PL3443979T3 - Schemat dawkowania il-2 do leczenia tocznia rumieniowatego układowego - Google Patents

Schemat dawkowania il-2 do leczenia tocznia rumieniowatego układowego

Info

Publication number
PL3443979T3
PL3443979T3 PL18179669T PL18179669T PL3443979T3 PL 3443979 T3 PL3443979 T3 PL 3443979T3 PL 18179669 T PL18179669 T PL 18179669T PL 18179669 T PL18179669 T PL 18179669T PL 3443979 T3 PL3443979 T3 PL 3443979T3
Authority
PL
Poland
Prior art keywords
lupus erythematosus
systemic lupus
dosage regimen
treating systemic
treating
Prior art date
Application number
PL18179669T
Other languages
English (en)
Inventor
David Klatzmann
David SAADOUN
Patrice CACOUB
Michèle ROSENZWAJG
Eliane Piaggio
Gilbert BENSIMON
Claude Bernard
Original Assignee
Assistance Publique - Hôpitaux De Paris
Sorbonne Université
INSERM (Institut National de la Santé et de la Recherche Médicale)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44244599&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3443979(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Assistance Publique - Hôpitaux De Paris, Sorbonne Université, INSERM (Institut National de la Santé et de la Recherche Médicale) filed Critical Assistance Publique - Hôpitaux De Paris
Publication of PL3443979T3 publication Critical patent/PL3443979T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL18179669T 2011-03-11 2012-03-09 Schemat dawkowania il-2 do leczenia tocznia rumieniowatego układowego PL3443979T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161451663P 2011-03-11 2011-03-11
EP11305269 2011-03-11
PCT/EP2012/054174 WO2012123381A1 (en) 2011-03-11 2012-03-09 Use of low dose il-2 for treating autoimmune - related or inflammatory disorders
EP12708029.9A EP2683395B2 (en) 2011-03-11 2012-03-09 USE OF LOW-DOSE IL-2 FOR THE TREATMENT OF TYPE 1 DIABETIC DISORDERS
EP18179669.9A EP3443979B2 (en) 2011-03-11 2012-03-09 IL-2 DOSAGE REGIMEN FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS

Publications (1)

Publication Number Publication Date
PL3443979T3 true PL3443979T3 (pl) 2020-11-16

Family

ID=44244599

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12708029T PL2683395T3 (pl) 2011-03-11 2012-03-09 Zastosowanie małych dawek il-2 do leczenia cukrzycy typu 1
PL18179669T PL3443979T3 (pl) 2011-03-11 2012-03-09 Schemat dawkowania il-2 do leczenia tocznia rumieniowatego układowego

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL12708029T PL2683395T3 (pl) 2011-03-11 2012-03-09 Zastosowanie małych dawek il-2 do leczenia cukrzycy typu 1

Country Status (11)

Country Link
US (1) US12491232B2 (pl)
EP (3) EP3443979B2 (pl)
JP (2) JP6054889B2 (pl)
KR (1) KR102220006B1 (pl)
CN (2) CN103732241A (pl)
AU (4) AU2012228418B2 (pl)
DK (2) DK2683395T3 (pl)
ES (1) ES2693645T3 (pl)
MX (2) MX347324B (pl)
PL (2) PL2683395T3 (pl)
WO (1) WO2012123381A1 (pl)

