CY1122812T1 - Δοσολογικο σχημα για εναν αγωνιστη του υποδοχεα s1p - Google Patents

Δοσολογικο σχημα για εναν αγωνιστη του υποδοχεα s1p

Info

Publication number
CY1122812T1
CY1122812T1 CY20191101264T CY191101264T CY1122812T1 CY 1122812 T1 CY1122812 T1 CY 1122812T1 CY 20191101264 T CY20191101264 T CY 20191101264T CY 191101264 T CY191101264 T CY 191101264T CY 1122812 T1 CY1122812 T1 CY 1122812T1
Authority
CY
Cyprus
Prior art keywords
dosage forms
receptor agent
daily dosage
dosage
receptor
Prior art date
Application number
CY20191101264T
Other languages
English (en)
Inventor
Thomas Dumortier
Olivier David
Michael Looby
Robert Schmouder
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1122812(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1122812T1 publication Critical patent/CY1122812T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Οι ρυθμιστές ή οι αγωνιστές του υποδοχέα S1P χορηγούνται μετά από δοσολογικό σχήμα, κατά το οποίο κατά τη διάρκεια των αρχικών ημερών θεραπείας η ημερήσια δοσολογία είναι χαμηλότερη από την πρότυπη ημερήσια δοσολογία.
CY20191101264T 2008-12-22 2019-12-03 Δοσολογικο σχημα για εναν αγωνιστη του υποδοχεα s1p CY1122812T1 (el)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13967208P 2008-12-22 2008-12-22
US21853009P 2009-06-19 2009-06-19
US24671509P 2009-09-29 2009-09-29
PCT/US2009/068888 WO2010075239A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist
EP15158251.7A EP2907511A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist
EP16182876.9A EP3120844A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist
EP09797234.3A EP2379067B1 (en) 2008-12-22 2009-12-21 Dosage regimen for fingolimod for the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
CY1122812T1 true CY1122812T1 (el) 2021-05-05

Family

ID=41667217

Family Applications (4)

Application Number Title Priority Date Filing Date
CY20151101084T CY1116990T1 (el) 2008-12-22 2015-11-30 Σχημα δοσολογιας για φινγκολιμοδη για την αγωγη σκληρυνσης κατα πλακας
CY20191101264T CY1122812T1 (el) 2008-12-22 2019-12-03 Δοσολογικο σχημα για εναν αγωνιστη του υποδοχεα s1p
CY20201100712T CY1123255T1 (el) 2008-12-22 2020-08-03 Σχημα δοσολογιας για εναν αγωνιστη υποδοχεα s1p
CY2020036C CY2020036I2 (el) 2008-12-22 2020-11-19 Δοσολογικο σχημα για εναν αγωνιστη του υποδοχεα s1p

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20151101084T CY1116990T1 (el) 2008-12-22 2015-11-30 Σχημα δοσολογιας για φινγκολιμοδη για την αγωγη σκληρυνσης κατα πλακας

Family Applications After (2)

Application Number Title Priority Date Filing Date
CY20201100712T CY1123255T1 (el) 2008-12-22 2020-08-03 Σχημα δοσολογιας για εναν αγωνιστη υποδοχεα s1p
CY2020036C CY2020036I2 (el) 2008-12-22 2020-11-19 Δοσολογικο σχημα για εναν αγωνιστη του υποδοχεα s1p

Country Status (40)

Country Link
US (11) US20110257133A1 (el)
EP (7) EP3409274B1 (el)
JP (6) JP2012513401A (el)
KR (1) KR101347919B1 (el)
CN (1) CN102264359A (el)
AR (1) AR074826A1 (el)
AU (1) AU2009330176C9 (el)
BR (1) BRPI0923500A2 (el)
CA (1) CA2747802C (el)
CL (2) CL2011001529A1 (el)
CO (1) CO6390117A2 (el)
CR (1) CR20110274A (el)
CU (1) CU20110136A7 (el)
CY (4) CY1116990T1 (el)
DK (3) DK3453387T3 (el)
EA (1) EA201100978A1 (el)
EC (1) ECSP11011222A (el)
ES (3) ES2552823T3 (el)
FR (1) FR20C1060I1 (el)
HN (1) HN2011001759A (el)
HR (3) HRP20151190T1 (el)
HU (4) HUE048717T4 (el)
IL (3) IL213170A0 (el)
LT (3) LT3453387T (el)
MA (1) MA32981B1 (el)
ME (2) ME03802B (el)
MX (2) MX2011006623A (el)
NO (1) NO2020038I1 (el)
NZ (1) NZ593065A (el)
PE (1) PE20120337A1 (el)
PL (3) PL3409274T3 (el)
PT (3) PT3409274T (el)
RS (2) RS60666B1 (el)
SG (1) SG171404A1 (el)
SI (3) SI2379067T1 (el)
TN (1) TN2011000272A1 (el)
TW (1) TW201028143A (el)
UY (1) UY32352A (el)
WO (1) WO2010075239A1 (el)
ZA (2) ZA201103863B (el)

