PL367086A1 - Pochodne dihydrobenzo [b] [1,4] diazepin-2-onu jako antagoniści I mGluR2 - Google Patents
Pochodne dihydrobenzo [b] [1,4] diazepin-2-onu jako antagoniści I mGluR2Info
- Publication number
- PL367086A1 PL367086A1 PL02367086A PL36708602A PL367086A1 PL 367086 A1 PL367086 A1 PL 367086A1 PL 02367086 A PL02367086 A PL 02367086A PL 36708602 A PL36708602 A PL 36708602A PL 367086 A1 PL367086 A1 PL 367086A1
- Authority
- PL
- Poland
- Prior art keywords
- diazepin
- benzo
- dihydro
- derivatives
- mglur2 antagonists
- Prior art date
Links
- AZIZBYRGIGKTLW-UHFFFAOYSA-N 1,4-diazepin-2-one Chemical class O=C1C=NC=CC=N1 AZIZBYRGIGKTLW-UHFFFAOYSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01109126 | 2001-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL367086A1 true PL367086A1 (pl) | 2005-02-21 |
Family
ID=8177127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02367086A PL367086A1 (pl) | 2001-04-12 | 2002-04-02 | Pochodne dihydrobenzo [b] [1,4] diazepin-2-onu jako antagoniści I mGluR2 |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US6548495B2 (pl) |
| EP (1) | EP1379522B1 (pl) |
| JP (1) | JP4043953B2 (pl) |
| KR (1) | KR100566178B1 (pl) |
| CN (1) | CN1268626C (pl) |
| AR (1) | AR035456A1 (pl) |
| AT (1) | ATE287883T1 (pl) |
| AU (1) | AU2002310912B2 (pl) |
| BG (1) | BG108253A (pl) |
| BR (1) | BR0208887A (pl) |
| CA (1) | CA2441771C (pl) |
| CZ (1) | CZ20033002A3 (pl) |
| DE (1) | DE60202761T2 (pl) |
| DK (1) | DK1379522T3 (pl) |
| EC (1) | ECSP034796A (pl) |
| ES (1) | ES2235044T3 (pl) |
| GT (1) | GT200200072A (pl) |
| HR (1) | HRP20030791B1 (pl) |
| HU (1) | HUP0400991A3 (pl) |
| IL (2) | IL158021A0 (pl) |
| JO (1) | JO2273B1 (pl) |
| MA (1) | MA27011A1 (pl) |
| MX (1) | MXPA03009317A (pl) |
| MY (1) | MY130369A (pl) |
| NO (1) | NO325300B1 (pl) |
| NZ (1) | NZ528345A (pl) |
| PA (1) | PA8543201A1 (pl) |
| PE (1) | PE20021072A1 (pl) |
| PL (1) | PL367086A1 (pl) |
| PT (1) | PT1379522E (pl) |
| RU (1) | RU2270197C2 (pl) |
| SI (1) | SI1379522T1 (pl) |
| SK (1) | SK13692003A3 (pl) |
| UY (1) | UY27259A1 (pl) |
| WO (1) | WO2002083665A1 (pl) |
| YU (1) | YU79103A (pl) |
| ZA (1) | ZA200307242B (pl) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL357433A1 (pl) | 1999-10-15 | 2004-07-26 | F.Hoffmann-La Roche Ag | Pochodne benzodiazepiny |
| DK1651234T3 (da) * | 2003-07-25 | 2008-01-28 | Hoffmann La Roche | Kombination af en mglur2-antagonist og ache-inhibitor til behandling af akutte og/eller kroniske neurologiske lidelser |
| US7459563B2 (en) | 2004-11-05 | 2008-12-02 | Hoffmann-La Roche Inc. | Process for the preparation of isonicotinic acid derivatives |
| TWI417095B (zh) | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途 |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| CN101657432B (zh) | 2007-04-19 | 2013-04-10 | 弗·哈夫曼-拉罗切有限公司 | 二氢-苯并[b][1,4]二氮杂*-2-酮磺酰胺衍生物 |
| KR101520086B1 (ko) | 2007-09-14 | 2015-05-14 | 얀센 파마슈티칼스 인코포레이티드 | １´,３´-이치환된-４-페닐-３,４,５,６-테트라히드로-２ｈ,１´ｈ-[１,４´]비피리디닐-２´-온 |
| KR20100065191A (ko) | 2007-09-14 | 2010-06-15 | 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 | １,３-이치환된 ４-(아릴-ｘ-페닐)-１ｈ-피리딘-２-온 |
| BRPI0816970A2 (pt) * | 2007-09-14 | 2015-03-24 | Ortho Mcneil Janssen Pharm | 1,3-dissubstituídas-4-fenil-1h-piridin-2-onas |
| WO2009062676A2 (en) | 2007-11-14 | 2009-05-22 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| US8691849B2 (en) | 2008-09-02 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
| MX2011003691A (es) | 2008-10-16 | 2011-09-06 | Ortho Mcneil Janssen Pharm | Derivados de indol y benzomorfolina como moduladores de los receptores de glutamato metabotropico. |
| CN102232074B (zh) | 2008-11-28 | 2014-12-03 | 奥梅-杨森制药有限公司 | 作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物 |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| AU2010246609B2 (en) | 2009-05-12 | 2013-09-05 | Addex Pharma S.A. | 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders |
| US8946205B2 (en) | 2009-05-12 | 2015-02-03 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
| PL2649069T3 (pl) | 2010-11-08 | 2016-01-29 | Janssen Pharmaceuticals Inc | Pochodne 1,2,4-triazolo[4,3-a]pirydyny i ich zastosowanie jako dodatnich allosterycznych modulatorów receptorów mGluR2 |
| JP5852665B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | １，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
| AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
| EP2602248A1 (en) | 2011-12-05 | 2013-06-12 | University Of Leicester | Novel pyrrole compounds |
