PL2913058T3 - Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 - Google Patents

Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1

Info

Publication number
PL2913058T3
PL2913058T3 PL13849289T PL13849289T PL2913058T3 PL 2913058 T3 PL2913058 T3 PL 2913058T3 PL 13849289 T PL13849289 T PL 13849289T PL 13849289 T PL13849289 T PL 13849289T PL 2913058 T3 PL2913058 T3 PL 2913058T3
Authority
PL
Poland
Prior art keywords
novel method
treating cardiac
cardiac infarction
hmgb1 fragment
hmgb1
Prior art date
Application number
PL13849289T
Other languages
English (en)
Inventor
Katsuto Tamai
Sokichi KAMATA
Yasufumi Kaneda
Shigeru Miyagawa
Yoshiki Sawa
Takehiko Yamazaki
Original Assignee
Genomix Co., Ltd.
Osaka University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomix Co., Ltd., Osaka University filed Critical Genomix Co., Ltd.
Publication of PL2913058T3 publication Critical patent/PL2913058T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4718Cytokine-induced proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
PL13849289T 2012-10-25 2013-10-24 Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 PL2913058T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012235785 2012-10-25
EP13849289.7A EP2913058B1 (en) 2012-10-25 2013-10-24 Novel method for treating cardiac infarction using hmgb1 fragment
PCT/JP2013/078758 WO2014065347A1 (ja) 2012-10-25 2013-10-24 Hmgb1断片を利用した新規心筋梗塞の治療法

Publications (1)

Publication Number Publication Date
PL2913058T3 true PL2913058T3 (pl) 2018-04-30

Family

ID=50544720

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13849289T PL2913058T3 (pl) 2012-10-25 2013-10-24 Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1

Country Status (17)

Country Link
US (1) US9623078B2 (pl)
EP (1) EP2913058B1 (pl)
JP (1) JP6253589B2 (pl)
KR (1) KR102146815B1 (pl)
CN (1) CN104884076B (pl)
AU (1) AU2013335684B2 (pl)
BR (1) BR112015009037A2 (pl)
CA (1) CA2889275C (pl)
DK (1) DK2913058T3 (pl)
ES (1) ES2660420T3 (pl)
HK (2) HK1211488A1 (pl)
MX (1) MX361259B (pl)
PL (1) PL2913058T3 (pl)
RU (1) RU2647467C2 (pl)
SG (1) SG11201503236RA (pl)
TR (1) TR201802122T4 (pl)
WO (1) WO2014065347A1 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9919010B2 (en) 2008-04-30 2018-03-20 Genomix Co., Ltd. Method for collecting functional cells in vivo with high efficiency
RU2599448C2 (ru) 2009-10-28 2016-10-10 Дженомикс Ко., Лтд. Средства для стимуляции регенерации тканей путем привлечения мезенхимных стволовых клеток и/или плюрипотентных стволовых клеток костного мозга в кровь
US10364276B2 (en) 2011-04-26 2019-07-30 StemRIM Inc. Peptide for inducing regeneration of tissue and use thereof
JP6253589B2 (ja) 2012-10-25 2017-12-27 株式会社ジェノミックス Hmgb1断片を利用した新規心筋梗塞の治療法
KR102146822B1 (ko) 2012-10-25 2020-08-21 가부시키가이샤 스템림 Hmgb1 단편을 이용한 척수 손상에 대한 신규 치료법
BR112019014921A2 (pt) * 2017-01-27 2020-03-31 StemRIM Inc. Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica
RU2019134382A (ru) * 2017-04-07 2021-05-07 Стемрим Инк. Лекарственное средство для лечения фиброзного заболевания
BR112019021230A2 (pt) * 2017-04-25 2020-06-02 Shionogi & Co., Ltd. Peptídeos, composições que os compreende e uso dos mesmos
EP3718561A4 (en) * 2017-12-01 2021-07-21 Stemrim Inc. Therapy for inflammatory bowel disease
EP3750553A4 (en) * 2018-02-08 2022-01-12 Stemrim Inc. THERAPEUTIC FOR PSORIASIS
EP3862017A4 (en) * 2018-10-05 2022-08-03 Stemrim Inc. PEPTIDE WITH MESENCHYMAL STEM CELL MOBILIZATION ACTIVITY
CA3117107A1 (en) 2018-10-25 2020-04-30 Osaka University Therapeutic agent for cartilage disorder
AU2020385059A1 (en) 2019-11-12 2022-06-02 Oxford University Innovation Limited Polypeptides related to HMGB1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof
RU2718912C1 (ru) * 2019-12-24 2020-04-15 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт общей патологии и физиологии" (ФГБНУ "НИИОПП") Способ лечения и профилактики инфаркта миокарда с патологией легких
US20230173027A1 (en) 2020-04-20 2023-06-08 Shionogi & Co., Ltd. Formulation containing hmgb1 partial peptide
JP2024518125A (ja) 2021-05-19 2024-04-24 オックスフォード ユニバーシティ イノベーション リミテッド 組織再生の促進に有用なhmgb1関連ポリペプチド、それを含む組成物及びその使用
WO2024005133A1 (ja) * 2022-06-30 2024-01-04 国立大学法人大阪大学 半月板の治療薬

