PL3453387T3 - Schemat dawkowania dla agonisty receptora s1p - Google Patents

Schemat dawkowania dla agonisty receptora s1p

Info

Publication number
PL3453387T3
PL3453387T3 PL18201062T PL18201062T PL3453387T3 PL 3453387 T3 PL3453387 T3 PL 3453387T3 PL 18201062 T PL18201062 T PL 18201062T PL 18201062 T PL18201062 T PL 18201062T PL 3453387 T3 PL3453387 T3 PL 3453387T3
Authority
PL
Poland
Prior art keywords
receptor agonist
dosing chart
dosing
chart
agonist
Prior art date
Application number
PL18201062T
Other languages
English (en)
Inventor
Robert Schmouder
Thomas Dumortier
Olivier David
Michael Looby
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3453387(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL3453387T3 publication Critical patent/PL3453387T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL18201062T 2008-12-22 2009-12-21 Schemat dawkowania dla agonisty receptora s1p PL3453387T3 (pl)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US13967208P 2008-12-22 2008-12-22
US21853009P 2009-06-19 2009-06-19
US24671509P 2009-09-29 2009-09-29
EP18201062.9A EP3453387B1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist
PCT/US2009/068888 WO2010075239A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist
EP09797234.3A EP2379067B1 (en) 2008-12-22 2009-12-21 Dosage regimen for fingolimod for the treatment of multiple sclerosis
EP16182876.9A EP3120844A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist
EP15158251.7A EP2907511A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist

Publications (1)

Publication Number Publication Date
PL3453387T3 true PL3453387T3 (pl) 2020-11-02

Family

ID=41667217

Family Applications (4)

Application Number Title Priority Date Filing Date
PL09797234T PL2379067T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania fingolimodu w leczeniu stwardnienia rozsianego
PL18179301T PL3409274T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania dla agonisty receptora s1p
PL22187007.4T PL4098256T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania dla agonisty receptora s1p
PL18201062T PL3453387T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania dla agonisty receptora s1p

Family Applications Before (3)

Application Number Title Priority Date Filing Date
PL09797234T PL2379067T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania fingolimodu w leczeniu stwardnienia rozsianego
PL18179301T PL3409274T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania dla agonisty receptora s1p
PL22187007.4T PL4098256T3 (pl) 2008-12-22 2009-12-21 Schemat dawkowania dla agonisty receptora s1p

Country Status (43)

Country Link
US (12) US20100160259A1 (pl)
EP (7) EP3453387B1 (pl)
JP (7) JP2012513401A (pl)
KR (1) KR101347919B1 (pl)
CN (1) CN102264359A (pl)
AR (1) AR074826A1 (pl)
AU (1) AU2009330176C9 (pl)
BR (1) BRPI0923500A2 (pl)
CA (1) CA2747802C (pl)
CL (2) CL2011001529A1 (pl)
CO (1) CO6390117A2 (pl)
CR (1) CR20110274A (pl)
CU (1) CU20110136A7 (pl)
CY (5) CY1116990T1 (pl)
DK (4) DK3409274T3 (pl)
EA (1) EA201100978A1 (pl)
EC (1) ECSP11011222A (pl)
ES (4) ES3017254T3 (pl)
FI (2) FI4098256T3 (pl)
FR (2) FR20C1060I1 (pl)
HN (1) HN2011001759A (pl)
HR (4) HRP20151190T1 (pl)
HU (6) HUE048717T4 (pl)
IL (3) IL213170A0 (pl)
LT (5) LT3453387T (pl)
LU (1) LUC00183I2 (pl)
MA (1) MA32981B1 (pl)
ME (2) ME03802B (pl)
MX (3) MX385959B (pl)
NO (1) NO2020038I1 (pl)
NZ (1) NZ593065A (pl)
PE (1) PE20120337A1 (pl)
PL (4) PL2379067T3 (pl)
PT (4) PT4098256T (pl)
RS (3) RS60666B1 (pl)
SG (1) SG171404A1 (pl)
SI (4) SI3409274T1 (pl)
SM (2) SMT202000441T1 (pl)
TN (1) TN2011000272A1 (pl)
TW (1) TW201028143A (pl)
UY (1) UY32352A (pl)
WO (1) WO2010075239A1 (pl)
ZA (2) ZA201103863B (pl)

