PL2781221T3 - Lek do leczenia i/lub uzyskiwania poprawy w posocznicy - Google Patents
Lek do leczenia i/lub uzyskiwania poprawy w posocznicyInfo
- Publication number
- PL2781221T3 PL2781221T3 PL12850047T PL12850047T PL2781221T3 PL 2781221 T3 PL2781221 T3 PL 2781221T3 PL 12850047 T PL12850047 T PL 12850047T PL 12850047 T PL12850047 T PL 12850047T PL 2781221 T3 PL2781221 T3 PL 2781221T3
- Authority
- PL
- Poland
- Prior art keywords
- sepsis
- medicine
- improvement
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/366—Thrombomodulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/56—Protease inhibitors from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Botany (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161559864P | 2011-11-15 | 2011-11-15 | |
| PCT/JP2012/079449 WO2013073545A1 (ja) | 2011-11-15 | 2012-11-14 | 敗血症の治療及び／又は改善のための医薬 |
| EP12850047.7A EP2781221B9 (en) | 2011-11-15 | 2012-11-14 | Medicine for treatment and/or improvement of sepsis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2781221T3 true PL2781221T3 (pl) | 2020-08-24 |
Family
ID=48429601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12850047T PL2781221T3 (pl) | 2011-11-15 | 2012-11-14 | Lek do leczenia i/lub uzyskiwania poprawy w posocznicy |
Country Status (19)
| Country | Link |
|---|---|
| US (5) | US8772239B2 (pl) |
| EP (1) | EP2781221B9 (pl) |
| JP (2) | JP5902195B2 (pl) |
| KR (1) | KR101672108B1 (pl) |
| CN (1) | CN103974710B (pl) |
| AU (1) | AU2012337838B2 (pl) |
| BR (1) | BR112014011488B1 (pl) |
| CA (1) | CA2854882C (pl) |
| DK (1) | DK2781221T3 (pl) |
| ES (1) | ES2795439T3 (pl) |
| HK (1) | HK1196289A1 (pl) |
| HU (1) | HUE050698T2 (pl) |
| IL (1) | IL232434B (pl) |
| MX (1) | MX354981B (pl) |
| PL (1) | PL2781221T3 (pl) |
| PT (1) | PT2781221T (pl) |
| RU (1) | RU2580756C2 (pl) |
| WO (1) | WO2013073545A1 (pl) |
| ZA (1) | ZA201403494B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101672108B1 (ko) | 2011-11-15 | 2016-11-02 | 아사히 가세이 파마 가부시키가이샤 | 패혈증의 치료 및/또는 개선을 위한 의약 |
| WO2014210031A1 (en) * | 2013-06-25 | 2014-12-31 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
| US9730983B2 (en) * | 2015-10-02 | 2017-08-15 | Chih-Yuan MA | Methods for treatment of CD14-mediated disorders and responses |
| PL3682247T3 (pl) * | 2017-09-13 | 2022-04-25 | B.R.A.H.M.S Gmbh | Proadrenomedulina jako marker nieprawidłowych poziomów płytek krwi |
| KR20210049143A (ko) | 2018-09-28 | 2021-05-04 | 아사히 가세이 파마 가부시키가이샤 | 항악성 종양제에 의한 말초 신경 장애의 증상 경감 및/또는 발증 억제를 위한 의약 |
| US11497795B2 (en) | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
| MX2021004511A (es) * | 2018-10-22 | 2021-06-08 | Asahi Kasei Pharma Corp | Medicamento para el tratamiento y/o mejora de la septicemia asociada con la anomalia de la coagulacion. |