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5238680B2 (pl) 1972-12-27 1977-09-30
US5658894A (en) 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US5661127A (en) * 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
JP3018313B2 (ja) 1996-02-23 2000-03-13 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
US20040031072A1 (en) 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
EP1207879B1 (en) 1999-07-28 2009-08-26 The Board Of Trustees Of The Leland Stanford Junior University Nicotine receptor agonists in stem cell and progenitor cell recruitment
EP1114862A3 (de) 1999-11-17 2003-08-06 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen
ATE373078T1 (de) 2000-02-24 2007-09-15 Xcyte Therapies Inc Gleichzeitige stimulation und konzentration von zellen
JP3421741B2 (ja) 2000-05-18 2003-06-30 筑波大学長 人工骨髄、血球細胞の増殖方法
US7754217B2 (en) 2001-03-16 2010-07-13 Bio3 Research Srl HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases
DE10121254A1 (de) 2001-04-30 2002-11-07 Switch Biotech Ag MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind
WO2002088181A2 (en) 2001-04-30 2002-11-07 Switch Biotech Ag Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances
CZ20033402A3 (cs) 2001-05-15 2004-10-13 Northáshore@Longáislandájewisháresearcháinstitute Použití fragmentů HMG jako protizánětlivých činidel
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
ITMI20011986A1 (it) 2001-09-25 2003-03-25 San Raffaele Centro Fond Metodo e composizione per l'attivazione di cellule presentanti l'antigene
US20040265971A1 (en) 2001-11-19 2004-12-30 Hidetaka Sato Drug mobilizing pluripotent stem cells from tissue into peripheral blood
CA2849201A1 (en) 2001-12-07 2003-07-03 Macropore Biosurgery, Inc. Adipose-derived cell processing unit
JP2005537253A (ja) 2002-07-03 2005-12-08 フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール 組織損傷の治療におけるおよび/または組織修復を促進するためのhmgb1の使用
EP1519749B1 (en) 2002-07-05 2009-04-08 Universite Laval Chemotactic factor inhibitor for inhibiting inflammatory reactions
GB0226251D0 (en) 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
JP2006510619A (ja) 2002-11-20 2006-03-30 クリティカル セラピューティクス,インコーポレイテッド 抗炎症剤としてのhmgb断片の使用
JP2006517537A (ja) 2003-01-03 2006-07-27 アルケド バイオテック ゲーエムベーハー Dna結合タンパク質の使用
WO2004075855A2 (en) 2003-02-26 2004-09-10 Biomed Solutions, Llc Process for in vivo treatment of specific biological targets in bodily fluid
ATE411038T1 (de) 2003-03-28 2008-10-15 Univ Laval S100 protein als aktivator neutrophiler zellen zur verminderung der neutropenie bei der krebsbehandlung
US20050014255A1 (en) 2003-05-29 2005-01-20 Board Of Regents, The University Of Texas System Stem cells for clinical and commercial uses
WO2005025604A2 (en) 2003-09-10 2005-03-24 The General Hospital Corporation Use of hmgb and hmgb fragments to decrease specific immune response
ITRM20040058A1 (it) 2004-02-03 2004-05-03 Marco E Bianchi Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali.
EP1768693A1 (en) 2004-07-20 2007-04-04 Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione - Istituto Dermopatico Dell'Immacolata Use of hmgb1 for wound healing
MX2007001155A (es) 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
EP1797118A2 (en) 2004-09-03 2007-06-20 Creabilis Therapeutics S.P.A. Protease resistant human and non-human hmgb1 box-a mutants and their therapeutic/diagnostic use
KR100593397B1 (ko) 2004-10-27 2006-06-28 한국원자력연구소 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제
WO2006047820A1 (en) 2004-11-01 2006-05-11 Newsouth Innovations Pty Limited Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation
ITRM20050032A1 (it) 2005-01-21 2006-07-22 Marco E Bianchi Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.
US9782439B2 (en) 2005-01-27 2017-10-10 Japan Health Sciences Foundation Cell sheet containing mesenchymal stem cells
JP4846782B2 (ja) 2005-03-23 2011-12-28 ビオセフ エス・アー 再生医療のための、成人幹細胞を含む細胞サブセットを採集、加工及び移植するための統合システム
WO2006114805A2 (en) 2005-04-28 2006-11-02 Fondazione Centro San Raffaele Del Monte Tabor Use of hmgb2 and hmgb3 proteins for medical applications
WO2007015546A1 (ja) 2005-08-04 2007-02-08 Genomix Co., Ltd 間葉系幹細胞誘導剤及び組織再生促進剤並びに間葉系幹細胞の調製方法
WO2007031100A1 (en) 2005-09-14 2007-03-22 Ostini, Marco Active immunotherapy of life-threatening systemic inflammation
US7829097B2 (en) * 2006-02-06 2010-11-09 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of HMGB1 for protection against ischemia reperfusion injury
JP4982739B2 (ja) 2006-06-01 2012-07-25 国立大学法人 東京医科歯科大学 ポリグルタミン病の予防・治療剤
US8496931B2 (en) 2006-08-11 2013-07-30 Medarex, Inc. Monoclonal antibodies against stromal derived factor-1 (SDF-1)
CN101374538A (zh) 2006-10-30 2009-02-25 吉诺米克斯股份有限公司 损伤组织的功能再生促进药物
AU2009240885A1 (en) 2008-04-30 2009-11-05 Genomix Co., Ltd. Pharmaceutical agent for promoting the functional regeneration of damaged tissue
RU2519714C2 (ru) 2008-04-30 2014-06-20 Дженомикс Ко., Лтд. Средство для вовлечения происходящей из костного мозга плюрипотентной стволовой клетки в периферический кровоток
US9919010B2 (en) 2008-04-30 2018-03-20 Genomix Co., Ltd. Method for collecting functional cells in vivo with high efficiency
WO2011046570A1 (en) 2009-10-16 2011-04-21 The University Of Medicine And Dentistry Of New Jersey Method for treating chronic nerve tissue injury using a cell therapy strategy
RU2599448C2 (ru) 2009-10-28 2016-10-10 Дженомикс Ко., Лтд. Средства для стимуляции регенерации тканей путем привлечения мезенхимных стволовых клеток и/или плюрипотентных стволовых клеток костного мозга в кровь
US10364276B2 (en) 2011-04-26 2019-07-30 StemRIM Inc. Peptide for inducing regeneration of tissue and use thereof
CN102443064A (zh) 2011-11-03 2012-05-09 刘誉 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用
KR102146822B1 (ko) 2012-10-25 2020-08-21 가부시키가이샤 스템림 Hmgb1 단편을 이용한 척수 손상에 대한 신규 치료법
JP6253589B2 (ja) 2012-10-25 2017-12-27 株式会社ジェノミックス Hmgb1断片を利用した新規心筋梗塞の治療法

Also Published As

Publication number Publication date
CN104884076B (zh) 2017-10-03
HK1211488A1 (en) 2016-05-27
AU2013335684B2 (en) 2017-06-29
RU2647467C2 (ru) 2018-03-15
MX2015005252A (es) 2015-10-29
SG11201503236RA (en) 2015-06-29
CA2889275A1 (en) 2014-05-01
CN104884076A (zh) 2015-09-02
US9623078B2 (en) 2017-04-18
AU2013335684A1 (en) 2015-05-14
TR201802122T4 (tr) 2018-03-21
RU2015119517A (ru) 2016-12-20
BR112015009037A2 (pt) 2017-11-14
KR102146815B1 (ko) 2020-08-21
US20150273017A1 (en) 2015-10-01
ES2660420T3 (es) 2018-03-22
JPWO2014065347A1 (ja) 2016-09-08
EP2913058B1 (en) 2017-12-20
JP6253589B2 (ja) 2017-12-27
WO2014065347A1 (ja) 2014-05-01
EP2913058A1 (en) 2015-09-02
HK1212887A1 (zh) 2016-06-24
KR20150103660A (ko) 2015-09-11
MX361259B (es) 2018-11-30
EP2913058A4 (en) 2016-04-13
CA2889275C (en) 2021-06-15
DK2913058T3 (en) 2018-02-19

Similar Documents

Publication Publication Date Title
HK1212887A1 (zh) 利用 片段的治療心肌梗塞的新型方法
FI3363806T3 (fi) Glykokonjugaatiomenetelmä
ZA201906339B (en) Methods for treating pruritus
ZA201208219B (en) Method for treating wasterwater
HK1209319A1 (en) Methods for treating hepatitis c
IL225623A0 (en) Psoriasis treatment methods
HRP20160851T1 (hr) Prediktori za liječenje karcinoma
HK1213201A1 (zh) 利用了 片段的針對脊髄損傷的新型治療方法
EP2924095A4 (en) PROCESS FOR THE PRODUCTION OF COKE
HK1202457A1 (en) Methods for treating parkinsons disease
SG11201501026TA (en) Composition for treating psoriasis
EP2816126A4 (en) THERMAL TREATMENT METHOD
HK1209320A1 (en) Methods for treating hepatitis c
EP2813142A4 (en) METHOD FOR THE INTRODUCTION OF FLORIGEN
EP2891644A4 (en) PROCESS FOR COLLECTING OLEFIN
HK1209040A1 (en) Methods for treating vestibulotoxicity
SG11201500505PA (en) Process for recovering power
EP2917309A4 (en) PROCESS FOR RECOVERING OLIGOMERATE
EP2838532A4 (en) PROCESS FOR TREATING SCLERRODERY