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EP2943253B1 (en) * 2013-01-09 2021-10-20 University Of Miami Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein and il-2
EP3013355B1 (en) * 2013-06-25 2019-08-07 ICM - Institut du Cerveau et da la Moelle Epinière Il-2 for use in treating alzheimer disease and related disorders
PT3102595T (pt) 2014-02-06 2019-01-11 Hoffmann La Roche Proteínas de fusão de interleucina-2 e suas utilizações
EP2918285A1 (en) * 2014-03-11 2015-09-16 Université Pierre et Marie Curie (Paris 6) Interleukin-2 for treating food allergy
EP3134132B1 (en) * 2014-04-22 2019-07-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the diagnostic of an autoimmune disease
CN104189892A (zh) * 2014-08-22 2014-12-10 北京大学人民医院 低剂量白细胞介素2在免疫相关性疾病治疗中的应用
AU2015328163B2 (en) * 2014-10-09 2020-10-15 Dana-Farber Cancer Institute, Inc. Multiple-variable IL-2 dose regimen for treating immune disorders
CN104459129A (zh) * 2015-01-05 2015-03-25 复旦大学附属华山医院 一种鉴别活动性与潜伏性结核分枝杆菌感染的诊断试剂盒
IL304950A (en) 2015-04-10 2023-10-01 Amgen Inc Interleukin for the expansion of myotonic control T-2 cells
WO2016205714A1 (en) * 2015-06-19 2016-12-22 University Of Louisville Research Foundation, Inc. Immunomodulation for the long term prevention and treatment of autoimmune diseases and foreign tissue rejection
EP3347036A1 (en) * 2015-09-10 2018-07-18 Assistance Publique - Hôpitaux de Paris Use of interleukin 2 for treating spondyloarthritis
EP3402812B2 (en) * 2016-01-11 2026-06-24 Dignity Health Modulators of zinc activated cation channel
US10898576B2 (en) * 2016-03-16 2021-01-26 Yanhui Xie Glucocorticoid combined with polyethylene glycol-modified interleukin 2 for treating respiratory disease
BR112019018915A2 (pt) 2017-03-15 2020-04-14 Pandion Therapeutics Inc imunotolerância direcionada
AU2018273914A1 (en) 2017-05-24 2019-11-14 Pandion Operations, Inc. Targeted immunotolerance
US11618884B2 (en) * 2017-11-14 2023-04-04 Inserm (Institut National De La Sante Et De La Recherche Medicale) Regulatory T cells genetically modified for the lymphotoxin alpha gene and uses thereof
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
USRE50550E1 (en) 2017-12-06 2025-08-26 Pandion Operations, Inc. IL-2 muteins and uses thereof
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
EP3752178A1 (en) * 2018-02-16 2020-12-23 Iltoo Pharma Use of interleukin 2 for treating sjögren's syndrome
EP3796940A1 (en) * 2018-05-21 2021-03-31 Nektar Therapeutics Selective treg stimulator rur20kd-il-2 and related compositions
WO2020007937A1 (en) * 2018-07-03 2020-01-09 Iltoo Pharma Use of interleukin-2 for treating systemic sclerosis
EP3934680A4 (en) * 2019-03-08 2022-12-07 Cend Therapeutics, Inc. LOW-DOSE CYTOKINE ADMINISTRATED WITH ANYTHING FOR THE TREATMENT OF CANCER
CN109999179A (zh) * 2019-05-08 2019-07-12 山东省分析测试中心 低剂量白介素2用于制备治疗阿尔茨海默病药物中的应用
AU2020279240A1 (en) 2019-05-20 2021-12-23 Pandion Operations, Inc. MAdCAM targeted immunotolerance
CN110251659A (zh) * 2019-07-03 2019-09-20 安徽省立医院 一种小剂量白细胞介素2在制备治疗慢性痛风药物中的应用
PH12022550165A1 (en) 2019-07-26 2023-05-08 Visterra Inc Interleukin-2 agents and uses thereof
CN114555634B (zh) 2019-08-13 2025-01-10 美国安进公司 用于扩增调节性t细胞的白介素-2突变蛋白
US11981715B2 (en) 2020-02-21 2024-05-14 Pandion Operations, Inc. Tissue targeted immunotolerance with a CD39 effector
US20230090069A1 (en) 2020-03-06 2023-03-23 Centre Hospitalier Universitaire De Nimes Low dose human interleukin-2 for the treatment of amyotrophic lateral sclerosis
CA3203977A1 (en) 2020-12-04 2022-06-09 Visterra, Inc. Methods of using interleukin-2 agents
CA3211627A1 (en) * 2021-03-11 2022-09-15 Stanley Hersh Appel Methods and compositions for treatment of disease
CN113304248B (zh) * 2021-07-01 2023-01-03 北京大学人民医院 Il-2在制备缓解糖皮质激素类药物副作用的药物中的应用
TW202333772A (zh) 2021-12-01 2023-09-01 美商威特拉公司 使用介白素-2藥劑之方法
CN115607653B (zh) * 2022-07-09 2023-09-26 曹霞 低剂量白介素2在治疗孤独症中的应用
CN115487292B (zh) * 2022-09-28 2025-01-21 河北师范大学 一种治疗糖尿病的联合用药物及其应用
WO2024121173A1 (en) 2022-12-05 2024-06-13 Centre Hospitalier Universitaire De Nimes Low dose human interleukin-2 for the treatment of amyotrophic lateral sclerosis in a subgroup of patients
CN115779072B (zh) * 2023-02-06 2023-10-17 北京大学第三医院（北京大学第三临床医学院） 一种包含低浓度il-2的用于治疗干眼的药物组合物

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Also Published As

Publication number Publication date
DK3443979T3 (da) 2020-08-24
CN109432407A (zh) 2019-03-08
WO2012123381A1 (en) 2012-09-20
AU2018206705B2 (en) 2020-03-19
EP2683395B2 (en) 2026-05-20
MX384095B (es) 2025-03-14
AU2016273847B2 (en) 2018-04-19
KR20140053869A (ko) 2014-05-08
EP3443979B2 (en) 2026-05-20
PL2683395T3 (pl) 2019-04-30
US12491232B2 (en) 2025-12-09
EP2683395B1 (en) 2018-08-01
JP7561893B2 (ja) 2024-10-04
JP6054889B2 (ja) 2016-12-27
AU2012228418A1 (en) 2013-09-05
EP3443979B1 (en) 2020-05-27
MX347324B (es) 2017-04-19
ES2693645T3 (es) 2018-12-13
AU2018206705A1 (en) 2018-08-02
DK2683395T3 (en) 2018-11-19
JP2023029565A (ja) 2023-03-03
US20230149512A1 (en) 2023-05-18
JP2014510725A (ja) 2014-05-01
EP3443979A1 (en) 2019-02-20
CA2828657A1 (en) 2012-09-20
KR102220006B1 (ko) 2021-02-24
MX2013010342A (es) 2014-03-05
AU2020204023A1 (en) 2020-07-09
CN103732241A (zh) 2014-04-16
EP2683395A1 (en) 2014-01-15
AU2016273847A1 (en) 2017-01-05
AU2012228418B2 (en) 2016-09-29
AU2016273847A2 (en) 2017-02-02
EP3766513A1 (en) 2021-01-20
AU2020204023B2 (en) 2022-06-02

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