PL2913058T3 - Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 - Google Patents
Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1Info
- Publication number
- PL2913058T3 PL2913058T3 PL13849289T PL13849289T PL2913058T3 PL 2913058 T3 PL2913058 T3 PL 2913058T3 PL 13849289 T PL13849289 T PL 13849289T PL 13849289 T PL13849289 T PL 13849289T PL 2913058 T3 PL2913058 T3 PL 2913058T3
- Authority
- PL
- Poland
- Prior art keywords
- novel method
- treating cardiac
- cardiac infarction
- hmgb1 fragment
- hmgb1
- Prior art date
Links
- 206010061216 Infarction Diseases 0.000 title 1
- 230000000747 cardiac effect Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 230000007574 infarction Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4718—Cytokine-induced proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012235785 | 2012-10-25 | ||
| EP13849289.7A EP2913058B1 (en) | 2012-10-25 | 2013-10-24 | Novel method for treating cardiac infarction using hmgb1 fragment |
| PCT/JP2013/078758 WO2014065347A1 (ja) | 2012-10-25 | 2013-10-24 | Hmgb1断片を利用した新規心筋梗塞の治療法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2913058T3 true PL2913058T3 (pl) | 2018-04-30 |
Family
ID=50544720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13849289T PL2913058T3 (pl) | 2012-10-25 | 2013-10-24 | Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9623078B2 (pl) |
| EP (1) | EP2913058B1 (pl) |
| JP (1) | JP6253589B2 (pl) |
| KR (1) | KR102146815B1 (pl) |
| CN (1) | CN104884076B (pl) |
| AU (1) | AU2013335684B2 (pl) |
| BR (1) | BR112015009037A2 (pl) |
| CA (1) | CA2889275C (pl) |
| DK (1) | DK2913058T3 (pl) |
| ES (1) | ES2660420T3 (pl) |
| MX (1) | MX361259B (pl) |
| PL (1) | PL2913058T3 (pl) |
| RU (1) | RU2647467C2 (pl) |
| SG (1) | SG11201503236RA (pl) |
| TR (1) | TR201802122T4 (pl) |
| WO (1) | WO2014065347A1 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110017371A (ko) | 2008-04-30 | 2011-02-21 | 가부시키가이샤 제노믹스 | 생체내 기능적 세포의 고효율 채취법 |
| KR20120135190A (ko) | 2009-10-28 | 2012-12-12 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제 |
| CN103687946B (zh) | 2011-04-26 | 2017-05-03 | 吉诺米克斯股份有限公司 | 用于诱导组织再生的肽及其应用 |
| PL2913058T3 (pl) | 2012-10-25 | 2018-04-30 | Genomix Co., Ltd. | Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 |
| CN104955470B (zh) | 2012-10-25 | 2017-06-16 | 吉诺米克斯股份有限公司 | 利用了hmgb1片段的针对脊髄损伤的新型治疗方法 |
| BR112019014921A2 (pt) * | 2017-01-27 | 2020-03-31 | StemRIM Inc. | Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica |
| CN110621331A (zh) * | 2017-04-07 | 2019-12-27 | 斯特姆里姆有限公司 | 纤维化疾病的治疗药物 |
| CA3059544A1 (en) * | 2017-04-25 | 2018-11-01 | Shionogi & Co., Ltd. | Peptide for inducing regeneration of tissue, and use thereof |
| JPWO2019107530A1 (ja) * | 2017-12-01 | 2020-11-26 | 株式会社ステムリム | 炎症性腸疾患の治療薬 |
| US12421498B2 (en) | 2017-12-01 | 2025-09-23 | StemRIM Inc. | Ectodermal mesenchymal stem cells and method for producing same |
| WO2019156137A1 (ja) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | 乾癬の治療薬 |
| US12304933B2 (en) | 2018-10-05 | 2025-05-20 | StemRIM Inc. | Disease treatment drug based on mesenchymal-stem-cell mobilization |
| US20220009976A1 (en) * | 2018-10-05 | 2022-01-13 | StemRIM Inc. | Peptide Possessing Mesenchymal-Stem-Cell Mobilizing Activity |
| EP3865179B1 (en) | 2018-10-25 | 2025-07-23 | The University of Osaka | Hmgb1 derived peptide for treating or preventing a cartilage disorder |
| WO2021094983A1 (en) | 2019-11-12 | 2021-05-20 | Oxford University Innovation Limited | Polypeptides related to hmgb1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof |
