给药方案及制剂 |
| TR201802728T4 (tr) | 2013-10-25 | 2018-03-21 | Psioxus Therapeutics Ltd | Heterolog genlerle donatılmış onkolitik adenovirüsler. |
| MX377258B (es) * | 2013-11-28 | 2025-03-07 | Bavarian Nordic As | Composiciones de vectores poxvirus y su uso para inducir una respuesta inmunitaria. |
| JP5917626B2 (ja) * | 2014-07-28 | 2016-05-18 | トレムアールエックス， インコーポレイテッド | 機械的表皮破壊を介したポックスウイルスベクターによるワクチン接種 |
| AU2016205208A1 (en) | 2015-01-09 | 2017-07-06 | Etubics Corporation | Methods and compositions for ebola virus vaccination |
| JP6647315B2 (ja) * | 2015-01-09 | 2020-02-14 | イーチュービクス コーポレイション | 組み合わせ免疫療法のための方法および組成物 |
| US11149087B2 (en) | 2015-04-20 | 2021-10-19 | Etubics Corporation | Methods and compositions for combination immunotherapy |
| PE20180241A1 (es) * | 2015-04-30 | 2018-01-31 | Psioxus Therapeutics Ltd | Adenovirus oncolitico que codifica una proteina b7 |
| KR102857666B1 (ko) | 2015-12-17 | 2025-09-10 | 아카미스 바이오 리미티드 | 항-tcr-복합체 항체 또는 단편을 암호화하는 군 b 아데노바이러스 |
| SG11201808058PA (en) * | 2016-03-18 | 2018-10-30 | Nantcell Inc | Multimodal vector for dendritic cell infection |
| KR20200138418A (ko) * | 2016-05-27 | 2020-12-09 | 이투빅스 코포레이션 | 네오에피토프 백신 조성물 및 이의 사용 방법 |
| AU2017320776B2 (en) | 2016-08-29 | 2024-10-10 | Akamis Bio Limited | Adenovirus armed with bispecific T cell activator |
| GB201713765D0 (en) | 2017-08-28 | 2017-10-11 | Psioxus Therapeutics Ltd | Modified adenovirus |
| US11844824B2 (en) * | 2018-03-06 | 2023-12-19 | Pepvax, Inc. | Nucleic acid molecules and methods of using the same |
| WO2020061203A1 (en) | 2018-09-21 | 2020-03-26 | Nantcell, Inc. | Methods and compositions for modulating myeloid-derived suppressor cells |
| GB202010095D0 (en) * | 2020-07-01 | 2020-08-12 | Tcer Ab | Immunotherapy |
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| DE69435010T2 (de) * | 1993-04-20 | 2008-04-30 | Hipler Partners Llp | Verfahren und stoffe für die behandlung von individuen, die infiziert sind mit intrazellulär infektiösen agentien |
| EP1016418B1 (en) * | 1994-10-03 | 2009-12-30 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Host cell comprising a recombinant virus expressing an antigen and a recombinant virus expressing an immunostimulatory molecule |
| AU731860B2 (en) * | 1996-07-25 | 2001-04-05 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Recombinant pox virus for immunization against tumor-associated antigens |
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- 1999-11-12 JP JP2000586927A patent/JP4409097B2/ja not_active Expired - Lifetime
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| EP1137792A1 (en) | 2001-10-04 |
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| CY1107698T1 (el) | 2013-04-18 |
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| CA2354024A1 (en) | 2000-06-15 |
| EP1137792B1 (en) | 2007-05-09 |
| AU774076B2 (en) | 2004-06-17 |
| DE69936061D1 (de) | 2007-06-21 |
| DE69936061T2 (de) | 2008-01-17 |
| ES2286902T3 (es) | 2007-12-01 |
| ATE361988T1 (de) | 2007-06-15 |
| JP2009254390A (ja) | 2009-11-05 |
| JP5254153B2 (ja) | 2013-08-07 |
| EP1137792B9 (en) | 2007-12-12 |
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