PL369669A1 - Sposób oczyszczania i/lub izolacji biologicznie czynnego czynnika stymulującego kolonie granulocytów - Google Patents

Sposób oczyszczania i/lub izolacji biologicznie czynnego czynnika stymulującego kolonie granulocytów

Info

Publication number
PL369669A1
PL369669A1 PL02369669A PL36966902A PL369669A1 PL 369669 A1 PL369669 A1 PL 369669A1 PL 02369669 A PL02369669 A PL 02369669A PL 36966902 A PL36966902 A PL 36966902A PL 369669 A1 PL369669 A1 PL 369669A1
Authority
PL
Poland
Prior art keywords
csf
biologically active
isolation
stimulating factor
colony stimulating
Prior art date
Application number
PL02369669A
Other languages
English (en)
Other versions
PL207775B1 (pl
Inventor
Porekar Vladka Gaberc
Viktor Menart
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of PL369669A1 publication Critical patent/PL369669A1/pl
Publication of PL207775B1 publication Critical patent/PL207775B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
PL369669A 2001-12-19 2002-12-05 Sposób izolowania biologicznie czynnego poprawnie zwiniętego czynnika stymulującego kolonie granulocytów (G-CSF) PL207775B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200100322A SI21102A (sl) 2001-12-19 2001-12-19 Postopek za izolacijo biološko aktivnega granulocitne kolonije stimulirajočega dejavnika
PCT/EP2002/013810 WO2003051922A1 (en) 2001-12-19 2002-12-05 Process for the purification and/or isolation of biologically active granulocyte colony stimulating factor

Publications (2)

Publication Number Publication Date
PL369669A1 true PL369669A1 (pl) 2005-05-02
PL207775B1 PL207775B1 (pl) 2011-01-31

Family

ID=20433022

Family Applications (1)

Application Number Title Priority Date Filing Date
PL369669A PL207775B1 (pl) 2001-12-19 2002-12-05 Sposób izolowania biologicznie czynnego poprawnie zwiniętego czynnika stymulującego kolonie granulocytów (G-CSF)

Country Status (22)

Country Link
US (1) US20050159589A1 (pl)
EP (2) EP2053061A1 (pl)
JP (1) JP4454311B2 (pl)
KR (1) KR20040071212A (pl)
CN (1) CN1606568A (pl)
AT (1) ATE423136T1 (pl)
AU (1) AU2002366275B2 (pl)
BR (1) BR0215191A (pl)
CA (1) CA2469984C (pl)
DE (1) DE60231243D1 (pl)
HK (1) HK1064681A1 (pl)
HR (1) HRP20040572A2 (pl)
HU (1) HUP0402547A3 (pl)
IL (2) IL162448A0 (pl)
MX (1) MXPA04006076A (pl)
NO (1) NO20042967L (pl)
NZ (1) NZ533305A (pl)
PL (1) PL207775B1 (pl)
RU (1) RU2358980C2 (pl)
SI (2) SI21102A (pl)
WO (1) WO2003051922A1 (pl)
ZA (1) ZA200404291B (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI21273A (sl) * 2002-07-31 2004-02-29 LEK farmacevtska dru�ba d.d. Priprava inkluzijskih teles z visokim deležem pravilno zvitega prekurzorja heterolognega proteina
ATE322506T1 (de) * 2004-01-19 2006-04-15 Ares Trading Sa Verfahren zur reinigung von in bakterien exprimierten proteinen
EP1803464A4 (en) * 2004-09-17 2009-09-09 Cellgentech Inc TOPICAL PREPARATION FOR THE TREATMENT OF SKIN DISEASES
CA2597795A1 (en) * 2005-02-15 2006-08-24 Apollo Life Sciences Limited A molecule and chimeric molecules thereof
EP1869078A2 (en) * 2005-03-17 2007-12-26 Zenotech Laboratories Limited Process for the purification of recombinant granulocyte-colony stimulating factor
DE102005033250A1 (de) * 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
DE202006020194U1 (de) 2006-03-01 2007-12-06 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
EP1878739A1 (en) * 2006-07-14 2008-01-16 LEK Pharmaceuticals D.D. One step IMAC (MCAC) purification of proteins
WO2008096370A2 (en) * 2007-02-05 2008-08-14 Natco Pharma Limited An efficient and novel purification method of recombinant hg-csf
MX2010002448A (es) 2007-08-27 2010-10-04 Biogenerix Ag Formulacion liquida del g-csf conjugado.
JP2009073819A (ja) * 2007-08-29 2009-04-09 Fujifilm Corp 生理活性物質の精製方法
JP2012530131A (ja) * 2009-06-16 2012-11-29 ルピン・リミテッド 組み換えヒト顆粒球コロニー刺激因子の精製のための方法
EP2445924B2 (en) 2009-06-25 2023-12-13 Amgen Inc. Capture purification processes for proteins expressed in a non-mammalian system
US9453045B2 (en) * 2010-03-30 2016-09-27 Octapharma Ag Process for the purification of a growth factor protein
WO2012135415A1 (en) 2011-03-29 2012-10-04 Glaxosmithkline Llc Buffer system for protein purification
CN103215340A (zh) * 2012-01-19 2013-07-24 江苏粒福特生物科技有限公司 一种新颖的粒细胞制备及其抗癌活性检测方法
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására
HUP1200172A2 (en) 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61227526A (ja) 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
EP0215126B1 (en) 1985-02-08 1991-07-31 Chugai Seiyaku Kabushiki Kaisha Human granulocyte colony stimulating factor
US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
DK203187A (da) 1986-04-22 1987-10-23 Immunex Corp Human g-csf proteinekspression
US5055555A (en) 1989-01-05 1991-10-08 Helmut Sassenfeld Purification of G-CSF
US5169936A (en) 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
US5932102A (en) 1998-01-12 1999-08-03 Schering Corporation Immobilized metal, affinity chromatography
FR2796071B1 (fr) * 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes

