PL3273942T3 - Plaster mikroigłowy do dostarczania składnika aktywnego do skóry - Google Patents

Plaster mikroigłowy do dostarczania składnika aktywnego do skóry

Info

Publication number
PL3273942T3
PL3273942T3 PL16720351T PL16720351T PL3273942T3 PL 3273942 T3 PL3273942 T3 PL 3273942T3 PL 16720351 T PL16720351 T PL 16720351T PL 16720351 T PL16720351 T PL 16720351T PL 3273942 T3 PL3273942 T3 PL 3273942T3
Authority
PL
Poland
Prior art keywords
delivering
skin
active ingredient
microneedle patch
microneedle
Prior art date
Application number
PL16720351T
Other languages
English (en)
Inventor
Karsten Petersson
Karen Margrethe ENGELL
Jörgen Jansson
Kim Troensegaard Nielsen
André Huss ERIKSSON
Anne Moore
Sonja VUCEN
Caroline O'sullivan
Abina CREAN
Original Assignee
Leo Pharma A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma A/S filed Critical Leo Pharma A/S
Publication of PL3273942T3 publication Critical patent/PL3273942T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL16720351T 2015-03-27 2016-03-16 Plaster mikroigłowy do dostarczania składnika aktywnego do skóry PL3273942T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP15161262 2015-03-27
EP15176101 2015-07-09
EP16720351.2A EP3273942B1 (en) 2015-03-27 2016-03-16 Microneedle patch for delivering an active ingredient to the skin
PCT/EP2016/025026 WO2016155891A1 (en) 2015-03-27 2016-03-16 Microneedle patch for delivering an active ingredient to skin

Publications (1)

Publication Number Publication Date
PL3273942T3 true PL3273942T3 (pl) 2021-12-06

Family

ID=55910913

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16720351T PL3273942T3 (pl) 2015-03-27 2016-03-16 Plaster mikroigłowy do dostarczania składnika aktywnego do skóry

Country Status (20)

