ATE235480T1 - Chalcon coumarine - Google Patents
Chalcon coumarineInfo
- Publication number
- ATE235480T1 ATE235480T1 AT00965902T AT00965902T ATE235480T1 AT E235480 T1 ATE235480 T1 AT E235480T1 AT 00965902 T AT00965902 T AT 00965902T AT 00965902 T AT00965902 T AT 00965902T AT E235480 T1 ATE235480 T1 AT E235480T1
- Authority
- AT
- Austria
- Prior art keywords
- chalcon
- coumarine
- cell growth
- agents
- hydroxyphenyllactate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Glass Compositions (AREA)
- General Preparation And Processing Of Foods (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
- Fire-Extinguishing Compositions (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9920908.2A GB9920908D0 (en) | 1999-09-03 | 1999-09-03 | Chalcone coumarins |
PCT/EP2000/008367 WO2001017984A1 (en) | 1999-09-03 | 2000-08-28 | Chalcone coumarins |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE235480T1 true ATE235480T1 (de) | 2003-04-15 |
Family
ID=10860344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00965902T ATE235480T1 (de) | 1999-09-03 | 2000-08-28 | Chalcon coumarine |
Country Status (22)
Country | Link |
---|---|
US (1) | US6767916B2 (de) |
EP (1) | EP1212311B1 (de) |
JP (1) | JP2003508523A (de) |
KR (1) | KR100819574B1 (de) |
CN (1) | CN1142927C (de) |
AT (1) | ATE235480T1 (de) |
AU (1) | AU775083B2 (de) |
CA (1) | CA2382112A1 (de) |
CZ (1) | CZ2002786A3 (de) |
DE (1) | DE60001850T2 (de) |
DK (1) | DK1212311T3 (de) |
ES (1) | ES2191643T3 (de) |
GB (1) | GB9920908D0 (de) |
HK (1) | HK1043997B (de) |
HU (1) | HUP0202581A3 (de) |
NO (1) | NO20021048L (de) |
PL (1) | PL353245A1 (de) |
PT (1) | PT1212311E (de) |
RU (1) | RU2266291C2 (de) |
SE (1) | SE1212311T5 (de) |
SK (1) | SK3102002A3 (de) |
WO (1) | WO2001017984A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030229136A1 (en) | 2002-04-18 | 2003-12-11 | Nurulain Zaveri | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents |
US7638554B2 (en) | 2002-04-18 | 2009-12-29 | Sri International | Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents |
US8067461B2 (en) | 2005-06-08 | 2011-11-29 | Temple University-Of The Commonwealth System Of Higher Education | 3-acyl coumarins, thiochromones and quinolones and therapeutic uses thereof |
CN101041646B (zh) * | 2007-04-30 | 2011-07-20 | 浙江大学 | 含氮查耳酮衍生物的制备方法和用途 |
CN101121706B (zh) * | 2007-09-18 | 2010-11-24 | 南京中瑞药业有限公司 | 一种香豆素衍生物及其制备方法和用途 |
WO2009060835A1 (ja) * | 2007-11-05 | 2009-05-14 | Kyoto University | 新規ユビキリン結合性小分子 |
WO2012017454A1 (en) | 2010-08-05 | 2012-02-09 | Council Of Scientific & Industrial Research | Coumarin-chalcones as anticancer agents |
EP3333153A1 (de) | 2011-06-15 | 2018-06-13 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Nuklearrezeptormodulatoren und deren verwendung zur behandlung und prävention von krebs |
CN104987328A (zh) * | 2012-05-23 | 2015-10-21 | 复旦大学 | 7-氧、硫或氮杂取代香豆素及其衍生物和用途 |
CN102731457A (zh) * | 2012-06-25 | 2012-10-17 | 西南石油大学 | 一种水溶性荧光示踪聚合物及其制备方法 |
WO2019096397A1 (en) * | 2017-11-16 | 2019-05-23 | The Institute Of Cancer Research: Royal Cancer Hospital | Coumarin derivative for therapy or prophylaxis of a cell proliferative disorder |
CN109293616B (zh) * | 2018-09-29 | 2022-06-21 | 贵州大学 | 一种含香豆素查尔酮类衍生物、其制备方法及应用 |
JP2022547358A (ja) | 2019-09-13 | 2022-11-14 | ジ インスティテュート オブ キャンサー リサーチ:ロイヤル キャンサー ホスピタル | 治療組成物、組み合わせ、及び使用方法 |
US11873296B2 (en) | 2022-06-07 | 2024-01-16 | Verastem, Inc. | Solid forms of a dual RAF/MEK inhibitor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2387956A1 (fr) * | 1977-04-20 | 1978-11-17 | Unicler | Derives de la pyridine et leur preparation |
