DK3515600T3 - Array af organoider - Google Patents

Array af organoider Download PDF

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Publication number
DK3515600T3
DK3515600T3 DK17781009.0T DK17781009T DK3515600T3 DK 3515600 T3 DK3515600 T3 DK 3515600T3 DK 17781009 T DK17781009 T DK 17781009T DK 3515600 T3 DK3515600 T3 DK 3515600T3
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DK
Denmark
Prior art keywords
organoids
array
Prior art date
Application number
DK17781009.0T
Other languages
English (en)
Inventor
Sylke Hoehnel
Nathalie Brandenberg
Matthias Lutolf
Original Assignee
Ecole Polytechnique Fed Lausanne Epfl
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Publication date
Application filed by Ecole Polytechnique Fed Lausanne Epfl filed Critical Ecole Polytechnique Fed Lausanne Epfl
Application granted granted Critical
Publication of DK3515600T3 publication Critical patent/DK3515600T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50857—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0631—Mammary cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
DK17781009.0T 2016-09-19 2017-09-15 Array af organoider DK3515600T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16189510.7A EP3296018A1 (en) 2016-09-19 2016-09-19 Organoid arrays
PCT/EP2017/073357 WO2018050862A1 (en) 2016-09-19 2017-09-15 Organoid arrays

Publications (1)

Publication Number Publication Date
DK3515600T3 true DK3515600T3 (da) 2023-08-07

Family

ID=57103799

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17781009.0T DK3515600T3 (da) 2016-09-19 2017-09-15 Array af organoider

Country Status (7)

Country Link
US (1) US20200010797A1 (da)
EP (2) EP3296018A1 (da)
DK (1) DK3515600T3 (da)
ES (1) ES2952105T3 (da)
HU (1) HUE062571T2 (da)
PT (1) PT3515600T (da)
WO (1) WO2018050862A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
SG11201703493SA (en) 2014-10-29 2017-05-30 Corning Inc Cell culture insert
JP6930914B2 (ja) 2014-10-29 2021-09-01 コーニング インコーポレイテッド 灌流バイオリアクタ・プラットフォーム
JP7245222B2 (ja) 2017-07-14 2023-03-23 コーニング インコーポレイテッド 手動又は自動で培地を交換するための３ｄ細胞培養容器
WO2019014610A1 (en) 2017-07-14 2019-01-17 Corning Incorporated CELL CULTURE CONTAINER FOR 3D CULTURE AND METHODS OF CULTURING 3D CELLS
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
FR3081168B1 (fr) * 2018-05-21 2022-03-11 Univ Bordeaux Systeme de culture cellulaire en bioreacteur
CN108728356B (zh) * 2018-05-23 2022-02-22 北京科技大学 用于不同三维细胞团配对的装置及共培养方法
JP7171695B2 (ja) 2018-07-13 2022-11-15 コーニング インコーポレイテッド 液体培地送達面を含む側壁を有するマイクロキャビティ皿
CN111065725B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 包括具有互联的壁的微板的流体装置
WO2020013845A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Cell culture vessels with stabilizer devices
EP3924468A1 (en) * 2019-02-11 2021-12-22 Miltenyi Biotec B.V. & Co. KG Generation of human pluripotent stem cell derived artificial tissue structures without three dimensional matrices
WO2020234170A1 (en) 2019-05-17 2020-11-26 Medizinische Universität Wien Cell-spheroid production in 2d cell culture system
WO2020242904A1 (en) * 2019-05-30 2020-12-03 Corning Incorporated Cell storage and transportation medium and system and method of transport of cell aggregates
DE102020202529A1 (de) 2020-02-27 2021-09-02 Robert Bosch Gesellschaft mit beschränkter Haftung Verfahren zur Identifikation einer Wirkstoffkombination
US11727586B2 (en) 2020-04-21 2023-08-15 Sartorius Bioanalytical Instruments, Inc. Image processing and segmentation of sets of Z-stacked images of three-dimensional biological samples
CN112680417A (zh) * 2020-12-31 2021-04-20 汪雪 一种卵巢癌类器官培养基及培养方法
EP4029934A1 (en) * 2021-01-18 2022-07-20 Universite De Geneve Methods of producing cell spheroids and tool therefore
WO2023028366A2 (en) * 2021-08-27 2023-03-02 Cell Microsystems, Inc. Automated system for imaging, identification, and isolation of organoids
CN114214282B (zh) * 2021-12-31 2024-04-02 四川大学华西医院 一种培养肺肿瘤类器官的方法
CN114214283B (zh) * 2021-12-31 2024-02-09 四川大学华西医院 一种培养肝肿瘤类器官的方法
CN115433679B (zh) * 2022-06-17 2023-06-09 成都诺医德医学检验实验室有限公司 一种类器官培养装置及制造方法和应用
CN116539862B (zh) * 2022-07-20 2024-03-12 成都诺医德医学检验实验室有限公司 一种基于类器官共生长平台测试肿瘤转移能力的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9303245B2 (en) 2008-06-20 2016-04-05 Universiteit Maastricht Self-assembling tissue modules
US10351819B2 (en) * 2014-09-16 2019-07-16 The Regents Of The University Of California Method for fabrication of microwells for controlled formation of 3-dimensional multicellular-shapes
DK3237597T3 (da) 2014-12-22 2021-03-15 Ecole Polytechnique Fed Lausanne Epfl Indretninger til højgennemløbsaggregering og manipulation af pattedyrsceller
WO2016141137A1 (en) * 2015-03-03 2016-09-09 President And Fellows Of Harvard College Methods of generating functional human tissue

Also Published As

Publication number Publication date
EP3515600B1 (en) 2023-05-10
HUE062571T2 (hu) 2023-11-28
US20200010797A1 (en) 2020-01-09
WO2018050862A1 (en) 2018-03-22
EP3296018A1 (en) 2018-03-21
EP3515600A1 (en) 2019-07-31
ES2952105T3 (es) 2023-10-27
PT3515600T (pt) 2023-08-02

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