| AU2013336863A1 (en) | 2012-10-23 | 2015-03-19 | F. Hoffmann-La Roche Ag | MGlu2/3 antagonists for the treatment of autistic disorders |
| EP2963043B1 (en) | 2013-02-28 | 2018-05-30 | Eisai R&D Management Co., Ltd. | Tetrahydroimidazo[1,5-d][1,4]oxazepine derivative |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| UA121965C2 (uk) | 2014-01-21 | 2020-08-25 | Янссен Фармацевтика Нв | Комбінації, які містять позитивні алостеричні модулятори або ортостеричні агоністи метаботропного глутаматергічного рецептора 2 підтипу, та їх застосування |
| KR102502485B1 (ko) | 2014-01-21 | 2023-02-21 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
| JP2017513844A (ja) | 2014-04-23 | 2017-06-01 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 知的障害の処置のためのｍＧｌｕ２／３アンタゴニスト |
| CA2950952C (en) * | 2014-06-10 | 2023-01-10 | Sanford-Burnham Medical Research Institute | Metabotropic glutamate receptor negative allosteric modulators (nams) and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU953819A1 (ru) * | 1980-08-25 | 1991-09-23 | Физико-химический институт АН УССР | 1-(Гидразинокарбонил)алкил-1,2-дигидро-3Н-1,4-бенздиазепин-2-оны, обладающие транквилизирующими и противосудорожными свойствами |
| AU6420700A (en) * | 1999-08-05 | 2001-03-05 | Prescient Neuropharma Inc. | Novel 1,4-benzodiazepine compounds and derivatives thereof |
| PL357433A1 (pl) * | 1999-10-15 | 2004-07-26 | F.Hoffmann-La Roche Ag | Pochodne benzodiazepiny |
| HUP0203142A3 (en) * | 1999-10-15 | 2003-03-28 | Hoffmann La Roche | Benzodiazepine derivatives, process for preparation of the compounds, pharmaceutical compositions containing them and their use |
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2002
- 2002-04-02 JP JP2002581420A patent/JP4043953B2/ja not_active Expired - Fee Related
- 2002-04-02 DK DK02735209T patent/DK1379522T3/da active
- 2002-04-02 SK SK1369-2003A patent/SK13692003A3/sk unknown
- 2002-04-02 WO PCT/EP2002/003643 patent/WO2002083665A1/en active IP Right Grant
- 2002-04-02 MX MXPA03009317A patent/MXPA03009317A/es active IP Right Grant
- 2002-04-02 AU AU2002310912A patent/AU2002310912B2/en not_active Ceased
- 2002-04-02 IL IL15802102A patent/IL158021A0/xx unknown
- 2002-04-02 BR BR0208887-8A patent/BR0208887A/pt active Search and Examination
- 2002-04-02 KR KR1020037013398A patent/KR100566178B1/ko not_active Expired - Fee Related
- 2002-04-02 CA CA002441771A patent/CA2441771C/en not_active Expired - Fee Related
- 2002-04-02 RU RU2003130648/04A patent/RU2270197C2/ru not_active IP Right Cessation
- 2002-04-02 CN CNB028078217A patent/CN1268626C/zh not_active Expired - Fee Related
- 2002-04-02 ES ES02735209T patent/ES2235044T3/es not_active Expired - Lifetime
- 2002-04-02 NZ NZ528345A patent/NZ528345A/en unknown
- 2002-04-02 DE DE60202761T patent/DE60202761T2/de not_active Expired - Lifetime
- 2002-04-02 SI SI200230075T patent/SI1379522T1/xx unknown
- 2002-04-02 AT AT02735209T patent/ATE287883T1/de active
- 2002-04-02 EP EP02735209A patent/EP1379522B1/en not_active Expired - Lifetime
- 2002-04-02 YU YU79103A patent/YU79103A/sh unknown
- 2002-04-02 PL PL02367086A patent/PL367086A1/pl not_active Application Discontinuation
- 2002-04-02 PT PT02735209T patent/PT1379522E/pt unknown
- 2002-04-02 HU HU0400991A patent/HUP0400991A3/hu not_active Application Discontinuation
- 2002-04-02 HR HR20030791A patent/HRP20030791B1/xx not_active IP Right Cessation
- 2002-04-02 CZ CZ20033002A patent/CZ20033002A3/cs unknown
- 2002-04-03 US US10/116,597 patent/US6548495B2/en not_active Expired - Lifetime
- 2002-04-09 PA PA20028543201A patent/PA8543201A1/es unknown
- 2002-04-10 PE PE2002000299A patent/PE20021072A1/es not_active Application Discontinuation
- 2002-04-10 AR ARP020101313A patent/AR035456A1/es not_active Application Discontinuation
- 2002-04-10 JO JO200233A patent/JO2273B1/en active
- 2002-04-11 MY MYPI20021346A patent/MY130369A/en unknown
- 2002-04-11 UY UY27259A patent/UY27259A1/es not_active Application Discontinuation
- 2002-04-11 GT GT200200072A patent/GT200200072A/es unknown
-
2003
- 2003-09-16 ZA ZA200307242A patent/ZA200307242B/en unknown
- 2003-09-18 IL IL158021A patent/IL158021A/en not_active IP Right Cessation
- 2003-10-08 NO NO20034496A patent/NO325300B1/no unknown
- 2003-10-08 MA MA27345A patent/MA27011A1/fr unknown
- 2003-10-08 EC EC2003004796A patent/ECSP034796A/es unknown
- 2003-10-10 BG BG108253A patent/BG108253A/bg unknown
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