US5399561A (en) * | 1989-09-19 | 1995-03-21 | Allergan, Inc. | Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-oxochromanyl, 2-oxothiochromanyl or 2-oxo-1,2,3,4-tetrahydro-quinolinyl group having retinoid-like biological activity |
US5023341A (en) * | 1989-09-19 | 1991-06-11 | Allergan, Inc. | Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity |
JPH05509078A (ja) * | 1990-05-17 | 1993-12-16 | ベイラー カレッジ オブ メディシン | 成長抑制因とガンおよび細胞増殖性疾患措置法 |
IT1271301B (it) * | 1994-12-20 | 1997-05-27 | Indena Spa | Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono |
US5525625A (en) * | 1995-01-24 | 1996-06-11 | Warner-Lambert Company | 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders |
-
1999
- 1999-09-03 GB GBGB9920908.2A patent/GB9920908D0/en not_active Ceased
-
2000
- 2000-08-28 JP JP2001521731A patent/JP2003508523A/ja not_active Withdrawn
- 2000-08-28 RU RU2002108567/04A patent/RU2266291C2/ru not_active IP Right Cessation
- 2000-08-28 WO PCT/EP2000/008367 patent/WO2001017984A1/en active IP Right Grant
- 2000-08-28 AT AT00965902T patent/ATE235480T1/de not_active IP Right Cessation
- 2000-08-28 SE SE00965902T patent/SE1212311T5/xx unknown
- 2000-08-28 PL PL00353245A patent/PL353245A1/xx not_active IP Right Cessation
- 2000-08-28 EP EP00965902A patent/EP1212311B1/de not_active Expired - Lifetime
- 2000-08-28 PT PT00965902T patent/PT1212311E/pt unknown
- 2000-08-28 KR KR1020027002799A patent/KR100819574B1/ko not_active IP Right Cessation
- 2000-08-28 DE DE60001850T patent/DE60001850T2/de not_active Expired - Fee Related
- 2000-08-28 CZ CZ2002786A patent/CZ2002786A3/cs unknown
- 2000-08-28 ES ES00965902T patent/ES2191643T3/es not_active Expired - Lifetime
- 2000-08-28 SK SK310-2002A patent/SK3102002A3/sk unknown
- 2000-08-28 HU HU0202581A patent/HUP0202581A3/hu unknown
- 2000-08-28 CN CNB00812163XA patent/CN1142927C/zh not_active Expired - Fee Related
- 2000-08-28 DK DK00965902T patent/DK1212311T3/da active
- 2000-08-28 AU AU76488/00A patent/AU775083B2/en not_active Ceased
- 2000-08-28 CA CA002382112A patent/CA2382112A1/en not_active Abandoned
-
2002
- 2002-02-15 US US10/075,625 patent/US6767916B2/en not_active Expired - Fee Related
- 2002-03-01 NO NO20021048A patent/NO20021048L/no not_active Application Discontinuation
- 2002-07-30 HK HK02105581.2A patent/HK1043997B/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU7648800A (en) | 2001-04-10 |
HK1043997B (zh) | 2003-08-15 |
DE60001850T2 (de) | 2003-12-11 |
AU775083B2 (en) | 2004-07-15 |
GB9920908D0 (en) | 1999-11-10 |
DK1212311T3 (da) | 2003-06-23 |
EP1212311A1 (de) | 2002-06-12 |
RU2002108567A (ru) | 2004-01-10 |
SE1212311T3 (de) | 2003-05-06 |
CA2382112A1 (en) | 2001-03-15 |
WO2001017984A1 (en) | 2001-03-15 |
KR100819574B1 (ko) | 2008-04-04 |
US6767916B2 (en) | 2004-07-27 |
HUP0202581A3 (en) | 2003-07-28 |
CN1371370A (zh) | 2002-09-25 |
DE60001850D1 (de) | 2003-04-30 |
NO20021048D0 (no) | 2002-03-01 |
HK1043997A1 (en) | 2002-10-04 |
PT1212311E (pt) | 2003-08-29 |
JP2003508523A (ja) | 2003-03-04 |
RU2266291C2 (ru) | 2005-12-20 |
US20020161036A1 (en) | 2002-10-31 |
ES2191643T3 (es) | 2003-09-16 |
CN1142927C (zh) | 2004-03-24 |
HUP0202581A2 (hu) | 2002-11-28 |
KR20020030800A (ko) | 2002-04-25 |
NO20021048L (no) | 2002-05-03 |
PL353245A1 (en) | 2003-11-03 |
SK3102002A3 (en) | 2003-10-07 |
SE1212311T5 (de) | 2003-06-10 |
CZ2002786A3 (cs) | 2002-06-12 |
EP1212311B1 (de) | 2003-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1212311 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |