PL2888263T3 - Hapteny rysperydonu i paliperydonu - Google Patents
Hapteny rysperydonu i paliperydonuInfo
- Publication number
- PL2888263T3 PL2888263T3 PL13753972T PL13753972T PL2888263T3 PL 2888263 T3 PL2888263 T3 PL 2888263T3 PL 13753972 T PL13753972 T PL 13753972T PL 13753972 T PL13753972 T PL 13753972T PL 2888263 T3 PL2888263 T3 PL 2888263T3
- Authority
- PL
- Poland
- Prior art keywords
- paliperidone
- risperidone
- haptens
- Prior art date
Links
- PMXMIIMHBWHSKN-UHFFFAOYSA-N 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCC(O)C4=NC=3C)=NOC2=C1 PMXMIIMHBWHSKN-UHFFFAOYSA-N 0.000 title 1
- 229960001057 paliperidone Drugs 0.000 title 1
- 229960001534 risperidone Drugs 0.000 title 1
- RAPZEAPATHNIPO-UHFFFAOYSA-N risperidone Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCCC4=NC=3C)=NOC2=C1 RAPZEAPATHNIPO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/77—Ovalbumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261691469P | 2012-08-21 | 2012-08-21 | |
| EP13753972.2A EP2888263B1 (en) | 2012-08-21 | 2013-08-20 | Haptens of risperidone and paliperidone |
| PCT/US2013/055729 WO2014031601A1 (en) | 2012-08-21 | 2013-08-20 | Haptens of risperidone and paliperidone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2888263T3 true PL2888263T3 (pl) | 2018-10-31 |
Family
ID=49083786
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13753972T PL2888263T3 (pl) | 2012-08-21 | 2013-08-20 | Hapteny rysperydonu i paliperydonu |
| PL18171270T PL3415516T3 (pl) | 2012-08-21 | 2013-08-20 | Hapteny rysperydonu i paliperydonu |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18171270T PL3415516T3 (pl) | 2012-08-21 | 2013-08-20 | Hapteny rysperydonu i paliperydonu |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9012648B2 (pl) |
| EP (2) | EP3415516B1 (pl) |
| JP (2) | JP6131500B2 (pl) |
| CN (2) | CN104755479B (pl) |
| AU (1) | AU2013305936B2 (pl) |
| CA (1) | CA2882560C (pl) |
| ES (2) | ES2669565T3 (pl) |
| PL (2) | PL2888263T3 (pl) |
| PT (2) | PT3415516T (pl) |
| TR (1) | TR201809424T4 (pl) |
| WO (1) | WO2014031601A1 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2870004T3 (es) * | 2012-08-21 | 2021-10-26 | Janssen Pharmaceutica Nv | Anticuerpos contra la risperidona y uso de los mismos |
| EP2888285B1 (en) | 2012-08-21 | 2024-04-17 | Janssen Pharmaceutica NV | Antibodies to aripiprazole haptens and use thereof |
| WO2014031584A1 (en) | 2012-08-21 | 2014-02-27 | Janssen Pharmaceutica Nv | Haptens of aripiprazole and their use in immunoassays |
| HK1211958A1 (en) | 2012-08-21 | 2016-06-03 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone and use thereof |
| CN107253993B (zh) | 2012-08-21 | 2021-10-22 | 詹森药业有限公司 | 奥氮平的抗体及其用途 |
| TR201910347T4 (tr) | 2012-08-21 | 2019-07-22 | Janssen Pharmaceutica Nv | Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı. |
| ES2788716T3 (es) | 2012-08-21 | 2020-10-22 | Janssen Pharmaceutica Nv | Anticuerpos para haptenos de quetiapina y uso de los mismos |
