PL373912A1 - Heterocykliczne pochodne do leczenia raka i innych chorób proliferacyjnych - Google Patents
Heterocykliczne pochodne do leczenia raka i innych chorób proliferacyjnychInfo
- Publication number
- PL373912A1 PL373912A1 PL02373912A PL37391202A PL373912A1 PL 373912 A1 PL373912 A1 PL 373912A1 PL 02373912 A PL02373912 A PL 02373912A PL 37391202 A PL37391202 A PL 37391202A PL 373912 A1 PL373912 A1 PL 373912A1
- Authority
- PL
- Poland
- Prior art keywords
- cancer
- treatment
- proliferative diseases
- heterocyclic derivatives
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27475101P | 2001-03-07 | 2001-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL373912A1 true PL373912A1 (pl) | 2005-09-19 |
Family
ID=23049469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02373912A PL373912A1 (pl) | 2001-03-07 | 2002-03-07 | Heterocykliczne pochodne do leczenia raka i innych chorób proliferacyjnych |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7153875B2 (pl) |
| EP (1) | EP1385465A4 (pl) |
| JP (1) | JP2005506290A (pl) |
| AU (1) | AU2002252227A1 (pl) |
| BR (1) | BR0207846A (pl) |
| CA (1) | CA2440184A1 (pl) |
| EA (1) | EA200300982A1 (pl) |
| IL (1) | IL157740A0 (pl) |
| MX (1) | MXPA03008117A (pl) |
| NO (1) | NO20033883L (pl) |
| PL (1) | PL373912A1 (pl) |
| WO (1) | WO2002072009A2 (pl) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2383347A1 (en) | 1999-08-31 | 2001-03-08 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| IL157740A0 (en) | 2001-03-07 | 2004-03-28 | Incyte San Diego Inc | Heterocyclic derivatives and pharmaceutical compositions containing the same |
| US7265139B2 (en) | 2001-03-08 | 2007-09-04 | Incyte San Diego Inc. | RXR activating molecules |
| EP1421061A4 (en) * | 2001-08-17 | 2004-12-22 | Incyte San Diego Inc | OXIME DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA AND HYPERCHOLESTEROLEMIA |
| AU2002352706A1 (en) * | 2001-11-15 | 2003-06-10 | Maxia Pharmaceuticals, Inc. | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
| AU2002346620A1 (en) | 2001-11-30 | 2003-06-17 | Department Of Veteran Affairs | Induction of apoptosis in cancer cells |
| US7196108B2 (en) * | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| US8008281B2 (en) * | 2003-03-27 | 2011-08-30 | Lankenau Institute For Medical Research | Methods for the treatment of cancer |
| FR2856401B1 (fr) * | 2003-06-20 | 2010-02-12 | Galderma Res & Dev | Nouveaux composes modulateurs des recepteurs de type ppargamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| DE10351744A1 (de) * | 2003-10-31 | 2005-06-16 | Schering Ag | Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel |
| US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
| FR2884248B1 (fr) * | 2005-04-08 | 2007-05-18 | Galderma Res & Dev | Nouveau procede de preparation de l'acide 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoique |
| AU2006233810B2 (en) | 2005-04-08 | 2011-02-17 | Galderma Research & Development | New method for the preparation of 6-(3-(1-adamantyl)-4-methoxphenyl)-2-naphthoic acid |
| KR100814109B1 (ko) * | 2006-01-09 | 2008-03-14 | 한국생명공학연구원 | 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물 |
| PE20080038A1 (es) * | 2006-04-11 | 2008-02-22 | Smithkline Beecham Corp | Derivados de tiazolidinadiona como inhibidores de la pi3 quinasa |
| US20080255115A1 (en) * | 2007-04-11 | 2008-10-16 | Michael Gerard Darcy | Thiazolidinedione derivatives as pi3 kinase inhibitors |
| JP2010526823A (ja) * | 2007-05-10 | 2010-08-05 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | Ｐｉ３キナーゼ阻害物質としてのキノキサリン誘導体 |
| PE20090717A1 (es) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| EP2674417A3 (en) | 2007-11-21 | 2014-04-09 | Decode Genetics EHF | Biaryl PDE4 inhibitors for treating inflammation |