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WO2009115954A1 (en) * 2008-03-17 2009-09-24 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
PL2379067T3 (pl) 2008-12-22 2016-02-29 Novartis Ag Schemat dawkowania fingolimodu w leczeniu stwardnienia rozsianego
EP3061449A1 (en) 2009-09-29 2016-08-31 Novartis AG Dosage regimen of an s1p receptor modulator
US20110124605A1 (en) * 2009-11-20 2011-05-26 Shreeram Aradhye Use of an S1P Receptor Agonist
CA2786994C (en) 2010-01-27 2018-01-16 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
AU2011249789B2 (en) * 2010-05-06 2015-03-19 Novartis Ag Dosage regimen of diaryl sulfide derivatives
EP2455080A1 (en) * 2010-11-23 2012-05-23 Almirall, S.A. S1P1 receptor agonists for use in the treatment of multiple sclerosis
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
JP6111202B2 (ja) 2011-01-07 2017-04-05 ノバルティス アーゲー 免疫抑制製剤
US9592288B2 (en) 2011-02-18 2017-03-14 The Scripps Research Institute Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
JO3177B1 (ar) 2011-04-01 2018-03-08 Novartis Ag تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
WO2012162392A1 (en) * 2011-05-23 2012-11-29 Timothy Hla Endothelium protective materials and methods of use
TW201320994A (zh) * 2011-10-11 2013-06-01 Novartis Ag 投藥療程
SMT202000298T1 (it) 2012-08-17 2020-07-08 Actelion Pharmaceuticals Ltd Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo
US20160129084A1 (en) * 2013-03-06 2016-05-12 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure
US10022340B2 (en) 2013-10-11 2018-07-17 Teikoku Pharma Usa, Inc. Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same
US10675254B2 (en) 2013-10-11 2020-06-09 Teikoku Seiyaku Co., Ltd. Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
EP3831378A1 (en) * 2014-04-10 2021-06-09 Novartis AG Siponimod immediate release dosage regimen for treating autoimmune diseases
DK3256125T3 (da) 2014-12-11 2022-03-21 Actelion Pharmaceuticals Ltd Doseringsregimen for ponesimod, en selektiv s1p1-receptoragonist
MA41139B1 (fr) 2014-12-11 2026-02-27 Laboratoires Juvise Pharmaceuticals Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
US20180042895A1 (en) 2015-02-26 2018-02-15 Novartis Ag Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
PL3310760T3 (pl) 2015-06-22 2023-03-06 Arena Pharmaceuticals, Inc. Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1
KR20190116416A (ko) 2017-02-16 2019-10-14 아레나 파마슈티칼스, 인크. 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법
JP2020507610A (ja) 2017-02-16 2020-03-12 アリーナ ファーマシューティカルズ， インコーポレイテッド 腸管外症状を伴う炎症性腸疾患の治療のための化合物および方法
AU2019280822A1 (en) 2018-06-06 2021-01-07 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
TW202131921A (zh) 2019-10-31 2021-09-01 瑞士商愛杜西亞製藥有限公司 Cxcr7拮抗劑與s1p1受體調節劑之組合
WO2021158838A1 (en) 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor modulator
WO2021158848A1 (en) * 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor agonist
EP4110332A4 (en) * 2020-02-28 2024-03-06 Akaal Pharma Pty Ltd S1p receptor modulators
CN113332435B (zh) * 2021-06-18 2022-10-18 广州中医药大学(广州中医药研究院) 鞘氨醇-1-磷酸4受体激动剂及其与真武汤联合在制备治疗慢性肾小球肾炎药物中的应用

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AU8533101A (en) 2000-08-31 2002-03-13 Merck & Co Inc Phosphate derivatives as immunoregulatory agents
CA2483594C (en) 2002-05-16 2011-02-15 Novartis Ag Use of edg receptor binding agents in cancer
US20050090520A1 (en) * 2003-09-12 2005-04-28 Per Lindquist Treatment of disease or injury of the nervous system with FTY720
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SG187468A1 (en) * 2004-11-29 2013-02-28 Novartis Ag Dosage regimen of an s1p receptor agonist
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CN101541227B (zh) * 2005-02-10 2013-06-05 G.I.视频有限公司 用于带导向元件的胃肠工具的前进技术
PT2465492E (pt) * 2007-10-12 2015-10-15 Novartis Ag Composições que compreendem moduladores de receptores de esfingosina-1-fosfato (s1p)
WO2009115954A1 (en) * 2008-03-17 2009-09-24 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
KR20180017232A (ko) * 2008-06-20 2018-02-20 노파르티스 아게 다발성 경화증을 치료하기 위한 소아용 조성물
PL2379067T3 (pl) 2008-12-22 2016-02-29 Novartis Ag Schemat dawkowania fingolimodu w leczeniu stwardnienia rozsianego
WO2010072703A1 (en) 2008-12-22 2010-07-01 Novartis Ag Dosage regimen of an s1p receptor agonist

