PL371264A1 - Sposób leczenia chorób kości - Google Patents
Sposób leczenia chorób kościInfo
- Publication number
- PL371264A1 PL371264A1 PL02371264A PL37126402A PL371264A1 PL 371264 A1 PL371264 A1 PL 371264A1 PL 02371264 A PL02371264 A PL 02371264A PL 37126402 A PL37126402 A PL 37126402A PL 371264 A1 PL371264 A1 PL 371264A1
- Authority
- PL
- Poland
- Prior art keywords
- treatment
- bone disorders
- risedronate
- polymorph
- solvate
- Prior art date
Links
- 208000020084 Bone disease Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- IIDJRNMFWXDHID-UHFFFAOYSA-N Risedronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CC1=CC=CN=C1 IIDJRNMFWXDHID-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000001186 cumulative effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940089617 risedronate Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34487501P | 2001-12-21 | 2001-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL371264A1 true PL371264A1 (pl) | 2005-06-13 |
Family
ID=23352430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL02371264A PL371264A1 (pl) | 2001-12-21 | 2002-12-16 | Sposób leczenia chorób kości |
Country Status (24)
Country | Link |
---|---|
US (5) | US20030118634A1 (pl) |
EP (1) | EP1455796A1 (pl) |
JP (1) | JP2005514400A (pl) |
KR (1) | KR100638122B1 (pl) |
CN (1) | CN100479823C (pl) |
AR (1) | AR038041A1 (pl) |
AU (1) | AU2002360619B2 (pl) |
CA (1) | CA2469779C (pl) |
CZ (1) | CZ2004690A3 (pl) |
HK (1) | HK1087039A1 (pl) |
HU (1) | HUP0402267A3 (pl) |
IL (2) | IL162053A0 (pl) |
MA (1) | MA27157A1 (pl) |
MX (1) | MXPA04006027A (pl) |
MY (1) | MY147886A (pl) |
NO (1) | NO340249B1 (pl) |
NZ (1) | NZ532994A (pl) |
PE (1) | PE20030743A1 (pl) |
PL (1) | PL371264A1 (pl) |
RU (1) | RU2294203C2 (pl) |
SK (1) | SK2532004A3 (pl) |
TW (1) | TWI349553B (pl) |
WO (1) | WO2003055496A1 (pl) |
ZA (1) | ZA200404007B (pl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003055496A1 (en) * | 2001-12-21 | 2003-07-10 | The Procter & Gamble Company | Method for the treatment of bone disorders |
KR20120065435A (ko) * | 2002-05-10 | 2012-06-20 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
US20040097468A1 (en) * | 2002-11-20 | 2004-05-20 | Wimalawansa Sunil J. | Method of treating osteoporosis and other bone disorders with upfront loading of bisphosphonates, and kits for such treatment |
BR0309691A (pt) * | 2002-12-20 | 2005-08-02 | Hoffmann La Roche | Formulação de ibandronato em alta dose |
KR20080083068A (ko) * | 2004-05-24 | 2008-09-12 | 더 프록터 앤드 갬블 캄파니 | 킬레이팅제를 함유하는 비스포스포네이트의 고형의 장용 경구 투여 형태 |
WO2006020009A1 (en) * | 2004-07-23 | 2006-02-23 | The Procter & Gamble Company | Solid oral dosage form of a bisphosphonate containing a chelating agent |
US20070191315A1 (en) * | 2006-02-16 | 2007-08-16 | Bengt Bergstrom | Method for administering ibandronate |
Family Cites Families (68)
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CA777769A (en) * | 1963-03-18 | 1968-02-06 | H. Roy Clarence | Substituted methylene diphosphonic acid compounds and detergent compositions |
DE2405254C2 (de) * | 1974-02-04 | 1982-05-27 | Henkel KGaA, 4000 Düsseldorf | Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper |
DE2534391C2 (de) * | 1975-08-01 | 1983-01-13 | Henkel KGaA, 4000 Düsseldorf | 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren |
DE2745083C2 (de) * | 1977-10-07 | 1985-05-02 | Henkel KGaA, 4000 Düsseldorf | Hydroxydiphosphonsäuren und Verfahren zu deren Herstellung |
US4252742A (en) * | 1979-07-13 | 1981-02-24 | Ciba-Geigy Corporation | Chemical process for the preparation of 2,6-dialkylcyclohexylamines from 2,6-dialkylphenols |
DE2943498C2 (de) * | 1979-10-27 | 1983-01-27 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur Herstellung von 3-Amino-1-hydroxypropan-1,1-diphosphonsäure |
DE3016289A1 (de) * | 1980-04-28 | 1981-10-29 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren |
IT1201087B (it) * | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
FR2531088B1 (fr) * | 1982-07-29 | 1987-08-28 | Sanofi Sa | Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation |
DE3434667A1 (de) * | 1984-09-21 | 1986-04-03 | Henkel KGaA, 4000 Düsseldorf | 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung |
IT1196315B (it) * | 1984-10-29 | 1988-11-16 | Gentili Ist Spa | Procedimento per la preparazione di acidi difosfonici |
IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
