PL3555074T3 - Aminopirazole jako selektywne inhibitory kinaz janusowych - Google Patents
Aminopirazole jako selektywne inhibitory kinaz janusowychInfo
- Publication number
- PL3555074T3 PL3555074T3 PL17821530.7T PL17821530T PL3555074T3 PL 3555074 T3 PL3555074 T3 PL 3555074T3 PL 17821530 T PL17821530 T PL 17821530T PL 3555074 T3 PL3555074 T3 PL 3555074T3
- Authority
- PL
- Poland
- Prior art keywords
- aminopyrazoles
- selective inhibitors
- janus kinases
- janus
- kinases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434154P | 2016-12-14 | 2016-12-14 | |
| PCT/EP2017/082529 WO2018108969A1 (en) | 2016-12-14 | 2017-12-13 | Aminopyrazoles as selective janus kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3555074T3 true PL3555074T3 (pl) | 2022-11-07 |
Family
ID=60812050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17821530.7T PL3555074T3 (pl) | 2016-12-14 | 2017-12-13 | Aminopirazole jako selektywne inhibitory kinaz janusowych |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10875847B2 (pl) |
| EP (2) | EP4095135A1 (pl) |
| JP (1) | JP7116063B2 (pl) |
| CN (2) | CN117756789A (pl) |
| AU (1) | AU2017376398B2 (pl) |
| CA (1) | CA3045951A1 (pl) |
| DK (1) | DK3555074T3 (pl) |
| ES (1) | ES2926545T3 (pl) |
| FI (1) | FIC20253009I1 (pl) |
| FR (1) | FR25C1047I1 (pl) |
| NL (1) | NL301349I2 (pl) |
| PL (1) | PL3555074T3 (pl) |
| RU (1) | RU2757218C2 (pl) |
| WO (1) | WO2018108969A1 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113195476A (zh) * | 2018-12-13 | 2021-07-30 | 英特维特国际股份有限公司 | 1-[(3r,4s)-4-氰基四氢吡喃-3-基]-3-[(2-氟-6-甲氧基-4-吡啶基)氨基]吡唑-4-甲酰胺的结晶形式 |
| EP3894403A1 (en) | 2018-12-13 | 2021-10-20 | Intervet International B.V. | Process for preparing 1-[(3r,4s)-4-cyanotetrahydropyran-3-yl]-3-[(2-fluoro-6-methoxy-4-pyridyl)amino]p yrazole-4-carboxamide |
| WO2020118597A1 (en) * | 2018-12-13 | 2020-06-18 | Intervet International B.V. | Process for making 1- [ (3r, 4s) -4-cyanotetrahydropyran-3-yl] -3- [ (2-fluoro-6-methoxy-4-pyridyl) amino] pyrazole-4-carboxamide |
| BR112021021427A2 (pt) | 2019-05-02 | 2021-12-21 | Intervet Int Bv | Processo para a produção de 3-amino-1-[(3r,4s)-4-cianotetrahidropiran-3-il]pirazol-4-carboxilato de etila através de separação quiral de uma mistura racêmica |
| CN114929203A (zh) * | 2019-12-20 | 2022-08-19 | 英特维特国际股份有限公司 | 分散在聚合物基质中的吡唑化合物的药物组合物 |
| CN114829396A (zh) | 2019-12-20 | 2022-07-29 | 英特维特国际股份有限公司 | 用于治疗特应性皮炎的双特异性犬源化抗体和双特异性结合伴体 |
| KR20220119024A (ko) * | 2019-12-20 | 2022-08-26 | 인터벳 인터내셔널 비.브이. | 피라졸 제약 조성물 |
| US12577310B2 (en) | 2020-10-15 | 2026-03-17 | Intervet Inc. | Caninized antibodies to canine interleukin-31 receptor alpha |
| JP2023554665A (ja) | 2020-12-18 | 2023-12-28 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | ホウ素含有ピラゾール化合物、それらを含む組成物、それらの方法及び使用 |
| EP4388006A1 (en) | 2021-08-20 | 2024-06-26 | Intervet International B.V. | Homodimer fusion proteins for treating atopic dermatitis |