Also Published As

Publication number Publication date
JP2024129030A (ja) 2024-09-26
PT3409274T (pt) 2019-12-17
US20250262171A1 (en) 2025-08-21
KR20110096175A (ko) 2011-08-29
ZA201205942B (en) 2013-03-27
SMT202000441T1 (it) 2020-09-10
EP4098256A1 (en) 2022-12-07
CY1123255T1 (el) 2021-10-29
ECSP11011222A (es) 2011-08-31
CY2020036I2 (el) 2021-06-25
SI2379067T1 (sl) 2016-01-29
PE20120337A1 (es) 2012-04-24
HRP20151190T1 (hr) 2016-01-01
TN2011000272A1 (en) 2012-12-17
CU20110136A7 (es) 2012-01-31
SI3453387T1 (sl) 2020-10-30
ES2810823T3 (es) 2021-03-09
CL2011001529A1 (es) 2012-02-24
WO2010075239A1 (en) 2010-07-01
NZ593065A (en) 2012-11-30
BRPI0923500A2 (pt) 2018-05-29
CR20110274A (es) 2011-07-19
EP4098256B1 (en) 2025-02-26
CN102264359A (zh) 2011-11-30
FR20C1060I1 (fr) 2020-12-25
EP3409274A1 (en) 2018-12-05
DK3409274T3 (da) 2019-12-16
FIC20253002I1 (fi) 2025-05-23
CA2747802A1 (en) 2010-07-01
SG171404A1 (en) 2011-07-28
US20100160259A1 (en) 2010-06-24
EP3453387A1 (en) 2019-03-13
EP2907511A1 (en) 2015-08-19
FR25C1012I1 (fr) 2025-06-13
EA201100978A1 (ru) 2012-01-30
JP2017141238A (ja) 2017-08-17
HRP20192175T1 (hr) 2020-03-20
HUE026869T2 (en) 2016-08-29
ZA201103863B (en) 2012-10-31
CO6390117A2 (es) 2012-02-29
LT3409274T (lt) 2020-02-10
US20220142949A1 (en) 2022-05-12
US20140148415A1 (en) 2014-05-29
ES3017254T3 (en) 2025-05-12
JP2019167360A (ja) 2019-10-03
CY1122812T1 (el) 2021-05-05
RS60666B1 (sr) 2020-09-30
JP2016135752A (ja) 2016-07-28
CL2013001558A1 (es) 2013-10-25
SMT202000054T1 (it) 2020-03-13
US20200330407A1 (en) 2020-10-22
LT4098256T (lt) 2025-06-10
EP2379067B1 (en) 2015-09-02
US20160081949A1 (en) 2016-03-24
MA32981B1 (fr) 2012-01-02
PL3409274T3 (pl) 2020-06-01
AU2009330176C9 (en) 2017-01-05
PT4098256T (pt) 2025-04-10
DK2379067T3 (en) 2015-12-07
CY1116990T1 (el) 2017-04-05
CY2020036I1 (el) 2021-03-12
AU2009330176B2 (en) 2014-03-06
HUE048717T2 (hu) 2020-08-28
ES2552823T3 (es) 2015-12-02
AR074826A1 (es) 2011-02-16
MX385959B (es) 2025-03-18
ME03594B (me) 2020-07-20
JP2022103194A (ja) 2022-07-07
MX2021010759A (es) 2022-07-19
IL274756A (en) 2020-07-30
SI4098256T1 (sl) 2025-06-30
EP3677260A1 (en) 2020-07-08
ES2760607T3 (es) 2020-05-14
IL278914A (en) 2021-01-31
JP7329965B2 (ja) 2023-08-21
LTPA2025520I1 (pl) 2025-06-25
HUE048717T4 (hu) 2022-02-28
DK4098256T5 (da) 2025-07-21
DK3453387T3 (da) 2020-08-10
DK4098256T3 (da) 2025-04-22
HRP20250568T1 (hr) 2025-07-04
PL2379067T3 (pl) 2016-02-29
AU2009330176A1 (en) 2011-07-07
RS59857B1 (sr) 2020-02-28
HRP20201167T1 (hr) 2020-12-11
CY2025012I1 (el) 2026-02-25
HN2011001759A (es) 2013-11-26
HUE052048T2 (hu) 2021-04-28
EP4098256B9 (en) 2025-06-18
PT2379067E (pt) 2015-12-23
PL4098256T3 (pl) 2025-06-09
US20180289638A1 (en) 2018-10-11
TW201028143A (en) 2010-08-01
MX2011006623A (es) 2011-07-12
RS66784B9 (sr) 2025-08-29
EP3120844A1 (en) 2017-01-25
IL213170A0 (en) 2011-07-31
KR101347919B1 (ko) 2014-01-07
EP3453387B1 (en) 2020-06-03
JP2012513401A (ja) 2012-06-14
LT3453387T (lt) 2020-08-25
JP2014144970A (ja) 2014-08-14
HUE071189T2 (hu) 2025-08-28
US20140066657A1 (en) 2014-03-06
ME03802B (me) 2021-04-20
PT3453387T (pt) 2020-08-11
RS66784B1 (sr) 2025-06-30
HUS2000046I1 (hu) 2020-12-28
US20170189353A1 (en) 2017-07-06
EP2379067A1 (en) 2011-10-26
UY32352A (es) 2010-07-30
LTPA2020005I1 (lt) 2020-12-10
LUC00183I2 (pl) 2024-07-01
SI3409274T1 (sl) 2020-03-31
US20110257133A1 (en) 2011-10-20
NO2020038I1 (no) 2020-11-18
CY2025012I2 (el) 2026-02-25
AU2009330176C1 (en) 2016-12-08
US20190091180A1 (en) 2019-03-28
FI4098256T3 (fi) 2025-03-31
EP3409274B1 (en) 2019-11-20
CA2747802C (en) 2021-02-09
US20160263061A1 (en) 2016-09-15
HUS2500026I1 (hu) 2025-07-28

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