| JP2011505341A (ja) * | 2007-11-21 | 2011-02-24 | デコード ジェネティクス イーエイチエフ | 炎症性、心血管およびｃｎｓ障害を治療するビアリールｐｄｅ４抑制剤 |
| CN102558088A (zh) * | 2010-12-31 | 2012-07-11 | 中国科学院上海药物研究所 | 联苯亚甲基-2-硫代-4-噻唑酮类化合物及其制备方法和用途 |
| WO2023121184A1 (ko) * | 2021-12-21 | 2023-06-29 | (주)메디픽 | 치환된 티아졸리딘디온 유도체 화합물 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4051842A (en) | 1975-09-15 | 1977-10-04 | International Medical Corporation | Electrode and interfacing pad for electrical physiological systems |
| DE2626348C3 (de) | 1976-06-11 | 1980-01-31 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Implantierbare Dosiereinrichtung |
| JPS5538359A (en) | 1978-09-12 | 1980-03-17 | Hamari Yakuhin Kogyo Kk | Preparation of 2-(3-benzoylphenyl)-propionic acid |
| US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| IL72684A (en) | 1984-08-14 | 1989-02-28 | Israel State | Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs |
| US4713244A (en) | 1985-08-16 | 1987-12-15 | Bausch & Lomb Incorporated | Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent |
| US4668506A (en) | 1985-08-16 | 1987-05-26 | Bausch & Lomb Incorporated | Sustained-release formulation containing and amino acid polymer |
| US4931279A (en) | 1985-08-16 | 1990-06-05 | Bausch & Lomb Incorporated | Sustained release formulation containing an ion-exchange resin |
| CA1325222C (en) | 1985-08-23 | 1993-12-14 | Lederle (Japan), Ltd. | Process for producing 4-biphenylylacetic acid |
| WO1988007035A1 (en) | 1987-03-11 | 1988-09-22 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Hydroxystyrene derivatives |
| FI91869C (fi) * | 1987-03-18 | 1994-08-25 | Tanabe Seiyaku Co | Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi |
| US5330998A (en) | 1988-03-08 | 1994-07-19 | Pfizer Inc. | Thiazolidinedione derivatives as hypoglycemic agents |
| US5223522A (en) | 1988-03-08 | 1993-06-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
| IE940525L (en) | 1988-05-25 | 1989-11-25 | Warner Lambert Co | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents |
| DE69227689T2 (de) | 1991-07-22 | 1999-04-22 | Pfizer | Verfahren zur herstellung von (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl] brombenzol |
| ATE195716T1 (de) | 1992-04-22 | 2000-09-15 | Ligand Pharm Inc | Retinoid-x rezeptor selektive verbindungen |
| US5780676A (en) | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
| EP0587377A3 (en) | 1992-09-10 | 1994-09-21 | Lilly Co Eli | Thiazolidinone derivatives as hypoglycemic agents and for treating alzheimer's disease |
| AU700706B2 (en) | 1992-11-25 | 1999-01-14 | Ligand Pharmaceuticals, Inc. | RXR homodimer formation and bridged bicyclic aromatic compounds and their use in modulating gene expression |
| ATE178046T1 (de) | 1994-02-17 | 1999-04-15 | American Home Prod | Substituierte biphenyl-derivate mit phosphodiesterase inhibierender wirkung |
| US5691376A (en) | 1994-02-17 | 1997-11-25 | American Home Products Corporation | Substituted biphenyl derivatives |
| JPH09136877A (ja) | 1995-06-16 | 1997-05-27 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及び用途 |
| JP2000506489A (ja) | 1995-07-17 | 2000-05-30 | センタ インタナショナル ドゥ リシェルシェ デルマトロジーク セ イ エール デ ガルデルマ | Ａｈｐｎを用いる癌の治療方法 |
| EP0844997A1 (en) | 1996-06-19 | 1998-06-03 | Dr. Reddy's Research Foundation | Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation |
| ATE284213T1 (de) | 1996-07-08 | 2004-12-15 | Galderma Res & Dev | Apoptose induzierende adamantyl-derivate und deren verwendung als antikrebsmittel |
| CA2300813A1 (en) | 1997-08-21 | 1999-03-04 | Hiroyuki Odaka | Anti-inflammatory agent |
| US5972986A (en) * | 1997-10-14 | 1999-10-26 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia |
| AU1052599A (en) | 1997-11-12 | 1999-05-31 | Institute Of Medicinal Molecular Design. Inc. | Retinoid receptor agonists |
