ATE441653T1 - Phosphorenthaltende verbindugnen mit antithrombitische wirkung - Google Patents
Phosphorenthaltende verbindugnen mit antithrombitische wirkungInfo
- Publication number
- ATE441653T1 ATE441653T1 AT02770366T AT02770366T ATE441653T1 AT E441653 T1 ATE441653 T1 AT E441653T1 AT 02770366 T AT02770366 T AT 02770366T AT 02770366 T AT02770366 T AT 02770366T AT E441653 T1 ATE441653 T1 AT E441653T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- antithrombitic
- effect
- containing compounds
- phosphorus containing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 title 1
- 229910052698 phosphorus Inorganic materials 0.000 title 1
- 239000011574 phosphorus Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000012453 solvate Substances 0.000 abstract 3
- 102000003847 Carboxypeptidase B2 Human genes 0.000 abstract 2
- 108090000201 Carboxypeptidase B2 Proteins 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0103272A SE0103272D0 (sv) | 2001-09-28 | 2001-09-28 | Chemical compounds |
| PCT/SE2002/001737 WO2003027128A1 (en) | 2001-09-28 | 2002-09-23 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE441653T1 true ATE441653T1 (de) | 2009-09-15 |
Family
ID=20285515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02770366T ATE441653T1 (de) | 2001-09-28 | 2002-09-23 | Phosphorenthaltende verbindugnen mit antithrombitische wirkung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7375121B2 (de) |
| EP (1) | EP1432718B1 (de) |
| JP (1) | JP2005503442A (de) |
| AT (1) | ATE441653T1 (de) |
| DE (1) | DE60233578D1 (de) |
| SE (1) | SE0103272D0 (de) |
| WO (1) | WO2003027128A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1332964C (zh) | 2002-03-21 | 2007-08-22 | 舍林股份公司 | 血浆羧肽酶b抑制剂 |
| CA2741783A1 (en) | 2008-10-29 | 2010-05-06 | Taisho Pharmaceutical Co., Ltd. | Compounds having tafia inhibitory activity |
| WO2014198620A1 (en) | 2013-06-10 | 2014-12-18 | Sanofi | Macrocyclic urea derivatives as inhibitors of tafia, their preparation and their use as pharmaceuticals |
| FR3046793B1 (fr) * | 2016-01-14 | 2018-01-05 | Les Laboratoires Servier | Nouveaux derives de phosphinanes et azaphosphinanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6046180A (en) * | 1996-06-17 | 2000-04-04 | Guilford Pharmaceuticals Inc. | NAALADase inhibitors |
| SE9901573D0 (sv) | 1999-05-03 | 1999-05-03 | Astra Ab | New compounds |
| SE9901572D0 (sv) | 1999-05-03 | 1999-05-03 | Astra Ab | New compounds |
| AR023819A1 (es) | 1999-05-03 | 2002-09-04 | Astrazeneca Ab | FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION |
| JP3400798B2 (ja) | 1999-09-14 | 2003-04-28 | 明治製菓株式会社 | カルボキシペプチダーゼｂ阻害活性を有するホスホン酸誘導体 |
| WO2002014285A1 (en) | 2000-08-17 | 2002-02-21 | Pfizer Limited | Substituted imidazoles as tafia inhibitors |
-
2001
- 2001-09-28 SE SE0103272A patent/SE0103272D0/xx unknown
-
2002
- 2002-09-23 AT AT02770366T patent/ATE441653T1/de not_active IP Right Cessation
- 2002-09-23 US US10/489,530 patent/US7375121B2/en not_active Expired - Fee Related
- 2002-09-23 DE DE60233578T patent/DE60233578D1/de not_active Expired - Fee Related
- 2002-09-23 EP EP02770366A patent/EP1432718B1/de not_active Expired - Lifetime
- 2002-09-23 WO PCT/SE2002/001737 patent/WO2003027128A1/en not_active Ceased
- 2002-09-23 JP JP2003530715A patent/JP2005503442A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003027128A1 (en) | 2003-04-03 |
| SE0103272D0 (sv) | 2001-09-28 |
| EP1432718B1 (de) | 2009-09-02 |
| US20040248852A1 (en) | 2004-12-09 |
| DE60233578D1 (de) | 2009-10-15 |
| US7375121B2 (en) | 2008-05-20 |
| JP2005503442A (ja) | 2005-02-03 |
| EP1432718A1 (de) | 2004-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |