PL2888263T3 - Hapteny rysperydonu i paliperydonu - Google Patents
Hapteny rysperydonu i paliperydonuInfo
- Publication number
- PL2888263T3 PL2888263T3 PL13753972T PL13753972T PL2888263T3 PL 2888263 T3 PL2888263 T3 PL 2888263T3 PL 13753972 T PL13753972 T PL 13753972T PL 13753972 T PL13753972 T PL 13753972T PL 2888263 T3 PL2888263 T3 PL 2888263T3
- Authority
- PL
- Poland
- Prior art keywords
- paliperidone
- risperidone
- haptens
- Prior art date
Links
- PMXMIIMHBWHSKN-UHFFFAOYSA-N 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCC(O)C4=NC=3C)=NOC2=C1 PMXMIIMHBWHSKN-UHFFFAOYSA-N 0.000 title 1
- 229960001057 paliperidone Drugs 0.000 title 1
- 229960001534 risperidone Drugs 0.000 title 1
- RAPZEAPATHNIPO-UHFFFAOYSA-N risperidone Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCCC4=NC=3C)=NOC2=C1 RAPZEAPATHNIPO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/77—Ovalbumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261691469P | 2012-08-21 | 2012-08-21 | |
| PCT/US2013/055729 WO2014031601A1 (en) | 2012-08-21 | 2013-08-20 | Haptens of risperidone and paliperidone |
| EP13753972.2A EP2888263B1 (en) | 2012-08-21 | 2013-08-20 | Haptens of risperidone and paliperidone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2888263T3 true PL2888263T3 (pl) | 2018-10-31 |
Family
ID=49083786
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13753972T PL2888263T3 (pl) | 2012-08-21 | 2013-08-20 | Hapteny rysperydonu i paliperydonu |
| PL18171270T PL3415516T3 (pl) | 2012-08-21 | 2013-08-20 | Hapteny rysperydonu i paliperydonu |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18171270T PL3415516T3 (pl) | 2012-08-21 | 2013-08-20 | Hapteny rysperydonu i paliperydonu |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9012648B2 (pl) |
| EP (2) | EP3415516B1 (pl) |
| JP (2) | JP6131500B2 (pl) |
| CN (2) | CN104755479B (pl) |
| AU (1) | AU2013305936B2 (pl) |
| CA (1) | CA2882560C (pl) |
| ES (2) | ES2904838T3 (pl) |
| PL (2) | PL2888263T3 (pl) |
| PT (2) | PT3415516T (pl) |
| TR (1) | TR201809424T4 (pl) |
| WO (1) | WO2014031601A1 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110054693A (zh) | 2012-08-21 | 2019-07-26 | 詹森药业有限公司 | 喹硫平半抗原的抗体及其用途 |
| ES2762105T3 (es) | 2012-08-21 | 2020-05-22 | Janssen Pharmaceutica Nv | Anticuerpos para aripiprazol y uso de los mismos |
| HK1211958A1 (en) | 2012-08-21 | 2016-06-03 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone and use thereof |
| EP2888592B1 (en) | 2012-08-21 | 2017-11-08 | Janssen Pharmaceutica NV | Antibodies to quetiapine and use thereof |
| EP3415516B1 (en) * | 2012-08-21 | 2021-12-15 | Janssen Pharmaceutica NV | Haptens of risperidone and paliperidone |
| ES2822914T3 (es) | 2012-08-21 | 2021-05-05 | Janssen Pharmaceutica Nv | Haptenos de aripiprazol y su uso en inmunoensayos |
| CA2882563C (en) * | 2012-08-21 | 2022-11-29 | Eric Hryhorenko | Antibodies to risperidone haptens and use thereof |
