PL374846A1 - Nowe związki do hamowania rotamaz i ich zastosowanie - Google Patents

Nowe związki do hamowania rotamaz i ich zastosowanie

Info

Publication number
PL374846A1
PL374846A1 PL03374846A PL37484603A PL374846A1 PL 374846 A1 PL374846 A1 PL 374846A1 PL 03374846 A PL03374846 A PL 03374846A PL 37484603 A PL37484603 A PL 37484603A PL 374846 A1 PL374846 A1 PL 374846A1
Authority
PL
Poland
Prior art keywords
rotamases
inhibition
new compounds
compounds
new
Prior art date
Application number
PL03374846A
Other languages
English (en)
Inventor
Jochen Knolle
Mike Schutkowski
Gerd Hummel
Thomas Tradler
Laurence Jobron
Claudia Christner
Dirk Scharn
Roland Stragies
Christoph Gibson
Frank Osterkamp
Original Assignee
Jerini Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jerini Ag filed Critical Jerini Ag
Publication of PL374846A1 publication Critical patent/PL374846A1/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • C07—ORGANIC CHEMISTRY
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    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Virology (AREA)
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  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
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PL03374846A 2002-09-18 2003-09-18 Nowe związki do hamowania rotamaz i ich zastosowanie PL374846A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20020020987 EP1402888A1 (en) 2002-09-18 2002-09-18 The use of substituted carbocyclic compounds as rotamases inhibitors

Publications (1)

Publication Number Publication Date
PL374846A1 true PL374846A1 (pl) 2005-11-14

Family

ID=31970282

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03374846A PL374846A1 (pl) 2002-09-18 2003-09-18 Nowe związki do hamowania rotamaz i ich zastosowanie

Country Status (14)

Country Link
US (2) US20070054904A1 (pl)
EP (3) EP1402888A1 (pl)
JP (2) JP2005539072A (pl)
KR (1) KR20050053673A (pl)
CN (1) CN100546977C (pl)
AU (1) AU2003271619A1 (pl)
BR (1) BR0314544A (pl)
CA (1) CA2498662A1 (pl)
MX (1) MXPA05003084A (pl)
PL (1) PL374846A1 (pl)
RU (2) RU2005111256A (pl)
SG (1) SG165995A1 (pl)
WO (1) WO2004026815A2 (pl)
ZA (1) ZA200501913B (pl)

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WO2004071447A2 (en) * 2003-02-12 2004-08-26 Transtech Pharma Inc. Substituted azole derivatives as therapeutic agents
EP1608319A4 (en) * 2003-04-03 2007-02-28 Univ California IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE
WO2005061455A1 (en) * 2003-12-23 2005-07-07 H. Lundbeck A/S 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
EP1713780B1 (en) * 2004-02-05 2012-01-18 Probiodrug AG Novel inhibitors of glutaminyl cyclase
JP2007532484A (ja) 2004-03-16 2007-11-15 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 可溶性エポキシド加水分解酵素の阻害剤およびエポキシエイコサノイドを用いて腎症を緩和する方法
US7550499B2 (en) 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
CN1984899B (zh) * 2004-05-12 2011-07-27 先灵公司 Cxcr1和cxcr2趋化因子拮抗剂
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
ZA200703613B (en) * 2004-10-20 2009-05-27 Univ California Improved inhibitors for the soluble epoxide hydrolase
AU2006206611A1 (en) 2005-01-19 2006-07-27 Bristol-Myers Squibb Company 2-phenoxy-N- (1, 3 , 4-thiadizol-2-yl) pyridin-3-amine derivatives and related compounds as P2Y1 receptor inhibitors for the treatment of thromboembolic disorders
US7417072B2 (en) * 2005-05-12 2008-08-26 Wisconsin Alumni Research Foundation Blockade of Pin1 prevents cytokine production by activated immune cells
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