PL3639849T3 - Szczepionka na bazie atenuowanego wirusa afrykańskiego pomoru świń - Google Patents

Szczepionka na bazie atenuowanego wirusa afrykańskiego pomoru świń

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Publication number
PL3639849T3
PL3639849T3 PL19192963.7T PL19192963T PL3639849T3 PL 3639849 T3 PL3639849 T3 PL 3639849T3 PL 19192963 T PL19192963 T PL 19192963T PL 3639849 T3 PL3639849 T3 PL 3639849T3
Authority
PL
Poland
Prior art keywords
affican
fever virus
swine fever
based vaccine
vaccine
Prior art date
Application number
PL19192963.7T
Other languages
English (en)
Inventor
Charles Abrams
Ana Luisa REIS
Chris NETHERTON
Linda DIXON
Dave Chapman
Pedro SANCHEZ-CORDON
Original Assignee
The Pirbright Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Pirbright Institute filed Critical The Pirbright Institute
Publication of PL3639849T3 publication Critical patent/PL3639849T3/pl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12061Methods of inactivation or attenuation
    • C12N2710/12062Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL19192963.7T 2014-06-19 2015-06-19 Szczepionka na bazie atenuowanego wirusa afrykańskiego pomoru świń PL3639849T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1410971.4A GB201410971D0 (en) 2014-06-19 2014-06-19 Vaccine

Publications (1)

Publication Number Publication Date
PL3639849T3 true PL3639849T3 (pl) 2025-11-24

Family

ID=51409865

Family Applications (2)

Application Number Title Priority Date Filing Date
PL19192963.7T PL3639849T3 (pl) 2014-06-19 2015-06-19 Szczepionka na bazie atenuowanego wirusa afrykańskiego pomoru świń
PL15733494T PL3157550T3 (pl) 2014-06-19 2015-06-19 Szczepionka na bazie atenuowanego wirusa afrykańskiego pomoru świń

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL15733494T PL3157550T3 (pl) 2014-06-19 2015-06-19 Szczepionka na bazie atenuowanego wirusa afrykańskiego pomoru świń

Country Status (12)