Country Link
US (2) US20180078498A1 (pl)
EP (1) EP3273942B1 (pl)
JP (1) JP6929784B2 (pl)
KR (1) KR20170131642A (pl)
CN (1) CN107405301B (pl)
AU (1) AU2016239277B2 (pl)
BR (1) BR112017020511A2 (pl)
CA (1) CA2979435A1 (pl)
DK (1) DK3273942T3 (pl)
ES (1) ES2886129T3 (pl)
HK (1) HK1246208A1 (pl)
IL (1) IL254183A0 (pl)
MA (1) MA41818A (pl)
MX (1) MX382471B (pl)
MY (1) MY191513A (pl)
PL (1) PL3273942T3 (pl)
SG (1) SG11201707141TA (pl)
UA (1) UA124141C2 (pl)
WO (1) WO2016155891A1 (pl)
ZA (2) ZA201706259B (pl)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2719937C1 (ru) 2014-04-24 2020-04-23 Джорджия Тек Рисёч Корпорейшн Микроиглы и способы их изготовления
US10940301B2 (en) 2015-04-17 2021-03-09 Georgia Tech Research Corporation Drug delivery devices having separable microneedles
WO2017209774A1 (en) * 2016-06-03 2017-12-07 Sanova Bioscience Inc Microneedle patch containing hyaluronic acid for cosmetic use
JP2020507422A (ja) * 2017-02-17 2020-03-12 アラーガン、インコーポレイテッドAllergan,Incorporated 活性成分を含むマイクロニードルアレイ
CN111465387B (zh) 2017-10-11 2024-07-26 乔治亚州技术研究公司 用于持续释放药物的可分离微针阵列
SG10201800072YA (en) * 2018-01-03 2019-08-27 Micropoint Tech Pte Ltd Microneedle Patches Comprising Corticosteroid
KR102094744B1 (ko) * 2018-01-26 2020-03-30 가천대학교 산학협력단 마이크로 니들 및 이의 제조방법
WO2019168926A1 (en) * 2018-02-28 2019-09-06 BandGrip, Inc. Subcutaneous wound closure assembly and method of use
CN112203664A (zh) * 2018-04-13 2021-01-08 北卡罗来纳州立大学 用于寻常性痤疮治疗的ros响应性微针贴剂
KR102146704B1 (ko) * 2018-04-13 2020-08-21 가천대학교 산학협력단 사이클로스포린 A (CsA) 경피 및 피내 약물전달용 마이크로구조체
CN112423829B (zh) * 2018-05-18 2023-03-28 浦项工科大学校产学协力团 经皮药物递送贴剂及其制造方法
US12121618B2 (en) 2018-05-18 2024-10-22 Postech Academy-Industry Foundation Transdermal drug delivery patch and manufacturing method thereof
CN108721204A (zh) * 2018-06-04 2018-11-02 南京紫源康医药科技有限公司 一种可溶性紫草素微针贴片及其制备方法
CN108703895B (zh) * 2018-08-21 2021-02-09 广州香蒲兰电子商务有限公司 一种深层渗透的长效保湿凝胶及制备方法
CN110870846A (zh) * 2018-08-31 2020-03-10 中科微针(北京)科技有限公司 一种可快速植入型缓释微针贴片及其制备方法
CN110917176B (zh) * 2018-08-31 2021-03-30 中科微针(北京)科技有限公司 一种可植入型缓释微针贴片及其制备方法
CN108888577B (zh) * 2018-09-11 2021-09-14 无锡元旭生物技术有限公司 一种可溶性玻尿酸美容微针贴及其制备方法
CN112752590A (zh) * 2018-09-24 2021-05-04 欧莱雅 包含用于皮肤原位反应的微针的装置
JP7666887B2 (ja) * 2018-12-21 2025-04-22 ロレアル マイクロニードルシートを使用するキット及び美容方法
GB201908229D0 (en) 2019-06-10 2019-07-24 Univ College Cork National Univ Of Ireland Microneedles and methods for the manufacture thereof
ES2966108T3 (es) * 2019-07-10 2024-04-18 Mineed Tech Company Limited Microaguja soluble
JP2022553337A (ja) * 2019-10-22 2022-12-22 ジョージア テック リサーチ コーポレイション 流延配合物中の成分溶解度の調整を使用してマイクロニードルを作製するための方法
WO2021087179A1 (en) * 2019-10-29 2021-05-06 The Regents Of The University Of California Periodontal micropatch and uses thereof
CA3159272A1 (en) * 2019-11-22 2021-05-27 Veradermics Incorporated Microneedle patch for immunostimulatory drug delivery
US20230015942A1 (en) * 2019-12-11 2023-01-19 The Regents Of The University Of California Microneedle delivery device with detachable hybrid microneedle depots for localized delivery of cells
US12186515B2 (en) 2020-04-28 2025-01-07 Ticona Llc Microneedle assembly
NL2026264B1 (en) 2020-08-13 2022-04-13 Versailles B V Microneedle applicator with active ingredient for treatment of skin lesions
HU231600B1 (hu) 2020-09-18 2025-03-28 Semmelweis Egyetem 40% Bőrtapasz a SARS-CoV-2 vírusfertőzöttség elleni immunvédettség celluláris diagnosztikai vizsgálatához
CN112294750B (zh) * 2020-10-29 2023-06-20 广东药科大学 一种吲哚美辛胶束复合微针及其制备方法
CN112516449B (zh) * 2020-12-03 2023-02-21 昆明理工大学 一种可溶性微针阵列及其制备方法
CA3212891A1 (en) * 2021-03-23 2022-09-29 Veradermics Incorporated Perilesional treatment of skin conditions
KR102778469B1 (ko) * 2021-04-12 2025-03-11 한미약품 주식회사 마이크로니들 어레이 및 이의 제조방법
JP2024519385A (ja) * 2021-05-21 2024-05-10 ベラデルミクス インコーポレイテッド 免疫賦活薬送達のためのマイクロニードルパッチ
CN115581659A (zh) * 2021-07-05 2023-01-10 刘野 一种非甾体类抗炎药微针及其制备方法
WO2023014375A1 (en) * 2021-08-06 2023-02-09 Lean Life Sciences, Inc Cosmetic peptides for improving skin rejuvenation
KR20230129639A (ko) * 2022-03-02 2023-09-11 연세대학교 산학협력단 이중작용 pde5 억제제/질산유기에스터의 국소 혈류 증진을 위한 경피 투약 형태
US20260021036A1 (en) * 2022-04-07 2026-01-22 Sheba Impact Ltd. Flexible biodegradable microneedles
WO2023218230A1 (en) * 2022-05-13 2023-11-16 Mineed Technology Company Limited Dissolvable microneedle patch
CN115317439A (zh) * 2022-07-18 2022-11-11 合肥博思科创医药科技有限公司 一种克立硼罗微针贴剂及其制备方法
CN116115552B (zh) * 2023-01-06 2025-01-17 山东第二医科大学 一种托法替布纳米微针制剂及其制备方法和应用
CN121443348A (zh) * 2023-06-21 2026-01-30 徐硕培 利用激光的药物注入用针贴片
CN117883362A (zh) * 2024-01-17 2024-04-16 中国医学科学院生物医学工程研究所 一种装载富马酸二甲酯的调节性t细胞外泌体微针及其制备方法与应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39706E1 (en) 1993-01-15 2007-06-26 Leo Pharma A/S Crystalline form of a vitamin D analogue
CA2370565C (en) * 1999-04-23 2008-11-25 Leo Pharma A/S Dermally applicable vitamin d-containing pharmaceutical compositions
DE60138411D1 (de) 2000-10-13 2009-05-28 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
WO2002064193A2 (en) 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
US6893431B2 (en) * 2001-10-15 2005-05-17 Scimed Life Systems, Inc. Medical device for delivering patches
CN101102809B (zh) * 2004-11-18 2010-05-26 3M创新有限公司 涂敷微针阵列的遮蔽方法
US7651946B2 (en) 2005-12-12 2010-01-26 University College Cork - National University Of Ireland, Cork Wet etch processing
CN1857730B (zh) * 2006-03-30 2010-05-12 西安交通大学 带微孔的多腔体可降解植入式药物控释载体及其制备工艺
US20090182306A1 (en) * 2006-07-21 2009-07-16 Georgia Tech Research Corporation Microneedle Devices and Methods of Drug Delivery or Fluid Withdrawal
US8821446B2 (en) 2007-01-22 2014-09-02 Corium International, Inc. Applicators for microneedles
JP2010522774A (ja) * 2007-03-30 2010-07-08 フォベア、ファルマスティカル、ソシエテ、アノニム 血管新生眼疾患を治療するための方法
CA2686093C (en) * 2007-04-16 2018-05-08 Corium International, Inc. Solvent-cast microneedle arrays containing active
AU2014200648B2 (en) * 2007-04-16 2015-09-24 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
WO2010074239A1 (ja) * 2008-12-26 2010-07-01 久光製薬株式会社 マイクロニードルデバイス
ES2719595T3 (es) * 2010-05-04 2019-07-11 Corium Int Inc Método y dispositivo para la administración transdérmica de la hormona paratiroidea usando una matriz de microproyección
GB201019577D0 (en) * 2010-11-18 2010-12-29 Univ Cork Method
GB201107642D0 (en) 2011-05-09 2011-06-22 Univ Cork Method
CN104027324B (zh) * 2013-03-06 2017-12-15 中国科学院理化技术研究所 一种可溶性微针疫苗贴片及其制备方法
BR112015022625B1 (pt) * 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
US10500386B2 (en) * 2013-07-30 2019-12-10 Asti Corporation Microneedle array manufacturing method
US20150057505A1 (en) * 2013-08-22 2015-02-26 Elwha Llc Method for Administering a Medicament to a Fetus