| ES2733963T3 (es) | 2012-08-21 | 2019-12-03 | Janssen Pharmaceutica Nv | Anticuerpos contra haptenos de olanzapina y uso de los mismos |
| CA2882489A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone haptens and use thereof |
| PT2888590T (pt) | 2012-08-21 | 2020-09-11 | Janssen Pharmaceutica Nv | Anticorpos para olanzapina e utilização destes |
| US9664700B2 (en) * | 2012-08-21 | 2017-05-30 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
| CN104736567B (zh) | 2012-08-21 | 2019-09-03 | 詹森药业有限公司 | 阿立哌唑半抗原的抗体及其用途 |
| CN108431040B (zh) * | 2015-12-17 | 2022-07-26 | 詹森药业有限公司 | 利培酮的抗体及其用途 |
| US10435478B2 (en) | 2015-12-17 | 2019-10-08 | Janssen Pharmaceutica Nv | Antibodies to quetiapine and use thereof |
| CN107137715B (zh) * | 2017-04-26 | 2019-02-19 | 石家庄蒎格医药科技有限公司 | 一种帕利哌酮聚乙二醇缀合前药及制备 |
| CN110938072A (zh) * | 2019-10-30 | 2020-03-31 | 杭州博拓生物科技股份有限公司 | 一种利培酮人工抗原及其制备方法 |
| CN112608310B (zh) * | 2020-12-17 | 2022-03-29 | 北京丹大生物技术有限公司 | 一种利培酮和9-羟基利培酮半抗原、抗原和抗体以及其应用 |
| CN114685470B (zh) * | 2020-12-25 | 2023-08-18 | 长沙博源医疗科技有限公司 | 一种利培酮关键基团衍生物、免疫原、抗利培酮特异性抗体及其制备方法与应用 |
| CN116003404B (zh) * | 2022-12-14 | 2024-10-01 | 杭州同舟生物技术有限公司 | 一种利培酮人工半抗原、人工抗原及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| ES2153373T3 (es) | 1992-05-29 | 2001-03-01 | Lilly Co Eli | Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central. |
| US6034078A (en) | 1992-05-29 | 2000-03-07 | Eli Lilly And Company Limited | Thienobenzodiazepine compounds |
| US5395933A (en) | 1992-08-07 | 1995-03-07 | Eastman Kodak Company | Carbamazepine hapten analogues |
| US6958156B2 (en) | 2000-12-15 | 2005-10-25 | Vyrex Corporation | Isoflavone derivatives |
| JP2005533009A (ja) | 2002-03-28 | 2005-11-04 | イーライ・リリー・アンド・カンパニー | ピペラジン置換されたアリールベンゾジアゼピン類およびそのドーパミン受容体アンタゴニストとしての精神病性障害の処置のための使用 |
| ES2285227T3 (es) | 2002-08-05 | 2007-11-16 | Eli Lilly And Company | Arilbenzodiazepinas sustituidas con piperazina. |
| US7863441B2 (en) | 2003-09-23 | 2011-01-04 | Fermion Oy | Preparation of quetiapine |
| TW200616604A (en) | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
| WO2006114384A1 (en) * | 2005-04-25 | 2006-11-02 | Janssen Pharmaceutica N.V. | Preparation of aseptic 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4h-pyridio[1,2-a]pyrimidin-4-one palmitate ester |
| CN101245065B (zh) * | 2007-02-14 | 2010-05-19 | 江苏恩华药业股份有限公司 | 制备苯并异噁唑衍生物的方法及其中间体 |
| CN101809447A (zh) | 2007-09-27 | 2010-08-18 | 诺瓦提斯公司 | 药物监测方法 |
| WO2010033270A1 (en) | 2008-09-17 | 2010-03-25 | Auspex Pharmaceuticals, Inc. | Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors |
| EA201100613A1 (ru) | 2008-10-14 | 2011-12-30 | Астразенека Аб | Конденсированные, спироциклические гетероароматические соединения для лечения бактериальных инфекций |
| EP2194048A1 (en) | 2008-12-02 | 2010-06-09 | Dirk Sartor | Nitrate esters for the treatment of vascular and metabolic diseases |