Country Link
US (2) US10507237B2 (pl)
EP (2) EP3157550B1 (pl)
CN (1) CN106459931B (pl)
AP (1) AP2016009664A0 (pl)
EA (1) EA035441B1 (pl)
ES (2) ES2750960T3 (pl)
GB (1) GB201410971D0 (pl)
HU (1) HUE045815T2 (pl)
PL (2) PL3639849T3 (pl)
UA (1) UA121217C2 (pl)
WO (1) WO2015193685A1 (pl)
ZA (1) ZA201608257B (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201410971D0 (en) 2014-06-19 2014-08-06 Pirbright Inst The Vaccine
RU2607791C1 (ru) * 2016-01-21 2017-01-10 Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Российской академии сельскохозяйственных наук Аттенуированный штамм "СКА-2015 ВНИИВВиМ" вируса африканской чумы свиней VIII серотипа для вирусологических и молекулярно-генетических исследований
US9808520B1 (en) * 2016-07-01 2017-11-07 The United States Of America As Represented By The Secretary Of Agriculture Rationally developed african swine fever attenuated virus strain protects against challenge with parental virus georgia 2007 isolate
WO2020049194A1 (es) * 2018-09-03 2020-03-12 Universidad Complutense De Madrid (Ucm) Virus vacunal sus scrofa frente a la peste porcina africana (armenia/07) y derivados del genotipo ii)
EP3946445A2 (en) 2019-03-27 2022-02-09 Boehringer Ingelheim Vetmedica GmbH Immunogenic compositions and vaccines comprising african swine fever virus peptides and proteins and uses thereof
CN110093324B (zh) * 2019-04-26 2020-02-18 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 基因缺失的减毒非洲猪瘟病毒及其作为疫苗的应用
PH12021551677A1 (en) 2019-04-26 2022-03-21 Harbin Veterinary Res Institute Chinese Academy Of Agricultural Sciences Attenuated african swine fever virus with deleted gene and use of same as vaccine
CN111926110B (zh) * 2019-05-31 2021-04-27 洛阳普泰生物技术有限公司 非洲猪瘟病毒实时荧光pcr扩增引物对、探针引物、及制备的试剂盒
KR20220042369A (ko) * 2019-07-11 2022-04-05 앱티뮨 바이올로직스, 인코포레이티드 태아 돼지 폐 폐포 마크로파지 세포에서 아프리카 돼지 열병 바이러스를 성장시키기 위한 방법
GB201910794D0 (en) * 2019-07-29 2019-09-11 Pirbright Inst Vaccine
CN110551695A (zh) * 2019-08-14 2019-12-10 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 非洲猪瘟病毒四基因缺失弱毒株及其应用
CN110499394A (zh) * 2019-09-10 2019-11-26 延安大学 检测非洲猪瘟病毒的lamp引物组、试剂盒及检测方法
JP7382628B2 (ja) * 2019-10-11 2023-11-17 国立研究開発法人農業・食品産業技術総合研究機構 アフリカ豚コレラウイルスの製造方法及び検出方法
CN110878377B (zh) * 2019-11-06 2023-08-22 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 非洲猪瘟病毒强弱毒荧光定量pcr鉴别诊断试剂盒
CN110699489B (zh) * 2019-11-12 2020-12-22 南宁众册生物科技有限公司 非洲猪瘟病毒cd2v基因的实时荧光pcr检测引物探针组、试剂盒及方法
CN110791591B (zh) * 2019-11-18 2023-06-23 华南农业大学 一种区分非洲猪瘟病毒野毒株与双基因缺失疫苗株的lamp检测引物及试剂盒
CN112831598B (zh) * 2019-11-22 2022-12-20 洛阳普泰生物技术有限公司 用于非洲猪瘟病毒鉴别检验的实时荧光pcr扩增引物对、探针引物、及制备的试剂盒
CN113122654A (zh) * 2019-12-30 2021-07-16 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 非洲猪瘟病毒的检测靶标以及荧光定量pcr检测引物
JP2023516713A (ja) * 2020-03-06 2023-04-20 ザ パーブライト インスティチュート アフリカ豚熱ウイルス感染に対するワクチン
CN111593028A (zh) * 2020-04-15 2020-08-28 中国农业科学院兰州兽医研究所 一种缺失mgf360-9l基因的非洲猪瘟病毒减毒株及其应用
CN112063634A (zh) * 2020-05-01 2020-12-11 中国农业科学院兰州兽医研究所 一种基因缺失的减毒非洲猪瘟病毒株及应用
CN111748563A (zh) * 2020-07-10 2020-10-09 中国农业科学院兰州兽医研究所 非洲猪瘟基因缺失弱毒株的构建及其作为疫苗的应用
CN111676327B (zh) * 2020-07-21 2021-05-14 河南省农业科学院 非洲猪瘟病毒野毒感染与基因缺失毒株双重荧光定量pcr检测组合物、方法及试剂盒
CN113929746B (zh) * 2020-08-26 2023-07-25 中国农业科学院兰州兽医研究所 一类促进猪机体产生广谱性免疫应答的多肽及其应用
CN111925996A (zh) * 2020-08-27 2020-11-13 军事科学院军事医学研究院军事兽医研究所 一种非洲猪瘟基因缺失减毒及其活疫苗
CN111996175B (zh) * 2020-09-04 2023-11-21 军事科学院军事医学研究院军事兽医研究所 缺失e66l、i267l基因的非洲猪瘟减毒及活疫苗
US11766476B2 (en) * 2020-12-22 2023-09-26 The United States Of America, As Represented By The Secretary Of Agriculture Genomic deletion in African swine fever vaccine allowing efficient growth in stable cell lines
US20240053340A1 (en) 2020-12-24 2024-02-15 Intervet Inc. African swine fever diva immunoassay
EP4036226A1 (en) * 2021-02-02 2022-08-03 Agence Nationale chargée de la Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail Attenuated african swine fever virus and its use as a vaccine
CN113462817A (zh) * 2021-07-13 2021-10-01 四川农业大学 检测非洲猪瘟病毒衣壳完整性的pcr引物、探针、试剂盒及检测方法
CN114107228B (zh) * 2021-11-11 2023-06-13 中国农业科学院兰州兽医研究所 缺失十二个基因的减毒非洲猪瘟病毒株的构建及其作为疫苗的应用
CN117701509B (zh) * 2023-11-20 2024-05-28 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 一种非洲猪瘟病毒传代致弱毒株与基于该毒株的疫苗

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US20020086427A1 (en) * 2000-03-23 2002-07-04 Leiden Jeffrey M. Inducible eukaryotic expression system that regulates protein translation
US8133495B2 (en) * 2007-05-22 2012-03-13 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever virus
CN103172749B (zh) * 2013-02-01 2014-10-08 广州谱泰生物技术有限公司 一种非洲猪瘟蛋白工程疫苗的制备
GB201410971D0 (en) 2014-06-19 2014-08-06 Pirbright Inst The Vaccine

Also Published As

Publication number Publication date
HUE045815T2 (hu) 2020-01-28
ZA201608257B (en) 2024-04-24
GB201410971D0 (en) 2014-08-06
EP3157550A1 (en) 2017-04-26
EA201692509A1 (ru) 2017-05-31
UA121217C2 (uk) 2020-04-27
PL3157550T3 (pl) 2020-03-31
EP3157550B1 (en) 2019-08-28
AP2016009664A0 (en) 2016-12-31
CN106459931B (zh) 2020-10-13
US11331383B2 (en) 2022-05-17
US20170136114A1 (en) 2017-05-18
EP3639849C0 (en) 2025-07-30
CN106459931A (zh) 2017-02-22
US20200129609A1 (en) 2020-04-30
ES3046674T3 (en) 2025-12-02
EA035441B1 (ru) 2020-06-17
ES2750960T3 (es) 2020-03-30
WO2015193685A1 (en) 2015-12-23
US10507237B2 (en) 2019-12-17
EP3639849A1 (en) 2020-04-22
EP3639849B1 (en) 2025-07-30

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