SE1212311T5 - - Google Patents

Info

Publication number
SE1212311T5
SE1212311T5 SE00965902T SE00965902T SE1212311T5 SE 1212311 T5 SE1212311 T5 SE 1212311T5 SE 00965902 T SE00965902 T SE 00965902T SE 00965902 T SE00965902 T SE 00965902T SE 1212311 T5 SE1212311 T5 SE 1212311T5
Authority
SE
Sweden
Prior art keywords
cell growth
agents
hydroxyphenyllactate
antitumor
analogues
Prior art date
Application number
SE00965902T
Other languages
English (en)
Other versions
SE1212311T3 (xx
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of SE1212311T3 publication Critical patent/SE1212311T3/xx
Publication of SE1212311T5 publication Critical patent/SE1212311T5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Saccharide Compounds (AREA)
  • Glass Compositions (AREA)
SE00965902T 1999-09-03 2000-08-28 SE1212311T5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9920908.2A GB9920908D0 (en) 1999-09-03 1999-09-03 Chalcone coumarins

Publications (2)

Publication Number Publication Date
SE1212311T3 SE1212311T3 (xx) 2003-05-06
SE1212311T5 true SE1212311T5 (xx) 2003-06-10

Family

ID=10860344

Family Applications (1)

Application Number Title Priority Date Filing Date
SE00965902T SE1212311T5 (xx) 1999-09-03 2000-08-28

Country Status (22)

Country Link
US (1) US6767916B2 (xx)
EP (1) EP1212311B1 (xx)
JP (1) JP2003508523A (xx)
KR (1) KR100819574B1 (xx)
CN (1) CN1142927C (xx)
AT (1) ATE235480T1 (xx)
AU (1) AU775083B2 (xx)
CA (1) CA2382112A1 (xx)
CZ (1) CZ2002786A3 (xx)
DE (1) DE60001850T2 (xx)
DK (1) DK1212311T3 (xx)
ES (1) ES2191643T3 (xx)
GB (1) GB9920908D0 (xx)
HK (1) HK1043997B (xx)
HU (1) HUP0202581A3 (xx)
NO (1) NO20021048L (xx)
PL (1) PL353245A1 (xx)
PT (1) PT1212311E (xx)
RU (1) RU2266291C2 (xx)
SE (1) SE1212311T5 (xx)
SK (1) SK3102002A3 (xx)
WO (1) WO2001017984A1 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030229136A1 (en) 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US7638554B2 (en) 2002-04-18 2009-12-29 Sri International Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
CA2611608A1 (en) 2005-06-08 2006-12-14 Temple University - Of The Commonwealth System Of Higher Education 3-acyl coumarins, thiochromones and quinolones and therapeutic uses thereof
CN101041646B (zh) * 2007-04-30 2011-07-20 浙江大学 含氮查耳酮衍生物的制备方法和用途
CN101121706B (zh) * 2007-09-18 2010-11-24 南京中瑞药业有限公司 一种香豆素衍生物及其制备方法和用途
JP5479105B2 (ja) * 2007-11-05 2014-04-23 国立大学法人佐賀大学 新規ユビキリン結合性小分子
EP2601183A1 (en) 2010-08-05 2013-06-12 Council Of Scientific & Industrial Research Coumarin-chalcones as anticancer agents
WO2012174436A1 (en) 2011-06-15 2012-12-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
CN104987328A (zh) * 2012-05-23 2015-10-21 复旦大学 7-氧、硫或氮杂取代香豆素及其衍生物和用途
CN102731457A (zh) * 2012-06-25 2012-10-17 西南石油大学 一种水溶性荧光示踪聚合物及其制备方法
WO2019096397A1 (en) * 2017-11-16 2019-05-23 The Institute Of Cancer Research: Royal Cancer Hospital Coumarin derivative for therapy or prophylaxis of a cell proliferative disorder
CN109293616B (zh) * 2018-09-29 2022-06-21 贵州大学 一种含香豆素查尔酮类衍生物、其制备方法及应用
WO2021047783A1 (en) 2019-09-13 2021-03-18 The Institute Of Cancer Research: Royal Cancer Hospital Vs-6063 in combination with ch5126766 for the treatment of cancer
US11873296B2 (en) 2022-06-07 2024-01-16 Verastem, Inc. Solid forms of a dual RAF/MEK inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2387956A1 (fr) * 1977-04-20 1978-11-17 Unicler Derives de la pyridine et leur preparation
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US5399561A (en) * 1989-09-19 1995-03-21 Allergan, Inc. Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-oxochromanyl, 2-oxothiochromanyl or 2-oxo-1,2,3,4-tetrahydro-quinolinyl group having retinoid-like biological activity
EP0528975A4 (en) * 1990-05-17 1993-09-15 Baylor College Of Medicine Growth inhibitors and methods of treating cancer and cell proliferative diseases
IT1271301B (it) 1994-12-20 1997-05-27 Indena Spa Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
US5525625A (en) * 1995-01-24 1996-06-11 Warner-Lambert Company 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders

Also Published As

Publication number Publication date
PL353245A1 (en) 2003-11-03
US20020161036A1 (en) 2002-10-31
SK3102002A3 (en) 2003-10-07
CZ2002786A3 (cs) 2002-06-12
GB9920908D0 (en) 1999-11-10
NO20021048L (no) 2002-05-03
CN1371370A (zh) 2002-09-25
PT1212311E (pt) 2003-08-29
US6767916B2 (en) 2004-07-27
HUP0202581A3 (en) 2003-07-28
CA2382112A1 (en) 2001-03-15
NO20021048D0 (no) 2002-03-01
DE60001850D1 (de) 2003-04-30
EP1212311A1 (en) 2002-06-12
KR20020030800A (ko) 2002-04-25
ATE235480T1 (de) 2003-04-15
ES2191643T3 (es) 2003-09-16
RU2266291C2 (ru) 2005-12-20
JP2003508523A (ja) 2003-03-04
DE60001850T2 (de) 2003-12-11
HK1043997B (zh) 2003-08-15
EP1212311B1 (en) 2003-03-26
KR100819574B1 (ko) 2008-04-04
HK1043997A1 (en) 2002-10-04
DK1212311T3 (da) 2003-06-23
RU2002108567A (ru) 2004-01-10
SE1212311T3 (xx) 2003-05-06
HUP0202581A2 (hu) 2002-11-28
CN1142927C (zh) 2004-03-24
WO2001017984A1 (en) 2001-03-15
AU775083B2 (en) 2004-07-15
AU7648800A (en) 2001-04-10

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