| AU2013305936B2 (en) * | 2012-08-21 | 2017-08-03 | Saladax Biomedical Inc. | Haptens of risperidone and paliperidone |
| CA2882615C (en) | 2012-08-21 | 2019-07-09 | Ortho-Clinical Diagnostics, Inc. | Antibodies to quetiapine and use thereof |
| CN104736566A (zh) | 2012-08-21 | 2015-06-24 | 奥索临床诊断有限公司 | 帕潘立酮半抗原的抗体及其用途 |
| ES2762105T3 (es) | 2012-08-21 | 2020-05-22 | Janssen Pharmaceutica Nv | Anticuerpos para aripiprazol y uso de los mismos |
| EP2888284B1 (en) * | 2012-08-21 | 2022-07-06 | Janssen Pharmaceutica NV | Antibodies to risperidone haptens and use thereof |
| CA3008809A1 (en) * | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
| JP6994461B2 (ja) | 2015-12-17 | 2022-02-04 | ヤンセン ファーマシューティカ エヌ．ベー． | クエチアピンに対する抗体及びその使用 |
| CN107137715B (zh) * | 2017-04-26 | 2019-02-19 | 石家庄蒎格医药科技有限公司 | 一种帕利哌酮聚乙二醇缀合前药及制备 |
| CN110938072A (zh) * | 2019-10-30 | 2020-03-31 | 杭州博拓生物科技股份有限公司 | 一种利培酮人工抗原及其制备方法 |
| CN112608310B (zh) * | 2020-12-17 | 2022-03-29 | 北京丹大生物技术有限公司 | 一种利培酮和9-羟基利培酮半抗原、抗原和抗体以及其应用 |
| CN114685470B (zh) * | 2020-12-25 | 2023-08-18 | 长沙博源医疗科技有限公司 | 一种利培酮关键基团衍生物、免疫原、抗利培酮特异性抗体及其制备方法与应用 |
| CN116003404B (zh) * | 2022-12-14 | 2024-10-01 | 杭州同舟生物技术有限公司 | 一种利培酮人工半抗原、人工抗原及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| US6034078A (en) | 1992-05-29 | 2000-03-07 | Eli Lilly And Company Limited | Thienobenzodiazepine compounds |
| EP0582368B1 (en) | 1992-05-29 | 2001-01-24 | Eli Lilly And Company Limited | Thienobenzodiazepine derivatives for treatment of CNS disorders |
| US5395933A (en) | 1992-08-07 | 1995-03-07 | Eastman Kodak Company | Carbamazepine hapten analogues |
| US6958156B2 (en) | 2000-12-15 | 2005-10-25 | Vyrex Corporation | Isoflavone derivatives |
| CA2479932A1 (en) | 2002-03-28 | 2003-10-09 | Eli Lilly And Company | Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders |
| PT1546134E (pt) | 2002-08-05 | 2007-08-10 | Lilly Co Eli | ''arilbenzodiazepinas substituídas com piperazina'' |
| PT1664007E (pt) | 2003-09-23 | 2010-02-15 | Fermion Oy | Preparação de quetiapina |
| TW200616604A (en) | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
| US20080214808A1 (en) * | 2005-04-25 | 2008-09-04 | Thomas Frederik Ernestine Spittaels | Preparation of Aseptic 3-[2-[4-((6-Fluoro-1,2-Benzisoxazol-3-Yl)-1-Piperidinyl]-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One Palmitate Ester |
| CN101245065B (zh) * | 2007-02-14 | 2010-05-19 | 江苏恩华药业股份有限公司 | 制备苯并异噁唑衍生物的方法及其中间体 |
| MX2010003259A (es) | 2007-09-27 | 2010-04-12 | Novartis Ag | Ensayo de monitoreo de farmacos. |
| US20100069356A1 (en) | 2008-09-17 | 2010-03-18 | Auspex Pharmaceuticals, Inc. | Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors |
| UY32174A (es) | 2008-10-14 | 2010-05-31 | Astrazeneca Ab | Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones |
| EP2194048A1 (en) | 2008-12-02 | 2010-06-09 | Dirk Sartor | Nitrate esters for the treatment of vascular and metabolic diseases |