| CN110894494B (zh) * | 2019-11-22 | 2022-09-27 | 广西梧州制药（集团）股份有限公司 | 一种大规模高密度悬浮培养293细胞高产腺病毒的方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0816495A1 (en) | 1987-01-08 | 1998-01-07 | Asahi Kasei Kogyo Kabushiki Kaisha | DNA coding for a peptide promoting the activation of protein C by thrombin and dprocess for producing the same |
| JP2738428B2 (ja) | 1987-01-08 | 1998-04-08 | 旭化成工業株式会社 | トロンビンによるプロテインｃの活性化を促進する作用を有するペプチド |
| EP0285511B1 (en) | 1987-04-01 | 1992-11-25 | Mitsubishi Gas Chemical Company, Inc. | Immunoassay of thrombomodulin |
| DK299087D0 (da) | 1987-06-12 | 1987-06-12 | Novo Industri As | Proteins and derivatives thereof |
| JPS6445398A (en) | 1987-08-13 | 1989-02-17 | Kowa Co | Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody |
| JPH0720997B2 (ja) | 1988-08-29 | 1995-03-08 | 興和株式会社 | 新規なトロンビン結合性物質及びその製法 |
| US5202421A (en) | 1988-12-27 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant substance obtained from urine and process for the preparation thereof |
| JPH0798840B2 (ja) | 1988-12-27 | 1995-10-25 | 持田製薬株式会社 | 尿由来の抗血液疑固物質、その製法およびそれを含有する医薬組成物 |
| JPH02255699A (ja) | 1989-03-28 | 1990-10-16 | Asahi Chem Ind Co Ltd | 新規血液抗凝固物質及びその製法 |
| US6063763A (en) | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
| US5466668A (en) | 1989-04-28 | 1995-11-14 | Schering Aktiengesellschaft | Superior thrombomodulin analogs for pharmaceutical use |
| CA2022713A1 (en) | 1989-08-11 | 1991-02-12 | Nils U. Bang | Human thrombomodulin derivatives |
| JPH03259084A (ja) | 1990-03-06 | 1991-11-19 | Kowa Co | トロンビン結合性物質の製造法 |
| WO1992000325A1 (en) | 1990-06-27 | 1992-01-09 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
| KR930008093B1 (ko) | 1990-08-03 | 1993-08-25 | 아사히가세이고오교 가부시끼가이샤 | 신규 폴리펩티드 및 이를 유효성분으로 하는 의약조성물 |
| JPH05213998A (ja) | 1990-08-03 | 1993-08-24 | Asahi Chem Ind Co Ltd | 新規なポリペプチド及びこれを有効成分とする 医薬組成物 |
| WO1992003149A1 (en) | 1990-08-15 | 1992-03-05 | Berlex Laboratories, Inc. | Superior thrombomodulin analogs for pharmaceutical use |
| JP3220174B2 (ja) | 1990-12-12 | 2001-10-22 | 第一製薬株式会社 | 組換ヒトトロンボモジュリン誘導体 |
| EP1449849A3 (en) | 1992-02-05 | 2006-01-25 | Paion Deutschland GmbH | Protease-resistant thrombomodulin analog |
| JPH05310787A (ja) | 1992-05-01 | 1993-11-22 | Asahi Chem Ind Co Ltd | 新規なポリペプチド |
| JPH06205692A (ja) | 1993-01-08 | 1994-07-26 | Asahi Chem Ind Co Ltd | 新規な抗ヒトトロンボモジュリンモノクロ−ナル抗体およびその抗体を用いたヒトトロンボモジュリンの高感度測定方法 |
| JP3007785B2 (ja) | 1993-03-16 | 2000-02-07 | 旭化成工業株式会社 | トロンボモジュリン組成物およびその変性防止方法 |
| JP2824392B2 (ja) | 1994-05-31 | 1998-11-11 | 旭化成工業株式会社 | トロンビンによるプロテインｃの活性化を促進する作用を有するペプチドを含有する培養上澄液 |
| JP3745805B2 (ja) | 1995-10-24 | 2006-02-15 | 日本ケミカルリサーチ株式会社 | トロンボモジュリンの精製方法 |
| JP4157644B2 (ja) | 1998-03-30 | 2008-10-01 | 旭化成ファーマ株式会社 | 高純度可溶性トロンボモジュリンの製造方法 |
| PL372138A1 (pl) | 2001-10-15 | 2005-07-11 | Chiron Corporation | Leczenie posocznicy przez podawanie małych dawek inhibitora szlaku czynnika tkankowego (TFPI) |
| WO2003061687A1 (en) | 2002-01-18 | 2003-07-31 | Asahi Kasei Pharma Corporation | High-concentration preparation of soluble thrombomodulin |
