PL343542A1 - Method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) guanidine monomesilate, method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) quanidine monomesilate, method of obtaining methyl ester of 5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carboxylic acid and method of obtaining methyl 3-cyclopropyl-2-dimethylamino-3-oxopropionate - Google Patents

Method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) guanidine monomesilate, method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) quanidine monomesilate, method of obtaining methyl ester of 5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carboxylic acid and method of obtaining methyl 3-cyclopropyl-2-dimethylamino-3-oxopropionate

Info

Publication number
PL343542A1
PL343542A1 PL00343542A PL34354200A PL343542A1 PL 343542 A1 PL343542 A1 PL 343542A1 PL 00343542 A PL00343542 A PL 00343542A PL 34354200 A PL34354200 A PL 34354200A PL 343542 A1 PL343542 A1 PL 343542A1
Authority
PL
Poland
Prior art keywords
cyclopropyl
obtaining
quinolin
pyrazol
monomesilate
Prior art date
Application number
PL00343542A
Other languages
English (en)
Inventor
Norma Jacqueline Tom
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PL343542A1 publication Critical patent/PL343542A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL00343542A 1999-10-29 2000-10-27 Method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) guanidine monomesilate, method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) quanidine monomesilate, method of obtaining methyl ester of 5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carboxylic acid and method of obtaining methyl 3-cyclopropyl-2-dimethylamino-3-oxopropionate PL343542A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16237799P 1999-10-29 1999-10-29

Publications (1)

Publication Number Publication Date
PL343542A1 true PL343542A1 (en) 2001-05-07

Family

ID=22585372

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00343542A PL343542A1 (en) 1999-10-29 2000-10-27 Method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) guanidine monomesilate, method of obtaining n-(5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carbonyl) quanidine monomesilate, method of obtaining methyl ester of 5-cyclopropyl-1-quinolin-5-yl-1h-pyrazol-4-carboxylic acid and method of obtaining methyl 3-cyclopropyl-2-dimethylamino-3-oxopropionate

Country Status (19)

Country Link
US (1) US6441176B1 (enExample)
EP (1) EP1101763A3 (enExample)
JP (1) JP3342475B2 (enExample)
KR (2) KR100449595B1 (enExample)
CN (1) CN1146557C (enExample)
AR (1) AR029188A1 (enExample)
AU (1) AU779106B2 (enExample)
BR (1) BR0005122A (enExample)
CA (1) CA2324640A1 (enExample)
CZ (1) CZ20004018A3 (enExample)
HU (1) HUP0004187A2 (enExample)
ID (1) ID27904A (enExample)
IL (1) IL139198A0 (enExample)
PL (1) PL343542A1 (enExample)
RU (1) RU2190605C2 (enExample)
TR (1) TR200003143A2 (enExample)
TW (1) TWI221152B (enExample)
YU (1) YU62900A (enExample)
ZA (1) ZA200006007B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852733B2 (en) 2000-04-28 2005-02-08 Pfizer Inc. Sodium-hydrogen exchanger type 1 inhibitor
CA2436539A1 (en) * 2001-01-31 2002-08-08 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
MXPA04004685A (es) * 2001-12-19 2004-08-12 Pfizer Prod Inc Procedimientos para preparar inhibidores de tipo-1 de intercambiador sodio-hidrogeno.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028381A (en) * 1975-05-05 1977-06-07 Ciba-Geigy Corporation Pyrazolobenzazepines
DE4226649A1 (de) * 1992-08-12 1994-02-17 Bayer Ag Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole
RU2009129C1 (ru) * 1991-12-16 1994-03-15 Центр по химии лекарственных средств Арилгидразоны 5,6,7,8-тетрагидрохинолиндионы-2,5, обладающие кардиотонической активностью
US6184380B1 (en) * 1999-01-25 2001-02-06 Pfizer Inc. Process for preparing naphthyridones and intermediates
JP2002504546A (ja) 1998-02-27 2002-02-12 ファイザー・プロダクツ・インク 虚血の治療のためのｎ−［（置換５員ジもしくはトリアザ二不飽和環）カルボニル］グアニジン誘導体
UA72002C2 (en) 1999-10-29 2005-01-17 Pfizer Prod Inc Inhibitors crystals of sodium-hydrogen exchange of 1 type, a method for the preparation thereof (variants), a pharmaceuticalcomposition based thereon and a method for the reduction of tissue damage

Also Published As

Publication number Publication date
YU62900A (sh) 2003-08-29
KR100449595B1 (ko) 2004-09-21
CA2324640A1 (en) 2001-04-29
AR029188A1 (es) 2003-06-18
TR200003143A2 (tr) 2001-05-21
JP3342475B2 (ja) 2002-11-11
CN1146557C (zh) 2004-04-21
US6441176B1 (en) 2002-08-27
KR20010060211A (ko) 2001-07-06
IL139198A0 (en) 2001-11-25
RU2190605C2 (ru) 2002-10-10
CZ20004018A3 (cs) 2002-04-17
ID27904A (id) 2001-05-03
TWI221152B (en) 2004-09-21
JP2001158784A (ja) 2001-06-12
BR0005122A (pt) 2001-06-19
HK1036057A1 (en) 2003-07-10
CN1295070A (zh) 2001-05-16
ZA200006007B (en) 2002-04-26
EP1101763A3 (en) 2002-04-24
EP1101763A2 (en) 2001-05-23
HUP0004187A2 (hu) 2002-11-28
AU6133300A (en) 2001-05-03
AU779106B2 (en) 2005-01-06
KR20030061767A (ko) 2003-07-22
KR100443851B1 (ko) 2004-08-11
HU0004187D0 (enExample) 2001-01-29

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