| CN104586859B (zh) | 2009-12-31 | 2017-12-05 | 凯姆制药公司 | 喹硫平的氨基酸缀合物、其制备和使用方法 |
| US20110166156A1 (en) * | 2010-01-07 | 2011-07-07 | Alkermes, Inc. | Prodrugs for the Treatment of Schizophrenia and Bipolar Disease |
| DK2544536T3 (en) | 2010-03-11 | 2019-02-04 | Kempharm Inc | FAT ACID CONJUGATES OF QUETIAPIN, METHOD OF PREPARING IT AND USING IT |
| US8088594B2 (en) | 2010-03-16 | 2012-01-03 | Saladax Biomedical Inc. | Risperidone immunoassay |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| US8623324B2 (en) | 2010-07-21 | 2014-01-07 | Aat Bioquest Inc. | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates |
| US8969337B2 (en) | 2011-12-15 | 2015-03-03 | Alkermes Pharma Ireland Limited | Prodrugs of secondary amine compounds |
| AU2013305936B2 (en) * | 2012-08-21 | 2017-08-03 | Saladax Biomedical Inc. | Haptens of risperidone and paliperidone |
-
2013
- 2013-08-20 AU AU2013305936A patent/AU2013305936B2/en active Active
- 2013-08-20 CA CA2882560A patent/CA2882560C/en active Active
- 2013-08-20 PL PL13753972T patent/PL2888263T3/pl unknown
- 2013-08-20 US US13/970,673 patent/US9012648B2/en active Active
- 2013-08-20 PT PT181712704T patent/PT3415516T/pt unknown
- 2013-08-20 PL PL18171270T patent/PL3415516T3/pl unknown
- 2013-08-20 PT PT137539722T patent/PT2888263T/pt unknown
- 2013-08-20 CN CN201380055010.9A patent/CN104755479B/zh active Active
- 2013-08-20 ES ES13753972.2T patent/ES2669565T3/es active Active
- 2013-08-20 WO PCT/US2013/055729 patent/WO2014031601A1/en not_active Ceased
- 2013-08-20 EP EP18171270.4A patent/EP3415516B1/en active Active
- 2013-08-20 CN CN201610907378.9A patent/CN107082778A/zh active Pending
- 2013-08-20 EP EP13753972.2A patent/EP2888263B1/en active Active
- 2013-08-20 JP JP2015528572A patent/JP6131500B2/ja active Active
- 2013-08-20 TR TR2018/09424T patent/TR201809424T4/tr unknown
- 2013-08-20 ES ES18171270T patent/ES2904838T3/es active Active
-
2017
- 2017-03-30 JP JP2017066729A patent/JP6667472B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2882560A1 (en) | 2014-02-27 |
| ES2669565T3 (es) | 2018-05-28 |
| HK1211930A1 (en) | 2016-06-03 |
| PL3415516T3 (pl) | 2022-03-28 |
| EP2888263B1 (en) | 2018-05-09 |
| JP2015526470A (ja) | 2015-09-10 |
| JP6131500B2 (ja) | 2017-05-24 |
| TR201809424T4 (tr) | 2018-07-23 |
| JP6667472B2 (ja) | 2020-03-18 |
| EP3415516B1 (en) | 2021-12-15 |
| PT2888263T (pt) | 2018-07-30 |
| CN104755479A (zh) | 2015-07-01 |
| WO2014031601A1 (en) | 2014-02-27 |
| PT3415516T (pt) | 2022-01-28 |
| EP2888263A1 (en) | 2015-07-01 |
| CN107082778A (zh) | 2017-08-22 |
| CA2882560C (en) | 2020-10-27 |
| JP2017149731A (ja) | 2017-08-31 |
| US9012648B2 (en) | 2015-04-21 |
| US20140155585A1 (en) | 2014-06-05 |
| EP3415516A1 (en) | 2018-12-19 |
| ES2904838T3 (es) | 2022-04-06 |
| CN104755479B (zh) | 2016-11-09 |
| AU2013305936A1 (en) | 2015-03-05 |
| AU2013305936B2 (en) | 2017-08-03 |
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