| US6262044B1 (en) | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
| US6331633B1 (en) | 1998-05-08 | 2001-12-18 | Calyx Therapeutics Inc. | Heterocyclic analogs of diphenylethylene compounds |
| IL141456A0 (en) | 1998-08-21 | 2002-03-10 | Viropharma Inc | Rhodanine derivatives and pharmaceutical compositions containing the same |
| AU6330999A (en) | 1998-09-30 | 2000-04-17 | Roche Diagnostics Gmbh | Rhodanine derivatives for the treatment and prevention of metabolic bone disorders |
| WO2000032598A1 (en) | 1998-12-04 | 2000-06-08 | Structural Bioinformatics Inc. | Methods and compositions for treating inflammatory diseases utilizing inhibitors of tumor necrosis factor activity |
| WO2000063196A1 (en) | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
| CA2383347A1 (en) | 1999-08-31 | 2001-03-08 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| ES2276547T3 (es) | 1999-11-12 | 2007-06-16 | Fujimoto Brothers Co., Ltd. | Derivados de 2-(n-cianoimino)tiazolidin-4-ona. |
| FR2812876B1 (fr) * | 2000-08-08 | 2002-09-27 | Galderma Res & Dev | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| IL157740A0 (en) | 2001-03-07 | 2004-03-28 | Incyte San Diego Inc | Heterocyclic derivatives and pharmaceutical compositions containing the same |
| US7265139B2 (en) | 2001-03-08 | 2007-09-04 | Incyte San Diego Inc. | RXR activating molecules |
| WO2002071827A2 (en) | 2001-03-14 | 2002-09-19 | Eli Lilly And Company | Retinoid x receptor modulators |
| CN100384430C (zh) | 2001-04-04 | 2008-04-30 | 奥索-麦克尼尔药品公司 | 含有葡萄糖重吸收抑制剂和维生素a类-x受体调节剂的联合治疗 |
| EP1421061A4 (en) | 2001-08-17 | 2004-12-22 | Incyte San Diego Inc | OXIME DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA AND HYPERCHOLESTEROLEMIA |
| AU2002352706A1 (en) | 2001-11-15 | 2003-06-10 | Maxia Pharmaceuticals, Inc. | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
| AR037714A1 (es) | 2001-12-06 | 2004-12-01 | Maxia Pharmaceuticals Inc | Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer |
| US7102000B2 (en) | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| EP1638964B1 (en) * | 2003-06-20 | 2011-07-27 | Galderma Research & Development | Novel compounds that modulate ppar-gamma type receptors, and use thereof in cosmetic or pharmaceutical compositions |
-
2002
- 2002-03-07 IL IL15774002A patent/IL157740A0/xx unknown
- 2002-03-07 AU AU2002252227A patent/AU2002252227A1/en not_active Abandoned
- 2002-03-07 PL PL02373912A patent/PL373912A1/pl not_active Application Discontinuation
- 2002-03-07 BR BR0207846-5A patent/BR0207846A/pt not_active Application Discontinuation
- 2002-03-07 EA EA200300982A patent/EA200300982A1/ru unknown
- 2002-03-07 JP JP2002570969A patent/JP2005506290A/ja active Pending
- 2002-03-07 WO PCT/US2002/007001 patent/WO2002072009A2/en not_active Application Discontinuation
- 2002-03-07 MX MXPA03008117A patent/MXPA03008117A/es unknown
- 2002-03-07 CA CA002440184A patent/CA2440184A1/en not_active Abandoned
- 2002-03-07 US US10/094,142 patent/US7153875B2/en not_active Expired - Fee Related
- 2002-03-07 EP EP02721289A patent/EP1385465A4/en not_active Withdrawn
-
2003
- 2003-09-02 NO NO20033883A patent/NO20033883L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1385465A4 (en) | 2005-09-07 |
| WO2002072009A2 (en) | 2002-09-19 |
| JP2005506290A (ja) | 2005-03-03 |
| WO2002072009A3 (en) | 2003-10-16 |
| EP1385465A2 (en) | 2004-02-04 |
| IL157740A0 (en) | 2004-03-28 |
| NO20033883L (no) | 2003-11-05 |
| MXPA03008117A (es) | 2004-11-12 |
| US7153875B2 (en) | 2006-12-26 |
| AU2002252227A1 (en) | 2002-09-24 |
| NO20033883D0 (no) | 2003-09-02 |
| US20020143182A1 (en) | 2002-10-03 |
| CA2440184A1 (en) | 2002-09-19 |
| BR0207846A (pt) | 2005-09-13 |
| EA200300982A1 (ru) | 2004-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |