PL353245A1 - Kumaryny chalkonowe - Google Patents

Kumaryny chalkonowe

Info

Publication number
PL353245A1
PL353245A1 PL00353245A PL35324500A PL353245A1 PL 353245 A1 PL353245 A1 PL 353245A1 PL 00353245 A PL00353245 A PL 00353245A PL 35324500 A PL35324500 A PL 35324500A PL 353245 A1 PL353245 A1 PL 353245A1
Authority
PL
Poland
Prior art keywords
coumarins
chalcone
cell growth
agents
hydroxyphenyllactate
Prior art date
Application number
PL00353245A
Other languages
English (en)
Inventor
Ezio Bombardelli
Piero Valenti
Original Assignee
Indena S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena S.P.A. filed Critical Indena S.P.A.
Publication of PL353245A1 publication Critical patent/PL353245A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Glass Compositions (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Epoxy Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)
PL00353245A 1999-09-03 2000-08-28 Kumaryny chalkonowe PL353245A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9920908.2A GB9920908D0 (en) 1999-09-03 1999-09-03 Chalcone coumarins
PCT/EP2000/008367 WO2001017984A1 (en) 1999-09-03 2000-08-28 Chalcone coumarins

Publications (1)

Publication Number Publication Date
PL353245A1 true PL353245A1 (pl) 2003-11-03

Family

ID=10860344

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00353245A PL353245A1 (pl) 1999-09-03 2000-08-28 Kumaryny chalkonowe

Country Status (22)

Country Link
US (1) US6767916B2 (pl)
EP (1) EP1212311B1 (pl)
JP (1) JP2003508523A (pl)
KR (1) KR100819574B1 (pl)
CN (1) CN1142927C (pl)
AT (1) ATE235480T1 (pl)
AU (1) AU775083B2 (pl)
CA (1) CA2382112A1 (pl)
CZ (1) CZ2002786A3 (pl)
DE (1) DE60001850T2 (pl)
DK (1) DK1212311T3 (pl)
ES (1) ES2191643T3 (pl)
GB (1) GB9920908D0 (pl)
HK (1) HK1043997B (pl)
HU (1) HUP0202581A3 (pl)
NO (1) NO20021048L (pl)
PL (1) PL353245A1 (pl)
PT (1) PT1212311E (pl)
RU (1) RU2266291C2 (pl)
SE (1) SE1212311T5 (pl)
SK (1) SK3102002A3 (pl)
WO (1) WO2001017984A1 (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL448929A1 (pl) * 2024-06-21 2025-12-22 Instytut Chemii Organicznej Polskiej Akademii Nauk Nowe (kumaryno-7-amino)-acetamidy oraz ich zastosowania

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030229136A1 (en) 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US7638554B2 (en) 2002-04-18 2009-12-29 Sri International Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
CA2611608A1 (en) 2005-06-08 2006-12-14 Temple University - Of The Commonwealth System Of Higher Education 3-acyl coumarins, thiochromones and quinolones and therapeutic uses thereof
CN101041646B (zh) * 2007-04-30 2011-07-20 浙江大学 含氮查耳酮衍生物的制备方法和用途
CN101121706B (zh) * 2007-09-18 2010-11-24 南京中瑞药业有限公司 一种香豆素衍生物及其制备方法和用途
JP5479105B2 (ja) * 2007-11-05 2014-04-23 国立大学法人佐賀大学 新規ユビキリン結合性小分子
EP2601183A1 (en) 2010-08-05 2013-06-12 Council Of Scientific & Industrial Research Coumarin-chalcones as anticancer agents
WO2012174436A1 (en) 2011-06-15 2012-12-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
CN104987328A (zh) * 2012-05-23 2015-10-21 复旦大学 7-氧、硫或氮杂取代香豆素及其衍生物和用途
CN102731457A (zh) * 2012-06-25 2012-10-17 西南石油大学 一种水溶性荧光示踪聚合物及其制备方法
RU2760006C1 (ru) * 2017-11-16 2021-11-22 Дзе Инститьют оф Кансер Рисерч: Ройал Кансер Хоспитал Производное кумарина для лечения или профилактики расстройства пролиферации клеток
CN109293616B (zh) * 2018-09-29 2022-06-21 贵州大学 一种含香豆素查尔酮类衍生物、其制备方法及应用
JP2022547358A (ja) 2019-09-13 2022-11-14 ジ インスティテュート オブ キャンサー リサーチ：ロイヤル キャンサー ホスピタル 治療組成物、組み合わせ、及び使用方法
US11873296B2 (en) 2022-06-07 2024-01-16 Verastem, Inc. Solid forms of a dual RAF/MEK inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2387956A1 (fr) * 1977-04-20 1978-11-17 Unicler Derives de la pyridine et leur preparation
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US5399561A (en) * 1989-09-19 1995-03-21 Allergan, Inc. Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-oxochromanyl, 2-oxothiochromanyl or 2-oxo-1,2,3,4-tetrahydro-quinolinyl group having retinoid-like biological activity
AU7963691A (en) * 1990-05-17 1991-12-10 Baylor College Of Medicine Growth inhibitors and methods of treating cancer and cell proliferative diseases
IT1271301B (it) * 1994-12-20 1997-05-27 Indena Spa Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
US5525625A (en) * 1995-01-24 1996-06-11 Warner-Lambert Company 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL448929A1 (pl) * 2024-06-21 2025-12-22 Instytut Chemii Organicznej Polskiej Akademii Nauk Nowe (kumaryno-7-amino)-acetamidy oraz ich zastosowania

Also Published As

Publication number Publication date
CN1371370A (zh) 2002-09-25
HK1043997B (en) 2003-08-15
KR100819574B1 (ko) 2008-04-04
DE60001850D1 (de) 2003-04-30
SK3102002A3 (en) 2003-10-07
EP1212311A1 (en) 2002-06-12
US20020161036A1 (en) 2002-10-31
HUP0202581A3 (en) 2003-07-28
US6767916B2 (en) 2004-07-27
SE1212311T5 (pl) 2003-06-10
EP1212311B1 (en) 2003-03-26
WO2001017984A1 (en) 2001-03-15
NO20021048D0 (no) 2002-03-01
GB9920908D0 (en) 1999-11-10
SE1212311T3 (pl) 2003-05-06
DE60001850T2 (de) 2003-12-11
HUP0202581A2 (hu) 2002-11-28
AU7648800A (en) 2001-04-10
RU2002108567A (ru) 2004-01-10
CA2382112A1 (en) 2001-03-15
HK1043997A1 (en) 2002-10-04
KR20020030800A (ko) 2002-04-25
NO20021048L (no) 2002-05-03
AU775083B2 (en) 2004-07-15
ATE235480T1 (de) 2003-04-15
CN1142927C (zh) 2004-03-24
ES2191643T3 (es) 2003-09-16
DK1212311T3 (da) 2003-06-23
RU2266291C2 (ru) 2005-12-20
CZ2002786A3 (cs) 2002-06-12
PT1212311E (pt) 2003-08-29
JP2003508523A (ja) 2003-03-04

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Legal Events

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