Also Published As

Publication number Publication date
RU2017134576A3 (pl) 2019-08-27
AU2016239277A1 (en) 2017-09-28
MA41818A (fr) 2018-01-30
ES2886129T3 (es) 2021-12-16
EP3273942A1 (en) 2018-01-31
IL254183A0 (en) 2017-10-31
ZA201706259B (en) 2018-12-19
BR112017020511A2 (pt) 2018-07-10
CN107405301A (zh) 2017-11-28
SG11201707141TA (en) 2017-10-30
KR20170131642A (ko) 2017-11-29
RU2017134576A (ru) 2019-04-04
ZA201806163B (en) 2019-12-18
AU2016239277B2 (en) 2019-01-24
MX382471B (es) 2025-03-13
MY191513A (en) 2022-06-28
UA124141C2 (uk) 2021-07-28
WO2016155891A1 (en) 2016-10-06
HK1246208A1 (zh) 2018-09-07
CA2979435A1 (en) 2016-10-06
US20180078498A1 (en) 2018-03-22
JP2018510170A (ja) 2018-04-12
DK3273942T3 (da) 2021-09-13
JP6929784B2 (ja) 2021-09-01
CN107405301B (zh) 2021-11-30
US20230404909A1 (en) 2023-12-21
EP3273942B1 (en) 2021-06-16
MX2017012321A (es) 2018-01-18

Similar Documents

Publication Publication Date Title
ZA201806163B (en) Microneedle patch for delivering an active ingredient to skin
ZA201805747B (en) Biologically active cannabidiol analogs
IL250660A0 (en) Skin sensors for drug delivery devices
IL253123A0 (en) Preparations for administration through the skin and their uses
SI3310904T1 (sl) Celični tarčni dostavni sistem za dostavo učinkovin
SG11201706081SA (en) Alum-containing coating formulations for microneedle vaccine patches
EP3391935A4 (en) MICRO NEEDLE AND MICRO NEEDLE STAMP
GB2535614B (en) A skin patch
EP3188721A4 (en) Human therapeutic agents
PL3235494T3 (pl) Preparat transdermalny zawierający donepezil jako składnik aktywny
GB201616070D0 (en) Skin cosmetic
EP3281626A4 (en) Soluble microneedle for delivering poorly-soluble drug
PT3103453T (pt) Composição medicinal compreendendo um composto de carboxamida heterocíclica diamina como ingrediente activo
GB2544813B (en) Devices and methods for delivering pharmaceuticals and cosmetics to the skin
EP3148556A4 (en) Skin treatment formulations
EP3213764A4 (en) Microneedle device containing recombinant follicle stimulating hormone
SG11201610636VA (en) Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor
GB201511126D0 (en) Spray device for the delivery of therapeutic agents
IL260119A (en) Galenic formulation comprising a topical drug
PT3431060T (pt) Adesivo para pele
GB201707679D0 (en) Device for delivering medicaments or active ingredients
GB201513556D0 (en) Patch for person's skin
PT3273942T (pt) Penso de microagulhas para administração de um ingrediente ativo na pele
TWM533991U (en) Skin patch
GB201711760D0 (en) Microneedle delivery system