PL2888263T3 - Hapteny rysperydonu i paliperydonu - Google Patents

Hapteny rysperydonu i paliperydonu

Info

Publication number
PL2888263T3
PL2888263T3 PL13753972T PL13753972T PL2888263T3 PL 2888263 T3 PL2888263 T3 PL 2888263T3 PL 13753972 T PL13753972 T PL 13753972T PL 13753972 T PL13753972 T PL 13753972T PL 2888263 T3 PL2888263 T3 PL 2888263T3
Authority
PL
Poland
Prior art keywords
paliperidone
risperidone
haptens
Prior art date
Application number
PL13753972T
Other languages
English (en)
Inventor
Pieter Rik HASPESLAGH
Maarten VLIEGEN
Eric Hryhorenko
Thomas R. DECORY
Banumathi Sankaran
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PL2888263T3 publication Critical patent/PL2888263T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/77Ovalbumin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL13753972T 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu PL2888263T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261691469P 2012-08-21 2012-08-21
PCT/US2013/055729 WO2014031601A1 (en) 2012-08-21 2013-08-20 Haptens of risperidone and paliperidone
EP13753972.2A EP2888263B1 (en) 2012-08-21 2013-08-20 Haptens of risperidone and paliperidone

Publications (1)

Publication Number Publication Date
PL2888263T3 true PL2888263T3 (pl) 2018-10-31

Family

ID=49083786

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18171270T PL3415516T3 (pl) 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu
PL13753972T PL2888263T3 (pl) 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL18171270T PL3415516T3 (pl) 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu

Country Status (11)

Country Link
US (1) US9012648B2 (pl)
EP (2) EP3415516B1 (pl)
JP (2) JP6131500B2 (pl)
CN (2) CN107082778A (pl)
AU (1) AU2013305936B2 (pl)
CA (1) CA2882560C (pl)
ES (2) ES2904838T3 (pl)
PL (2) PL3415516T3 (pl)
PT (2) PT2888263T (pl)
TR (1) TR201809424T4 (pl)
WO (1) WO2014031601A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201809424T4 (tr) * 2012-08-21 2018-07-23 Janssen Pharmaceutica Nv Risperidon ve paliperidon haptenleri.
AU2013305965B2 (en) 2012-08-21 2017-08-24 Saladax Biomedical Inc. Antibodies to paliperidone and use thereof
CN104755928B (zh) 2012-08-21 2017-05-10 詹森药业有限公司 奥氮平的抗体及其用途
ES2762105T3 (es) 2012-08-21 2020-05-22 Janssen Pharmaceutica Nv Anticuerpos para aripiprazol y uso de los mismos
WO2014031668A2 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to quetiapine and use thereof
TR201816416T4 (tr) 2012-08-21 2018-11-21 Janssen Pharmaceutica Nv Risperidona yönelik antikorlar ve bunların kullanımı.
JP6374387B2 (ja) 2012-08-21 2018-08-15 ヤンセン ファーマシューティカ エヌ.ベー. リスペリドンハプテンへの抗体及びその使用
ES2822914T3 (es) 2012-08-21 2021-05-05 Janssen Pharmaceutica Nv Haptenos de aripiprazol y su uso en inmunoensayos
PT3663317T (pt) 2012-08-21 2023-01-23 Janssen Pharmaceutica Nv Anticorpos para haptenos de quetiapina e sua utilização
CN104755093B (zh) 2012-08-21 2018-11-16 詹森药业有限公司 奥氮平半抗原的抗体及其用途
ES2978909T3 (es) 2012-08-21 2024-09-23 Janssen Pharmaceutica Nv Anticuerpos contra haptenos de aripiprazol y uso de los mismos
CA2882489A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone haptens and use thereof
AU2016370853A1 (en) 2015-12-17 2018-06-07 Saladax Biomedical Inc. Antibodies to quetiapine and use thereof
CN108431040B (zh) * 2015-12-17 2022-07-26 詹森药业有限公司 利培酮的抗体及其用途
CN107137715B (zh) * 2017-04-26 2019-02-19 石家庄蒎格医药科技有限公司 一种帕利哌酮聚乙二醇缀合前药及制备
CN110938072A (zh) * 2019-10-30 2020-03-31 杭州博拓生物科技股份有限公司 一种利培酮人工抗原及其制备方法
CN112608310B (zh) * 2020-12-17 2022-03-29 北京丹大生物技术有限公司 一种利培酮和9-羟基利培酮半抗原、抗原和抗体以及其应用
CN114685470B (zh) * 2020-12-25 2023-08-18 长沙博源医疗科技有限公司 一种利培酮关键基团衍生物、免疫原、抗利培酮特异性抗体及其制备方法与应用
CN116003404B (zh) * 2022-12-14 2024-10-01 杭州同舟生物技术有限公司 一种利培酮人工半抗原、人工抗原及其制备方法和应用

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EP0582368B1 (en) 1992-05-29 2001-01-24 Eli Lilly And Company Limited Thienobenzodiazepine derivatives for treatment of CNS disorders
US5395933A (en) 1992-08-07 1995-03-07 Eastman Kodak Company Carbamazepine hapten analogues
US6958156B2 (en) 2000-12-15 2005-10-25 Vyrex Corporation Isoflavone derivatives
ATE380818T1 (de) 2002-03-28 2007-12-15 Lilly Co Eli Piperazine-substituierte aryl-benzodiazepinen und ihre verwendung als dopaminrezeptor-antagonisten zur behandlung von psychose
ES2285227T3 (es) 2002-08-05 2007-11-16 Eli Lilly And Company Arilbenzodiazepinas sustituidas con piperazina.
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CN101245065B (zh) * 2007-02-14 2010-05-19 江苏恩华药业股份有限公司 制备苯并异噁唑衍生物的方法及其中间体
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WO2011084850A1 (en) * 2010-01-07 2011-07-14 Alkermes, Inc. Prodrugs for the treatment of schizophrenia and bipolar disease
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US8088594B2 (en) 2010-03-16 2012-01-03 Saladax Biomedical Inc. Risperidone immunoassay
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
US8623324B2 (en) 2010-07-21 2014-01-07 Aat Bioquest Inc. Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates
WO2013088255A1 (en) 2011-12-15 2013-06-20 Alkermes Pharma Ireland Limited Prodrugs of secondary amine compounds
TR201809424T4 (tr) * 2012-08-21 2018-07-23 Janssen Pharmaceutica Nv Risperidon ve paliperidon haptenleri.

Also Published As

Publication number Publication date
CN104755479B (zh) 2016-11-09
US20140155585A1 (en) 2014-06-05
AU2013305936B2 (en) 2017-08-03
AU2013305936A1 (en) 2015-03-05
EP3415516A1 (en) 2018-12-19
EP2888263A1 (en) 2015-07-01
CN104755479A (zh) 2015-07-01
PL3415516T3 (pl) 2022-03-28
EP2888263B1 (en) 2018-05-09
JP6667472B2 (ja) 2020-03-18
CN107082778A (zh) 2017-08-22
JP2015526470A (ja) 2015-09-10
JP2017149731A (ja) 2017-08-31
PT3415516T (pt) 2022-01-28
WO2014031601A1 (en) 2014-02-27
JP6131500B2 (ja) 2017-05-24
ES2669565T3 (es) 2018-05-28
CA2882560C (en) 2020-10-27
ES2904838T3 (es) 2022-04-06
US9012648B2 (en) 2015-04-21
HK1211930A1 (en) 2016-06-03
PT2888263T (pt) 2018-07-30
TR201809424T4 (tr) 2018-07-23
CA2882560A1 (en) 2014-02-27
EP3415516B1 (en) 2021-12-15

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