| RU2718912C1 (ru) * | 2019-12-24 | 2020-04-15 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт общей патологии и физиологии" (ФГБНУ "НИИОПП") | Способ лечения и профилактики инфаркта миокарда с патологией легких |
| EP4147711A4 (en) * | 2020-04-20 | 2024-04-24 | Shionogi & Co., Ltd | Formulation containing hmgb1 partial peptide |
| WO2022243932A1 (en) | 2021-05-19 | 2022-11-24 | Oxford University Innovation Limited | Polypeptides related to hmgb1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof |
| JP2025135028A (ja) * | 2022-06-30 | 2025-09-18 | 国立大学法人大阪大学 | 半月板の治療薬 |
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| JPS5238680B2 (pl) | 1972-12-27 | 1977-09-30 | ||
| US5658894A (en) | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| US5661127A (en) * | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
| JP3018313B2 (ja) * | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| DE60042828D1 (de) | 1999-07-28 | 2009-10-08 | Univ R | Nicotinrezeptoragonisten in stammzellen und vorlaüferzellinduktion |
| EP1114862A3 (de) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| AU4328801A (en) | 2000-02-24 | 2001-09-03 | Xcyte Therapies Inc | Simultaneous stimulation and concentration of cells |
| JP3421741B2 (ja) | 2000-05-18 | 2003-06-30 | 筑波大学長 | 人工骨髄、血球細胞の増殖方法 |
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| US7754217B2 (en) | 2001-03-16 | 2010-07-13 | Bio3 Research Srl | HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
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| EP1390058A2 (en) | 2001-04-30 | 2004-02-25 | Switch Biotech Aktiengesellschaft | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
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| GB0226251D0 (en) | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
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| EP1579221A2 (de) | 2003-01-03 | 2005-09-28 | Alcedo Biotech GmbH | Verwendungen von hmgb, hmgn, hmga proteinen |
| DE602004017148D1 (de) | 2003-03-28 | 2008-11-27 | Univ Laval | S100 protein als aktivator neutrophiler zellen zur verminderung der neutropenie bei der krebsbehandlung |
| US20050014255A1 (en) | 2003-05-29 | 2005-01-20 | Board Of Regents, The University Of Texas System | Stem cells for clinical and commercial uses |
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| ITRM20040058A1 (it) | 2004-02-03 | 2004-05-03 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali. |
| CA2574548A1 (en) | 2004-07-20 | 2006-01-26 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb1 for wound healing |
| MX2007001155A (es) | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| KR101249287B1 (ko) | 2004-09-03 | 2013-04-01 | 크리어빌리스 쎄라퓨틱스 에스.피.에이. | 인간 및 비인간 ｈｍｇｂ１ ｂｏｘａ의 단백질분해효소내성 돌연변이 및 그들의 치료／진단 용도 |
| KR100593397B1 (ko) | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 ｐ 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| WO2006047820A1 (en) | 2004-11-01 | 2006-05-11 | Newsouth Innovations Pty Limited | Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation |
| ITRM20050032A1 (it) | 2005-01-21 | 2006-07-22 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica. |
| US9782439B2 (en) | 2005-01-27 | 2017-10-10 | Japan Health Sciences Foundation | Cell sheet containing mesenchymal stem cells |
| CN101146559B (zh) | 2005-03-23 | 2012-09-05 | 生物安全股份有限公司 | 用于再生医学的收集、处理和移植包括成人干细胞的细胞亚群的集成系统 |
| WO2006114805A2 (en) | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb2 and hmgb3 proteins for medical applications |
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| WO2007031100A1 (en) | 2005-09-14 | 2007-03-22 | Ostini, Marco | Active immunotherapy of life-threatening systemic inflammation |
