PL3589606T3 - Dekarboksylowanie pochodnych kwasu alfa-halogenoakrylowego katalizowane metalem przejściowym - Google Patents

Dekarboksylowanie pochodnych kwasu alfa-halogenoakrylowego katalizowane metalem przejściowym

Info

Publication number
PL3589606T3
PL3589606T3 PL18708368.8T PL18708368T PL3589606T3 PL 3589606 T3 PL3589606 T3 PL 3589606T3 PL 18708368 T PL18708368 T PL 18708368T PL 3589606 T3 PL3589606 T3 PL 3589606T3
Authority
PL
Poland
Prior art keywords
protodecarboxylation
catalyzed
halo
alpha
acrylic acid
Prior art date
Application number
PL18708368.8T
Other languages
English (en)
Inventor
Ivan N. Volchkov
Jonathan Timothy Reeves
Mai Thi Quynh Dang
Thomas Armin Hampel
Sandra Koch
Fredrik Lars Nordstrom
Carsten Reichel
Marvin SCHOERER
Christian Stange
Li Zhong
Uwe Johannes ZIMMERMANN
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of PL3589606T3 publication Critical patent/PL3589606T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/72Copper
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/20Carbon compounds
    • B01J27/232Carbonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
PL18708368.8T 2017-03-01 2018-02-22 Dekarboksylowanie pochodnych kwasu alfa-halogenoakrylowego katalizowane metalem przejściowym PL3589606T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762465398P 2017-03-01 2017-03-01
US201762512777P 2017-05-31 2017-05-31
PCT/EP2018/054428 WO2018158140A1 (en) 2017-03-01 2018-02-22 TRANSITION METAL-CATALYZED PROTODECARBOXYLATION OF α-HALO-ACRYLIC ACID DERIVATIVES

Publications (1)

Publication Number Publication Date
PL3589606T3 true PL3589606T3 (pl) 2024-03-04

Family

ID=61557253

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18708368.8T PL3589606T3 (pl) 2017-03-01 2018-02-22 Dekarboksylowanie pochodnych kwasu alfa-halogenoakrylowego katalizowane metalem przejściowym

Country Status (17)

Country Link
US (3) US10252994B2 (pl)
EP (1) EP3589606B1 (pl)
JP (1) JP7145872B2 (pl)
KR (1) KR102550845B1 (pl)
CN (1) CN110366547B (pl)
AU (1) AU2018226955B2 (pl)
BR (1) BR112019017309B1 (pl)
CA (1) CA3053869A1 (pl)
CL (1) CL2019002499A1 (pl)
DK (1) DK3589606T3 (pl)
ES (1) ES2965478T3 (pl)
HU (1) HUE064755T2 (pl)
MX (1) MX2019010311A (pl)
NZ (1) NZ755847A (pl)
PH (1) PH12019501980A1 (pl)
PL (1) PL3589606T3 (pl)
WO (1) WO2018158140A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020125776A1 (zh) * 2018-12-20 2020-06-25 山东丹红制药有限公司 式(iv)化合物的工艺路线、晶型及其制备方法
WO2021262684A1 (en) * 2020-06-22 2021-12-30 Pmv Pharmaceuticals, Inc. METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
CN112341373B (zh) * 2020-11-30 2022-04-08 山东嘉成医药科技有限公司 一种酞丁安的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE259803C (pl)
DD259803A1 (de) 1979-11-30 1988-09-07 Akad Wissenschaften Ddr Verfahren zur herstellung von 5-(2-fluorvinyl-)pyrimidinen
CN1874990B (zh) * 2003-11-07 2011-06-29 住友化学株式会社 3,3-二甲基-2-(1-丙烯基)环丙烷甲酸酯的制备方法
CN1921841A (zh) * 2004-02-25 2007-02-28 拉卓拉药物公司 用于治疗疾病的胺和酰胺类化合物
WO2005082343A2 (en) 2004-02-25 2005-09-09 La Jolla Pharmaceutical Company Amines and amides for the treatment of diseases
WO2006094201A2 (en) 2005-03-02 2006-09-08 La Jolla Pharmaceutical Company Semicarbazide-sensitive amide oxidase inhibitors
US20070293548A1 (en) * 2006-03-31 2007-12-20 Wang Eric Y Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases
US8426587B2 (en) * 2007-11-21 2013-04-23 Pharmaxis Ltd. Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor
PT2430002E (pt) * 2009-05-15 2013-09-11 Sanofi Sa Processo para a preparação de um composto útil como um inibidor de tafia
DK2844637T5 (en) * 2012-05-02 2018-08-13 Boehringer Ingelheim Int SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS BY SSAO AND USES THEREOF

Also Published As

Publication number Publication date
HUE064755T2 (hu) 2024-04-28
US10654803B2 (en) 2020-05-19
DK3589606T3 (da) 2024-01-02
AU2018226955B2 (en) 2021-02-18
MX2019010311A (es) 2020-01-20
US10252994B2 (en) 2019-04-09
US20200231544A1 (en) 2020-07-23
WO2018158140A1 (en) 2018-09-07
JP2020509034A (ja) 2020-03-26
BR112019017309A2 (pt) 2020-03-31
BR112019017309B1 (pt) 2022-11-29
EP3589606A1 (en) 2020-01-08
ES2965478T3 (es) 2024-04-15
CL2019002499A1 (es) 2020-01-31
NZ755847A (en) 2021-12-24
US20190177273A1 (en) 2019-06-13
CN110366547A (zh) 2019-10-22
KR20190125394A (ko) 2019-11-06
AU2018226955A1 (en) 2019-08-15
KR102550845B1 (ko) 2023-07-05
EP3589606B1 (en) 2023-09-20
JP7145872B2 (ja) 2022-10-03
CN110366547B (zh) 2023-02-17
CA3053869A1 (en) 2018-09-07
US20180251427A1 (en) 2018-09-06
US11046648B2 (en) 2021-06-29
PH12019501980A1 (en) 2020-09-28

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