PL3481942T3 - Sposoby hodowania organoidów - Google Patents

Sposoby hodowania organoidów

Info

Publication number
PL3481942T3
PL3481942T3 PL17742271T PL17742271T PL3481942T3 PL 3481942 T3 PL3481942 T3 PL 3481942T3 PL 17742271 T PL17742271 T PL 17742271T PL 17742271 T PL17742271 T PL 17742271T PL 3481942 T3 PL3481942 T3 PL 3481942T3
Authority
PL
Poland
Prior art keywords
methods
growing organoids
organoids
growing
Prior art date
Application number
PL17742271T
Other languages
English (en)
Inventor
Marianne J ELLIS
Julian CHAUDHURI
Trevor Clive Dale
Original Assignee
Cellesce Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellesce Limited filed Critical Cellesce Limited
Publication of PL3481942T3 publication Critical patent/PL3481942T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062General methods for three-dimensional culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10Mechanical dissociation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/003D culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL17742271T 2016-07-11 2017-07-11 Sposoby hodowania organoidów PL3481942T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1611982.8A GB201611982D0 (en) 2016-07-11 2016-07-11 Cell culture
PCT/GB2017/052026 WO2018011558A1 (en) 2016-07-11 2017-07-11 Methods for culturing organoids
EP17742271.4A EP3481942B1 (en) 2016-07-11 2017-07-11 Methods for culturing organoids

Publications (1)

Publication Number Publication Date
PL3481942T3 true PL3481942T3 (pl) 2022-06-20

Family

ID=56890801

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17742271T PL3481942T3 (pl) 2016-07-11 2017-07-11 Sposoby hodowania organoidów

Country Status (11)

Country Link
US (3) US11401501B2 (pl)
EP (2) EP3481942B1 (pl)
JP (1) JP7123412B2 (pl)
CN (2) CN117402826A (pl)
CA (1) CA3028111A1 (pl)
DK (1) DK3481942T3 (pl)
ES (1) ES2910714T3 (pl)
GB (1) GB201611982D0 (pl)
PL (1) PL3481942T3 (pl)
PT (1) PT3481942T (pl)
WO (1) WO2018011558A1 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
SG10201801654RA (en) 2014-05-28 2018-04-27 Childrens Hospital Med Ct Methods and systems for converting precursor cells into gastric tissues through directed differentiation
AU2015331848B2 (en) 2014-10-17 2022-03-03 Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
CN109415685B (zh) 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
EP3534976A4 (en) 2016-11-04 2020-09-16 Children's Hospital Medical Center PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE
CA3045145A1 (en) 2016-12-05 2018-06-14 Children's Hospital Medical Center Colonic organoids and methods of making and using same
WO2018191673A1 (en) 2017-04-14 2018-10-18 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
JP2020536529A (ja) 2017-10-10 2020-12-17 チルドレンズ ホスピタル メディカル センター 食道組織および/または臓器組成物およびそれを作製する方法
WO2019126626A1 (en) 2017-12-21 2019-06-27 Children's Hospital Medical Center Digitalized human organoids and methods of using same
EP3826652B1 (en) 2018-07-26 2026-02-25 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
EP3849568A4 (en) 2018-09-12 2022-06-15 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
CN109321528A (zh) * 2018-09-18 2019-02-12 梁廷波 中国人B7-H5表达阳性胰腺癌细胞系sipanc-1076建立方法
EP3898944A1 (en) * 2018-12-19 2021-10-27 Regents of the University of Minnesota Methods for generating and using organoids and tissue therein
US20220088085A1 (en) * 2019-02-28 2022-03-24 Public University Corporation Yokohama City University Composition for treating blood coagulation and/or complement disorders
AU2020283048A1 (en) 2019-05-31 2021-12-23 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
EP3976066A4 (en) 2019-05-31 2023-06-28 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
JP7528935B2 (ja) 2019-06-20 2024-08-06 Jsr株式会社 細胞塊群の製造方法および製造装置
KR102213931B1 (ko) * 2019-09-16 2021-02-05 포항공과대학교 산학협력단 줄기세포 또는 종양세포 기반 다종세포 조직 구조 모사체 및 이의 제조 방법
JP7636446B2 (ja) 2020-06-25 2025-02-26 ネクストアンドバイオ インコーポレイテッド ハイドロゲルを用いない幹細胞の大量増殖方法
CN114423858A (zh) * 2020-06-25 2022-04-29 株式会社下一代生物 标准型类器官的生产方法
CN112300933B (zh) * 2020-10-30 2023-10-03 广州迈普再生医学科技股份有限公司 类器官成型装置及方法
KR102746470B1 (ko) 2021-07-09 2024-12-26 주식회사 넥스트앤바이오 가상 오가노이드 생성 방법
CN114908032B (zh) * 2022-03-18 2024-01-09 暨南大学 一种类睾丸器官的制备、培养、冻存复苏方法及应用
WO2023226884A1 (en) * 2022-05-24 2023-11-30 Bioarchitec Group Limited High-throughput selection and fabrication of biomaterial-encapsulated cell mass and uses thereof
CN115261302B (zh) * 2022-07-20 2023-06-06 创芯国际生物科技(广州)有限公司 一种基质胶及其制备方法和应用
CN115537376A (zh) * 2022-10-27 2022-12-30 四川大学华西第二医院 一种睾丸类器官及其构建方法与应用
CN115418386B (zh) * 2022-11-03 2023-03-24 成都诺医德医学检验实验室有限公司 一种基于皮肤类器官的损伤愈合评价方法及模型和应用
GB202306791D0 (en) 2023-05-09 2023-06-21 Cellesce Ltd Apparatus
GB202306769D0 (en) 2023-05-09 2023-06-21 Cellesce Ltd Composition
CN117050934B (zh) * 2023-10-11 2024-01-30 四川大学华西医院 小鼠前列腺类器官制备方法及原发原位前列腺癌动物模型