| WO2007130725A2 (en) * | 2006-02-06 | 2007-11-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of hmgb1 for protection against ischemia reperfusion injury |
| JP4982739B2 (ja) | 2006-06-01 | 2012-07-25 | 国立大学法人 東京医科歯科大学 | ポリグルタミン病の予防・治療剤 |
| ES2396220T3 (es) | 2006-08-11 | 2013-02-20 | Ono Pharmaceutical Co., Ltd. | Anticuerpos monoclonales frente al factor 1 derivado del estroma (SDF-1) |
| AU2007315073A1 (en) | 2006-10-30 | 2008-05-08 | Genomix Co., Ltd. | Pharmaceuticals that promote functional regeneration of damaged tissues |
| KR20110017371A (ko) | 2008-04-30 | 2011-02-21 | 가부시키가이샤 제노믹스 | 생체내 기능적 세포의 고효율 채취법 |
| AU2009240885A1 (en) | 2008-04-30 | 2009-11-05 | Genomix Co., Ltd. | Pharmaceutical agent for promoting the functional regeneration of damaged tissue |
| WO2009133939A1 (ja) | 2008-04-30 | 2009-11-05 | 株式会社ジェノミックス | 末梢循環への骨髄由来多能性幹細胞動員薬 |
| CA2777663A1 (en) | 2009-10-16 | 2011-04-21 | University Of Medicine And Dentistry Of New Jersey | Method for treating chronic nerve tissue injury using a cell therapy strategy |
| KR20120135190A (ko) | 2009-10-28 | 2012-12-12 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제 |
| CN103687946B (zh) * | 2011-04-26 | 2017-05-03 | 吉诺米克斯股份有限公司 | 用于诱导组织再生的肽及其应用 |
| CN102443064A (zh) * | 2011-11-03 | 2012-05-09 | 刘誉 | 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用 |
| CN104955470B (zh) | 2012-10-25 | 2017-06-16 | 吉诺米克斯股份有限公司 | 利用了hmgb1片段的针对脊髄损伤的新型治疗方法 |
| PL2913058T3 (pl) | 2012-10-25 | 2018-04-30 | Genomix Co., Ltd. | Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 |
-
2013
- 2013-10-24 PL PL13849289T patent/PL2913058T3/pl unknown
- 2013-10-24 MX MX2015005252A patent/MX361259B/es active IP Right Grant
- 2013-10-24 AU AU2013335684A patent/AU2013335684B2/en active Active
- 2013-10-24 ES ES13849289.7T patent/ES2660420T3/es active Active
- 2013-10-24 US US14/436,906 patent/US9623078B2/en active Active
- 2013-10-24 WO PCT/JP2013/078758 patent/WO2014065347A1/ja not_active Ceased
- 2013-10-24 RU RU2015119517A patent/RU2647467C2/ru active
- 2013-10-24 DK DK13849289.7T patent/DK2913058T3/en active
- 2013-10-24 TR TR2018/02122T patent/TR201802122T4/tr unknown
- 2013-10-24 KR KR1020157013590A patent/KR102146815B1/ko active Active
- 2013-10-24 JP JP2014543334A patent/JP6253589B2/ja active Active
- 2013-10-24 CN CN201380067948.2A patent/CN104884076B/zh active Active
- 2013-10-24 BR BR112015009037A patent/BR112015009037A2/pt not_active Application Discontinuation
- 2013-10-24 EP EP13849289.7A patent/EP2913058B1/en active Active
- 2013-10-24 CA CA2889275A patent/CA2889275C/en active Active
- 2013-10-24 SG SG11201503236RA patent/SG11201503236RA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2889275C (en) | 2021-06-15 |
| US9623078B2 (en) | 2017-04-18 |
| RU2015119517A (ru) | 2016-12-20 |
| MX361259B (es) | 2018-11-30 |
| MX2015005252A (es) | 2015-10-29 |
| AU2013335684B2 (en) | 2017-06-29 |
| KR20150103660A (ko) | 2015-09-11 |
| US20150273017A1 (en) | 2015-10-01 |
| EP2913058A1 (en) | 2015-09-02 |
| EP2913058B1 (en) | 2017-12-20 |
| HK1211488A1 (en) | 2016-05-27 |
| AU2013335684A1 (en) | 2015-05-14 |
| TR201802122T4 (tr) | 2018-03-21 |
| CN104884076B (zh) | 2017-10-03 |
| CN104884076A (zh) | 2015-09-02 |
| CA2889275A1 (en) | 2014-05-01 |
| JP6253589B2 (ja) | 2017-12-27 |
| WO2014065347A1 (ja) | 2014-05-01 |
| RU2647467C2 (ru) | 2018-03-15 |
| DK2913058T3 (en) | 2018-02-19 |
| KR102146815B1 (ko) | 2020-08-21 |
| EP2913058A4 (en) | 2016-04-13 |
| BR112015009037A2 (pt) | 2017-11-14 |
| HK1212887A1 (en) | 2016-06-24 |
| ES2660420T3 (es) | 2018-03-22 |
| JPWO2014065347A1 (ja) | 2016-09-08 |
| SG11201503236RA (en) | 2015-06-29 |
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