| US20250340654A1 (en) | 2021-12-16 | 2025-11-06 | Intervet Inc. | Caninized antibodies to canine interleukin-31 receptor alpha ii |
| EP4452970A1 (en) | 2021-12-24 | 2024-10-30 | Intervet International B.V. | Use of aminopyrazole compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| TW505646B (en) | 1998-06-19 | 2002-10-11 | Pfizer Prod Inc | Pyrrolo [2,3-d] pyrimidine compounds |
| TW200734327A (en) * | 2005-11-03 | 2007-09-16 | Vertex Pharma | Aminopyrimidines useful as kinase inhibitors |
| EP2384326B1 (en) | 2008-08-20 | 2014-04-23 | Zoetis LLC | Pyrrolo[2,3-d]pyrimidine compounds |
| AU2012313094B2 (en) | 2011-09-22 | 2017-02-02 | Intervet International B.V. | Pyrazole carboxamides as janus kinase inhibitors |
| WO2014146246A1 (en) | 2013-03-19 | 2014-09-25 | Merck Sharp & Dohme Corp. | Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors |
| WO2016170009A1 (en) * | 2015-04-21 | 2016-10-27 | Almirall, S.A. | Amino-substituted heterocyclic derivatives as sodium channel inhibitors |
-
2017
- 2017-12-13 CN CN202311769143.4A patent/CN117756789A/zh active Pending
- 2017-12-13 CA CA3045951A patent/CA3045951A1/en active Pending
- 2017-12-13 WO PCT/EP2017/082529 patent/WO2018108969A1/en not_active Ceased
- 2017-12-13 JP JP2019531369A patent/JP7116063B2/ja active Active
- 2017-12-13 US US16/468,548 patent/US10875847B2/en active Active
- 2017-12-13 DK DK17821530.7T patent/DK3555074T3/da active
- 2017-12-13 PL PL17821530.7T patent/PL3555074T3/pl unknown
- 2017-12-13 CN CN201780077566.6A patent/CN110062754B/zh active Active
- 2017-12-13 EP EP22178697.3A patent/EP4095135A1/en not_active Withdrawn
- 2017-12-13 ES ES17821530T patent/ES2926545T3/es active Active
- 2017-12-13 RU RU2019121667A patent/RU2757218C2/ru active
- 2017-12-13 EP EP17821530.7A patent/EP3555074B1/en active Active
- 2017-12-13 AU AU2017376398A patent/AU2017376398B2/en active Active
-
2025
- 2025-11-21 NL NL301349C patent/NL301349I2/nl unknown
- 2025-11-25 FI FIC20253009C patent/FIC20253009I1/fi unknown
- 2025-11-28 FR FR25C1047C patent/FR25C1047I1/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| FIC20253009I1 (fi) | 2025-11-25 |
| RU2019121667A (ru) | 2021-01-15 |
| AU2017376398A1 (en) | 2019-05-30 |
| AU2017376398B2 (en) | 2021-07-15 |
| RU2757218C2 (ru) | 2021-10-12 |
| ES2926545T3 (es) | 2022-10-26 |
| NL301349I2 (nl) | 2026-03-02 |
| EP4095135A1 (en) | 2022-11-30 |
| WO2018108969A1 (en) | 2018-06-21 |
| EP3555074B1 (en) | 2022-07-27 |
| CN117756789A (zh) | 2024-03-26 |
| BR112019011835A2 (pt) | 2019-10-22 |
| US10875847B2 (en) | 2020-12-29 |
| RU2019121667A3 (pl) | 2021-02-25 |
| JP2020503288A (ja) | 2020-01-30 |
| CA3045951A1 (en) | 2018-06-21 |
| DK3555074T3 (da) | 2022-10-03 |
| JP7116063B2 (ja) | 2022-08-09 |
| CN110062754B (zh) | 2024-01-02 |
| FR25C1047I1 (fr) | 2026-01-02 |
| EP3555074A1 (en) | 2019-10-23 |
| CN110062754A (zh) | 2019-07-26 |
| US20200115367A1 (en) | 2020-04-16 |
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