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DK3453387T3 (da) 2008-12-22 2020-08-10 Novartis Ag Doseringsplan til en s1p-receptoragonist
AU2010300919A1 (en) 2009-09-29 2012-03-22 Novartis Ag Dosage regimen of an S1P receptor modulator
US20110124605A1 (en) * 2009-11-20 2011-05-26 Shreeram Aradhye Use of an S1P Receptor Agonist
SG10201906876PA (en) 2010-01-27 2019-09-27 Arena Pharm Inc Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
KR20130098885A (ko) * 2010-05-06 2013-09-05 노파르티스 아게 디아릴 술피드 유도체의 투여 요법
EP2455080A1 (en) * 2010-11-23 2012-05-23 Almirall, S.A. S1P1 receptor agonists for use in the treatment of multiple sclerosis
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
US9592288B2 (en) 2011-02-18 2017-03-14 The Scripps Research Institute Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
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WO2012162392A1 (en) * 2011-05-23 2012-11-29 Timothy Hla Endothelium protective materials and methods of use
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JP6542678B2 (ja) * 2013-03-06 2019-07-10 アコーダ セラピューティクス インコーポレイテッド 心不全の治療または予防のためのニューレグリンまたはその断片の治療的投与の方法
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CA2943598C (en) * 2014-04-10 2023-03-07 Novartis Ag S1p modulator immediate release dosage regimen
PL3256125T3 (pl) 2014-12-11 2022-05-09 Actelion Pharmaceuticals Ltd Schemat dawkowania ponesimodu, selektywnego agonisty receptora s1p1
CN116850181A (zh) * 2015-01-06 2023-10-10 艾尼纳制药公司 治疗与s1p1受体有关的病症的方法
WO2016135644A1 (en) 2015-02-26 2016-09-01 Novartis Ag Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
ES2929526T3 (es) 2015-06-22 2022-11-29 Arena Pharm Inc Sal cristalina de L-arginina del ácido (R)-2-(7-(4-ciclopentil-3-(trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclo-penta[b]indol-3-il)acético para su uso en trastornos asociados al receptor S1P1
MA47504A (fr) 2017-02-16 2019-12-25 Arena Pharm Inc Composés et méthodes de traitement de l'angiocholite biliaire primitive
CA3053416A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
CA3156298A1 (en) 2019-10-31 2021-05-06 Laetitia POUZOL Combination of a cxcr7 antagonist with an s1p1 receptor modulator
WO2021158848A1 (en) * 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor agonist
US11135197B2 (en) 2020-02-07 2021-10-05 Argentum Pharmaceuticals Llc Dosage regimen of an S1P receptor modulator
CN113332435B (zh) * 2021-06-18 2022-10-18 广州中医药大学(广州中医药研究院) 鞘氨醇-1-磷酸4受体激动剂及其与真武汤联合在制备治疗慢性肾小球肾炎药物中的应用

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PT2278960T (pt) * 2008-03-17 2017-03-09 Actelion Pharmaceuticals Ltd Regime de dosagem para um agonista seletivo do recetor s1p1
EP3011958A1 (en) * 2008-06-20 2016-04-27 Novartis AG Paediatric compositions for treating multiple sclerosis
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PT2379069E (pt) 2008-12-22 2015-07-03 Novartis Ag Inalador

