PL3481942T3 - Sposoby hodowania organoidów - Google Patents
Sposoby hodowania organoidówInfo
- Publication number
- PL3481942T3 PL3481942T3 PL17742271T PL17742271T PL3481942T3 PL 3481942 T3 PL3481942 T3 PL 3481942T3 PL 17742271 T PL17742271 T PL 17742271T PL 17742271 T PL17742271 T PL 17742271T PL 3481942 T3 PL3481942 T3 PL 3481942T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- growing organoids
- organoids
- growing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
- C12N2509/10—Mechanical dissociation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1611982.8A GB201611982D0 (en) | 2016-07-11 | 2016-07-11 | Cell culture |
| PCT/GB2017/052026 WO2018011558A1 (en) | 2016-07-11 | 2017-07-11 | Methods for culturing organoids |
| EP17742271.4A EP3481942B1 (en) | 2016-07-11 | 2017-07-11 | Methods for culturing organoids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3481942T3 true PL3481942T3 (pl) | 2022-06-20 |
Family
ID=56890801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17742271T PL3481942T3 (pl) | 2016-07-11 | 2017-07-11 | Sposoby hodowania organoidów |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11401501B2 (pl) |
| EP (2) | EP3481942B1 (pl) |
| JP (1) | JP7123412B2 (pl) |
| CN (2) | CN117402826A (pl) |
| CA (1) | CA3028111A1 (pl) |
| DK (1) | DK3481942T3 (pl) |
| ES (1) | ES2910714T3 (pl) |
| GB (1) | GB201611982D0 (pl) |
| PL (1) | PL3481942T3 (pl) |
| PT (1) | PT3481942T (pl) |
| WO (1) | WO2018011558A1 (pl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| AU2015331848B2 (en) | 2014-10-17 | 2022-03-03 | Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
| CN109415685B (zh) | 2016-05-05 | 2023-07-04 | 儿童医院医疗中心 | 用于体外制造胃底组织的方法和与其相关的组合物 |
| EP3534976A4 (en) | 2016-11-04 | 2020-09-16 | Children's Hospital Medical Center | PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE |
| CA3045145A1 (en) | 2016-12-05 | 2018-06-14 | Children's Hospital Medical Center | Colonic organoids and methods of making and using same |
| WO2018191673A1 (en) | 2017-04-14 | 2018-10-18 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| JP2020536529A (ja) | 2017-10-10 | 2020-12-17 | チルドレンズ ホスピタル メディカル センター | 食道組織および/または臓器組成物およびそれを作製する方法 |
| WO2019126626A1 (en) | 2017-12-21 | 2019-06-27 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| EP3826652B1 (en) | 2018-07-26 | 2026-02-25 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| EP3849568A4 (en) | 2018-09-12 | 2022-06-15 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| CN109321528A (zh) * | 2018-09-18 | 2019-02-12 | 梁廷波 | 中国人B7-H5表达阳性胰腺癌细胞系sipanc-1076建立方法 |
| EP3898944A1 (en) * | 2018-12-19 | 2021-10-27 | Regents of the University of Minnesota | Methods for generating and using organoids and tissue therein |
| US20220088085A1 (en) * | 2019-02-28 | 2022-03-24 | Public University Corporation Yokohama City University | Composition for treating blood coagulation and/or complement disorders |
| AU2020283048A1 (en) | 2019-05-31 | 2021-12-23 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| EP3976066A4 (en) | 2019-05-31 | 2023-06-28 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| JP7528935B2 (ja) | 2019-06-20 | 2024-08-06 | Jsr株式会社 | 細胞塊群の製造方法および製造装置 |
| KR102213931B1 (ko) * | 2019-09-16 | 2021-02-05 | 포항공과대학교 산학협력단 | 줄기세포 또는 종양세포 기반 다종세포 조직 구조 모사체 및 이의 제조 방법 |
| JP7636446B2 (ja) | 2020-06-25 | 2025-02-26 | ネクストアンドバイオ インコーポレイテッド | ハイドロゲルを用いない幹細胞の大量増殖方法 |
| CN114423858A (zh) * | 2020-06-25 | 2022-04-29 | 株式会社下一代生物 | 标准型类器官的生产方法 |
| CN112300933B (zh) * | 2020-10-30 | 2023-10-03 | 广州迈普再生医学科技股份有限公司 | 类器官成型装置及方法 |
| KR102746470B1 (ko) | 2021-07-09 | 2024-12-26 | 주식회사 넥스트앤바이오 | 가상 오가노이드 생성 방법 |
| CN114908032B (zh) * | 2022-03-18 | 2024-01-09 | 暨南大学 | 一种类睾丸器官的制备、培养、冻存复苏方法及应用 |
| WO2023226884A1 (en) * | 2022-05-24 | 2023-11-30 | Bioarchitec Group Limited | High-throughput selection and fabrication of biomaterial-encapsulated cell mass and uses thereof |
| CN115261302B (zh) * | 2022-07-20 | 2023-06-06 | 创芯国际生物科技(广州)有限公司 | 一种基质胶及其制备方法和应用 |
| CN115537376A (zh) * | 2022-10-27 | 2022-12-30 | 四川大学华西第二医院 | 一种睾丸类器官及其构建方法与应用 |
| CN115418386B (zh) * | 2022-11-03 | 2023-03-24 | 成都诺医德医学检验实验室有限公司 | 一种基于皮肤类器官的损伤愈合评价方法及模型和应用 |