US4812311A (en) * | 1984-12-21 | 1989-03-14 | The Procter & Gamble Company | Kit for use in the treatment of osteoporosis |
DE3512536A1 (de) * | 1985-04-06 | 1986-10-16 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue diphosphonsaeure-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
US4761406A (en) * | 1985-06-06 | 1988-08-02 | The Procter & Gamble Company | Regimen for treating osteoporosis |
DE3540150A1 (de) * | 1985-11-13 | 1987-05-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3623397A1 (de) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3626058A1 (de) * | 1986-08-01 | 1988-02-11 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3640938A1 (de) * | 1986-11-29 | 1988-06-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindung enthaltende arzneimittel |
CA1339805C (en) * | 1988-01-20 | 1998-04-07 | Yasuo Isomura | (cycloalkylamino)methylenebis(phosphonic acid) and medicines containing the same as an active |
EP0333082A3 (en) * | 1988-03-15 | 1991-05-02 | Takeda Chemical Industries, Ltd. | Cephem compounds, their production and use |
GB2217988B (en) * | 1988-04-11 | 1992-04-01 | Gould Leonard W | Regimen for increasing bone density in humans |
DE3822650A1 (de) * | 1988-07-05 | 1990-02-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
US5018651A (en) * | 1988-12-27 | 1991-05-28 | Hull Harold L | Side or end dump article carrier |
DE3917153A1 (de) * | 1989-05-26 | 1990-11-29 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
US4922007A (en) * | 1989-06-09 | 1990-05-01 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof |
NL8902727A (nl) * | 1989-11-06 | 1991-06-03 | Philips Nv | Objecthouder voor ondersteuning van een object in een geladen deeltjesbundelsysteem. |
US5356887A (en) * | 1990-01-31 | 1994-10-18 | Merck & Co., Inc. | Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids |
US5019651A (en) * | 1990-06-20 | 1991-05-28 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof |
TW237386B (pl) * | 1992-04-15 | 1995-01-01 | Ciba Geigy | |
CZ297094A3 (en) * | 1992-05-29 | 1995-12-13 | Procter & Gamble Pharma | Phosphate compounds containing quaternary nitrogen, their use and pharmaceutical compositions containing thereof |
US5391743A (en) * | 1992-05-29 | 1995-02-21 | Procter & Gamble Pharmaceuticals, Inc. | Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental calculus and plaque |
CA2138366C (en) * | 1992-06-30 | 1998-09-22 | Kristine Hovancik | Methods for the treatment of arthritis using phosphonates and nsaids |
US5358941A (en) * | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
FR2703590B1 (fr) * | 1993-04-05 | 1995-06-30 | Sanofi Elf | Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse . |
US5431920A (en) * | 1993-09-21 | 1995-07-11 | Merck Frosst, Canada, Inc. | Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents |
US5646134A (en) * | 1994-04-21 | 1997-07-08 | Merck & Co., Inc. | Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices |
US20010007863A1 (en) * | 1998-06-18 | 2001-07-12 | Merck & Co., Inc. | Wet granulation formulation for bisphosphonic acids |
US5462932A (en) * | 1994-05-17 | 1995-10-31 | Merck & Co., Inc. | Oral liquid alendronate formulations |
US6008206A (en) * | 1994-09-21 | 1999-12-28 | Merck & Co., Inc. | Sodium alendronate preparation for local administration |
US20010051616A1 (en) * | 1995-02-17 | 2001-12-13 | David B. Karpf | Method of lessening the risk of vertebral fractures |
EP0832195B1 (de) * | 1995-06-07 | 2005-11-09 | co.don Aktiengesellschaft | Verfahren zur osteoporosediagnose und zur testung potentieller osteoporose-therapeutika unter verwendung von standardisierten, primären osteoblastenzellkulturen aus osteoporotischen patienten |
DE19615812A1 (de) * | 1996-04-20 | 1997-10-23 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation |
GB2324726A (en) * | 1997-05-01 | 1998-11-04 | Merck & Co Inc | Combination Therapy for the Treatment of Osteoporosis |
US5994329A (en) * | 1997-07-22 | 1999-11-30 | Merck & Co., Inc. | Method for inhibiting bone resorption |
US6432932B1 (en) * | 1997-07-22 | 2002-08-13 | Merck & Co., Inc. | Method for inhibiting bone resorption |
US6124314A (en) * | 1997-10-10 | 2000-09-26 | Pfizer Inc. | Osteoporosis compounds |
US6432931B1 (en) * | 1998-06-24 | 2002-08-13 | Merck & Co., Inc. | Compositions and methods for inhibiting bone resorption |
IT1303672B1 (it) * | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali nitrati di farmaci attivi nei disordini ossei |