Also Published As

Publication number Publication date
ECSP11011222A (es) 2011-08-31
EP3677260A1 (en) 2020-07-08
US20160081949A1 (en) 2016-03-24
JP2014144970A (ja) 2014-08-14
JP7329965B2 (ja) 2023-08-21
UY32352A (es) 2010-07-30
LTPA2020005I1 (lt) 2020-12-10
CA2747802A1 (en) 2010-07-01
EP3409274B1 (en) 2019-11-20
US20140066657A1 (en) 2014-03-06
ME03594B (me) 2020-07-20
JP2012513401A (ja) 2012-06-14
NZ593065A (en) 2012-11-30
EP2379067B1 (en) 2015-09-02
DK3453387T3 (da) 2020-08-10
US20220142949A1 (en) 2022-05-12
CL2013001558A1 (es) 2013-10-25
CN102264359A (zh) 2011-11-30
ES2760607T3 (es) 2020-05-14
CU20110136A7 (es) 2012-01-31
US20180289638A1 (en) 2018-10-11
TW201028143A (en) 2010-08-01
PL2379067T3 (pl) 2016-02-29
HRP20192175T1 (hr) 2020-03-20
EP2907511A1 (en) 2015-08-19
CY2020036I2 (el) 2021-06-25
IL274756A (en) 2020-07-30
IL278914A (en) 2021-01-31
ES2552823T3 (es) 2015-12-02
AU2009330176C1 (en) 2016-12-08
SG171404A1 (en) 2011-07-28
RS59857B1 (sr) 2020-02-28
US20170189353A1 (en) 2017-07-06
EP3453387B1 (en) 2020-06-03
CY2020036I1 (el) 2021-03-12
JP2016135752A (ja) 2016-07-28
CR20110274A (es) 2011-07-19
KR101347919B1 (ko) 2014-01-07
HRP20201167T1 (hr) 2020-12-11
FR20C1060I1 (fr) 2020-12-25
HUE048717T4 (hu) 2022-02-28
EP3120844A1 (en) 2017-01-25
HUS2000046I1 (hu) 2020-12-28
US20100160259A1 (en) 2010-06-24
JP2017141238A (ja) 2017-08-17
PL3453387T3 (pl) 2020-11-02
ZA201103863B (en) 2012-10-31
SI2379067T1 (sl) 2016-01-29
CO6390117A2 (es) 2012-02-29
LT3409274T (lt) 2020-02-10
TN2011000272A1 (en) 2012-12-17
PL3409274T3 (pl) 2020-06-01
CY1123255T1 (el) 2021-10-29
DK2379067T3 (en) 2015-12-07
IL213170A0 (en) 2011-07-31
AU2009330176C9 (en) 2017-01-05
US20190091180A1 (en) 2019-03-28
HUE048717T2 (hu) 2020-08-28
US20160263061A1 (en) 2016-09-15
CA2747802C (en) 2021-02-09
RS60666B1 (sr) 2020-09-30
EP3453387A1 (en) 2019-03-13
US20110257133A1 (en) 2011-10-20
KR20110096175A (ko) 2011-08-29
AR074826A1 (es) 2011-02-16
PT3409274T (pt) 2019-12-17
EP2379067A1 (en) 2011-10-26
EP3409274A1 (en) 2018-12-05
JP2022103194A (ja) 2022-07-07
LT3453387T (lt) 2020-08-25
HUE052048T2 (hu) 2021-04-28
MX2011006623A (es) 2011-07-12
MA32981B1 (fr) 2012-01-02
PT2379067E (pt) 2015-12-23
US20140148415A1 (en) 2014-05-29
JP2019167360A (ja) 2019-10-03
SI3453387T1 (sl) 2020-10-30
HN2011001759A (es) 2013-11-26
WO2010075239A1 (en) 2010-07-01
AU2009330176A1 (en) 2011-07-07
BRPI0923500A2 (pt) 2018-05-29
CY1116990T1 (el) 2017-04-05
PT3453387T (pt) 2020-08-11
EP4098256A1 (en) 2022-12-07
CL2011001529A1 (es) 2012-02-24
DK3409274T3 (da) 2019-12-16
HUE026869T2 (en) 2016-08-29
US20200330407A1 (en) 2020-10-22
NO2020038I1 (no) 2020-11-18
HRP20151190T1 (hr) 2016-01-01
MX2021010759A (es) 2022-07-19
ZA201205942B (en) 2013-03-27
ME03802B (me) 2021-04-20
PE20120337A1 (es) 2012-04-24
ES2810823T3 (es) 2021-03-09
EA201100978A1 (ru) 2012-01-30
SI3409274T1 (sl) 2020-03-31
AU2009330176B2 (en) 2014-03-06

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