Also Published As

Publication number Publication date
SI1458757T1 (sl) 2009-10-31
HK1064681A1 (en) 2005-02-04
HUP0402547A3 (en) 2010-01-28
EP2053061A1 (en) 2009-04-29
CA2469984C (en) 2014-05-20
NZ533305A (en) 2005-11-25
AU2002366275B2 (en) 2009-04-02
EP1458757B1 (en) 2009-02-18
US20050159589A1 (en) 2005-07-21
MXPA04006076A (es) 2005-02-24
RU2358980C2 (ru) 2009-06-20
DE60231243D1 (de) 2009-04-02
KR20040071212A (ko) 2004-08-11
HUP0402547A2 (hu) 2005-03-29
HRP20040572A2 (en) 2005-06-30
CA2469984A1 (en) 2003-06-26
BR0215191A (pt) 2004-11-16
WO2003051922A1 (en) 2003-06-26
CN1606568A (zh) 2005-04-13
RU2004121982A (ru) 2005-04-20
SI21102A (sl) 2003-06-30
PL207775B1 (pl) 2011-01-31
JP2005525304A (ja) 2005-08-25
AU2002366275A1 (en) 2003-06-30
IL162448A0 (en) 2005-11-20
NO20042967L (no) 2004-09-07
ZA200404291B (en) 2005-08-05
EP1458757A1 (en) 2004-09-22
ATE423136T1 (de) 2009-03-15
IL162448A (en) 2010-12-30
JP4454311B2 (ja) 2010-04-21

Similar Documents

Publication Publication Date Title
HK1064681A1 (en) Process for the purification and/or isolation of biologically active granulocyte colony stimulating factor
PL1753778T3 (pl) Sposób oczyszczania erytropoetyny
SI1492878T1 (sl) Postopek za pripravo Ĺľelenega profila gliko-izoform eritropoietina
EP1273592B1 (en) Process for the purification of interferon proteins through cationic exchange chromatography
DE60014047D1 (de) Verfahren zur reinigung von milchsäure auf industrieller basis
KR960007612A (ko) 재조합 사람 혈청 알부민의 정제방법
CA2248006A1 (en) Activated linkers and methods for making and purifying the same
ATE403671T1 (de) Methoden zur aufreinigung von rekombinatem humanem erythropoietin aus zellkulturüberständen
IL175350A0 (en) Method for the production of statins
DK1268399T3 (da) Fremgangsmåde til separering af en basisk aminosyre fra fermenteringsvæske
AU3273200A (en) Ion exchange chromatographic separation of glp-1 and related peptides
EP1714982A3 (en) Methods for purifying highly anionic proteins
ATE247665T1 (de) Kombinierter prozess zur reinigung von vancomycin hydrochlorid
AU2003302418A1 (en) Method and apparatus for concentration and purification of nucleic acid
DK0383645T3 (da) Fremgangsmåde til fremstilling af antihæmofilifaktor (FVIIIc) med meget høj renhed
DE602004026048D1 (de) Verfahren zur reinigung des modifizierten hauptallergens von milben
RS20050355A (en) Process for the purification of tnf- binding proteins using imac
RU92004035A (ru) Способ получения адсорбента
EP1178114A3 (en) Heat-stable d-aminoacylase
TW200519123A (en) A novel process to recover and purify acarbose from fermentation broth
AU2001287739A1 (en) Process for the purification of epi-hne proteins
Pliura et al. Displacement chromatography process
KR930013133A (ko) 5'-이노신산 함유액의 정제 방법 (i)