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US6468559B1 (en) * | 2000-04-28 | 2002-10-22 | Lipocine, Inc. | Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods |
CN1224423C (zh) * | 2000-07-17 | 2005-10-26 | 山之内制药株式会社 | 改善口服吸收的医药组合物 |
WO2002007733A2 (en) * | 2000-07-19 | 2002-01-31 | Eli Lilly And Company | Method for enhancing bone mineral density gain by administration of raloxifene |
US6638920B2 (en) * | 2000-07-21 | 2003-10-28 | Merck & Co., Inc. | Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses |
ES2243457T3 (es) * | 2001-01-23 | 2005-12-01 | Gador S.A. | Composicion que comprende bifosfonatos para la prevencion y/o tratamiento de trastornos metabolicos de huesos, procedimiento de preparacion de dicha composicion y usos de la misma. |
AR034199A1 (es) * | 2001-02-01 | 2004-02-04 | Riderway Corp | Composicion farmacologica liquida para el tratamiento de enfermedades oseas y procedimientos para su elaboracion |
CN1233325C (zh) * | 2001-02-06 | 2005-12-28 | 罗亚尔·亚历山德拉儿童医院 | 治疗骨坏死和处理有发展为骨坏死危险的患者用的药物 |
MXPA03007837A (es) * | 2001-03-01 | 2004-03-16 | Emisphere Techonologies Inc | Composiciones para suministrar bisfosfonatos. |
AU2002305359B2 (en) * | 2001-05-10 | 2005-05-26 | Merck & Co., Inc. | Estrogen receptor modulators |
US20030139378A1 (en) * | 2001-12-13 | 2003-07-24 | Daifotis Anastasia G. | Liquid bisphosphonate formulations for bone disorders |
WO2003055496A1 (en) * | 2001-12-21 | 2003-07-10 | The Procter & Gamble Company | Method for the treatment of bone disorders |
US20050070504A1 (en) * | 2001-12-21 | 2005-03-31 | The Procter & Gamble Co. | Risedronate compositions and their methods of use |
US7488496B2 (en) * | 2002-03-06 | 2009-02-10 | Christer Rosen | Effervescent compositions comprising bisphosphonates and methods related thereto |
WO2003086415A1 (en) * | 2002-04-05 | 2003-10-23 | Merck & Co., Inc. | Method for inhibiting bone resorption with an alendronate and vitamin d formulation |
KR20120065435A (ko) * | 2002-05-10 | 2012-06-20 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
US20040188316A1 (en) * | 2003-03-26 | 2004-09-30 | The Procter & Gamble Company | Kit for pharmaceutical use |
-
2002
- 2002-12-16 WO PCT/US2002/040234 patent/WO2003055496A1/en active Application Filing
- 2002-12-16 PL PL02371264A patent/PL371264A1/pl not_active Application Discontinuation
- 2002-12-16 SK SK253-2004A patent/SK2532004A3/sk unknown
- 2002-12-16 AU AU2002360619A patent/AU2002360619B2/en not_active Expired
- 2002-12-16 CA CA002469779A patent/CA2469779C/en not_active Expired - Lifetime
- 2002-12-16 CZ CZ2004690A patent/CZ2004690A3/cs unknown
- 2002-12-16 RU RU2004122433/14A patent/RU2294203C2/ru active
- 2002-12-16 NZ NZ532994A patent/NZ532994A/en not_active IP Right Cessation
- 2002-12-16 JP JP2003556073A patent/JP2005514400A/ja active Pending
- 2002-12-16 EP EP20020795891 patent/EP1455796A1/en not_active Ceased
- 2002-12-16 IL IL16205302A patent/IL162053A0/xx unknown
- 2002-12-16 MX MXPA04006027A patent/MXPA04006027A/es not_active Application Discontinuation
- 2002-12-16 KR KR1020047009393A patent/KR100638122B1/ko active IP Right Grant
- 2002-12-16 HU HU0402267A patent/HUP0402267A3/hu not_active Application Discontinuation
- 2002-12-16 TW TW091136276A patent/TWI349553B/zh not_active IP Right Cessation
- 2002-12-16 CN CNB028256271A patent/CN100479823C/zh not_active Expired - Lifetime
- 2002-12-17 US US10/321,208 patent/US20030118634A1/en not_active Abandoned
- 2002-12-19 AR ARP020104997A patent/AR038041A1/es not_active Application Discontinuation
- 2002-12-20 MY MYPI20024837A patent/MY147886A/en unknown
-
2003
- 2003-01-06 PE PE2003000007A patent/PE20030743A1/es not_active Application Discontinuation
-
2004
- 2004-05-19 IL IL162053A patent/IL162053A/en active IP Right Grant
- 2004-05-24 ZA ZA2004/04007A patent/ZA200404007B/en unknown
- 2004-06-15 MA MA27736A patent/MA27157A1/fr unknown
- 2004-07-20 NO NO20043113A patent/NO340249B1/no not_active IP Right Cessation
-
2006
- 2006-06-30 HK HK06107438.9A patent/HK1087039A1/xx not_active IP Right Cessation
-
2007
- 2007-03-20 US US11/725,896 patent/US20070166237A1/en not_active Abandoned
-
2008
- 2008-03-20 US US12/077,623 patent/US20080214505A1/en not_active Abandoned
- 2008-06-27 US US12/163,278 patent/US20080260827A1/en not_active Abandoned
- 2008-06-27 US US12/163,155 patent/US20080261924A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |