PL2640709T3 - Związki pirymidynohydroksyamidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania” - Google Patents

Związki pirymidynohydroksyamidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania”

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Publication number
PL2640709T3
PL2640709T3 PL11840803.8T PL11840803T PL2640709T3 PL 2640709 T3 PL2640709 T3 PL 2640709T3 PL 11840803 T PL11840803 T PL 11840803T PL 2640709 T3 PL2640709 T3 PL 2640709T3
Authority
PL
Poland
Prior art keywords
methods
amide compounds
deacetylase inhibitors
hydroxy amide
protein deacetylase
Prior art date
Application number
PL11840803.8T
Other languages
English (en)
Polish (pl)
Inventor
Duzer John H. Van
Ralph Mazitschek
Yanbing Ding
Nan Yu
Yun Cao
Yong Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46047943&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2640709(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of PL2640709T3 publication Critical patent/PL2640709T3/pl

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    • C—CHEMISTRY; METALLURGY
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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PL11840803.8T 2010-11-16 2011-11-15 Związki pirymidynohydroksyamidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania” PL2640709T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41415810P 2010-11-16 2010-11-16
US201161503286P 2011-06-30 2011-06-30

Publications (1)

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PL2640709T3 true PL2640709T3 (pl) 2016-10-31

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PL11840803.8T PL2640709T3 (pl) 2010-11-16 2011-11-15 Związki pirymidynohydroksyamidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania”

Country Status (19)

Country Link
US (3) US8614223B2 (https=)
EP (2) EP3067346A1 (https=)
JP (2) JP6041808B2 (https=)
KR (1) KR20130115300A (https=)
CN (2) CN103429574B (https=)
AU (2) AU2011329028B2 (https=)
BR (1) BR112013011868A2 (https=)
CA (1) CA2818125A1 (https=)
CL (1) CL2013001381A1 (https=)
EA (2) EA025345B1 (https=)
ES (1) ES2568260T3 (https=)
IL (2) IL226326A0 (https=)
MX (1) MX2013005392A (https=)
NZ (2) NZ710405A (https=)
PH (2) PH12013500964A1 (https=)
PL (1) PL2640709T3 (https=)
PT (1) PT2640709T (https=)
SG (2) SG10201509324QA (https=)
WO (1) WO2012068109A2 (https=)

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TWI600638B (zh) 2010-01-22 2017-10-01 艾斯特隆製藥公司 作爲蛋白質去乙醯酶抑制劑之反式醯胺化合物及其使用方法
BR112013011868A2 (pt) 2010-11-16 2016-08-23 Acetylon Pharmaceuticals Inc compostos de pirimidina hidróxi amida como inibidores da proteína desacetilase, composição farmacêutica e uso dos referidos compostos
US20150087687A1 (en) 2012-03-23 2015-03-26 Dennis Brown Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo
EP2839037B1 (en) 2012-04-19 2018-12-26 Acetylon Pharmaceuticals, Inc. Biomarkers to identify patients that will respond to treatment and treating such patients
WO2014059306A1 (en) * 2012-10-12 2014-04-17 The Trustees Of The University Of Pennsylvania Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
US9145412B2 (en) 2012-11-02 2015-09-29 Acetylon Pharmaceuticals, Inc. Selective HDAC1 and HDAC2 inhibitors
EP2968233A4 (en) 2013-03-14 2016-08-03 Chdi Foundation Inc HISTON DEACETYLASE HEMMER AND COMPOSITIONS AND METHOD FOR USE THEREOF
US9617259B2 (en) 2013-03-14 2017-04-11 Chdi Foundation, Inc. Histone deacetylase inhibitors and compositions and methods of use thereof
JP2016531163A (ja) * 2013-09-20 2016-10-06 アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． Ｈｄａｃ６阻害物質を用いた、異常なリンパ球の機能に起因する疾患の治療
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