| CN102781236B (zh) | 2009-12-31 | 2015-01-07 | 凯姆制药公司 | 喹硫平的氨基酸缀合物、其制备和使用方法 |
| US20110166156A1 (en) * | 2010-01-07 | 2011-07-07 | Alkermes, Inc. | Prodrugs for the Treatment of Schizophrenia and Bipolar Disease |
| EP2544536B1 (en) | 2010-03-11 | 2018-12-12 | Kempharm, Inc. | Fatty acid conjugates of quetiapine, process for making and using the same |
| US8088594B2 (en) * | 2010-03-16 | 2012-01-03 | Saladax Biomedical Inc. | Risperidone immunoassay |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| US8623324B2 (en) | 2010-07-21 | 2014-01-07 | Aat Bioquest Inc. | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates |
| AU2012351747B2 (en) | 2011-12-15 | 2016-05-12 | Alkermes Pharma Ireland Limited | Prodrugs of secondary amine compounds |
| EP3415516B1 (en) * | 2012-08-21 | 2021-12-15 | Janssen Pharmaceutica NV | Haptens of risperidone and paliperidone |
-
2013
- 2013-08-20 EP EP18171270.4A patent/EP3415516B1/en active Active
- 2013-08-20 PL PL13753972T patent/PL2888263T3/pl unknown
- 2013-08-20 JP JP2015528572A patent/JP6131500B2/ja active Active
- 2013-08-20 ES ES18171270T patent/ES2904838T3/es active Active
- 2013-08-20 TR TR2018/09424T patent/TR201809424T4/tr unknown
- 2013-08-20 ES ES13753972.2T patent/ES2669565T3/es active Active
- 2013-08-20 WO PCT/US2013/055729 patent/WO2014031601A1/en not_active Ceased
- 2013-08-20 US US13/970,673 patent/US9012648B2/en active Active
- 2013-08-20 PT PT181712704T patent/PT3415516T/pt unknown
- 2013-08-20 CN CN201380055010.9A patent/CN104755479B/zh active Active
- 2013-08-20 PT PT137539722T patent/PT2888263T/pt unknown
- 2013-08-20 CN CN201610907378.9A patent/CN107082778A/zh active Pending
- 2013-08-20 PL PL18171270T patent/PL3415516T3/pl unknown
- 2013-08-20 CA CA2882560A patent/CA2882560C/en active Active
- 2013-08-20 AU AU2013305936A patent/AU2013305936B2/en active Active
- 2013-08-20 EP EP13753972.2A patent/EP2888263B1/en active Active
-
2017
- 2017-03-30 JP JP2017066729A patent/JP6667472B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6131500B2 (ja) | 2017-05-24 |
| ES2904838T3 (es) | 2022-04-06 |
| AU2013305936B2 (en) | 2017-08-03 |
| US9012648B2 (en) | 2015-04-21 |
| EP3415516A1 (en) | 2018-12-19 |
| CA2882560C (en) | 2020-10-27 |
| CN104755479A (zh) | 2015-07-01 |
| JP2015526470A (ja) | 2015-09-10 |
| WO2014031601A1 (en) | 2014-02-27 |
| ES2669565T3 (es) | 2018-05-28 |
| EP2888263B1 (en) | 2018-05-09 |
| CN107082778A (zh) | 2017-08-22 |
| PT3415516T (pt) | 2022-01-28 |
| AU2013305936A1 (en) | 2015-03-05 |
| JP6667472B2 (ja) | 2020-03-18 |
| JP2017149731A (ja) | 2017-08-31 |
| EP3415516B1 (en) | 2021-12-15 |
| HK1211930A1 (en) | 2016-06-03 |
| PL3415516T3 (pl) | 2022-03-28 |
| PT2888263T (pt) | 2018-07-30 |
| US20140155585A1 (en) | 2014-06-05 |
| EP2888263A1 (en) | 2015-07-01 |
| TR201809424T4 (tr) | 2018-07-23 |
| CN104755479B (zh) | 2016-11-09 |
| CA2882560A1 (en) | 2014-02-27 |
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