PL4106757T3 - Sposoby z udziałem inhibitora elastazy neutrofilowej, alwelestatu, do leczenia choroby układu oddechowego, w której pośredniczy niedobór alfa-1 antytrypsyny - Google Patents

Sposoby z udziałem inhibitora elastazy neutrofilowej, alwelestatu, do leczenia choroby układu oddechowego, w której pośredniczy niedobór alfa-1 antytrypsyny

Info

Publication number
PL4106757T3
PL4106757T3 PL21714345.2T PL21714345T PL4106757T3 PL 4106757 T3 PL4106757 T3 PL 4106757T3 PL 21714345 T PL21714345 T PL 21714345T PL 4106757 T3 PL4106757 T3 PL 4106757T3
Authority
PL
Poland
Prior art keywords
alvelestat
alpha
respiratory disease
methods involving
neutrophil elastase
Prior art date
Application number
PL21714345.2T
Other languages
English (en)
Polish (pl)
Inventor
Jacqueline PARKIN
Original Assignee
Mereo Biopharma 4 Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2005519.0A external-priority patent/GB202005519D0/en
Priority claimed from GBGB2005520.8A external-priority patent/GB202005520D0/en
Application filed by Mereo Biopharma 4 Limited filed Critical Mereo Biopharma 4 Limited
Publication of PL4106757T3 publication Critical patent/PL4106757T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PL21714345.2T 2020-04-16 2021-03-16 Sposoby z udziałem inhibitora elastazy neutrofilowej, alwelestatu, do leczenia choroby układu oddechowego, w której pośredniczy niedobór alfa-1 antytrypsyny PL4106757T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB2005519.0A GB202005519D0 (en) 2020-04-16 2020-04-16 Elastase inhibition
GBGB2005520.8A GB202005520D0 (en) 2020-04-16 2020-04-16 Elastase inhibition
US202062706195P 2020-08-04 2020-08-04
PCT/GB2021/050653 WO2021209739A1 (en) 2020-04-16 2021-03-16 Methods involving neutrophil elastase inhibitor alvelestat for treating respiratory disease mediated by alpha-1 antitrypsin deficiency

Publications (1)

Publication Number Publication Date
PL4106757T3 true PL4106757T3 (pl) 2024-01-22

Family

ID=78083570

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21714345.2T PL4106757T3 (pl) 2020-04-16 2021-03-16 Sposoby z udziałem inhibitora elastazy neutrofilowej, alwelestatu, do leczenia choroby układu oddechowego, w której pośredniczy niedobór alfa-1 antytrypsyny

Country Status (16)

Country Link
US (2) US20230218596A1 (de)
EP (2) EP4252850A3 (de)
JP (1) JP2023522010A (de)
AU (1) AU2021256835A1 (de)
DK (1) DK4106757T3 (de)
ES (1) ES2962498T3 (de)
FI (1) FI4106757T3 (de)
HR (1) HRP20231065T1 (de)
HU (1) HUE064089T2 (de)
IL (1) IL297211A (de)
LT (1) LT4106757T (de)
MX (1) MX2022012942A (de)
PL (1) PL4106757T3 (de)
PT (1) PT4106757T (de)
SI (1) SI4106757T1 (de)
WO (2) WO2021209739A1 (de)

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Also Published As

Publication number Publication date
US20230190723A1 (en) 2023-06-22
EP4106757B1 (de) 2023-08-23
HRP20231065T1 (hr) 2023-12-22
LT4106757T (lt) 2023-11-10
JP2023522010A (ja) 2023-05-26
SI4106757T1 (sl) 2023-11-30
US20230218596A1 (en) 2023-07-13
WO2021209739A1 (en) 2021-10-21
ES2962498T3 (es) 2024-03-19
DK4106757T3 (da) 2023-10-23
EP4106757A1 (de) 2022-12-28
IL297211A (en) 2022-12-01
PT4106757T (pt) 2023-11-17
EP4252850A3 (de) 2023-11-15
FI4106757T3 (fi) 2023-10-23
EP4252850A2 (de) 2023-10-04
HUE064089T2 (hu) 2024-02-28
MX2022012942A (es) 2023-01-11
WO2021209740A1 (en) 2021-10-21
AU2021256835A1 (en) 2022-10-13

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