| US8293710B2 (en) | 2005-01-03 | 2012-10-23 | Blue Blood Biotech Corp. | Method for treating wounds using an EGF-like domain of thrombomodulin |
| WO2008038777A1 (fr) * | 2006-09-29 | 2008-04-03 | Asahi Kasei Pharma Corporation | Agent thérapeutique pour le syndrome de coagulation intravasculaire disséminée |
| EP2754447A3 (en) | 2006-12-12 | 2014-11-12 | Indiana University Research and Technology Corporation | Treating acute renal failure with soluble thrombomodulin variants |
| NZ579873A (en) * | 2007-03-23 | 2011-11-25 | Asahi Kasei Pharma Corp | Method for producing soluble thrombomodulin of high purity |
| AR067345A1 (es) | 2007-07-10 | 2009-10-07 | Paion Deutschland Gmbh | Uso de trombomodulina para la preparacion de un medicamento trombolitico |
| US20110144024A1 (en) | 2008-07-16 | 2011-06-16 | Paion Deutschland Gmbh | Prevention and treatment of radiation injury |
| DE202009007655U1 (de) | 2009-05-29 | 2009-08-13 | Design Ballendat Gmbh | Kettenstuhl |
| KR101672108B1 (ko) | 2011-11-15 | 2016-11-02 | 아사히 가세이 파마 가부시키가이샤 | 패혈증의 치료 및/또는 개선을 위한 의약 |
| JP6441759B2 (ja) | 2015-07-24 | 2018-12-19 | 株式会社堀場製作所 | 分光分析器に用いられる光検出器の出力補正方法 |
-
2012
- 2012-11-14 KR KR1020147016082A patent/KR101672108B1/ko active IP Right Grant
- 2012-11-14 WO PCT/JP2012/079449 patent/WO2013073545A1/ja active Application Filing
- 2012-11-14 PT PT128500477T patent/PT2781221T/pt unknown
- 2012-11-14 ES ES12850047T patent/ES2795439T3/es active Active
- 2012-11-14 US US13/676,248 patent/US8772239B2/en active Active
- 2012-11-14 RU RU2014124171/15A patent/RU2580756C2/ru active
- 2012-11-14 CN CN201280055832.2A patent/CN103974710B/zh active Active
- 2012-11-14 CA CA2854882A patent/CA2854882C/en active Active
- 2012-11-14 EP EP12850047.7A patent/EP2781221B9/en active Active
- 2012-11-14 MX MX2014005895A patent/MX354981B/es active IP Right Grant
- 2012-11-14 HU HUE12850047A patent/HUE050698T2/hu unknown
- 2012-11-14 US US14/358,115 patent/US9592275B2/en active Active
- 2012-11-14 JP JP2013544281A patent/JP5902195B2/ja active Active
- 2012-11-14 BR BR112014011488-9A patent/BR112014011488B1/pt active IP Right Grant
- 2012-11-14 AU AU2012337838A patent/AU2012337838B2/en active Active
- 2012-11-14 DK DK12850047.7T patent/DK2781221T3/da active
- 2012-11-14 PL PL12850047T patent/PL2781221T3/pl unknown
-
2013
- 2013-05-17 US US13/897,100 patent/US20130244926A1/en not_active Abandoned
-
2014
- 2014-05-04 IL IL232434A patent/IL232434B/en active IP Right Grant
- 2014-05-14 ZA ZA2014/03494A patent/ZA201403494B/en unknown
- 2014-05-21 US US14/283,976 patent/US9034823B2/en active Active
- 2014-10-02 HK HK14109850.4A patent/HK1196289A1/zh unknown
-
2016
- 2016-02-16 JP JP2016026491A patent/JP2016104803A/ja active Pending
- 2016-08-02 US US15/226,195 patent/US9555080B2/en active Active
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