| GB202306791D0 (en) | 2023-05-09 | 2023-06-21 | Cellesce Ltd | Apparatus |
| GB202306769D0 (en) | 2023-05-09 | 2023-06-21 | Cellesce Ltd | Composition |
| CN117050934B (zh) * | 2023-10-11 | 2024-01-30 | 四川大学华西医院 | 小鼠前列腺类器官制备方法及原发原位前列腺癌动物模型 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937182A (en) | 1985-12-19 | 1990-06-26 | Peralta Cancer Research Institute | Method for predicting chemosensitivity of anti-cancer drugs |
| US4816395A (en) | 1985-12-19 | 1989-03-28 | Peralta Cancer Research Institute | Method for predicting chemosensitivity of anti-cancer drugs |
| GB0217981D0 (en) | 2002-08-02 | 2002-09-11 | Univ Durham | Method for preparation, purification and differentiation of neurospheres from mammalian stem cells |
| US8252591B2 (en) | 2004-05-07 | 2012-08-28 | Whitehead Institute For Biomedical Research | Hormone responsive tissue culture system and uses thereof |
| WO2007094511A1 (ja) | 2006-02-15 | 2007-08-23 | Oxygenix Co., Ltd. | ヘモグロビンベース酸素運搬体を用いた動物細胞の培養方法 |
| WO2009023194A2 (en) | 2007-08-10 | 2009-02-19 | Whitehead Institute For Biomedical Research | Hormone responsive tissue culture system and uses thereof |
| CA2824553A1 (en) * | 2011-01-19 | 2012-07-26 | The Regents Of The University Of California | Somatic cells with innate potential for pluripotency |
| FR2971255B1 (fr) * | 2011-02-04 | 2015-03-27 | Centre Nat Rech Scient | Bioreacteur pour la culture cellulaire sur substrat tridimensionnel |
| US20140178894A1 (en) | 2011-04-20 | 2014-06-26 | Novartis Forschungsstiftung, Zweigniederlassung | Culture medium suitable for the culture of undifferentiated cells |
| US20140302491A1 (en) * | 2011-10-28 | 2014-10-09 | The Board Of Trustees Of The Leland Stanford Junior University | Ex Vivo Culture, Proliferation and Expansion of Primary Tissue Organoids |
| JP2014233209A (ja) | 2013-05-31 | 2014-12-15 | 株式会社古河電工アドバンストエンジニアリング | 細胞分離方法および細胞分離装置 |
| JP2015062392A (ja) | 2013-09-26 | 2015-04-09 | 学校法人東京電機大学 | 毛細血管の製造方法および毛細血管の製造装置 |
| JP6482052B2 (ja) | 2014-02-10 | 2019-03-13 | 国立大学法人北陸先端科学技術大学院大学 | 細胞シート及び三次元細胞培養体の凍結保存のための緩慢ガラス化方法 |
| US10597633B2 (en) * | 2014-05-16 | 2020-03-24 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture method for organoids |
| GB201421094D0 (en) | 2014-11-27 | 2015-01-14 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium |
| GB201421092D0 (en) | 2014-11-27 | 2015-01-14 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium |
-
2016
- 2016-07-11 GB GBGB1611982.8A patent/GB201611982D0/en not_active Ceased
-
2017
- 2017-07-11 WO PCT/GB2017/052026 patent/WO2018011558A1/en not_active Ceased
- 2017-07-11 EP EP17742271.4A patent/EP3481942B1/en active Active
- 2017-07-11 EP EP22156785.2A patent/EP4056679A1/en active Pending
- 2017-07-11 CN CN202311347732.3A patent/CN117402826A/zh active Pending
- 2017-07-11 ES ES17742271T patent/ES2910714T3/es active Active
- 2017-07-11 JP JP2019523191A patent/JP7123412B2/ja active Active
- 2017-07-11 DK DK17742271.4T patent/DK3481942T3/da active
- 2017-07-11 PT PT177422714T patent/PT3481942T/pt unknown
- 2017-07-11 PL PL17742271T patent/PL3481942T3/pl unknown
- 2017-07-11 US US16/316,573 patent/US11401501B2/en active Active
- 2017-07-11 CN CN201780043146.6A patent/CN109844097B/zh active Active
- 2017-07-11 CA CA3028111A patent/CA3028111A1/en active Pending
-
2022
- 2022-07-06 US US17/858,920 patent/US12351820B2/en active Active
-
2025
- 2025-06-12 US US19/236,284 patent/US20250368952A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT3481942T (pt) | 2022-04-05 |
| EP4056679A1 (en) | 2022-09-14 |
| DK3481942T3 (da) | 2022-04-11 |
| GB201611982D0 (en) | 2016-08-24 |
| US20220333064A1 (en) | 2022-10-20 |
| US12351820B2 (en) | 2025-07-08 |
| EP3481942B1 (en) | 2022-02-16 |
| CN109844097A (zh) | 2019-06-04 |
| JP2019521707A (ja) | 2019-08-08 |
| ES2910714T3 (es) | 2022-05-13 |
| EP3481942A1 (en) | 2019-05-15 |
| US20250368952A1 (en) | 2025-12-04 |
| CA3028111A1 (en) | 2018-01-18 |
| CN117402826A (zh) | 2024-01-16 |
| US11401501B2 (en) | 2022-08-02 |
| US20190249137A1 (en) | 2019-08-15 |
| WO2018011558A1 (en) | 2018-01-18 |
| CN109844097B (zh) | 2023-10-31 |
| JP7123412B2 (ja) | 2022-08-23 |
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