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937182A (en) 1985-12-19 1990-06-26 Peralta Cancer Research Institute Method for predicting chemosensitivity of anti-cancer drugs
US4816395A (en) 1985-12-19 1989-03-28 Peralta Cancer Research Institute Method for predicting chemosensitivity of anti-cancer drugs
GB0217981D0 (en) 2002-08-02 2002-09-11 Univ Durham Method for preparation, purification and differentiation of neurospheres from mammalian stem cells
US8252591B2 (en) 2004-05-07 2012-08-28 Whitehead Institute For Biomedical Research Hormone responsive tissue culture system and uses thereof
WO2007094511A1 (ja) 2006-02-15 2007-08-23 Oxygenix Co., Ltd. ヘモグロビンベース酸素運搬体を用いた動物細胞の培養方法
WO2009023194A2 (en) 2007-08-10 2009-02-19 Whitehead Institute For Biomedical Research Hormone responsive tissue culture system and uses thereof
CA2824553A1 (en) * 2011-01-19 2012-07-26 The Regents Of The University Of California Somatic cells with innate potential for pluripotency
FR2971255B1 (fr) * 2011-02-04 2015-03-27 Centre Nat Rech Scient Bioreacteur pour la culture cellulaire sur substrat tridimensionnel
US20140178894A1 (en) 2011-04-20 2014-06-26 Novartis Forschungsstiftung, Zweigniederlassung Culture medium suitable for the culture of undifferentiated cells
US20140302491A1 (en) * 2011-10-28 2014-10-09 The Board Of Trustees Of The Leland Stanford Junior University Ex Vivo Culture, Proliferation and Expansion of Primary Tissue Organoids
JP2014233209A (ja) 2013-05-31 2014-12-15 株式会社古河電工アドバンストエンジニアリング 細胞分離方法および細胞分離装置
JP2015062392A (ja) 2013-09-26 2015-04-09 学校法人東京電機大学 毛細血管の製造方法および毛細血管の製造装置
JP6482052B2 (ja) 2014-02-10 2019-03-13 国立大学法人北陸先端科学技術大学院大学 細胞シート及び三次元細胞培養体の凍結保存のための緩慢ガラス化方法
US10597633B2 (en) * 2014-05-16 2020-03-24 Koninklijke Nederlandse Akademie Van Wetenschappen Culture method for organoids
GB201421094D0 (en) 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
GB201421092D0 (en) 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium

Also Published As

Publication number Publication date
PT3481942T (pt) 2022-04-05
EP4056679A1 (en) 2022-09-14
DK3481942T3 (da) 2022-04-11
GB201611982D0 (en) 2016-08-24
US20220333064A1 (en) 2022-10-20
US12351820B2 (en) 2025-07-08
EP3481942B1 (en) 2022-02-16
CN109844097A (zh) 2019-06-04
JP2019521707A (ja) 2019-08-08
ES2910714T3 (es) 2022-05-13
EP3481942A1 (en) 2019-05-15
US20250368952A1 (en) 2025-12-04
CA3028111A1 (en) 2018-01-18
CN117402826A (zh) 2024-01-16
US11401501B2 (en) 2022-08-02
US20190249137A1 (en) 2019-08-15
WO2018011558A1 (en) 2018-01-18
CN109844097B (zh) 2023-10-31
JP7123412B2 (ja) 2022-08-23

Similar Documents

Publication Publication Date Title
PL3481942T3 (pl) Sposoby hodowania organoidów
IL304117A (en) Anti-pvrig antibodies and methods of use
IL285101A (en) Antibodies targeting g-protein coupled receptor and methods of use
IL264758B (en) Methods for flexible resource usage
DK3515600T3 (da) Array af organoider
PL3445850T3 (pl) Sposoby otrzymywania jednoniciowego rna
IL251970B (en) Anti-cd79b antibodies and methods of use
IL251470B (en) Targeted augmentation of nuclear gene output
PL3353210T3 (pl) Przeciwciała anty-TIGIT i sposoby stosowania
PL3215532T3 (pl) Przeciwciała anty-TIM3 i sposoby ich zastosowania
EP3547968A4 (en) PROSTHESIS OBTAINED BY TISSUE ENGINEERING
KR20180084817A (ko) 항-siglec-9 항체 및 이의 이용 방법
DK3292134T3 (da) Metode til dyrkning af akkermansia
EP4212536C0 (en) BENZOXAZEPINE OXAZOLIDINONE COMPOUNDS AND METHODS OF USE
PL3325443T3 (pl) Sposób otrzymywania pridopidyny
PT3548033T (pt) Compostos e respectivos métodos de utilização
PL3250610T3 (pl) Przeciwciała anty-FcRn i sposoby ich stosowania
LT3174394T (lt) Augalo inokuliavimo būdas
IL251505A0 (en) Neuroactive compounds and methods of use thereof
IL272851A (en) Methods of using dipivefrin
EP3152293C0 (en) PERFUSION CULTURE METHODS AND USES THEREOF
LT3271347T (lt) Priešgrybeliniai junginiai ir jų gamybos būdai
LT3490988T (lt) Naujas junginys ir gavimo būdas
LT3237432T (lt) Baltymo gamyba
PL3102503T3 (pl) Kartusz oraz sposób wytwarzania kartusza